*  A genetic variation of the transcription factor 7-like 2 gene is associated with risk of type 2 diabetes in the Japanese...
Recently, variants of TCF7L2 gene were reported to confer an increased risk of type 2 diabetes in three different samples from ... suggests that TCF7L2 is a common susceptibility gene for type 2 diabetes. ... It has been suggested that transcription factor 7-like 2 protein (TCF7L2) plays an important role in glucose metabolism by ... A genetic variation of the transcription factor 7-like 2 gene is associated with risk of type 2 diabetes in the Japanese ...
  https://www.semanticscholar.org/paper/A-genetic-variation-of-the-transcription-factor-2-2-Horikoshi-Hara/886689cea71264f90785f9e2d669d94b5cb5b4ea
*  A high-resolution gene expression atlas of epistasis between gene-specific transcription factors exposes potential mechanisms...
Genetic interactionsMolecular mechanismsGene-specific transcription factors Saccharomyces cerevisiae Background. Predicting the ... This is in part mediated by gene-specific transcription factors (GSTFs). Understanding the basis of genetic interactions ... Here, we have investigated the nature of genetic interactions between gene-specific transcription factors in baker's yeast. ... To investigate the nature of genetic interactions between gene-specific transcription factors (GSTFs) in Saccharomyces ...
  https://0-bmcbiol-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/s12915-015-0222-5
*  Genetic and Physical Interactions between Microphthalmia Transcription Factor and PU.1 Are Necessary for Osteoclast Gene...
Genetic and Physical Interactions between Microphthalmia Transcription Factor and PU.1 Are Necessary for Osteoclast Gene ... The microphthalmia transcription factor (MITF), a basic-helix-loop-helix zipper factor, regulates distinct target genes in ... how lineage-specific gene regulation can be achieved by the combinatorial action of two broadly expressed transcription factors ... We hypothesized that interaction with the Ets family factor PU.1, whose expression is limited to hematopoietic cells, might be ...
  https://research-repository.griffith.edu.au/handle/10072/63181
*  PAX6 - Wikipedia
Freund C, Horsford DJ, McInnes RR (1996). "Transcription factor genes and the developing eye: a genetic perspective". Human ... transcription factor activity, sequence-specific DNA binding. • transcription factor binding. • protein kinase binding. • ... As a transcription factor, Pax6 activates and/or deactivates gene expression patterns to ensure for proper development of the ... U.S. Pax6 is a gene in prenatal development referred to as a transcription factor (activator and repressor). This means that ...
  https://en.wikipedia.org/wiki/PAX6
*  Phenotype of autosomal recessive congenital microphthalmia mapping to chromosome 14q32 | British Journal of Ophthalmology
1996) Transcription factor genes and the developing eye: a genetic perspective. Hum Mol Genet 5:1471-1488. ... At least 14 transcription factors that are essential for normal mammalian eye development have been described, along with 32 ... Four transcription factors (PAX2, PAX3,PAX6, and CRX) have been associated with ocular disease in humans, but none has been ... is syntenic with a region of mouse chromosome 12 which contains a number of transcription factors, some of which are important ...
  http://bjo.bmj.com/content/83/8/919
*  Journal of Alzheimer's Disease - Volume 13, issue 3 - Journals - IOS Press
Keywords: Alzheimer's disease, genetic association, gene variation, mitochondria transcription factor DOI: 10.3233/JAD-2008- ... The TFAM-gene encodes the mitochondrial transcription factor A, a protein that controls the transcription, replication, damage ... Mitochondrial Transcription Factor A (TFAM) Gene Variation and Risk of Late-Onset Alzheimer's Disease ... Impact Factor 2017: 3.731. The Journal of Alzheimer's Disease is an international multidisciplinary journal to facilitate ...
  https://content.iospress.com/journals/journal-of-alzheimers-disease/13/3
*  Snel B[au] - PubMed - NCBI
... gene expression atlas of epistasis between gene-specific transcription factors exposes potential mechanisms for genetic ... Arabidopsis PLETHORA transcription factors control phyllotaxis.. Prasad K, Grigg SP, Barkoulas M, Yadav RK, Sanchez-Perez GF, ... Large-scale genetic perturbations reveal regulatory networks and an abundance of gene-specific repressors. ... The phylogeny of C/S1 bZIP transcription factors reveals a shared algal ancestry and the pre-angiosperm translational ...
  https://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Snel+B%5Bau%5D&dispmax=50
*  Hypopituitarism - The Clinical Advisor
A number of genetic mutations in genes encoding transcription factors necessary for differentiation of anterior pituitary cells ... PROP-1 gene mutations are the most common known cause of genetic MPHD and may occur as familial MPHD or sporadically. ... Congenital pituitary transcription factor defects may lead to formation of only a very small pituitary gland and the appearance ... Congenital hypopituitarism is due to pituitary dysplasia or tissue-specific transcription factor mutations. Pituitary dysplasia ...
  https://www.clinicaladvisor.com/endocrinology-metabolism/hypopituitarism/article/595547/
*  Genetic factors in pathogenesis of diabetes mellitus after kidney tran | TCRM
The commonly evaluated genetic determinants include genes encoding transcription factors, cytokines, chemokines, adipokines, ... There is a need for large genome-wide association study to identify the genetic risk factors associated with PTDM development. ... Currently, predisposing genetic factors have been considered important in PTDM development. ... The modifiable risk factors that contribute to PTDM include obesity, some viral infections (eg, hepatitis C virus, ...
  https://www.dovepress.com/genetic-factors-in-pathogenesis-of-diabetes-mellitus-after-kidney-tran-peer-reviewed-article-TCRM
*  Frontiers | Stress Inducible Expression of AtDREB1A Transcription Factor in Transgenic Peanut (Arachis hypogaea L.) Conferred...
GG20) lines were developed using AtDREB1A gene, encoding for a transcription factor, through Agrobacterium-mediated genetic ... GG20) lines were developed using AtDREB1A gene, encoding for a transcription factor, through Agrobacterium-mediated genetic ... one of the important strategies is to genetically engineer the ruling peanut varieties using transcription factor regulating ... The inheritance of AtDREB1A gene in individual transgenic plants (T1 and T2) was confirmed using PCR. In homozygous transgenic ...
  https://www.frontiersin.org/articles/10.3389/fpls.2016.00935/full
*  softdrink and flavoured low fat milk - AnabolicMinds.com
The fructose in sucrose induces undesirable genetic changes in liver transcription factors and various fat-storing genes. Not ... The fructose in sucrose induces undesirable genetic changes in liver transcription factors and various fat-storing genes. Not ...
  http://anabolicminds.com/forum/weight-loss/73166-softdrink-flavoured-low.html
*  Frontiers | A mathematical model of metabolism and regulation provides a systems-level view of how Escherichia coli responds to...
Variables of the model are metabolite concentrations, gene expression levels, transcription factor activities, metabolic fluxes ... Variables of the model are metabolite concentrations, gene expression levels, transcription factor activities, metabolic fluxes ... Mathematical modeling has the potential to provide a coherent and quantitative description of the interplay between gene ... Mathematical modeling has the potential to provide a coherent and quantitative description of the interplay between gene ...
  https://www.frontiersin.org/articles/10.3389/fmicb.2014.00124/full
*  Hidden Viral Gene Discovered In GMO Crops - Slashdot
TRANSCRIPTION FACTORS. GENE. PROTEIN. The PROMOTER is a genetic sequence that comes UPSTREAM of a GENE which is recognized by ... TRANSCRIPTION FACTORS. TRANSCRIPTION FACTORS bind to PROMOTER sequences and start the transcription of the GENE found ... 1. Why is that viral gene in there? When you insert a new gene (such as an herbicide resistance gene in Monsanto's Roundup ... I'm no expert on the matter, but from my knowledge genetic engineering is usually done by isolating a desirable gene, ...
  https://science.slashdot.org/story/13/01/22/2324246/hidden-viral-gene-discovered-in-gmo-crops?sdsrc=prevbtmprev
*  TEAD3 TEA domain transcription factor 3 [Homo sapiens (human)] - Gene - NCBI
Find tests for this gene in the NIH Genetic Testing Registry (GTR) ... TEAD3 TEA domain transcription factor 3 [Homo sapiens] TEAD3 TEA domain transcription factor 3 [Homo sapiens]. Gene ID:7005 ... This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the ... Gene Ontology Provided by GOA Function. Evidence Code. Pubs. DNA binding transcription factor activity IBA Inferred from ...
  https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=7005
*  Genetic and Epigenetic Mechanisms of β-Globin Gene Switching | SpringerLink
Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter binding, ... The phenomenon of stage-specific transcription of globin genes is referred to as globin gene switching. Mechanisms of ... The active spatial organization of the beta-globin locus requires the transcription factor EKLF, Genes Dev., 18, 2485-2490. ... Van der Vliet, P. C., and Verrijzer, C. P. (1993) Bending of DNA by transcription factors, BioEssays, 15, 25-32.PubMedCrossRef ...
  https://link.springer.com/article/10.1134/S0006297918040090
*  Similar articles for PubMed (Select 17606985) - PubMed - NCBI
Comprehensive genetic analysis of transcription factor pathways using a dual reporter gene system in budding yeast. ... Regulation of prion gene expression by transcription factors SP1 and metal transcription factor-1. ... Transcription factor hStaf/ZNF143 is required for expression of the human TFAM gene. ... Corepressor CtBP and nuclear speckle protein Pnn/DRS differentially modulate transcription and splicing of the E-cadherin gene. ...
  https://www.ncbi.nlm.nih.gov/pubmed?linkname=pubmed_pubmed&from_uid=17606985
*  Immunocompetence - definition of immunocompetence by The Free Dictionary
Genetic polymorphisms of pituitary-specific transcription factor-1 (Pit-1) gene from Indonesian local goat population reared in ... Phenotypic diversity, major genes and production potential of local chickens and guinea fowl in Tamale, northern Ghana ... Risk factors include baseline immunocompetence of the patient, presence of comorbid conditions, and patient age (Kleinpell & ... 1] Factors which influence immunocompetence are immune senescence, changes in non-adaptive immunity, chronic diseases, ...
  http://www.thefreedictionary.com/immunocompetence
*  JCI Insight - Restoration of lymphatic function rescues obesity in Prox1-haploinsufficient mice
Genetic variation in the human winged helix/forkhead transcription factor gene FOXC2 in Pima Indians. Diabetes. 2003;52(5):1292 ... Transcription factor forkhead box protein C2 (FOXC2), a gene required for formation and maturation of collecting vessels, ... it is now clear that additional factors (e.g., genetic inheritance, hormonal disorders, and aging) also contribute to obesity. ... A model for gene therapy of human hereditary lymphedema. Proc Natl Acad Sci U S A. 2001;98(22):12677-12682.. View this article ...
  https://insight.jci.org/articles/view/85096
*  Rice Cytokinin GATA Transcription Factor1 Regulates Chloroplast Development and Plant Architecture | Plant Physiology
2005) Genetic analysis of Arabidopsis GATA transcription factor gene family reveals a nitrate-inducible member important for ... 2008) Two GATA transcription factors are downstream effectors of floral homeotic gene action in Arabidopsis. Plant Physiol 147 ... 2011) Ectopic expression of different cytokinin-regulated transcription factor genes of Arabidopsis thaliana alters plant ... The CYTOKININ-RESPONSIVE GATA TRANSCRIPTION FACTOR1/GNC-like (CGA1/GNL) transcription factor was originally identified in ...
  http://www.plantphysiol.org/content/162/1/132
*  Hes1 - Transcription factor HES-1 - Mus musculus (Mouse) - Hes1 gene & protein
Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of ... regulation of transcription by RNA polymerase II Source: MGI ,p>Inferred from Genetic Interaction,/p> ,p>Used to describe " ... Transcription factor HES-1Add BLAST. 282. Proteomic databases. PaxDb, a database of protein abundance averages across all three ... RNA polymerase II transcription factor activity, sequence-specific DNA binding Source: MGI ,p>Inferred from Direct Assay,/p> ,p ...
  https://www.uniprot.org/uniprot/P35428
*  Genetic and Physiological Activation of Osmosensitive Gene Expression Mimics Transcriptional Signatures of Pathogen Infection...
Computational, transgenic, and functional approaches revealed that two GATA transcription factors previously implicated in ... Microarray profiling of wild type worms exposed to non-lethal hypertonicity identified a suite of genes that were also ... transcriptional similarities which might be controlled via regulation of tissue-specific GATA transcription factors. ... are also essential for coordinated tissue-specific activation of osmosensitive gene expression and promote survival under ...
  http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0009010
*  New method of detecting metalloproteins could lead to complete understanding of cell biology : science
... we know tonnes of information about different genetic pathways, which genes activate which transcription factors which then go ... on to activate whatever genes, but the end result of these pathways are still unknown. What is the final protein, what exactly ...
  https://www.reddit.com/r/science/comments/d28mg/new_method_of_detecting_metalloproteins_could/
*  Nfya - Nuclear transcription factor Y subunit alpha - Mus musculus (Mouse) - Nfya gene & protein
NF-YA positively regulates the transcription of the core clock component ARNTL/BMAL1. ... box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its ... Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' ... sequence-specific DNA binding Source: MGI ,p>Inferred from Genetic Interaction,/p> ,p>Used to describe "traditional" genetic ...
  http://www.uniprot.org/uniprot/P23708
*  Oncogenic Transcription Factors: Target Genes
... are a class of proteins that are essential for the regulation of gene expression and for the control of protein expression in ... Figure 1. Transcription factor (TF) activation and signalling pathway in cancer. TF activity is triggered by genetic ... Libermann TA and Zerbini LF (2006) Targeting transcription factors for cancer gene therapy. Current Gene Therapy 6 (1): 17-33. ... Transcription factors (TFs) are a class of proteins that are essential for the regulation of gene expression and for the ...
  http://www.els.net/WileyCDA/ElsArticle/refId-a0006049.html
*  Seed genome hypomethylated regions are enriched in transcription factor genes | PNAS
2014) Genetic control of identity and growth in the early Arabidopsis embryo. Biochem Soc Trans 42:346-351. ... Significantly, DMVs are enriched greatly in transcription factor (TF) genes and other developmental genes that play critical ... We searched seed DMVs for genes and scored identified genes as DMV genes if they had their gene bodies and 1 kb of 5′ and 3′ ... Seed genome hypomethylated regions are enriched in transcription factor genes. Min Chen, Jer-Young Lin, Jungim Hur, Julie M. ...
  http://www.pnas.org/content/115/35/E8315