Loading...
*  A SMALL GTP-BINDING PROTEIN DISSOCIATES FROM SYNAPTIC VESICLES DURING EXOCYTOSIS
Nickel W, Kipper N, Barthel A, Kahn RA, Fasshauer D, Soling HD., Ann. N. Y. Acad. Sci. 733(), 1994 PMID: 7978885 ... mutations in the sec4 or ypt1 genes encoding small GTP-binding proteins inhibit constitutive membrane flow at the plasma ... Study of rab6, a ras-like GTP-binding protein associated with the Golgi complex.. Goud B, Yang C, Roa M, Martinez O, Mayau V., ... Study of rab6, a ras-like GTP-binding protein associated with the Golgi complex.. Goud B, Yang C, Roa M, Martinez O, Slepnev V ...
  https://pub.uni-bielefeld.de/publication/2374443
*  RGL3 (ral guanine nucleotide dissociation stimulator like 3)
RA_dom Ras-like_Gua-exchang_fac_N Ras_G-nucl-exch_fac_CS Ras_GEF_dom RASGEF_cat_dom RGL3 Ubiquitin-rel_dom ... Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to How to ... ENSG00000205517 [Gene_View]. Ensembl hg38 (Hinxton). ENSG00000205517 [Gene_View] chr19:11394056-11419342 [Contig_View] RGL3 [ ... Home Genes Leukemias Solid Tumors Cancer-Prone Deep Insight Case Reports Journals Portal Teaching X Y 1 2 3 4 5 6 7 8 9 10 11 ...
  http://atlasgeneticsoncology.org/Genes/GC_RGL3.html
*  Rasgrf2 MGI Mouse Gene Detail - MGI:109137 - RAS protein-specific guanine nucleotide-releasing factor 2
IPR001895 Ras guanine-nucleotide exchange factors catalytic domain. IPR000651 Ras-like guanine nucleotide exchange factor, N- ... IPR019804 Ras guanine-nucleotide exchange factor, conserved site. IPR023578 Ras guanine nucleotide exchange factor domain ... Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc ... VEGA Gene Model , MGI Sequence Detail. 251257. C57BL/6J. ± kb. transcript. OTTMUST00000086461. VEGA , MGI Sequence Detail. 5797 ...
  http://www.informatics.jax.org/marker/MGI:109137
*  Plus it
Distinct requirements for Ras oncogenesis in human versus mouse cells. Genes Dev 2002;16:2045-57. ... We analyzed MCP110 activity in NIH3T3 cells transformed by constitutively active H-Ras(G12V), K-Ras(G12V), and N-Ras(G12D). For ... Loss of transgelin in breast and colon tumors and in RIE-1 cells by Ras deregulation of gene expression through Raf-independent ... Selective action of MCP110 and paclitaxel in Ras versus Raf-transformed cells. A, NIH3T3-K-Ras(G12V) cells were stained with ...
  http://mct.aacrjournals.org/content/6/3/898
*  RAS type GTPase family (RAS) Gene Family | HUGO Gene Nomenclature Committee
muscle RAS oncogene homolog. M-RAs, R-RAS3, RRAS3. 3q22.3. NKIRAS1 NFKB inhibitor interacting Ras like 1. KBRAS1, kappaB-Ras1. ... RAS type family: The RAS family is a subset of the RAS small GTPase superfamily. The family includes the proto-oncogenes HRAS, ... RAP1A, member of RAS oncogene family. KREV-1, SMGP21. 1p13.2. RAP1B RAP1B, member of RAS oncogene family. K-REV, RAL1B, ... NFKB inhibitor interacting Ras like 2. KBRAS2, DKFZP434N1526, kappaB-Ras2. 17q21.2. NRAS NRAS proto-oncogene, GTPase. N-ras. ...
  https://www.genenames.org/cgi-bin/genefamilies/set/389
*  The Ras Gene and Cancer
Now one ras gene and protein all by itself would be interesting, but it turns out that there's a whole family of ras genes and ... But if both ras genes are knocked out, the yeast cells cannot multiply, and they die. Astonishingly, if a human ras gene is ... Moreover, the ras gene occurs in virtually all living things. For example, yeast cells also have two ras genes. If either one ... into a gene that would cause tumors. So there were two different ways in which the ras gene turned up. First, as a rat gene in ...
  http://www.accessexcellence.org/RC/AB/IWT/Ras_Gene_and_Cancer.html
*  ATCC Cell Lines by RAS Gene Mutation Page 1
Mutant RAS has been identified in pancreas, colon, thyroid, bladder and ovarian cancers and is predictive of a very poor ... RAS * HL-60 (ATCC® CCL-240™) ATCC® Number: CCL-240™ Organism: Homo sapiens, human ...
  https://www.atcc.org/Products/Cells_and_Microorganisms/By_Disease__Model/Cancer/Tumor_Cell_Panels/Cell_lines_by_genetic_mutation/RAS.aspx?dsNav=N:4294955978
*  ATCC Cell Lines by RAS Gene Mutation Page 1
Mutant RAS has been identified in pancreas, colon, thyroid, bladder and ovarian cancers and is predictive of a very poor ... RAS * RAS Genetic Alteration Cell Panel (ATCC® TCP-1031™) ATCC® Number: TCP-1031™ Organism: Homo sapiens, human ... Applications: This panel is useful for RAS pathway research and for anti-cancer drug discovery. ...
  https://www.atcc.org/en/Products/Cells_and_Microorganisms/By_Disease__Model/Cancer/Tumor_Cell_Panels/Cell_lines_by_genetic_mutation/RAS.aspx?dsNav=Up:Page_Product_Listing,Nrc:id-1000506-dynrank-disabled&hasShowAll=1000506%7C
*  ATCC Cell Lines by RAS Gene Mutation Page 5
Mutant RAS has been identified in pancreas, colon, thyroid, bladder and ovarian cancers and is predictive of a very poor ... RAS * AML-193 (ATCC® CRL-9589™) ATCC® Number: CRL-9589™ Organism: Homo sapiens, human ...
  https://www.atcc.org/Products/Cells_and_Microorganisms/By_Disease__Model/Cancer/Tumor_Cell_Panels/Cell_lines_by_genetic_mutation/RAS.aspx?dsNav=N:4294776519
*  NSCLC K-RAS gene mutation
Cancer Tutor Forum › Cancer Types › Lung Cancer › NSCLC K-RAS gene mutation ... Copper, genes, cancer. Articles. Recent research is pointing toward a correlation of higher tissue levels of copper in some ...
  https://www.cancertutor.com/discussions/nsclc-k-ras-gene-mutation/
*  ras - Ras - Anguilla anguilla (European freshwater eel) - ras gene & protein
Gene namesi. Name:rasImported. ,p>Information which has been imported from another database using automatic procedures.,/p> ,p ... tr,Q1WKM1,Q1WKM1_ANGAN Ras OS=Anguilla anguilla OX=7936 GN=ras PE=2 SV=1 ... RasImported. ,p>Information which has been imported from another database using automatic procedures.,/p> ,p>,a href="/manual/ ... p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source ...
  https://www.uniprot.org/uniprot/Q1WKM1
*  Ras Gene Causes Cancer Via Different Pathways in Humans vs. Mice
15, 2002, issue of Genes and Development. The Duke researchers decided to study oncogenic Ras, one of the first genes found to ... then traced how the protein produced by the Ras gene promoted cells to transform. As expected, Ras exerted its malignant ... While studying the Ras, gene, Duke researchers unexpectedly found that it activates an obscure group of proteins in humans, but ... Researchers at the Duke Comprehensive Cancer Center have found that a known cancer-causing gene, Ras, may exert its influence ...
  http://www.innovations-report.com/html/reports/medicine-health/report-12088.html
*  Gender Specific Association of RAS Gene Polymorphism with Essential Hypertension: A Case-Control Study
... Kh. Dhanachandra Singh, ... Supplementary Table 1: Details of the oligonucleotides for amplification and screening for four RAS polymorphisms using allele ...
  https://www.hindawi.com/journals/bmri/2014/538053/sup/
*  The Superfamily of ras-Related Genes | SpringerLink
... cell transformation appeared a vast amount of additional information has been generated which emphasizes the importance of ras- ... since the earliest results on the linkage between ras activation and ... Ras-related genes appear to be central to the mechanism of transformation by other oncogenes and therefore constitute a focal ... Prenylation of ras and ras-Related Proteins J. F. Hancock, K. Cadwallader, A. I. Magee, C. Newman, T. Giannakouros, E. Fawell ...
  https://link.springer.com/book/10.1007%2F978-1-4684-6018-6
*  C h ras genes Dictionary Definition and More from Dictionary.net
... ras, Ha- ras, rasH) and Kirsten ( K- ras, Ki- ras, rasK) murine sarcoma viruses. Ras genes are widely conserved among animal ... ras genes have been detected in human, avian, murine, and non- vertebrate genomes. The closely related N- ras gene has been ... Definitions of c H ras Genes. * Family of retrovirus- associated DNA sequences ( ras) originally isolated from Harvey ( H- ... previousC fragment endorphin next C h ras proto oncogenes C h ras genes. ...
  http://www.dictionary.net/c%20h%20ras%20genes
*  Alterations of C-Ha-ras Gene are Associated with c -myc Activation in Human Cervical Cancers | SpringerLink
Alterations of C-Ha-ras Gene are Associated with c-myc Activation in Human Cervical Cancers. In: Spandidos D. (eds) ras ... Barbacid, M., 1987, ras genes, Ann. Rev. Biochem., 56:779.PubMedCrossRefGoogle Scholar ... Riou, G., Barrois, M., Sheng, Z.M., Duvillard, P., and Lhomme, C., 1988, Somatic deletions and mutations of c-Ha-ras gene in ... Balmain, A., Ramsden, M., Bowden, G.T. and Smith, J., 1984, Activation of the mouse cellular Harvey-ras gene in chemically ...
  https://link.springer.com/chapter/10.1007/978-1-4757-1235-3_7
*  DIGITAL.CSIC: Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes
Twenty-one out of 22 carcinmas of the exocrine pancreas contained c-K-ras genes with mutations at codon 12. In seven cases ... Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes. ... c-K-ras genes in human pancreatic carcinomas. We used frozen tumor specimens and single 5 μm sections from formalin-fixed, ... Using in vitro gene amplification by the polymerase chain reaction (PCR) and mutation detection by the RNAase A mismatch ...
  http://digital.csic.es/handle/10261/32452
*  RAS genes in colorectal carcinoma: pathogenesis, testing guidelines and treatment implications | Journal of Clinical Pathology
The RAS family is among the most commonly mutated genes in all human malignancies including colon cancer. In normal cells, RAS ... get RAS mutation testing since only those with wildtype-RAS genes benefit from such treatment. Despite decades of research, ... RAS mutations, as supported by several studies including animal models, have a role in the development and progression of ... RAS isoproteins have great morphological similarities, but despite that, they are thought to have different functions in ...
  https://jcp.bmj.com/content/early/2018/11/16/jclinpath-2018-205471
*  Activation of VEGF and Ras genes in gastric mucosa during angiogenic response to ethanol injury | Gastrointestinal and Liver...
The decreased expression of total Ras protein (which includes H-Ras and N-Ras, as well as Ki-Ras) at these time points, ... Activation of VEGF and Ras genes in gastric mucosa during angiogenic response to ethanol injury. Michael K. Jones, Rabiha M. ... The present study also demonstrates for the first time that ethanol-induced injury to the gastric mucosa activates ras gene ... 1996) Increases in Ki-ras and ornithine decarboxylase gene expression in rat pancreas after caerulein-induced pancreatitis. ...
  http://ajpgi.physiology.org/content/276/6/G1345
*  Mariano Barbacid - Wikipedia
Ras genes.» Annu Rev Biochem 1987; 56: 779-827. Klein R, Jing SQ, Nanduri V, O'Rourke E, Barbacid M. The trk proto-oncogene ... "Ras genes." (1987). "The TRK proto-oncogene encodes a receptor for nerve growth-factor." (1991). "trkC, a new member of the trk ... Zarbl H, Sukumar S, Arthur AV, Martin-Zanca D, Barbacid M. «Direct mutagenesis of HA-RAS-1 oncogenes by N-Nitroso-N-Methylurea ... eventually discovering that such oncogene was the mutation of an allele of the Ras subfamily, as well as its activation ...
  https://en.wikipedia.org/wiki/Mariano_Barbacid
*  SOS1 - Wikipedia
Son of sevenless homolog 1 is a protein that in humans is encoded by the SOS1 gene. RAS genes (e.g., MIM 190020) encode ... Hu Q, Milfay D, Williams LT (March 1995). "Binding of NCK to SOS and activation of ras-dependent gene expression". Mol. Cell. ... Hu Q, Milfay D, Williams LT (1995). "Binding of NCK to SOS and activation of ras-dependent gene expression". Mol. Cell. Biol. ... cerevisiae CDC25 gene product. Genetic analysis indicated that CDC25 is essential for activation of RAS proteins. In Drosophila ...
  https://en.wikipedia.org/wiki/SOS1
*  Parkes Weber syndrome - Wikipedia
"RASA1 gene RAS p21 protein activator 1". "RASA1 RAS p21 protein activator 1". "RASA1 gene RAS p21 protein activator 1". ... RASA1 gene is responsible for making p120-RasGAP protein. This protein regulates the RAS/MAPK signaling pathway. RAS/MAPK ... This means that one copy of the damaged or altered gene is sufficient to elicit PWS disorder. In most cases, PWS can occur in ... Some cases of PWS are a result of mutations on the RASA1 gene which is located on chromosome 5 at position 14.3. This mutation ...
  https://en.wikipedia.org/wiki/Parkes_Weber_syndrome
*  Karen Vousden - Wikipedia
subscription required) Vousden, K. H.; Marshall, C. J. (1984). "Three different activated ras genes in mouse tumours; evidence ... Nakano, K; Vousden, KH (2001). "PUMA, a novel proapoptotic gene, is induced by p53". Mol Cell. 7: 683-694. doi:10.1016/S1097- ... Nakano, K.; Vousden, K. H. (2001). "PUMA, a Novel Proapoptotic Gene, is Induced by p53". Molecular Cell. 7 (3): 683-694. doi: ... Vousden, Karen (1982). Use of suppressor gene mutations to study transfer RNA redundancy in Coprinus (PhD thesis). Queen Mary ...
  https://en.wikipedia.org/wiki/Karen_Vousden
*  RASA4B - Wikipedia
RAS p21 protein activator 4B is a protein that in humans is encoded by the RASA4B gene. GRCh38: Ensembl release 89: ... ENSG00000170667 - Ensembl, May 2017 "Human PubMed Reference:". "Entrez Gene: RAS p21 protein activator 4B". Retrieved 2016-10- ...
  https://en.wikipedia.org/wiki/RASA4B