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*  Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer - Wikipedia
The Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer is a free access database devoted to chromosomes, ... A recent review noted that "It was first published in 1983 as a book named "The Catalog of Chromosome Aberrations in Cancer", ... in Oncology and Haematology COSMIC cancer database Ensembl genome database project Entrez Gene GenBank Gene Wiki HUGO Gene ... The information is organized into sub-databases: The "Cases Quick Searcher" lists cytogenetic aberrations in individual cancer ...
  https://en.wikipedia.org/wiki/Mitelman_Database_of_Chromosome_Aberrations_and_Gene_Fusions_in_Cancer
*  Radiation Flashcards by Amanda Romeu | Brainscape
Gene mutations, chromosome aberrations 22 What occurs when a radiation injury effects blood forming tissues? ... Can effect Ca homeostasis, chromosome damage/RNA transcription, cell response to hormones and enzymes and NTs, cellular immune ...
  https://www.brainscape.com/flashcards/radiation-3580277/packs/5466419
*  Association between myeloperoxidase G-463A polymorphism and lung cancer risk | SpringerLink
Polymorphisms in DNA repair genes, chromosome aberrations, and lung cancer. Environ Mol Mutagen. 2004;44:74-82.PubMedCrossRef ... Combined effect of mpo, gstm1 and gstt1 polymorphisms on chromosome aberrations and lung cancer risk. Int J Hyg Environ Health ... Phase i metabolic genes and risk of lung cancer: multiple polymorphisms and mrna expression. PLoS One. 2009;4:e5652. ... Variation in the promoter region of the myeloperoxidase gene is not directly related to lung cancer risk among male smokers in ...
  https://link.springer.com/article/10.1007/s13277-013-1067-6
*  Altered expression of LINC-ROR in cancer cell lines and tissues | SpringerLink
Mitelman database of chromosome aberrations and gene fusions in cancer. 2015. http://cgap.nci.nih.gov/Chromosomes/Mitelman. ... Cai T, Nesi G, Dal Canto M, Mondaini N, Piazzini M, Bartoletti R. Prognostic role of loss of heterozygosity on chromosome 18 in ... Long noncoding RNAs: emerging stars in gene regulation. Epigenetics and human disease. ChemMedChem. 2014. doi: 10.1002/cmdc. ... Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression. Proc Natl ...
  https://link.springer.com/article/10.1007/s13277-015-3933-x
*  Plus it
DNA repair gene polymorphisms in relation to chromosome aberration frequencies in retired radiation workers. MutatRes 2005;570: ... Polymorphisms in DNA repair genes, chromosome aberrations, and lung cancer. Environ Mol Mutagen 2004;44:74-82. ... Genetic polymorphisms and possible gene-gene interactions in metabolic and DNA repair genes: Effects on DNA damage. Mutation ... Effect of XPD/ERCC2 polymorphisms on chromosome aberration frequencies in smokers and on sensitivity to the mutagenic tobacco- ...
  http://cebp.aacrjournals.org/content/19/12/3055
*  Organizing knowledge to enable personalization of medicine in cancer | Genome Biology | Full Text
Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer. [], [http://cgap.nci.nih.gov/Chromosomes/Mitelman]. ... Genomic events and the genes or pathways that they affect must be placed in the context of drug-gene or drug-variant ... Good BM, Clarke EL, de Alfaro L, Su AI: The Gene Wiki in 2011: community intelligence applied to human gene annotation. Nucleic ... the Gene Ontology [17], and drug-gene databases such as DGIdb [18]. Similarly, a subset of clinical associations for cancer ...
  https://genomebiology.biomedcentral.com/articles/10.1186/s13059-014-0438-7
*  rs1042522 - SNPedia
PMID 20512840] Association between TP53 gene ARG72PRO polymorphism and chromosome aberrations in human cancers ... MDM2 gene SNP309 T/G and p53 gene SNP72 G/C do not influence diffuse large B-cell non-Hodgkin lymphoma onset or survival in ... How Contemporary Human Reproductive Behaviors Influence the Role of Fertility-Related Genes: The Example of the P53 Gene ... Gene TP53 CLNDBN not specified CODON 72 POLYMORPHISM, (rs1042522) not provided Hereditary cancer-predisposing syndrome Li- ...
  https://snpedia.com/index.php/Rs1042522
*  Dendritic cell fate is determined by BCL11A | PNAS
2004) Fusion genes and rearranged genes as a linear function of chromosome aberrations in cancer. Nat Genet 36(4):331-334. ... A target gene was defined by a binding site occurring within 50 kb upstream through the intron of that gene. Analysis of the ... 2004) A gene atlas of the mouse and human protein-encoding transcriptomes. Proc Natl Acad Sci USA 101(16):6062-6067. ... 2013) The BCL11A transcription factor directly activates RAG gene expression and V(D)J recombination. Mol Cell Biol 33(9):1768- ...
  http://www.pnas.org/content/111/11/E998.long
*  General Aspects of Colorectal Cancer
F. Mitelman, B. Johansson, and F. Mertens, Eds., Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer, 2012, ... Genes Chromosomes and Cancer, vol. 15, no. 4, pp. 234-245, 1996. View at Publisher · View at Google Scholar · View at Scopus ... Genes Chromosomes and Cancer, vol. 15, no. 4, pp. 234-245, 1996. View at Publisher · View at Google Scholar · View at Scopus ... Genes Chromosomes and Cancer, vol. 34, no. 3, pp. 276-284, 2002. View at Publisher · View at Google Scholar · View at Scopus ...
  https://www.hindawi.com/journals/isrn/2012/139268/ref/
*  ASMscience | DNA Polymorphisms in Gat
... in DNA repair and/or damage response genes and a cancer predisposition. Evidence documenting the impact of a polymorphism on ... Predisposing genes and increased chromosome aberrations in lung cancer cigarette smokers. Mutat. Res. 379:53-59.. ... Repair-related genes mapping in close proximity to the XPC gene on human chromosome 3p25.1-25.3. ... Repair-related genes mapping in close proximity to the XPC gene on human chromosome 3p25.1-25.3. ...
  http://www.asmscience.org/content/book/10.1128/9781555816704.ch30
*  Booktopia - Genetic Variants and Strains of the Laboratory Mouse by Mary F. Lyon, 9780198548690. Buy this book online.
Three very important chapters give the latest rules for nomenclature of genes, inbred strains, and chromosome aberrations. ... There are catalogues of known chromosome aberrations, of inbred strains, and of wild-derived strains. Valuable tables give ... 1: Rules and guidelines for gene nomenclature 2: Catalog of mutant genes and polymorphic loci 3: Retroviral and cancer-related ... Rules for nomenclature of chromosome anomalies 11: Standard normal chromosomes 12: Chromosomal variants 13: Maps of chromosomal ...
  https://www.booktopia.com.au/genetic-variants-and-strains-of-the-laboratory-mouse-mary-f-lyon/prod9780198548690.html
*  Rhabdomyosarcoma | Cancer Genetics Web
For a much more extensive list see the Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer. ... Genes Chromosomes Cancer. 2016; 55(1):3-15 [PubMed] Related Publications Rhabdomyosarcoma (RMS) is the most common soft tissue ... Many recurrent chromosome translocations in cancer result in the generation of fusion genes that are directly implicated in the ... Mutated Genes and Abnormal Protein Expression (19). Clicking on the Gene or Topic will take you to a separate more detailed ...
  http://www.cancerindex.org/geneweb/X2002.htm
*  Osteosarcoma | Cancer Genetics Web
For a much more extensive list see the Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer. ... Mutated Genes and Abnormal Protein Expression. Recurrent Chromosome Abnormalities. Dseases that predispose to osteosarcoma. ... Mutated Genes and Abnormal Protein Expression (48). Clicking on the Gene or Topic will take you to a separate more detailed ... Evidence for a novel osteosarcoma tumor-suppressor gene in the chromosome 18 region genetically linked with Paget disease of ...
  http://www.cancerindex.org/geneweb/X0203.htm
*  Chromosome Y | Cancer Genetics Web
For a much more extensive list see the Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer. ... Selected list of common recurrent structural abnormalities - Chromosome Y:. Abnormality. Type. Gene(s). Chromosome Y Loss in ... Genes Linked with Cancer (2). Click on the gene name for detailed information. Type in the Search box e.g. 'germline' or ' ... Breast Cancer' to search within Chromosome Y; or Sort by clicking on a column heading e.g. 'Gene'. ...
  http://www.cancerindex.org/geneweb/clinkc24.htm
*  B-cell maturation antigen - Wikipedia
"Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer". "Atlas of Genetics and Cytogenetics in Oncology and ... "A new gene, BCM, on chromosome 16 is fused to the interleukin 2 gene by a t(4;16)(q26;p13) translocation in a malignant T cell ... Genes and Immunity. 2 (5): 276-9. doi:10.1038/sj.gene.6363770. PMID 11528522. Novak AJ, Darce JR, Arendt BK, Harder B, ... "Entrez Gene: TNFRSF17 tumor necrosis factor receptor superfamily, member 17". Liu Y, Hong X, Kappler J, Jiang L, Zhang R, Xu L ...
  https://en.wikipedia.org/wiki/B-cell_maturation_antigen
*  James Huff, Ph.D. - Retired
... gene mutations, chromosome aberrations, aneuploidy, sister chromatid exchanges, and unscheduled DNA synthesis in Syrian hamster ...
  https://www.niehs.nih.gov/about/od/deputy/huff/
*  XRCC1 Polymorphisms and Cancer Risk: A Meta-analysis of 38 Case-Control Studies | Cancer Epidemiology, Biomarkers & Prevention
Harms C, Salama SA, Sierra-Torres CH, Cajas-Salazar N, Au W-W. Polymorphisms in DNA repair genes, chromosome aberrations, and ... To further evaluate gene-to-gene and gene-to-environment interactions on XRCC1 polymorphisms and cancer risk, a single larger ... However, lacking of the original data of the meta-analysis limited our further evaluation of potential gene-to-gene and gene-to ... Association of the DNA repair gene XPD Asp312Asn polymorphism with p53 gene mutations in tobacco-related non-small cell lung ...
  http://cebp.aacrjournals.org/content/14/7/1810.long
*  Mitelman Help
... and chromosomal changes and/or gene rearrangements resulting from chromosome aberrations. Information on "Abnormality", " ... Enter gene designation to find rearranged gene, e.g., "BCR". *Enter gene designations separated by slash "/" to find gene ... Gene: Provides information on rearranged genes located in breakpoints of acquired cytogenetic aberrations. *Molecular ... ring chromosomes (r), and double minutes (dmin). *Gene symbols are in accordance with the most recent Guidelines for Human Gene ...
  https://cgap.nci.nih.gov/Chromosomes/Help
*  Molecular Analysis of Gene Rearrangements and Mutations in Acute Leukemias and Myeloid Neoplasms - Current Protocols
Standardized RT‐PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal ... Cooperating gene mutations in acute myeloid leukemia: A review of the literature. Leukemia 22:915‐931. doi: 10.1038/leu.2008.19 ... Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype. Blood ... Molecular Analysis of Gene Rearrangements and Mutations in Acute Leukemias and Myeloid Neoplasms. ...
  http://www.currentprotocols.com/WileyCDA/CPUnit/refId-hg1004.html?quicktabs_cp=toc
*  Chromosome abnormality - Wikipedia
"Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer". Archived from the original on 2016-05-29.. ... A chromosome abnormality, disorder, anomaly, aberration, or mutation is a missing, extra, or irregular portion of chromosomal ... Chromosome mutation was formerly used in a strict sense to mean a change in a chromosomal segment, involving more than one gene ... Genes on chromosome 21 that specifically contribute to the various symptoms of Down syndrome are now being identified. The ...
  https://en.wikipedia.org/wiki/Chromosome_abnormalities
*  Oncolytic Paramyxoviruses: Mechanism of Action, Preclinical and Clinical Studies | SpringerLink
The genes of interferons and interferonrelated factors: Localization and relationships with chromosome aberrations in cancer. ... Newcastle disease virus: A promising vector for viral therapy, immune therapy, and gene therapy of cancer. Meth. Mol. Biol. 542 ... Fusogenic membrane glycoproteins as a novel class of genes for the local and immune-mediated control of tumor growth. Cancer ... A new Sendai virus vector deficient in the matrix gene does not form virus particles and shows extensive cell-tocell spreading ...
  https://link.springer.com/article/10.1134/S002689331803010X
*  DCB - DNA and Chromosome Aberrations Research - National Cancer Institute
Research on DNA and chromosome aberrations focuses on cancer genetics and epigenetics. Topics include regulation of gene ... Gene Regulation and Epigenetics. Gene regulations and epigenetics research focuses on the aberrant expression of cellular genes ... Genes activated or repressed by radiation and chemical exposure. An emerging area of interest is the role that chromosome ... Research in this area is supported and directed by the DNA and Chromosome Aberrations Branch (DCAB). ...
  https://www.cancer.gov/about-nci/organization/dcb/research-portfolio/dcar
*  Embryogenetics of Cleft Lip and Palate | SpringerLink
Among the possible causes of clefts are single gene disorders, chromosome aberrations, teratogen exposure, and many as yet ... Honkura T, Ogasawara J, Yamada T, Morishita S (2002) The Gene Resource Locator: gene locus maps for transcriptome analysis. ... Evidence of gene-environment interaction for the RUNX2 gene and environmental tobacco smoke in controlling the risk of cleft ... De Robertis EM, Morita EA, Cho KW (1991) Gradient fields and homeobox genes. Development 112:669-678PubMedGoogle Scholar ...
  https://link.springer.com/chapter/10.1007/978-3-642-30770-6_1
*  A high complex karyotype involving eleven chromosomes including three novel chromosomal aberrations and monoallelic loss of...
Mitelman database of chromosome aberrations and gene fusions in cancer. 2015. http://cgap.nci.nih.gov/Chromosomes/Mitelman [ ... Stochastic cancer progression driven by nonclonal chromosome aberrations. J Cell Physiol. 2006;208:461-72.View ArticlePubMed ... Other common cytogenetic aberrations are +7, +18, and abnormalities and gene rearrangements in 3q27-28 (BCL6), 6q23-26, and 17p ... The normal chromosomes (#) are depicted in the first column on the left side and the derivative of the other chromosomes on the ...
  https://molecularcytogenetics.biomedcentral.com/articles/10.1186/s13039-016-0300-6
*  PPT - Ch7. Chromosome Mutation Variation in Number and Arrangement PowerPoint Presentation - ID:4099250
Although most members of diploid species normally contain precisely two haploid chromosome sets, many known cases vary from ... Taken together, such changes are called chromosome mutations or chromosome aberrations, to distinguish them from gene mutations ... Chapter 7: Chromosome Mutations -. *chromosome mutations/aberrations. variation in chromosome number: *aneuploidy *euploidy * ... sex chromosomes. determine the sex of the individual in humans: x and y chromosomes x chromosome larger than y chromosome. all ...
  https://www.slideserve.com/love/ch7-chromosome-mutation-variation-in-number-and-arrangement