Histone H3K9/14ac (Acetyl H3K9/14) Polyclonal Antibody | EpiGentek
al. (April 2017). Prenatal Exposure to a Maternal High-Fat Diet Affects Histone Modification of Cardiometabolic Genes in ... Gene Expression & Silencing. DNA Damage & Repair. Histone Phosphorylation. SUMOylation. Next-Generation Sequencing Products & ...http://www.epigentek.com/catalog/histone-h3k914ac-acetyl-h3k914-polyclonal-antibody-p-1204.html
ChromaFlash Chromatin Extraction Kit | EpiGentek
al. (April 2017). Prenatal Exposure to a Maternal High-Fat Diet Affects Histone Modification of Cardiometabolic Genes in ... Gene Expression & Silencing. DNA Damage & Repair. Histone Phosphorylation. SUMOylation. Next-Generation Sequencing Products & ... With ChIP, the experimenter can determine if a specific protein binds to the specific sequences of a gene in living cells by ... For example, the measurement of the amount of methylated histone H3 at lysine 9 (meH3-K9) associated with a specific gene ...http://www.epigentek.com/catalog/chromaflash-chromatin-extraction-kit-p-2863.html
Programming of mouse obesity by maternal exposure to concentrated ambient fine particles | Particle and Fibre Toxicology | Full...
4o). In addition, we did not observe any significant effect of maternal exposure to CAP on the hypothalamic gene expression of ... findings together strongly suggest that ambient PM2.5 pollution is an environmental stressor that programs cardiometabolic ... Maternal exposure to CAP increases adiposity in adult offspring. To further document the effects of maternal exposure to CAP on ... Maternal exposure to CAP alters offspring birth weight and growth trajectory. To assess the long-term effects of maternal ...https://particleandfibretoxicology.biomedcentral.com/articles/10.1186/s12989-017-0201-9
Maternal effect - Wikipedia
Diet Exposure In Utero on the Obesogenic and Diabetogenic Traits Through Epigenetic Changes in Adiponectin and Leptin Gene ... "Maternal undernutrition and cardiometabolic disease: a Latin American perspective". BMC Medicine. 13: 41. doi:10.1186/s12916- ... Since these genes are expressed in the (maternal) nurse cells and not in the oocyte or fertilised embryo, the maternal genotype ... This is a maternal, not an adaptive maternal effect. In order to be an adaptive maternal effect, the mother's environment would ...https://en.wikipedia.org/wiki/Maternal_effect
Exposure to Maternal Diabetes in Utero and DNA Methylation Patterns in the Offspring
... which are known to be associated with cardiometabolic traits. Gene enrichment analysis of the top 84 genes, each with p,=0.005 ... Multiple candidate genes and the UPS were identified for future study as possible links between exposure to maternal ... on the impact of exposure to maternal diabetes ,italic,in utero,/italic, on VCAM-1 levels in the offspring. ... more definitively investigate the potential for mediation of the effect of exposure to maternal diabetes ,italic,in utero,/ ...https://www.infona.pl/resource/bwmeta1.element.-psjd-doi-10_2478_immun-2013-0001
Smoking Cessation News, Research
Epigenetic link found between prenatal exposure to maternal smoking and offspring's cardio-metabolic health According to new ... Lancaster professor aims to understand how genes affect smoking cessation The Canadian Institute of Health Research has awarded ... Teens more likely to pick up smoking after exposure from friends and family Teenagers whose mothers smoked during pregnancy, or ... Study evaluates second-hand marijuana smoke exposure among children In a study designed to evaluate second-hand marijuana smoke ...https://www.news-medical.net/?tag=/Smoking+Cessation
Prenatal Testosterone Exposure Decreases Aldosterone Production but Maintains Normal Plasma Volume and Increases Blood Pressure...
Prenatal effects of maternal smoking on daughters' smoking: nicotine or testosterone exposure? Am J Public Health. 1999;89:1377 ... Effect of prenatal testosterone (T) exposure on mRNA expression of major steroidogenic genes in adrenals of adult female rats. ... contributes to several features of the programmed cardiometabolic phenotype (i.e., hypertension, insulin resistance, ... Adrenal Steroidogenic and Angiotensin II Receptor Gene Expression. To address the effect of prenatal testosterone exposure on ...http://pubmedcentralcanada.ca/pmcc/articles/PMC5029475/
Glucocorticoid excess and the developmental origins of disease: two decades of testing the hypothesis--2012 Curt Richter Award...
... is associated with cardiometabolic disease and brain disorders in adulthood. The adaptive changes made by the fetus in response ... Prenatal Exposure Delayed Effects*. Stress, Physiological / physiology*. Stress, Psychological / physiopathology*. Grant ... Maternal-Fetal Exchange. Metabolic Syndrome X / embryology, etiology, physiopathology. Models, Biological*. Neuroendocrinology ... In a recent study we showed that alterations in DNA methylation at genes important in regulating cortisol levels, tissue ...http://www.biomedsearch.com/nih/Glucocorticoid-excess-developmental-origins-disease/22998948.html
Abstract MP59: Associations of Maternal Pre-pregnancy Body Mass Index and Gestational Weight Gain with Offspring Longitudinal...
Genotyping of mothers and offspring was carried out for 180 candidate genes related to cardio-metabolic outcomes. We created ... genetic propensity scores using a subset of 388 SNPs from 53 adiposity-related genes that were predictive of the exposures and ... Mapping genes underlying these associations with longitudinal change in BMI may potentially lead to targeted intervention ... Conclusions This study points to the strong relationship between maternal excess weight and weight gain in pregnancy with ...http://circ.ahajournals.org/content/127/Suppl_12/AMP59
Professor Philip Calder | Medicine | University of Southampton
... maternal fish and marine n-3 fatty acid intake, and marine n-3 fatty acid status in maternal and umbilical cord blood. American ... Miles, E. A., & Calder, P. C. (2017). Can early omega-3 fatty acid exposure reduce risk of childhood allergic disease? ... Calder, P. C., Grimble, R. F., & Howell, W. M. (2002). Gene polymorphisms, inflammatory diseases and cancer. Proceedings of the ... Innes, J., & Calder, P. (2018). The differential effects of eicosapentaenoic acid and docosahexaenoic acid on cardiometabolic ...https://www.southampton.ac.uk/medicine/about/staff/pcc.page
Scientists to focus on big data and genetics to identify risk factors for dementia - Medicalnewser.com
Epigenetic link found between prenatal exposure to maternal smoking and offspring's cardio-metabolic health. November 14, 2018 ... The genes associated with its etiology (APP, PSEN1, PSEN2) were discovered 30 years ago. "However, these Alzheimer genes also ... November 14, 2018 - Epigenetic link found between prenatal exposure to maternal smoking and offspring's cardio-metabolic health ... November 13, 2018 - Gene changes driving myopia reveal new focus for drug development. November 13, 2018 - $6 million grant to ...http://www.medicalnewser.com/2018/06/18/scientists-to-focus-on-big-data-and-genetics-to-identify-risk-factors-for-dementia.html
Journal.pone.0035907 | Malnutrition | Fetus
Black RE (2008) Maternal and child undernutrition: global and regional exposures and health consequences.who. et al. Am J Clin ... 2011) Epigenetic gene promoter methylation at birth is associated with child's later adiposity. 2001: systematic analysis of ... We further propose that survivors of kwashiorkor will have a differential and lesser risk of obesity and its cardio-metabolic ... 2008) Maternal and Child Undernutrition Study Group. Gluckman PD. Badaloo AV. 3. et al. Walker SP. Forrester T. Reid M. ...https://es.scribd.com/document/247908189/Journal-pone-0035907
Maternal obesity during pregnancy and premature mortality from cardiovascular event in adult offspring: follow-up of 1 323 275...
... primates have shown global and gene specific alterations in DNA methylation and histone modifications after maternal exposure ... Impact of maternal obesity on offspring obesity and cardiometabolic disease risk. Reproduction2010;140:387-98. ... Associations of maternal prepregnancy body mass index and gestational weight gain with adult offspring cardiometabolic risk ... The mean maternal BMI value in the data was 22.86. Therefore we took the maternal BMI value of 23 as the reference value and ...http://www.bmj.com/content/347/bmj.f4539%20
Altered thyroid hormone profile in offspring after exposure to high estradiol environment during the first trimester of...
Maternal high estradiol (E2) is a major characteristic of IVF-ET and lasts throughout the first trimester of pregnancy. The ... The maternal high E2 environment in the first trimester is correlated with increased risk of thyroid dysfunction. Frozen ET ... Levels of serum T3, FT3, T4, FT4, and TSH and levels of maternal E2 at different stages of the first trimester were examined. ... The aim of this study is to investigate whether the high E2 maternal environment in the first trimester increases the risk of ...https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-014-0240-0
ISNN2018 Abstract Submission
Expression of genes related to energy metabolism increase resting metabolic rate adjusted by weight in obese women. Bruno ... The effect of paternal and maternal high-fat high-sugar diet on the offspring. Helena César1, Esther Alves de Souza2, Giovana ... Alterations in DNA methylation as a quantitative measure of exposure of normal cells to dietary stilbenoids. Megan Beetch1, a, ... A nutrigenetics approach to study the impact of genetic and dietary factors on cardiometabolic traits: Findings from the ...http://umanitoba.ca/centres/rcffn/conferences/isnn2018/abstracts.html
JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
Medicine, Issue 44, mammary gland morphology, terminal end buds, mammary cancer, maternal dietary exposures, pregnancy, ... Thus, C. elegans provides a powerful platform with which to assess the impact of mutations, gene knockdown, and/or chemical ... Medicine, Issue 83, dried blood spots (DBS), Biomarkers, cardiometabolic risk, Inflammation, standard precautions, blood ... Exposure to alcohol during development can result in a constellation of morphological and behavioral abnormalities that are ...https://www.jove.com/visualize/abstract/23383038/increased-childhood-mortality-arsenic-drinking-water-matlab
Metabolomic profiling in blood from umbilical cords of low birth weight newborns | Journal of Translational Medicine | Full Text
Wolff GL, Kodell RL, Moore SR, Cooney CA: Maternal epigenetics and methyl supplements affect agouti gene expression in Avy/a ... in LBW children can be epigenetically programmed by intrauterine exposures that have the capacity to modify fetal genes through ... Finding discriminatory metabolites in umbilical cord blood plasma from LBW newborns with a higher risk to develop cardio-metabolic ... No differences were observed in maternal age, maternal BMI, pregnancy weight gain or type of delivery between the two groups. ...https://translational-medicine.biomedcentral.com/articles/10.1186/1479-5876-10-142
Seed Grants 2013 - University of Maryland, Baltimore
Maternal-infant immunization for protection against B. Pertussis. Marcela Pasetti (UMB School of Medicine, Center for Vaccine ... Gaucher disease (GD), the most frequent lipid storage disorder is caused by mutations in the glucocerebrosidase gene. Patients ... Though medical history and lifestyle are important risk factors for cardiometabolic diseases, it is also clear that ... The study brings together investigators with expertise in air pollution exposure modeling, and environmental, cardiovascular ...https://www.umaryland.edu/ord/resources-for-investigators/find-funding-opportunities/umb-umcp-seed-grant-program/seed-grants-2013/
Genomes and Genes, Research Grants, Publications, Scientific Experts, Articles from Journal RESEARCH, Research Topics about ... Genomes and Genes. *Nos2 products*B2 products*Agtr2 products*Adra2a products*HCN4 products*ADRB1 products*ADRB2 products*ACE ... Exposure, Epidemiology, and Risk Program, Harvard School of Public Health, Boston, Massachusetts 02215, USA. Am J Epidemiol 173 ... Stress and Subclinical Cardio-Metabolic Disease in Police: A Longitudinal Study. John M Violanti; Fiscal Year: 2013 ...https://www.labome.org/topics/physical/natural/biological/circulatory/cardiovascular/cardiovascular/hemodynamic/heart-rate-20007.html
Tulane University - Publications - Epidemiology
Zhao J, * Zhu Y, Xiong M. Genome-wide gene-gene interaction analysis for next-generation sequencing. Eur J Hum Genet 2015 Jul ... Adverse maternal and perinatal outcomes in adolescent pregnancies: The Global Network's Maternal Newborn Health Registry study ... Multiple cardiometabolic risk factors in the Southern Cone of Latin America: a population-based study in Argentina, Chile, and ... Morales, M.E, Derbes, R.S., Ade, C.M., Ortego, J., Stark, J., Deininger, P.L., and Roy-Engel, A.M. (2016). Heavy metal exposure ...http://www2.tulane.edu/publichealth/epi/publications.cfm
Publications in the DSHealth doctoral thesis series | Research | University of Helsinki
Systemic Exposure to Oral Infections - a Cardiometabolic Risk. 61/2017 Hanna Dyggve. Doberman Hepatitis - Role of Immunological ... Nicotine Dependence - Identifying the Contribution of Specific Genes. 43/2017 Marjaana Pussila. Cancer-preceding Gene ... Importance of Maternal Behaviour and Circulating Oxytocin for Successful Lactation in Sows -Effects of Prepartum Housing ... Gene Expression and Functional Studies on Psoriatic Epidermis. 61/2016 Kristina Malinovskaja-Gomez. Transdermal Iontophoresis ...https://www.helsinki.fi/en/research/doctoral-education/doctoral-schools-and-programmes/doctoral-school-in-health-sciences/publications-in-the-dshealth-doctoral-thesis-series
Genomes and Genes, Articles from Journal RESEARCH, Publications, Research Grants about chronic disease ... Genomes and Genes. *Tcra products*PRSS1 products*Ifng products*Sharpin products*Il4 products*Nos2 products*HLA-DQB1 products* ... Further, maternal vitamin D status during pregnancy is associated with chronic disease in offspring, and the prenatal period ... and cardiometabolic disease risk factor development in childhood and subsequent risk for adult onset chronic disease)... ...http://www.labome.org/topics/diseases/signs/pathologic/disease/chronic-disease-8607.html
Publications 2014 | Biocenter Oulu
Gagnon DD, Gagnon SS, Rintamäki H, Törmäkangas T, Puukka K, Herzig KH, Kyröläinen H. The effects of cold exposure on leukocytes ... Use of synteny to identify candidate genes underlying QTL controlling stomatal traits in faba bean (Vicia faba L.). Theor Appl ... How do changes in body mass index in infancy and childhood associate with cardiometabolic profile in adulthood? Findings from ... Maternal cigarette smoking during pregnancy predicts drug use via externalizing behavior in two community-based samples of ...http://www.oulu.fi/biocenter/publications-2014
CDC - Progestin-Only Contraceptives - USMEC - Reproductive Health
Healthy people 2020: maternal, infant, and child health objectives. Washington, DC: US Department of Health and Human Services ... Hormonal exposures and breast cancer in a sample of women with systemic lupus erythematosus. Rheumatology (Oxford) 2004;43:1178 ... Deterioration in cardiometabolic risk markers in obese women during depot medroxyprogesterone acetate use. Contraception 2012; ... Factor V Leiden, prothrombin gene mutation, and thrombosis risk in patients with antiphospholipid antibodies. J Rheumatol 2002; ...https://www.cdc.gov/reproductivehealth/contraception/mmwr/mec/appendixC.html
Electronic cigarettes and smoking cessation: an interview with Professor Peter Hajek
Epigenetic link found between prenatal exposure to maternal smoking and offspring's cardio-metabolic health ... Smoking genes do not trigger heavier drinking, shows research. Lancaster professor aims to understand how genes affect smoking ... Maternal smoking during pregnancy associated with increased risk of strabismus in offspring ...https://www.news-medical.net/news/20150205/Electronic-cigarettes-and-smoking-cessation-an-interview-with-Professor-Peter-Hajek.aspx