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*  Familial partial lipodystrophy | definition of familial partial lipodystrophy by Medical dictionary
The Biological Basis of Hutchinson-Gilford Syndrome (HGS): Relationship to Mutagens in the Lamin A/C Gene (LMNA) and to Other ... In 1998, researchers localized a human gene that caused familial partial lipodystrophy, called Dunnigan type (FPLD). ... Porcine LMNA is a positional candidate gene associated with growth and fat deposition ... related to the site of missense mutations in lamin A/C gene. ...
  https://medical-dictionary.thefreedictionary.com/familial+partial+lipodystrophy
*  btsR - Transcriptional regulatory protein BtsR - Escherichia coli (strain K12) - btsR gene & protein
... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 54. D → E: 2- ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 54. D → N: 10 ... help/gene_ontology' target='_top'>More...,/a>,/p>GO - Biological processi. *phosphorelay signal transduction system Source: ... Biological process. Transcription, Transcription regulation, Two-component regulatory system. Enzyme and pathway databases. ...
  http://www.uniprot.org/uniprot/P0AFT5
*  Cidea - Cell death activator CIDE-A - Mus musculus (Mouse) - Cidea gene & protein
Acts as a CEBPB coactivator in mammary epithelial cells to control the expression of a subset of CEBPB downstream target genes ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 23. K → A: ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 23. K → R: ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 24. K → A: ...
  http://www.uniprot.org/uniprot/O70302
*  KDM4B - Lysine-specific demethylase 4B - Homo sapiens (Human) - KDM4B gene & protein
... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 189 - 191. ... help/gene_ontology' target='_top'>More...,/a>,/p>GO - Biological processi. *histone H3-K36 demethylation Source: UniProtKB ,p> ... that can be generated from the same gene by a single or by the combination of up to four biological events (alternative ... GO (Gene Ontology) annotation. *. Nucleus. *Nucleus PROSITE-ProRule annotation. ,p>Manual validated information which has been ...
  http://www.uniprot.org/uniprot/O94953
*  Zbtb33 - Transcriptional regulator Kaiso - Mus musculus (Mouse) - Zbtb33 gene & protein
Contributes to the repression of target genes of the Wnt signaling pathway. May also activate transcription of a subset of ... target genes by the recruitment of CTNND2. Represses expression of MMP7 in conjunction with transcriptional corepressors ... N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 472. K → A: ...
  https://www.uniprot.org/uniprot/Q8BN78
*  Eif2ak3 - Eukaryotic translation initiation factor 2-alpha kinase 3 precursor - Mus musculus (Mouse) - Eif2ak3 gene & protein
... and hence allowing ATF4-mediated reprogramming of amino acid biosynthetic gene expression to alleviate nutrient depletion ( ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 618. K → A: ... help/gene_ontology' target='_top'>More...,/a>,/p>GO - Biological processi. *activation of cysteine-type endopeptidase activity ... or inferences about a gene drawn from the phenotype of a mutation in a different gene.,/p> ,p>More information in the ,a href=" ...
  http://www.uniprot.org/uniprot/Q9Z2B5
*  YES1 - Tyrosine-protein kinase Yes - Homo sapiens (Human) - YES1 gene & protein
... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 426. Y → F: ... help/gene_ontology' target='_top'>More...,/a>,/p>GO - Biological processi. *cell differentiation Source: GO_Central ... "Distribution of c-yes-1 gene product in various cells and tissues.". Sugawara K., Sugawara I., Sukegawa J., Akatsuka T., ... ion channel binding Source: BHF-UCL ,p>Inferred from Physical Interaction,/p> ,p>Covers physical interactions between the gene ...
  http://www.uniprot.org/uniprot/P07947
*  YBX1 - Nuclease-sensitive element-binding protein 1 - Homo sapiens (Human) - YBX1 gene & protein
Regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced ... such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 102. S → A: ... help/gene_ontology' target='_top'>More...,/a>,/p>GO - Biological processi. *CRD-mediated mRNA stabilization Source: UniProtKB , ...
  https://www.uniprot.org/uniprot/P67809
*  Hnf4a - Hepatocyte nuclear factor 4-alpha - Rattus norvegicus (Rat) - Hnf4a gene & protein
Binds to DNA sites required for the transcription of alpha 1-antitrypsin, apolipoprotein CIII, transthyretin genes and HNF1- ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 142 - 143. SS ... help/gene_ontology' target='_top'>More...,/a>,/p>GO - Biological processi. *acyl-CoA metabolic process Source: RGD ,p>Inferred ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 142 - 143. SS ...
  http://www.uniprot.org/uniprot/P22449
*  STE20 - Serine/threonine-protein kinase STE20 - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) - STE20...
Needed for mating in haploid cells, induction of a mating-specific gene FUS1, induction of mating-specific morphologies, and ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 338. S → A: ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 345. H → A or ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 348. H → D: ...
  http://www.uniprot.org/uniprot/Q03497
*  Dapk3 - Death-associated protein kinase 3 - Mus musculus (Mouse) - Dapk3 gene & protein
... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 42. K → A: ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 294. A → D: ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 422. V → A: ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 429. V → A: ...
  http://www.uniprot.org/uniprot/O54784
*  NS - Non-structural protein 1 - Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) - NS gene & protein
... which normally triggers the antiviral transduction signal that leads to the activation of type I IFN genes by transcription ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 20. K → A: No ... Biological process. Eukaryotic host gene expression shutoff by virus, Host gene expression shutoff by virus, Host mRNA ... that can be generated from the same gene by a single or by the combination of up to four biological events (alternative ...
  https://www.uniprot.org/uniprot/P03496
*  MIOX - Inositol oxygenase - Homo sapiens (Human) - MIOX gene & protein
... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 127. K → S: ... Gene expression databases. Bgee dataBase for Gene Expression Evolution. More...Bgeei. ENSG00000100253 Expressed in 39 organ(s ... that can be generated from the same gene by a single or by the combination of up to four biological events (alternative ... based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.,p>,a href='/help/gene_centric_isoform_ ...
  https://www.uniprot.org/uniprot/Q9UGB7
*  Pik3c3 - Phosphatidylinositol 3-kinase catalytic subunit type 3 - Mus musculus (Mouse) - Pik3c3 gene & protein
... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 163. T → A: ... help/gene_ontology' target='_top'>More...,/a>,/p>GO - Biological processi. *autophagosome assembly Source: MGI ,p>Inferred from ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 165. S → A: ... that can be generated from the same gene by a single or by the combination of up to four biological events (alternative ...
  http://www.uniprot.org/uniprot/Q6PF93
*  Slc1a2 - Excitatory amino acid transporter 2 - Rattus norvegicus (Rat) - Slc1a2 gene & protein
... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 298. K → H or ... that can be generated from the same gene by a single or by the combination of up to four biological events (alternative ... based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.,p>,a href='/help/gene_centric_isoform_ ... p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of ...
  https://www.uniprot.org/uniprot/P31596
*  HIS7 - Imidazole glycerol phosphate synthase hisHF - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) -...
... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 239. R → A, H ... help/gene_ontology' target='_top'>More...,/a>,/p>GO - Biological processi. *glutamine metabolic process Source: UniProtKB-KW ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 258. K → A: ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 258. K → R: ...
  http://www.uniprot.org/uniprot/P33734
*  Arhgap35 - Rho GTPase-activating protein 35 - Mus musculus (Mouse) - Arhgap35 gene & protein
... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 1396. L → Q ... Gene expression databases. Bgee dataBase for Gene Expression Evolution. More...Bgeei. ENSMUSG00000058230 Expressed in 285 organ ... GO - Biological processi. *axonal fasciculation Source: UniProtKB ,p>Inferred from Mutant Phenotype,/p> ,p>Describes ... Gene expression databases. Bgeei. ENSMUSG00000058230 Expressed in 285 organ(s), highest expression level in ear vesicle. ...
  https://www.uniprot.org/uniprot/Q91YM2
*  INSIG2 - Insulin-induced gene 2 protein - Homo sapiens (Human) - INSIG2 gene & protein
... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 149. D → A: ... help/gene_ontology' target='_top'>More...,/a>,/p>GO - Biological processi. *cholesterol biosynthetic process Source: Ensembl ... GO (Gene Ontology) annotation. *. Endoplasmic reticulum. *Endoplasmic reticulum membrane 1 Publication. ,p>Manually curated ... Biological process. Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism. Enzyme and pathway ...
  http://www.uniprot.org/uniprot/Q9Y5U4
*  OGG1 - N-glycosylase/DNA lyase - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) - OGG1 gene & protein
... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 241. K → Q: ... help/gene_ontology' target='_top'>More...,/a>,/p>GO - Biological processi. *base-excision repair, AP site formation Source: SGD ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 241. K → R: ... or inferences about a gene drawn from the phenotype of a mutation in a different gene.,/p> ,p>More information in the ,a href=" ...
  http://www.uniprot.org/uniprot/P53397
*  INTS11 - Integrator complex subunit 11 - Homo sapiens (Human) - INTS11 gene & protein
... and is recruited to the U1 and U2 snRNAs genes. Mediates the snRNAs 3' cleavage. Mediates recruitment of cytoplasmic dynein to ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 203. E → Q: ... help/gene_ontology' target='_top'>More...,/a>,/p>GO - Biological processi. *snRNA processing Source: BHF-UCL ,p>Inferred from ... that can be generated from the same gene by a single or by the combination of up to four biological events (alternative ...
  http://www.uniprot.org/uniprot/Q5TA45
*  ileS - Isoleucine--tRNA ligase - Escherichia coli (strain K12) - ileS gene & protein
... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 97. C → S: No ... help/gene_ontology' target='_top'>More...,/a>,/p>GO - Biological processi. *isoleucyl-tRNA aminoacylation Source: EcoCyc ,p> ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 94. G → R: ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 102. I → N: ...
  http://www.uniprot.org/uniprot/P00956
*  hinT - Purine nucleoside phosphoramidase - Escherichia coli (strain K12) - hinT gene & protein
... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 101. H → A or ... GO - Biological processi. *D-alanine catabolic process Source: EcoCyc ,p>Inferred from Mutant Phenotype,/p> ,p>Describes ... Cells lacking this gene fail to grow on both D and L isomers of alanine due to a defect in DadA dehydrogenase activity, ... This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a ...
  https://www.uniprot.org/uniprot/P0ACE7
*  EIF4EBP3 - Eukaryotic translation initiation factor 4E-binding protein 3 - Homo sapiens (Human) - EIF4EBP3 gene & protein
... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 40. Y → A: ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 45. L → A: ... help/gene_ontology' target='_top'>More...,/a>,/p>GO - Biological processi. *negative regulation of translational initiation ... p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of ...
  http://www.uniprot.org/uniprot/O60516
*  thiI - tRNA sulfurtransferase - Escherichia coli (strain K12) - thiI gene & protein
... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 108. C → A: ... help/gene_ontology' target='_top'>More...,/a>,/p>GO - Biological processi. *thiamine biosynthetic process Source: EcoCyc ,p> ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 189. D → A: ... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 202. C → A: ...
  http://www.uniprot.org/uniprot/P77718
*  NEDD8 - NEDD8 precursor - Homo sapiens (Human) - NEDD8 gene & protein
... on the biological properties of the protein.,p>,a href='/help/mutagen' target='_top'>More...,/a>,/p>Mutagenesisi. 72. A → R: ... Biological process. Ubl conjugation pathway. Enzyme and pathway databases. Reactome - a knowledgebase of biological pathways ... help/gene_ontology' target='_top'>More...,/a>,/p>GO - Biological processi. *anatomical structure morphogenesis Source: ProtInc ... p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of ...
  https://www.uniprot.org/uniprot/Q15843