*  Loss of stromal androgen receptor leads to suppressed prostate tumourigenesis via modulation of pro-inflammatory cytokines...
B mediate high level expression of chemokine genes CCL3 and CCL4 by human chondrocytes in response to IL-1{beta}. J Biol Chem ... gene was originally identified as a tumour suppressor gene located at chromosome 10q23 (Myers et al, 1997). The PTEN gene is ... Ma WL, Hsu CL, Wu MH, Wu CT, Wu CC, Lai JJ, Jou YS, Chen CW, Yeh S, Chang C (2008) Androgen receptor is a new potential ... The biallelic mutation of the PTEN gene or the 2nd hit of loss-of-function in tumour suppressor genes could promote advanced ...
  http://onlinelibrary.wiley.com/doi/10.1002/emmm.201101140/full?globalMessage=0
*  CCR1 - Wikipedia
This gene encodes a member of the beta chemokine receptor family, which belongs to G protein-coupled receptors. The ligands of ... this receptor include CCL3 (or MIP-1 alpha), CCL5 (or RANTES), CCL7 (or MCP-3), and CCL23 (or MPIF-1). Chemokines and their ... This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CXCR1, are found to form a gene cluster on ... Daugherty BL, Springer MS (April 1997). "The beta-chemokine receptor genes CCR1 (CMKBR1), CCR2 (CMKBR2), and CCR3 (CMKBR3) ...
  https://en.wikipedia.org/wiki/CCR1
*  CCL4 - Wikipedia
1995). "Molecular characterization of two murine eosinophil beta chemokine receptors". J. Immunol. 155 (11): 5299-305. PMID ... Chemokine (C-C motif) ligand 4, also known as CCL4, is a protein which in humans is encoded by the CCL4 gene. CCL4, also known ... Perforin-low memory CD8+ T cells that normally synthesize MIP-1-beta. CCL4 has been shown to interact with CCL3. Macrophage ... Combadiere C, Ahuja SK, Murphy PM (1995). "Cloning and functional expression of a human eosinophil CC chemokine receptor". J. ...
  https://en.wikipedia.org/wiki/CCL4
*  CCR5 - Wikipedia
"CCR5 - chemokine (C-C motif) receptor 5 (gene/pseudogene)". Genetics Home Reference. Samson M, Labbe O, Mollereau C, Vassart G ... The CCR5 protein belongs to the beta chemokine receptors family of integral membrane proteins. It is a G protein-coupled ... receptor which functions as a chemokine receptor in the CC chemokine group. CCR5's cognate ligands include CCL3, CCL4 (also ... and HIV co-receptor activity. HIV-1 most commonly uses the chemokine receptors CCR5 and/or CXCR4 as co-receptors to enter ...
  https://en.wikipedia.org/wiki/CCR5
*  Index of immunology articles - Wikipedia
... alpha Interleukin 8 receptor, beta Interleukin receptor Interleukin-1 receptor Interleukin-1 receptor family Interleukin-1 ... C-C chemokine receptor type 6 C-C chemokine receptor type 7 Calreticulin Cancer immunology Cancer immunoprevention Cancer ... gene) CCR4 CCR5 CCR8 (gene) CCR9 CCRL1 CCRL2 CD117 CD32B CD4 CD4+ T cells and antitumor immunity CD74 CD94/NKG2 Cell-mediated ... CCL1 CCL11 CCL12 CCL13 CCL14 CCL15 CCL16 CCL17 CCL18 CCL19 CCL2 CCL20 CCL21 CCL22 CCL23 CCL24 CCL25 CCL26 CCL27 CCL28 CCL3 CCL5 ...
  https://en.wikipedia.org/wiki/Index_of_immunology_articles
*  CCL3L1 C-C motif chemokine ligand 3 like 1 [Homo sapiens (human)] - Gene - NCBI
Studies indicate beta-defensins (DEFB4, DEFB103, DEFB104), chemokine ligand 3 like 1 (CCL3L1), Fc gamma receptor 3B (FCGR3B), ... Found no association between four CCL3L CNV strata and HIV status , CD4 T-cell count, viral load , or CCL3 protein levels. ... The protein encoded by this gene binds to several chemokine receptors, including chemokine binding protein 2 and chemokine (C-C ... Gene Ontology Provided by GOA Function. Evidence Code. Pubs. CCR chemokine receptor binding IBA Inferred from Biological aspect ...
  https://www.ncbi.nlm.nih.gov/gene/6349
*  CCL4L1 - Wikipedia
"The assignment of chemokine-chemokine receptor pairs: TARC and MIP-1 beta are not ligands for human CC-chemokine receptor 8". ... Townson JR, Barcellos LF, Nibbs RJ (2002). "Gene copy number regulates the production of the human chemokine CCL3-L1". Eur. J. ... C-C motif chemokine 4-like is a protein that in humans is encoded by the CCL4L1 gene. This gene is one of several cytokine ... Guan E, Wang J, Roderiquez G, Norcross MA (2002). "Natural truncation of the chemokine MIP-1 beta /CCL4 affects receptor ...
  https://en.wikipedia.org/wiki/CCL4L1
*  CC chemokine receptors - Wikipedia
CC chemokine receptors (or beta chemokine receptors) are integral membrane proteins that specifically bind and respond to ... The CC chemokines CCL3, CCL5, CCL17 and CCL22 signal through this receptor. CCR5 is expressed on several cell types including ... CCR1 was the first CC chemokine receptor identified and binds multiple inflammatory/inducible (see inducible gene) CC ... The orphan chemokine receptor G protein-coupled receptor-2 (GPR-2, CCR10) binds the skin-associated chemokine CCL27 (CTACK/ALP/ ...
  https://en.wikipedia.org/wiki/CC_chemokine_receptors
*  Assessment of neuroinflammation in a mouse model of obesity and β-amyloidosis using PET | Journal of Neuroinflammation | Full...
In vivo TSPO signals were associated with inflammatory markers including CXCL1, CXCL2, CXCL12, CCL3, CCL5, TIMP-1, G-CSF, sICAM ... for 3 months and intracerebroventricularly infused with vehicle or human beta amyloid 1-42 (Aβ42). We assessed obesity-induced ... CCL2 and CCL3 chemokine gene expression and their receptors in human visceral and subcutaneous adipose tissue is associated ... Wang Q, Xu Y, Chen JC, Qin YY, Liu M, Liu Y, Xie MJ, Yu ZY, Zhu Z, Wang W. Stromal cell-derived factor 1alpha decreases beta- ...
  https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-016-0700-x
*  CCL3 - Wikipedia
... is a protein that in humans is encoded by the CCL3 gene. CCL3 is a cytokine belonging to the CC chemokine family that is ... 1988) demonstrated 2 protein components of MIP1, called by them alpha (CCL3, this protein) and beta (CCL4). CCL3 produces a ... the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes through binding to the receptors ... Human CCL3 genome location and CCL3 gene details page in the UCSC Genome Browser. Menten P, Wuyts A, Van Damme J (Dec 2002). " ...
  https://en.wikipedia.org/wiki/CCL3
*  GAPDH | definition of GAPDH by Medical dictionary
Housekeeping genes, such as [alpha]-TUB ([alpha]-Tubulin), [beta]-actin (Beta actin), 18s rRNA (18s ribosomal RNA), 28s rRNA ( ... Following reverse transcription, the cDNA was used as template for amplification of CC chemokine ligand 3 (CCL3) and GAPDH ... Abbreviations: FGFR, fibroblast growth factor receptor; FRS2[alpha], FGFR substrate protein-2[alpha]; GAPDH, glyceraldehyde 3- ... PCR amplification of chemokines and GAPDH in Macrophages. mRNA expression of chemokine genes in bovine tuberculosis infected ...
  http://medical-dictionary.thefreedictionary.com/GAPDH
*  Nanobodies
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions ... CCL3, also known as Macrophage inflammatory protein-1α (MIP-1α), is a cytokine belonging to the CC chemokine family that is ... 1988) demonstrated 2 protein components of MIP1, called by them alpha and beta. ... The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine ...
  http://invivosaglik.com/nanobodies_63_en.html
*  Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I (ADCYAP1R1) ELISA Kits
... increased macrophage resistance to HIV-1 replication by inducing the synthesis of beta-chemokines CCL3 (show CCL3 ELISA Kits) ... This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares ... PACAP receptor 1 , PACAP type I receptor , PACAP-R1 , pituitary adenylate cyclase activating polypeptide 1 receptor type I ... ADCYAP receptor type I (adcyap1r1) Elisa Kit * adenylate cyclase activating polypeptide 1 (pituitary) receptor type I S ...
  http://www.antibodies-online.com/neurotrophin-signaling-pathway-pathway-29/adcyap1r1-elisa-kit-205/
*  Interactive Effects of Morphine on HIV Infection: Role in HIV-Associated Neurocognitive Disorder
47]. Morphine regulates gene expression of alpha- and beta-chemokines and their receptors on astroglial cells via the opioid mu ... and CCL3 (MIP-1α) protein and mRNA expression levels were significantly exacerbated when exposed to Tat and morphine together ... and beta-chemokines and their receptors on astroGlial cells via the opioid mu receptor," The Journal of Immunology, vol. 169, ... "Chemokine and chemokine-receptor expression in human Glial elements: induction by the HIV protein, Tat, and chemokine ...
  https://www.hindawi.com/journals/art/2012/953678/
*  Macrophage inflammatory protein - Wikipedia
"High-resolution solution structure of the beta chemokine hMIP-1 beta by multidimensional NMR". Science. 263 (5154): 1762-1767. ... The genes for CCL3 and CCL4 are both located on human chromosome 17. They are produced by many cells, particularly macrophages ... Polymerization buries receptor-binding sites of MIP-1, thus depolymerization mutations enhance MIP-1 to arrest monocytes onto ... December 2010). "Polymerization of MIP-1 chemokine (CCL3 and CCL4) and clearance of MIP-1 by insulin-degrading enzyme". EMBO J ...
  https://en.wikipedia.org/wiki/Macrophage_inflammatory_protein
*  Anti-HMGB1 antibody [HAP46.5] (ab12029) | Abcam
Mediates the release of cytokines/chemokines such as TNF, IL-1, IL-6, IL-8, CCL2, CCL3, CCL4 and CXCL10 (PubMed:12765338, ... Can bind to IL1-beta and signals through the IL1R1:IL1RAP receptor complex (PubMed:18250463). Binding to class A CpG activates ... Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters ... In the extracellular compartment fully reduced HMGB1 (released by necrosis) acts as a chemokine, disulfide HMGB1 (actively ...
  http://www.abcam.com/hmgb1-antibody-hap465-ab12029.html
*  Yang Hu, MD, Ph.D | Stanford Medicine Profiles
... in response to chemokines CCL3 and CCL5 that recruit DCs to inflammatory sites, but not the lymphoid-homing chemokine CCL21. ... by TLR ligands induces expression of IFN-beta and autocrine activation of IFN-inducible Stat1-dependent genes important for DC ... Costimulation of chemokine receptor signaling by matrix metalloproteinase-9 mediates enhanced migration of IFN-alpha dendritic ... Thus, cell motility is regulated by integrating signaling inputs from chemokine receptors and molecules such as MMP-9, CD11b, ...
  https://med.stanford.edu/profiles/yang-hu
*  Frontiers | Peroxisome proliferator-activated receptor agonists modulate neuropathic pain: a link to chemokines? | Frontiers in...
... pain ameliorating effects and suppression of inflammatory gene expression, including chemokines. In early clinical research, ... Peroxisome proliferator-activated receptors are a family of nuclear receptors known for their roles in metabolism. Recent ... Peroxisome proliferator-activated receptors are a family of nuclear receptors known for their roles in metabolism. Recent ... pain ameliorating effects and suppression of inflammatory gene expression, including chemokines. In early clinical research, ...
  https://www.frontiersin.org/articles/10.3389/fncel.2014.00238/full
*  005427 - B6.129P2-Ccr5|tm1Kuz|/J
... receptor 5 in these knock-out mice affects immune and a number of other physiological responses. They are useful for widespread ... Gene Symbol and Name. Ccr5, chemokine (C-C motif) receptor 5. Gene Synonym(s). CC-CKR-5; CCCKR5; CCR-5; CD195; CKR-5; CKR5; ... Evidences of the cooperative role of the chemokines CCL3, CCL4 and CCL5 and its receptors CCR1+ and CCR5+ in RANKL+ cell ... CC chemokine receptor 5 signaling pathway in the neuroinflammatory response and cognitive deficits induced by beta-amyloid ...
  https://www.jax.org/strain/005427
*  CC chemokine receptor 4 modulates Toll-like receptor 9-mediated innate immunity and signaling
... of the CC chemokines TARC and macrophage inflammatory protein-1 beta as novel functional ligands for the CCR8 receptor. Eur J ... A) Gene expressions of FIZZ1, Arginase-1, and Mannose receptor (proteins expressed by alternatively activated (M2-skewed) cells ... CCL3, and IL-12 p70 were measured. Inhibitors of Akt, JNK, and IKK, but not p38 MAPK suppressed the expression of TNF-α, CCL3, ... CC chemokine receptor 4 (CCR4), a specific receptor for CCL17 and CCL22, is generally recognized as a receptor expressed on T ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2925393/
*  The Chemokine-binding Proteins Encoded by Bovine Papular Stomatitis Virus and Parapoxvirus of Red Deer in New Zealand:...
... and CCL3 chemokines, the BPSV-CBP was shown to cause a significant reduction in cell migration at a molar ratio of chemokine-to ... whereas CC chemokines are chemoattractants for monocytes. The CBP genes have been identified in Orthopoxviruses and ... cell line and shown as Ly-6Ghi CD11bhi cells that express the chemokine receptor CXCR2. After optimizing the neutrophil ... Moreover, structural modelling based on the crystal structure of the orf virus CBP, predicted a similar beta-sheet sandwich for ...
  https://ourarchive.otago.ac.nz/handle/10523/7545
*  The 'immunologic advantage' of HIV-exposed seronegative indi... : AIDS
... that confers cellular resistance to HIV infection is the homozygous 32 base-pair deletion in the CCR5 chemokine receptor gene ( ... African infants' CCL3 gene copies influence perinatal HIV transmission in the absence of maternal nevirapine. AIDS 2007; 21: ... and beta-chemokines, is increased [10-12], secretory HIV-specific IgA as well as T helper cells and CTLs can be observed in ... Vitamin D receptor gene sequence variations and polymorphisms in the transcriptional regulator gene interferon regulatory ...
  https://journals.lww.com/aidsonline/fulltext/2009/01140/the__immunologic_advantage__of_hiv_exposed.2.aspx
*  Effector stage CC chemokine receptor-1 selective antagonism reduces multiple sclerosis-like rat disease. - Semantic Scholar
In situ hybridization histochemistry revealed local production of the CCR1 ligands CCL3 (MIP-1 alpha) and CCL5 (RANTES), as ... We have studied the role of the chemokine receptor CCR1 during the effector stage of myelin oligodendrocyte glycoprotein- ... Involvement of beta-chemokines in the development of inflammatory demyelination. *Ileana Banisor, Thomas P Leist, Bernadette ... Encephalomyelitis Genes for Experimental Autoimmune as Candidate CLDN 4 and Ncf-1 Reveals Eae 5 Advanced Intercross Line ...
  https://www.semanticscholar.org/paper/Effector-stage-CC-chemokine-receptor-1-selective-Eltayeb-Sunnemark/6e38db183d936c9700591888e8092e14ed6ad8d0
*  PPBP and DEFA1/DEFA3 genes in hyperlipidaemia as feasible synergistic inflammatory biomarkers for coronary heart disease |...
α-defensin (DEFA1/DEFA3), pro-platelet basic protein (PPBP), and beta and alpha2 hemoglobin mRNA expression was significantly ... Gene profiling was investigated in peripheral blood mononuclear cells using DNA microarrays. Eight selected genes expressed ... To determine whether genes showing altered expression in hyperlipidaemia (H) and coronary heart disease (CHD) patients compared ... chemokine ligand 3(CCL3), and 4 (CCL4), and interleukin-1β (IL-1β). Table 1 lists the primers designed to amplify these genes ...
  https://lipidworld.biomedcentral.com/articles/10.1186/s12944-017-0471-0