*  Plus it
These 23 patients were tested for the presence of ALK gene rearrangement using the break-apart FISH assay and/or 2 PCR ... Of all patients in this cohort, the 23 shown had sufficient tissue for assessing ALK gene rearrangement status. D, Kaplan-Meier ... Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement ... Additional retrospective biomarker testing included gene mutational analysis, EGFR amplification, and ALK rearrangement, all ...
  http://clincancerres.aacrjournals.org/content/19/11/3068
*  58022 y[1] w[*]; Mi{y[+mDint2]=MIC}MI13103
It is possible that there is an internal rearrangement of the MiMIC transposon involving the 3prime end. May be segregating ... Donor: Gene Disruption Project; Donor's Source: Hugo J. Bellen, Baylor College of Medicine. ...
  http://flystocks.bio.indiana.edu/Reports/58022.html
*  Chemical Confounds | GARDEN OF PUZZLING DELIGHTS | GameBoomers Community
Note that the components are listed alphabetically so some letter rearrangement may be necessary to determine the answer. You ... 7. ge,ne,si,s. _________________________. Why didn't Noah swat those two mosquitoes? Top ...
  http://www.gameboomers.com/forum/ubbthreads.php/topics/864232/Chemical_Confounds.html
*  A Comparative Study of ERG Status Assessment on DNA, mRNA, and Protein Levels Using Unique Samples from a Swedish Biopsy Cohort
ERG rearrangement was found in 56% of the cases. Comparing ERG rearrangement status by FISH with ERG overexpression and TMPRSS2 ... prostate cancer, ERG, gene fusion National Category Clinical Laboratory Medicine Identifiers. URN: urn:nbn:se:oru:diva-56739DOI ... The ERG rearrangement is identified in approximately 50% of prostate cancer screened cohorts and is known to be highly specific ... We show that the ERG antibody highly correlates with the ERG rearrangement with high sensitivity and specificity. We also ...
  http://oru.diva-portal.org/smash/record.jsf?pid=diva2:1083959
*  Antigen receptor gene rearrangements reflect on the heterogeneity of adult Acute Lymphoblastic Leukaemia (ALL) with...
Molecular monitoring of clonal Immunoglobulin and T cell receptor (IG/TR) gene rearrangements has become an important tool in ... of 473 IG/TR rearrangements identified in 229 adults with ALL was carried out. Distinct variable-gene usage profiles were ... The heterogeneity in clinical outcome is suggested by the basic molecular processes of antigen receptor gene rearrangements as ... In order to determine whether certain features of the patient-specific rearrangements could hold further prognostic clues or ...
  https://www.ndph.ox.ac.uk/publications/95979
*  Genes | Free Full-Text | A Narrowing of the Phenotypic Diversity Range after Large Rearrangements of the Karyotype in...
Large karyotype rearrangements are associated with a decrease in ecological and morphological diversity in salmonids. In the ... above example, genome rearrangements seem to distort the function of the genetic systems that are responsible for the ... The problem of how a gradual development of ecological and morphological adaptations combines with large genome rearrangements ... Genes 2017, 8, 297. AMA Style. Makhrov AA. A Narrowing of the Phenotypic Diversity Range after Large Rearrangements of the ...
  http://www.mdpi.com/2073-4425/8/11/297
*  HKU Scholars Hub: A study of clonality of lymphoma of SJL mice using immunoglobulin gene rearrangements and murine leukaemia...
Conference Paper: A study of clonality of lymphoma of SJL mice using immunoglobulin gene rearrangements and murine leukaemia ... A study of clonality of lymphoma of SJL mice using immunoglobulin gene rearrangements and murine leukaemia virus integration. ... A study of clonality of lymphoma of SJL mice using immunoglobulin gene rearrangements and murine leukaemia virus integration. ...
  http://hub.hku.hk/handle/10722/104519
*  Developmentally Programmed DNA Rearrangements
... rearrangements are structural reorganisations of the genome that occur reproducibly during the development of a variety of ... like excision during the developmental rearrangement of key genes in Tetrahymena thermophila. Genes & Development 30 (24): 2724 ... Nonreciprocal gene conversion of an internal VSG gene (D) into an active telomeric expression site. The expressed VSG gene is ... In the majority of cases, programmed DNA rearrangements function to alter gene expression. V(D)J recombination is a DNA ...
  http://www.els.net/WileyCDA/ElsArticle/refId-a0000595.html
*  Hematogones | Flow Cytometry
... gene rearrangement studies.. The earliest recognizable B-lineage precursors expresses CD34 in combination with CD38, CD19, high ...
  http://clinicalflow.com/hematogones
*  Chromothripsis - Wikipedia
42 chromosomal rearrangements were found in the long arm of chromosome 4 and a significant number of rearrangements were found ... Mutations in FANCM gene cause increased micronucleus formation and hence extreme chromothripsis. As well as cells encompassing ... Mutations in the TP53 gene are important for the maintenance of genome stability has been seen to be a predisposing mutation ... Poor clinical outcome in neuroblastomas (such as those caused by deletion of the FANC gene in Fanconi Anaemia) has been linked ...
  https://en.wikipedia.org/wiki/Chromothripsis
*  B-cell Immunoglobulin Gene Rearrangement
... and what the results of B-cell immunoglobulin gene rearrangement tests might mean ... Describes how B-cell immunoglobulin gene rearrangement tests are used, when they are ordered, ... The final order in which the genes are rearranged is called a gene rearrangement profile. Within any normal population (sample ... B-cell immunoglobulin gene rearrangement tests are used to help diagnose non-Hodgkin B-cell lymphomas and evaluate for residual ...
  https://labtestsonline.org/tests/b-cell-immunoglobulin-gene-rearrangement
*  em ALK em Mutation (Gene Rearrangement) | LabCorp
ALK Gene Rearrangement; ALK Gene Fusion Formal name:. ALK (Anaplastic Lymphoma Receptor Tyrosine Kinase) Gene Rearrangement ... ALK gene rearrangements are most often seen in light smokers or non-smokers with adenocarcinoma non-small cell lung cancers, ... This testing detects the presence of the most common ALK gene rearrangements in the DNA of cells in tumor tissue or the ... A person whose cancer does not have an ALK gene rearrangement is not likely to benefit from ALK kinase inhibitor drug therapy. ...
  https://www.labcorp.com/help/patient-test-info/emalkem-mutation-gene-rearrangement
*  480716: B-Cell, IgH Gene Rearrangements | LabCorp
B-Cell Gene Rearrangement, PCR. 480827. B Clonal Size. N/A. 480716. B-Cell Gene Rearrangement, PCR. 480778. Block Number:. N/A ... B-Cell Gene Rearrangement, PCR. 480720. Methodology:. 49549-9. 480716. B-Cell Gene Rearrangement, PCR. 480821. References:. N/A ... B-Cell Gene Rearrangement, PCR. 480717. B-Cell PCR Interpretation. 21747-1. ... This assay can be used to detect clonal immunoglobulin receptor heavy chain gene rearrangements in blood, bone marrow, and ...
  https://www.labcorp.com/test-menu/20871/
*  Programmed gene rearrangements altering gene expression | Science
Programmed gene rearrangements are used in nature to to alter gene copy number (gene amplification and deletion), to create ... Gene rearrangements altering gene expression have mainly been found in some unicellular organisms. They allow a fraction of the ... In DNA transposition a gene moves into an expression site where it displaces its predecessor by gene conversion. ... as in the formation of mammalian immunoglobulin genes), or to control the expression of a set of genes that code for the same ...
  http://science.sciencemag.org/content/235/4789/658
*  Molecular Diagnostics Lab - T-cell Receptor Beta (TCRB) Gene Rearrangement (PCR) | MD Anderson Cancer Center
T-cell Receptor Beta (TCRB) Gene Rearrangement (PCR). Indication. - Assessment of clonality in suspected T-cell ... Clonal TCRB rearrangements can be seen in B-cell acute lymphoblastic leukemias and are thus not definitive for lineage in ... PCR products and non-denaturing capillary electrophoresis is performed to detect only complete TCRB rearrangements. ...
  https://www.mdanderson.org/research/research-resources/core-facilities/molecular-diagnostics-lab/services/t-cell-receptor-beta-gene-rearrangement.html
*  B cell gene rearrangement Dictionary Definition and More from Dictionary.net
Definitions of B Cell Gene Rearrangement. * Ordered rearrangement of B- lymphocyte variable gene regions coding for the ... previousB cell epitopes next B cell gene rearrangements B cell gene rearrangement. ...
  http://www.dictionary.net/b%20cell%20gene%20rearrangement
*  Gene placement and competition control T cell receptor γ variable region gene rearrangement | JEM
Gene-targeted mice to test the role of gene location in programmed V gene rearrangement. To address the role of V gene location ... D gene segments. The γ locus consists of three functional Jγ-Cγ genes and up to seven Vγ genes, with four of the Vγ genes ... and that rearrangement of the downstream Vγ genes competitively inhibits rearrangement of the upstream Vγ2 gene segment. ... which switches to a preference for rearrangements of the upstream Vγ2 and Vγ5 gene rearrangements in the adult. Our gene ...
  http://jem.rupress.org/content/205/4/929
*  Spontaneous Splenic Rupture in Acute Myeloid Leukemia with Mixed-Lineage Leukemia Gene Rearrangement | OMICS International
Spontaneous Splenic Rupture in Acute Myeloid Leukemia with Mixed-Lineage Leukemia Gene Rearrangement Gardner JA1*, Bao L2 and ... Acute leukemia with rearrangements in the MLL gene on chromosome 11q23 is generally associated with an unfavorable prognosis ... analysis identified an atypical MLL/KMT2A/11q23 rearrangement with an extra copy of the 5' MLL/11q23 gene along with two intact ... TSpontaneous Splenic Rupture in Acute Myeloid Leukemia with Mixed-Lineage Leukemia Gene Rearrangement. Med Rep Case Stud 1: 119 ...
  https://www.omicsonline.org/open-access/spontaneous-splenic-rupture-in-acute-myeloid-leukemia-with-mixedlineage-leukemia-gene-rearrangement-mrcs-1000119.php?aid=78429
*  bcl-2 gene rearrangement test
... What is this test?. This test identifies the rearrangement of a gene called bcl-2 in the body. ... 7] Crisan D: BCL-2 gene rearrangements in lymphoid malignancies. Clin Lab Med 1996; 16(1):23-47. ... 4] Sanchez-Vega B, Vega F, Medeiros LJ, et al: Quantification of bcl-2/JH fusion sequences and a control gene by multiplex real ... 2] Landetto M, Drandi D, Compagno M, et al: PCR-detectable nonneoplastic Bcl-2/IgH rearrangements are common in normal subjects ...
  https://www.allinahealth.org/CCS/doc/Thomson%20Consumer%20Lab%20Database/49/150348.htm
*  Mutation Status and Immunoglobulin Gene Rearrangements in Patients from Northwest and Central Region of Spain with Chronic...
PCR Amplification of IgH Rearrangements. IGHV gene rearrangements were amplified by reverse transcription-PCR according to ERIC ... Interestingly, within IGHV5 family, IGHV5-51 genes appeared to be mostly unmutated (. ). Figure 1 shows IGHV gene segment usage ... IGHV4-34 had previously been reported to be among the most frequently used genes in CLL rearrangements [12]. In our cohort, ... T. Karan-Djurasevic, V. Palibrk, T. Kostic et al., "Mutational status and gene repertoire of IGHV-IGHD-IGHJ rearrangements in ...
  https://www.hindawi.com/journals/bmri/2014/257517/
*  Staging B-Cell Development and the Role of Ig Gene Rearrangement in B Lineage Progression | Springer for Research & Development
1998) Staging B-Cell Development and the Role of Ig Gene Rearrangement in B Lineage Progression. In: Monroe J.G., Rothenberg E. ... Staging B-Cell Development and the Role of Ig Gene Rearrangement in B Lineage Progression. ... rearrangement of heavy but not light chain genes. Cell 27, 381-390.PubMedCrossRefGoogle Scholar ... Frequent aberrant immunoglobulin gene rearrangements in pro-B cells revealed by a Bcl-xL transgene. Immunity 4, 291-299.PubMed ...
  https://rd.springer.com/chapter/10.1007/978-1-4757-2778-4_14
*  FOXO1 (FKHR) (13q14) Gene Rearrangement by FISH
2001497 - FOXO1 (FKHR) (13q14) Gene Rearrangement by FISH. http://ltd.aruplab.com/tests/pub/2001497 ...
  http://ltd.aruplab.com/Tests/Pub/2001497
*  Molecular Analysis of Gene Rearrangements and Mutations in Acute Leukemias and Myeloid Neoplasms - Current Protocols
Molecular Analysis of Gene Rearrangements and Mutations in Acute Leukemias and Myeloid Neoplasms. ... Determining the repertoire of IGH gene rearrangements to develop molecular markers for minimal residual disease in B‐lineage ... Analysis of minimal residual disease by Ig/TCR gene rearrangements: Guidelines for interpretation of real‐time quantitative PCR ... These alterations include chromosomal rearrangements leading to oncogenic fusion proteins or alteration of gene expression by ...
  http://www.currentprotocols.com/WileyCDA/CPUnit/refId-hg1004.html?quicktabs_cp=toc
*  Specific T cell receptor gene rearrangements at the site of muscle degeneration in Duchenne muscular dystrophy. | The Journal...
Specific T cell receptor gene rearrangements at the site of muscle degeneration in Duchenne muscular dystrophy.. E Gussoni, G K ... Specific T cell receptor gene rearrangements at the site of muscle degeneration in Duchenne muscular dystrophy. ... Specific T cell receptor gene rearrangements at the site of muscle degeneration in Duchenne muscular dystrophy. ... Specific T cell receptor gene rearrangements at the site of muscle degeneration in Duchenne muscular dystrophy. ...
  http://www.jimmunol.org/content/153/10/4798.long
*  Frequency of known gene rearrangements in endometrial stromal tumors. - Semantic Scholar
... whereas no rearrangements were observed in UESs or in any other non-EST studied. Our data confirm that gene rearrangements are ... The presence of identical gene rearrangements in both uterine and extrauterine ESTs suggests a similar pathogenesis. The ... Rearrangements were detected in 42 of 78 (54%) uterine ESTs, with JAZF1-SUZ12 fusion found in 50% of ESNs and in 33% of ESSs ... presence of detectable gene rearrangements in uterine ESS may predict better patient outcome. ...
  https://www.semanticscholar.org/paper/Frequency-of-known-gene-rearrangements-in-stromal-Chiang-Ali/bba9a3fa93f7159fd739664638ed592f88d7eb88