*  UBE2K Gene - GeneCards | UBE2K Protein | UBE2K Antibody
... proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium ... Protein Coding), Ubiquitin Conjugating Enzyme E2 K, including: function, ... 200 amino acids. Molecular mass:. 22407 Da. Quaternary structure:. *Interacts with RNF138/NARF. Interacts with BRCA1. ... Summaries for UBE2K Gene Entrez Gene Summary for UBE2K Gene. * The protein encoded by this gene belongs to the ubiquitin- ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=UBE2K
*  BRAT1 Gene - GeneCards | BRAT1 Protein | BRAT1 Antibody
Protein Coding), BRCA1 Associated ATM Activator 1, including: function, proteins, disorders, pathways, orthologs, and ... Protein attributes for BRAT1 Gene. Size:. 821 amino acids. Molecular mass:. 88119 Da. Quaternary structure:. *Interacts with ... The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein ... Domains & Families for BRAT1 Gene Gene Families for BRAT1 Gene. Human Protein Atlas (HPA):. *Disease related genes ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=BRAT1&rf=/home/genecards/current/website/carddisp.pl&asd=13
*  DCLRE1C Gene - GeneCards | DCR1C Protein | DCR1C Antibody
... proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium ... Protein Coding), DNA Cross-Link Repair 1C, including: function, ... Protein attributes for DCLRE1C Gene. Size:. 692 amino acids. ... Interacts with ATM, BRCA1, PRKDC and TP53BP1. Also exhibits ATM- and phosphorylation-dependent interaction with the MRN complex ... Summaries for DCLRE1C Gene Entrez Gene Summary for DCLRE1C Gene. * This gene encodes a nuclear protein that is involved in V(D) ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=DCLRE1C
*  DNA Repair Gene XRCC1 Polymorphisms, Smoking, and Bladder Cancer Risk | Cancer Epidemiology, Biomarkers & Prevention
... to the COOH-terminal region of the breast cancer susceptibility gene BRCA1 and are thought to mediate specific protein-protein ... Nonconservative amino acid substitution variants exist at polymorphic frequency in DNA repair genes in healthy humans.. Cancer ... Nash R. A., Caldecott K. W., Barnes D. E., Lindahl T. XRCC1 protein interacts with one of two distinct forms of DNA ligase III ... The XRCC1 gene protein plays an important role in BER by serving as a scaffold for other repair enzymes and by recognizing ...
  http://cebp.aacrjournals.org/content/10/2/125.full
*  BLM Gene - GeneCards | BLM Protein | BLM Antibody
... proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium ... Protein Coding), Bloom Syndrome RecQ Like Helicase, including: function, ... Protein attributes for BLM Gene. Size:. 1417 amino acids. Molecular mass:. 159000 Da. Quaternary structure:. *Part of the BRCA1 ... Selected Interacting proteins: P54132-BLM_HUMAN ENSP00000347232 for BLM Gene via MINT STRING UniProtKB IID ...
  http://www.genecards.org/cgi-bin/carddisp.pl?id_type=hgnc&id=1058
*  PMS2 Gene - GeneCards | PMS2 Protein | PMS2 Antibody
... proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium ... Protein Coding), PMS1 Homolog 2, Mismatch Repair System Component, including: function, ... Protein attributes for PMS2 Gene. Size:. 862 amino acids. Molecular mass:. 95797 Da. Quaternary structure:. *Heterodimer of ... Selected Interacting proteins: P54278-PMS2_HUMAN ENSP00000265849 for PMS2 Gene via IID STRING UniProtKB MINT ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=PMS2
*  PTP4A2 Gene - GeneCards | TP4A2 Protein | TP4A2 Antibody
Protein Coding), Protein Tyrosine Phosphatase Type IVA, Member 2, including: function, proteins, disorders, pathways, orthologs ... 167 amino acids. Molecular mass:. 19127 Da. Quaternary structure:. *In contrast to PTP4A1 and PTP4A3, does not interact with ... Interacts with RABGGTB.. Miscellaneous:. *A processed pseudogene with 96% sequence identity was found in the BRCA1 (113705) ... Interacting Proteins for PTP4A2 Gene. Selected Interacting proteins: Q12974-TP4A2_HUMAN for PTP4A2 Gene via MINT IID ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=PTP4A2&keywords=GH01G031802&prefilter=genomic_location
*  BABAM2 Gene - GeneCards | BABA2 Protein | BABA2 Antibody
Protein Coding), BRISC And BRCA1 A Complex Member 2, including: function, proteins, disorders, pathways, orthologs, and ... Protein attributes for BABAM2 Gene. Size:. 383 amino acids. Molecular mass:. 43552 Da. Quaternary structure:. *Component of the ... Entrez Gene Summary for BABAM2 Gene. * This gene encodes an anti-apoptotic, death receptor-associated protein that interacts ... Protein details for BABAM2 Gene (UniProtKB/Swiss-Prot). Protein Symbol:. Q9NXR7-BABA2_HUMAN. Recommended name:. BRISC and BRCA1 ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=BABAM2
*  Negative elongation factor - Wikipedia
Microsequencing analysis demonstrated that NELF-B was the protein previously identified as the protein encoded by the gene ... and was shown to interact with BRCA1. It is unknown whether or not NELF-C and NELF-D are peptides resulting from the same mRNA ... possibly differing only in an extra 9 amino acids for NELF-C at the N-terminus, or peptides from different mRNAs entirely. A ... In molecular biology, NELF (negative elongation factor) is a four-subunit protein (NELF-A, NELF-B, NELF-C/NELF-D, and NELF-E) ...
  https://en.wikipedia.org/wiki/Negative_elongation_factor
*  X chromosome studies and breast and ovarian carcinoma - UBC Library Open Collections
1994). The BRCA1 gene is large, at 24 exons and encoding 1863 amino acids in humans (Miki et al. 1994). The BRCA1 protein has ... at 3418 amino acids in length (Wooster et al. 1995). It is involved in homologous recombination, and interacts with BRCA1, ... The AR gene maps to Xq11-q12 and its protein is approximately 919 amino acids in length. AR protein size is variable due to the ... The ESR2 gene was discovered ten years after ESR1, maps to 14q23.2 and encodes a protein that is 530 amino acids in length ( ...
  https://open.library.ubc.ca/cIRcle/collections/ubctheses/24/items/1.0066174
*  Compensatory Functions and Interdependency of the DNA-Binding Domain of BRCA2 with the BRCA1-PALB2-BRCA2 Complex | Cancer...
The breast-cancer-susceptibility gene 2 (BRCA2) encodes a tumor-suppressor protein carrying 3,418 amino acids. Although the ... which consists of 3,418 amino acids. The BRCA2 protein interacts with PALB2 through the N-terminal segment, with RAD51 through ... PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene. Nat Genet 2007;39:165-7. ... Because PALB2 mediates between BRCA1 and BRCA2 to form a complex, the BRCA2BRC3tr protein might also require BRCA1 to promote ...
  http://cancerres.aacrjournals.org/content/74/3/797
*  MDC1 polyclonal antibody - (PAB8487) - Products - Abnova
Gene Summary:. *The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and ... a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate ... This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs ... Mediator of DNA damage checkpoint protein 1 regulates BRCA1 localization and phosphorylation in DNA damage checkpoint control. ...
  http://www.abnova.com/products/products_detail.asp?catalog_id=PAB8487
*  The Association between GWAS-identified BARD1 Gene SNPs and Neuroblastoma Susceptibility in a Southern Chinese Population
This gene encodes a protein that can interact with the N-terminal region of BRCA1 both in vivo and in vitro [22]. The BARD1 ... SNPs may change the encoding amino acids (non-synonymous SNPs), may be silent (synonymous SNPs), or may occur in the non-coding ... Identification of a RING protein that can interact in vivo with the BRCA1 gene product. Nat Genet. 1996;14:430-40 ... Mutations in the BRCA1-associated RING domain (BARD1) gene in primary breast, ovarian and uterine cancers. Hum Mol Genet. 1998; ...
  http://www.medsci.org/v13p0133.htm
*  BAP1 antibody | acris-antibodies.com
... or BAP1 interacts with the RING finger domain of BRCA1. The N-terminal 240 amino acids of the predicted 729-amino acid… ... BRCA1-associated protein-1,' or BAP1 interacts with the RING finger domain of BRCA1. The N-terminal 240 amino acids of the ... It has been postulated that BAP1 is a tumor suppressor gene that functions in the BRCA1 growth control pathway.1 ... Recombinant protein of human BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) (BAP1). ...
  https://www.acris-antibodies.com/target/bap1-antibody.htm
*  IFI16 - Wikipedia
The protein localizes to the nucleoplasm and nucleoli, and interacts with p53, retinoblastoma-1 and BRCA1. It modulates p53 ... This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) ... The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. ... "Entrez Gene: IFI16 interferon, gamma-inducible protein 16". Liao, Jack C. C.; Lam, Robert; Brazda, Vaclav; Duan, Shili; ...
  https://en.wikipedia.org/wiki/IFI16
*  AXIN1 - Wikipedia
The full-length human protein comprises 862 amino acids with a (predicted) molecular mass of 96 kDa. The N-terminal RGS domain ... interacts with beta-catenin, GSK-3beta and APC and reduces the beta-catenin level". Genes Cells. 3 (6): 395-403. doi:10.1046/j. ... Many other large IDPs are affected by missense mutations, such as BRCA1, Adenomatous polyposis coli(APC), CREB-binding protein ... Axin-1 is a protein that in humans is encoded by the AXIN1 gene. This gene encodes a cytoplasmic protein which contains a ...
  https://en.wikipedia.org/wiki/AXIN1
*  BRCA1 - Wikipedia
... of BRCA1 protein. There are six known isoforms of BRCA1, with isoforms 1 and 2 comprising 1863 amino acids each.[citation ... BRCA1 interacts with the NELF-B (COBRA1) subunit of the NELF complex. Certain variations of the BRCA1 gene lead to an increased ... BRCA1 interacts with VCP. BRCA1 also interacts with c-Myc, and other proteins that are critical to maintain genome stability. ... BRCA1 and BRCA1 (/ˌbrækəˈwʌn/) are a human gene and its protein product, respectively. The official symbol (BRCA1, italic for ...
  https://en.wikipedia.org/wiki/BRCA1
*  CREB-binding protein - Wikipedia
... located between amino acids 977 and 1076. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal ... CREB-binding protein has been shown to interact with: TF2, AR, AIRE, BRCA1, C-jun, CSK, Ccaat-enhancer-binding proteins, CDX2, ... are dependent on acidic amino acid residues and protein-protein interaction". Nucleic Acids Research. 28 (5): 1106-13. doi: ... CREB-binding protein, also known as CREBBP or CBP, is a protein that in humans is encoded by the CREBBP gene. The CREB protein ...
  https://en.wikipedia.org/wiki/CREB-binding_protein
*  BRCA2 - Wikipedia
... and the cDNA has 10,254 base pairs coding for a protein of 3418 amino acids. The gene was first cloned by scientists at Myriad ... BRCA2 has been shown to interact with BRE, BARD1, BCCIP, BRCA1, BRCC3, BUB1B, CREBBP, C11orf30, FANCD2, FANCG, FLNA, HMG20B, ... BRCA1 and BRCA2 have been described as "breast cancer susceptibility genes" and "breast cancer susceptibility proteins". The ... BRCA2 contains a number of 39 amino acid repeats that are critical for binding to RAD51 (a key protein in DNA recombinational ...
  https://en.wikipedia.org/wiki/BRCA2
*  DNA repair and recombination protein RAD54-like - Wikipedia
It encodes a protein, composed of 747 amino acids, that is 52% identical to its yeast counterpart. These two proteins also ... Normally, RAD51 interacts with both BRCA1 and BRCA2 protein products to cause tumor suppression. This leads to the assumption ... DNA repair and recombination protein RAD54-like is a protein that in humans is encoded by the RAD54L gene. The protein encoded ... This N-terminal end interacts with both the free and bound ends of the RAD51 protein. RAD54 moves along the length of the DNA, ...
  https://en.wikipedia.org/wiki/DNA_repair_and_recombination_protein_RAD54-like
*  MSH3 - Wikipedia
... gene. MSH3 is encoded by 222,341 base pairs and creates a protein consisting of 1137 amino acids. MSH3 is typically expressed ... MSH3 has been shown to interact with MSH2, PCNA, and BRCA1. These interactions form protein complexes that are typically ... The N-terminal region of MSH3 (amino acids 126-250) contact the N-terminal region of MSH2 aa 378-625. The C-terminal regions ... DNA mismatch repair protein, MutS Homolog 3 (MSH3) is a human homologue of the bacterial mismatch repair protein MutS that ...
  https://en.wikipedia.org/wiki/MSH3
*  ATM serine/threonine kinase - Wikipedia
The ATM gene codes for a 350 kDa protein consisting of 3056 amino acids. ATM belongs to the superfamily of phosphatidylinositol ... Ataxia telangiectasia mutated has been shown to interact with: Abl gene, BRCA1, Bloom syndrome protein, DNA-PKcs, FANCD2, ... It mediates protein-protein interaction for example with the histone acetyltransferase TIP60 (HIV-1 Tat interacting protein 60 ... a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures". Genes Dev. 14 ...
  https://en.wikipedia.org/wiki/ATM_serine/threonine_kinase
*  RBBP7 Full-Length MS Protein Standard - Creative Proteomics
This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and ... This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It ... The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in ... Two transcript variants encoding different isoforms have been found for this gene. ...
  https://www.creative-proteomics.com/product/detail-cpfl317969_5941.htm
*  Beverly S. Mitchell, M.D. | Stanford Medicine Profiles
... end of the gene. The encoding protein consists of 345 amino acids with a calculated molecular size of 38.7 kDa and does not ... contains a BRCA1 C-terminal domain that has been shown to mediate interactions of proteins involved in DNA repair. The ... Tenascin C interacts with ecto-5'-nucleotidase (eN) and regulates adenosine generation in cancer cells Biochem Biophys Acta ... gene mutation in all clones sequenced resulting in the substitution of arginine for glutamine at amino acid 156 of the protein ...
  https://med.stanford.edu/profiles/beverly-mitchell
*  Plus it
BRCA2 contains eight BRC repeats located in the middle of the protein, each repeat consisting of 30 to 40 amino acids. Six of ... lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos. Genes Dev 1997; 11: 1226-41. ... the eight repeats have been shown to interact with RAD51 ( 15, 16). An evolutionarily conserved 29-amino-acid region (amino ... To examine the elution profile of pure AGT, we fractionated human recombinant AGT protein, which has 77% amino acids sequence ...
  http://cancerres.aacrjournals.org/content/68/23/9973