CXCR4 : Wikis (The Full Wiki)
... ligand-receptor pair (other chemokines tend to use several different chemokine receptors in a fairly "promiscuous" manner). ... CCR1 * CXCR3 * CCR3 (gene) * Interleukin 8 receptor, alpha * CCR4 * CXCR5 * CCR9 * Interleukin 8 receptor, beta ... "Molecular cloning of cDNAs encoding a LD78 receptor and putative leukocyte chemotactic peptide receptors.". Int. Immunol. 5 (10 ... C-C chemokine receptor activity. • C-X-C chemokine receptor activity. • myosin light chain binding. ...http://www.thefullwiki.org/CXCR4
CCR1 - Wikipedia
This gene encodes a member of the beta chemokine receptor family, which belongs to G protein-coupled receptors. The ligands of ... C-C chemokine receptor type 1 is a protein that in humans is encoded by the CCR1 gene. CCR1 has also recently been designated ... Human CCR1 genome location and CCR1 gene details page in the UCSC Genome Browser. "Chemokine Receptors: CCR1". IUPHAR Database ... Daugherty BL, Springer MS (April 1997). "The beta-chemokine receptor genes CCR1 (CMKBR1), CCR2 (CMKBR2), and CCR3 (CMKBR3) ...https://en.wikipedia.org/wiki/CCR1
anti-CCR1 antibody | GeneTex
... chemokine (C-C motif) receptor 1) for ELISA, ICC/IF, WB. Anti-CCR1 pAb (GTX13240) is tested in Human samples. 100% Ab-Assurance ... chemokine (C-C motif) receptor 1. Background. This gene encodes a member of the beta chemokine receptor family, which is ... Peptide sequence is < 50 % identical to other chemokine receptors in this region. ... This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on ...http://www.genetex.com/CCR1-antibody-GTX13240.html
Chemokine - Peptide - GPCR - Receptors - Products
Chemokine. The CCR1 receptor is a member of the beta chemokine receptor family (GPCR-A1). Chemokines and their receptors are ... The protein encoded by this gene is a receptor for fractalkine (CX3CR1). CX3CR1 and its ligand help control the migration and ... Following interaction with their specific chemokine ligands, chemokine receptors trigger a flux in intracellular calcium (Ca2+ ... 1] Chemokine receptors and their role in inflammation and infectious diseases. Murdoch C., Finn A. Blood 2000, 95, 3032-3043. [ ...https://www.axonmedchem.com/products/receptors/gpcr/peptide/chemokine
MPIF-1 elisa kit | Monkey Myeloid Progenitor Inhibitory Factor 1 ELISA Kit-AAB51134.1
Molecular Function: heparin binding; CCR1 chemokine receptor binding; chemokine activity. Biological Process: cellular calcium ... This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted ... Chemokine Signaling Pathway antibodies. Chemokine Signaling Pathway Diagram. Class A/1 (Rhodopsin-like Receptors) Pathway ... C-C motif chemokine 23; C6 beta-chemokine; macrophage inflammatory protein 3; myeloid progenitor inhibitory factor 1; small ...https://www.mybiosource.com/prods/ELISA-Kit/Monkey/Myeloid-Progenitor-Inhibitory-Factor-1/MPIF-1/datasheet.php?products_id=734515
CCR3 (gene) - Wikipedia
Daugherty BL, Springer MS (1997). "The beta-chemokine receptor genes CCR1 (CMKBR1), CCR2 (CMKBR2), and CCR3 (CMKBR3) cluster ... Samson M, Soularue P, Vassart G, Parmentier M (1997). "The genes encoding the human CC-chemokine receptors CC-CKR1 to CC-CKR5 ( ... This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. ... C-C chemokine receptor type 3 is a protein that in humans is encoded by the CCR3 gene. CCR3 has also recently been designated ...https://en.wikipedia.org/wiki/CCR3_(gene)
CCRL2 - Wikipedia
Daugherty BL, Springer MS (1997). "The beta-chemokine receptor genes CCR1 (CMKBR1), CCR2 (CMKBR2), and CCR3 (CMKBR3) cluster ... Recently it was found that CCRL2 also acts as a receptor for the chemokine chemerin. This gene encodes a chemokine receptor ... Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the ... The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located. ...https://en.wikipedia.org/wiki/CCRL2
Comparison of the Gene Coding Contents and Other Unusual Features of the GC-Rich and AT-Rich Branch Probosciviruses | mSphere
The EEHV4 versions of U12 and U51 also match at about the same level to a subset of cellular alpha- or beta-chemokine receptors ... The arrow denotes two mammalian host cell chemokine receptors, CCR1 (Bov) and CCR3 (Lox), that are likely to exemplify or ... Identification and characterization of a spliced C-type lectin-like gene encoded by rat cytomegalovirus. J Virol 75:603-611. ... vGPCR and chemokine receptor family proteins compared to key human representatives of all genera within the mammalian beta- and ...http://msphere.asm.org/content/1/3/e00091-16
CCR2 - Wikipedia
Daugherty BL, Springer MS (April 1997). "The beta-chemokine receptor genes CCR1 (CMKBR1), CCR2 (CMKBR2), and CCR3 (CMKBR3) ... Samson M, Soularue P, Vassart G, Parmentier M (September 1996). "The genes encoding the human CC-chemokine receptors CC-CKR1 to ... CCR2 is a chemokine receptor. This CCR2 gene is located in the chemokine receptor gene cluster region. Two alternatively ... This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1 (CCL2), a chemokine which specifically ...https://en.wikipedia.org/wiki/CCR2
CCBP2 - Wikipedia
This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein- ... Comparison to three other related macrophage inflammatory protein-1alpha receptors, CCR-1, CCR-3, and CCR-5". J. Biol. Chem. ... This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. GRCh38: Ensembl release ... the orphan chemokine receptor G protein-coupled receptor-2 (GPR-2, CCR10) binds the skin-associated chemokine CCL27 (CTACK/ALP/ ...https://en.wikipedia.org/wiki/CCBP2
Aberrant in Vivo T Helper Type 2 Cell Response and Impaired Eosinophil Recruitment in Cc Chemokine Receptor 8 Knockout Mice |...
1999) HHV8-encoded vMIP-I selectively engages chemokine receptor CCR8. Agonist and antagonist profiles of viral chemokines. J. ... 1998) Identification of CCR8 as the specific receptor for the human beta-chemokine I-309cloning and molecular characterization ... 1999) The role of chemokines and chemokine receptors in T cell priming and Th1/Th2-mediated responses. Haematologica. 84:28-31 ... Gene Targeting.. A 1.2-kb BglII DNA fragment of the mCCR8 gene containing the 5′ region of homology, and a 6.5-kb BglII-HindIII ...http://jem.rupress.org/content/193/5/573
Cell lines expressing recombinant aequorin and a G-protein coupled receptor for functional screening ( INTRODUCTION ...
... receptor,for,functional,screening,biological,advanced biology technology,biology laboratory technology,biology device ... INTRODUCTION ...Many G-protein coupled receptors (GPCRs) trigger upon binding of an a...One of the methods of choice (reviewed ... Chemokine receptors: CCR1, CCR2, CCR3, CCR5, CCR6, CCR8, CXCR4 Corticotropin-releasing factor CRF2 Histamine H1 receptor ... Human chemokine CCR8 receptor: CHO cells expressing the chemokine CCR8 receptor were transfected with a plasmid encoding the G ...http://www.bio-medicine.org/biology-technology/Cell-lines-expressing-recombinant-aequorin-and-a-G-protein-coupled-receptor-for-functional-screening-1376-1/
Kinetics of gene expression and bone remodelling in the clinical phase of collagen-induced arthritis | Arthritis Research &...
CCL9/MIP-1gamma and its receptor CCR1 are the major chemokine ligand/receptor species expressed by osteoclasts. J Cell Biochem ... Differentially expressed genes related to the BMP pathway included the genes encoding the BMP type I and type II receptors ( ... in addition to minor expression changes in the genes of some of the transforming growth factor beta (TGFβ) receptors (Acvr2a ... Group 1: genes encoding proteins involved in osteoclast function and differentiation; Group 2: genes encoding proteins with a ...https://arthritis-research.biomedcentral.com/articles/10.1186/s13075-015-0531-7
CCL5 - C-C motif chemokine - Sus scrofa (Pig) - CCL5 gene & protein
... help/gene_ontology' target='_top'>More...,/a>,/p>GO - Molecular functioni. *CCR1 chemokine receptor binding Source: Ensembl ... R-SSC-380108. Chemokine receptors bind chemokines. R-SSC-418594. G alpha (i) signalling events. ... Belongs to the intercrine beta (chemokine CC) family.UniRule annotation. ,p>Information which has been generated by the ... br>,/br>The component name refers to the genomic component encoding a set of proteins. ,br>,/br>These range from a single ...http://www.uniprot.org/uniprot/Q2EN89
CCR8 (gene) - Wikipedia
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein ... This gene is located at the chemokine receptor gene cluster region. CC chemokine receptors GRCh38: Ensembl release 89: ... Howard OM, Dong HF, Shirakawa AK, Oppenheim JJ (2000). "LEC induces chemotaxis and adhesion by interacting with CCR1 and CCR8 ... "The assignment of chemokine-chemokine receptor pairs: TARC and MIP-1 beta are not ligands for human CC-chemokine receptor 8". ...https://en.wikipedia.org/wiki/CCR8_(gene)
CCL5 - Wikipedia
Chemokine (C-C motif) ligand 5 (also CCL5) is a protein which in humans is encoded by the CCL5 gene. It is also known as RANTES ... CCL5 has been shown to interact with CCR3, CCR5 and CCR1. CCL5 also activates the G-protein coupled receptor GPR75. Chemotaxis ... binding capacities of natural LD78beta isoforms of macrophage inflammatory protein-1alpha to the CC chemokine receptors 1, 3 ... and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells". Science. 270 (5243): 1811-5. doi:10.1126/science ...https://en.wikipedia.org/wiki/CCL5
Temporal expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight...
... chemokine receptor genes [22, 25, 26], function-blocking antibodies  or receptor antagonists [28, 29], to demonstrate a non ... Preparation of radioactively labelled cRNA probes encoding the CCR1, CCR2 and CCR5 receptors was carried out as previously ... Simpson JE, Newcombe J, Cuzner ML, Woodroofe MN: Expression of monocyte chemoattractant protein-1 and other beta-chemokines by ... Chemokines act as ligands on a subgroup of G-protein coupled seven transmembrane domain receptors called chemokine receptors [ ...https://jneuroinflammation.biomedcentral.com/articles/10.1186/1742-2094-4-14
Inhibition of hypothalamic leukemia inhibitory factor exacerbates diet-induced obesity phenotype | Journal of Neuroinflammation...
Using a real-time PCR array, we identified leukemia inhibitory factor as a chemokine/cytokine undergoing a rapid increase in ... The objective of this study was to identify chemokine-related transcripts that could be involved in the early stages of diet- ... This is a 96-gene panel, with 84 genes for chemokine/chemokine receptors and the remaining for endogenous and positive controls ... Ccl20 encodes for the CCL20 protein, also known as liver activation-regulated chemokine (LARC) . Its expression can be ...https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-017-0956-9
Herpesvirus-Encoded G Protein-Coupled Receptors as Modulators of Cellular Function | Molecular Pharmacology
GaoJL and Murphy PM (1994) Human cytomegalovirus open reading frame US28 encodes a functional beta chemokine receptor. J Biol ... HHV-6-Encoded U51 Contributes to Immune Evasion. Similar to the HCMV-encoded US28 receptor, the HHV-6-encoded U51 gene was ... The first nonpeptidergic compound, VUF2274, was derived from an antagonist against the chemokine receptor CCR1 (Casarosa et al ... Herpesviruses have acquired several genes encoding chemokine receptors into their genome. Both chemokine binding and the ...http://molpharm.aspetjournals.org/content/76/4/692
A database of human genes and a gene network involved in response to tick-borne encephalitis virus infection | BMC Evolutionary...
... proinflammation and tissue damage pathway triggered by chemokine receptor CCR5 interacting with CD4, CCL3, CCL4, CCL2. Among ... Genes were ranked according to the number of interactions in the network. Two genes/proteins (CCR5 and IFNAR1) that had maximal ... The aims of the study were to compile a catalog of human genes involved in response to TBEV infection and to rank genes from ... three genes/proteins (CCR5, IL10, ARID1B) were found to have protein-protein interactions within the network, and two genes/ ...https://bmcevolbiol.biomedcentral.com/articles/10.1186/s12862-017-1107-8
C-C chemokine receptor type 6 - Wikipedia
... a new human gene encoding a G-protein-coupled receptor related to chemokine receptors and located on chromosome 6q27". Genomics ... Linking antimicrobial and CC chemokine receptor-6-binding activities with human beta-defensins". J. Biol. Chem. 277 (40): 37647 ... Chemokine receptor 6 also known as CCR6 is a CC chemokine receptor protein which in humans is encoded by the CCR6 gene. CCR6 ... chemokine receptor activity. • receptor activity. • protein binding. • C-C chemokine receptor activity. • C-C chemokine binding ...https://en.wikipedia.org/wiki/C-C_chemokine_receptor_type_6
005427 - B6.129P2-Ccr5|tm1Kuz|/J
... receptor 5 in these knock-out mice affects immune and a number of other physiological responses. They are useful for widespread ... Gene Symbol and Name. Ccr5, chemokine (C-C motif) receptor 5. Gene Synonym(s). CC-CKR-5; CCCKR5; CCR-5; CD195; CKR-5; CKR5; ... Chemokine receptor CCR1 disruption limits renal damage in a murine model of hemolytic uremic syndrome. Am J Pathol 180(3):1040- ... CC chemokine receptor 5 signaling pathway in the neuroinflammatory response and cognitive deficits induced by beta-amyloid ...https://www.jax.org/strain/005427
Monocyte chemoattractant protein-2 ELISA | Chemokine (C-C motif) ligand 8 ELISA | Mouse CCL8/MCP-2 ELISA | CCL8 ELISA | MCP-2...
CCL8 acts through binding to several different cell surface chemokine receptors, including CCR1, CCR2B, and CCR5 (one of the ... is a protein encoded by the CCL8 gene. The precursor protein (109 amino acids) is cleaved to produce mature CCL8 (75 amino ... CAR Receptor Booster * Adenoviral Vector Systems * Adenoviral Expression System 3 * Adenoviral Expression System 3 (Tet-On 3G ... Human Beta-globin Control Primer Set * Human Papillomavirus PCR Detection Set * Human Papillomavirus PCR Typing Set ...http://www.clontech.com/US/Products/Cell_Biology_and_Epigenetics/Cytokines/CCL8_MCP-2?sitex=10020:22372:US&PEBCL1=VDNMfpAdaJW89oKgMaWJcEVzr7&PEBCL1_pses=ZG385BE8EC148BFAF12BFC39F963D5DC61682D187322B5FA54EA793FC396BFA083AA3BD1C11724EE452623A0187B94E1EC896013776EAB294B
Uterine Fibroids: Pathogenesis and Interactions with Endometrium and Endomyometrial Junction
Even chemokines and their receptors (MIP-1α, MIP-1β, RANTES, eotaxin, eotaxin-2, IL-8, CCR1, CCR3, CCR5, CXCR1, and CXCR2 mRNA ... This gene encodes a high mobility group DNA binding protein and embryonic proliferation modulator . The HMGA2 gene is ... H. Asada, Y. Yamagata, T. Taketani et al., "Potential link between estrogen receptor-α gene hypomethylation and uterine fibroid ... Q. Qiao, M. Ramadani, S. Gansauge et al., "Reduced membranous and ectopic cytoplasmic expression of beta-catenin correlate with ...https://www.hindawi.com/journals/ogi/2013/173184/
The commonly used antimicrobial additive triclosan is a liver tumor promoter | PNAS
2000) Regulation of genes encoding NAD(P)H:quinone oxidoreductases. Free Radic Biol Med 29(3-4):254-262. ... 1998) Androstane metabolites bind to and deactivate the nuclear receptor CAR-beta. Nature 395(6702):612-615. ... 2009) CCR1 and CCR5 promote hepatic fibrosis in mice. J Clin Invest 119(7):1858-1870. ... Through a reporter screening assay with an array of nuclear xenobiotic receptors (XenoRs), we found that TCS activates the ...http://www.pnas.org/content/111/48/17200