*  Interleukin 28 receptor, alpha subunit - Wikipedia
IL28RA is its human gene. The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms ... beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A ... alpha subunit is a subunit for the interleukin-28 receptor. ... IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The ... "Entrez Gene: IL28RA interleukin 28 receptor, alpha (interferon, lambda receptor)". ...
  https://en.wikipedia.org/wiki/Interleukin_28_receptor,_alpha_subunit
*  IL22RA1 - Wikipedia
Interleukin 22 receptor, alpha 1 is a protein that in humans is encoded by the IL22RA1 gene. The protein encoded by this gene ... beta (IL10RB/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 ... "Entrez Gene: Interleukin 22 receptor, alpha 1". Bleicher L, de Moura PR, Watanabe L, Colau D, Dumoutier L, Renauld JC, ... receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36. GRCh38: Ensembl release 89: ...
  https://en.wikipedia.org/wiki/IL22RA1
*  anti-IL22 Receptor alpha 1 antibody | GeneTex
... interleukin 22 receptor, alpha 1) for ELISA, ICC/IF, WB. Anti-IL22 Receptor alpha 1 pAb (GTX16978) is tested in Human samples. ... beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 ... interleukin 22 receptor, alpha 1. Background. The protein encoded by this gene belongs to the class II cytokine receptor family ... IL22 Receptor alpha 1 antibody See all IL22 Receptor alpha 1 products ...
  http://www.genetex.com/IL22-Receptor-antibody-GTX16978.html
*  IFNLR1 Gene - GeneCards | INLR1 Protein | INLR1 Antibody
Interferon Lambda Receptor 1, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The ... beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A ... Peginterferon alpha-2a/Peginterferon alpha-2b Pathway (Hepatocyte), Pharmacodynamics. Peginterferon alpha-2a/Peginterferon ... Entrez Gene Summary for IFNLR1 Gene. * The protein encoded by this gene belongs to the class II cytokine receptor family. This ...
  http://www.genecards.org/cgi-bin/carddisp.pl?id_type=entrezgene&id=163702
*  Warner Greene, MD, PhD | UCSF-Gladstone Center for AIDS Research (CFAR)
Regulation of interleukin 2 receptor alpha subunit (Tac or CD25 antigen) gene expression: binding of inducible nuclear proteins ... Contrasting interleukin 2 binding properties of the alpha (p55) and beta (p70) protein subunits of the human high-affinity ... Genes Dev. 1990 Jun; 4(6):1014-22. View on Pubmed * Fung MR, Greene WC. The human interleukin-2 receptor: insights into subunit ... Activation of the interleukin-2 receptor alpha gene: regulatory role for DNA-protein interactions flanking the kappa B enhancer ...
  http://cfar.ucsf.edu/people/warner-greene?qt-admin_staff_mgnt_profile_tabs=8
*  Frontiers | Regulation of Lung Epithelial Sodium Channels by Cytokines and Chemokines | Immunology
Interleukin-1beta decreases expression of the epithelial sodium channel alpha-subunit in alveolar epithelial cells via a p38 ... of beta2-adrenergic receptor-mediated alveolar epithelial fluid transport by interleukin-8 and transforming growth factor-beta ... Glucocorticoids can activate the alpha-ENaC gene promoter independently of SGK1. Biochem J (2009) 423:189-97. doi:10.1042/ ... The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2017.00766/full
*  CHUK - Wikipedia
Inhibitor of nuclear factor kappa-B kinase subunit alpha (IKK-α) also known as IKK1 or conserved helix-loop-helix ubiquitous ... lymphotoxin beta receptor, and CD40". J. Biol. Chem. 276 (18): 14602-6. doi:10.1074/jbc.C100103200. PMID 11278268. Ninomiya- ... "Entrez Gene: CHUK conserved helix-loop-helix ubiquitous kinase". Qiutang Li; Qingxian Lu; Jason Y. Hwang; Dirk Büscher; Kuo-Fen ... Windheim M, Stafford M, Peggie M, Cohen P (March 2008). "Interleukin-1 (IL-1) Induces the Lys63-Linked Polyubiquitination of IL ...
  https://en.wikipedia.org/wiki/CHUK
*  IL4R | Cancer Genetics Web
interleukin-4 receptor subunit alpha. Source:. NCBIAccessed: 11 March, 2017. Ontology:. What does this gene/protein do?. Show ( ... whereas IL-4 had no significant influence on alpha (CD25) and beta subunits (CD122) of IL-2R. Moreover, specific inhibitors, ... Ten normal bladder specimens demonstrated ≤ 1+ staining for IL-4Rα and IL-13Rα1 and no staining for IL-2RγC. These results ... This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and ...
  http://www.cancerindex.org/geneweb/IL4R.htm
*  Browse our IL29 ELISA Kits
Interleukin 20 Receptor beta ELISA Kits * Interleukin 20 Receptor alpha ELISA Kits ... This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine ... STAT2 (show STAT2 ELISA Kits) recruits USP18 (show USP18 ELISA Kits) to the type I IFN receptor subunit IFNAR2 (show IFNAR2 ... The review focuses on the value of the type I and III interferon (show IFNA ELISA Kits) subtypes (alphas, beta and lambdas) as ...
  https://www.antibodies-online.com/abstract/Interleukin+29+
*  Interleukin - Wikipedia
Interleukin 12 (IL-12) is a disulphide-bonded heterodimer consisting of a 35kDa alpha subunit and a 40kDa beta subunit. It is ... The receptors can both bind all three forms of IL-1 (IL-1 alpha, IL-1 beta and IL-1 receptor antagonist). The crystal ... "Constitutive synthesis of interleukin-3 by leukaemia cell line WEHI-3B is due to retroviral insertion near the gene". Nature. ... Interleukin 1 alpha and interleukin 1 beta (IL1 alpha and IL1 beta) are cytokines that participate in the regulation of immune ...
  https://en.wikipedia.org/wiki/Interleukin
*  IKK2 - Wikipedia
... kinase beta) gene. IKK-β is an enzyme that serves as a protein subunit of IκB kinase, which is a component of the cytokine- ... lymphotoxin beta receptor, and CD40". J. Biol. Chem. 276 (18): 14602-6. doi:10.1074/jbc.C100103200. ISSN 0021-9258. PMID ... Windheim M, Stafford M, Peggie M, Cohen P (March 2008). "Interleukin-1 (IL-1) Induces the Lys63-Linked Polyubiquitination of IL ... NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK". Science. 278 (5339): 866-9. doi:10.1126/science. ...
  https://en.wikipedia.org/wiki/IKK2
*  Index of immunology articles - Wikipedia
... beta subunit Interleukin 12 Interleukin 12 subunit beta Interleukin 13 Interleukin 16 Interleukin 2 Interleukin 20 receptor, ... alpha Interleukin 8 receptor, beta Interleukin receptor Interleukin-1 receptor Interleukin-1 receptor family Interleukin-1 ... gene) CCR4 CCR5 CCR8 (gene) CCR9 CCRL1 CCRL2 CD117 CD32B CD4 CD4+ T cells and antitumor immunity CD74 CD94/NKG2 Cell-mediated ... alpha subunit Interleukin 34 Interleukin 35 Interleukin 6 Interleukin 7 Interleukin 7 receptorInterleukin 8 Interleukin 8 ...
  https://en.wikipedia.org/wiki/Index_of_immunology_articles
*  A systematic study of modulation of ADAM-mediated ectodomain shedding by site-specific O-glycosylation | PNAS
Interleukin-6 receptor subunit alpha (IL6-RA), Tumor necrosis factor receptor superfamily member 1B (TNF-R2), IFN alpha/beta ... Precise Gene Edited Cell Models.. We further knocked out GALNT2 and GALNT3 in HEK293 using the same procedures. ZFN targeting ... Ten out of 12 peptides were cleaved in vitro by one or more ADAM isoforms and, among the corresponding glycopeptides, 8 of 10 ... it was shown that mutational loss of O-glycosylation in the stem region of the Interleukin-2 receptor subunit alpha (IL2Rα) ...
  http://www.pnas.org/content/112/47/14623
*  IL-28 R alpha/IFN-lambda R1 Antibody (NBP1-84381): Novus Biologicals
Rabbit Polyclonal Anti-IL-28 R alpha/IFN-lambda R1 Antibody. Validated: ICC/IF, IHC, IHC-P. Tested Reactivity: Human. 100% ... alpha. *interleukin or cytokine receptor 2. *interleukin-28 receptor subunit alpha ... Discover related pathways, diseases and genes to IL-28 R alpha/IFN-lambda R1 Antibody (NBP1-84381). Need help? Read the ... Expression of Type-III interferons (IFNlambdas) and their receptor in Sjogren's Syndrome. Clin. Exp. Immunol. Sep 10 2016 [PMID ...
  https://www.novusbio.com/products/il-28-r-alpha-ifn-lambda-r1-antibody_nbp1-84381
*  Oncostatin M - Wikipedia
All beta receptor subunits of the gp130 system also possess a box 3 region. This region corresponds to the C-terminal amino ... "Separate signaling mechanisms are involved in the control of STAT protein activation and gene regulation via the interleukin 6 ... "Distinct roles for leukemia inhibitory factor receptor alpha-chain and gp130 in cell type-specific signal transduction". J. ... specific receptor but not leukemia inhibitory factor/OM receptor or interleukin-6 receptor. Complete block of OM-induced KS ...
  https://en.wikipedia.org/wiki/Oncostatin_M
*  MAP3K14 - Wikipedia
... lymphotoxin beta receptor, and CD40". J. Biol. Chem. 276 (18): 14602-6. doi:10.1074/jbc.C100103200. PMID 11278268. Régnier CH, ... family and to the interleukin-1 type-I receptor. MAP3K14 has been shown to interact with: CHUK, IKK2, and TRAF2. ... is an enzyme that in humans is encoded by the MAP3K14 gene. This gene encodes mitogen-activated protein kinase kinase kinase 14 ... NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK". Science. 278 (5339): 866-9. doi:10.1126/science. ...
  https://en.wikipedia.org/wiki/MAP3K14
*  Ubiquitin C - Wikipedia
UBC gene differs from UBB gene in the number of Ub coding units they contain. Nine to ten Ub units were in the UBC gene. In ... "Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB ... "Interaction of heat-shock protein 90 beta isoform (HSP90 beta) with cellular inhibitor of apoptosis 1 (c-IAP1) is required for ... Kawahara K, Hashimoto M, Bar-On P, Ho GJ, Crews L, Mizuno H, Rockenstein E, Imam SZ, Masliah E (March 2008). "alpha-Synuclein ...
  https://en.wikipedia.org/wiki/Ubiquitin_C
*  Interleukin-22 is increased in multiple sclerosis patients and targets astrocytes | Journal of Neuroinflammation | Full Text
Identification of the IL-22 receptor subunit, IL-22R1, was performed by immunohistochemistry and immunofluorescence in human ... Furthermore, polymorphism between MS patients and controls has been recently described in the gene coding for IL-22 binding ... Using immunohistochemistry and confocal microscopy, we found that IL-22 and its receptor were detected on astrocytes of brain ... interleukin-22 (IL-22), a Th17-linked cytokine, has been implicated in blood brain barrier breakdown and lymphocyte ...
  https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-015-0335-3
*  Interleukin 10 - Wikipedia
... alpha subunit. The receptor complex for IL-10 also requires the IL10R2 chain to initiate signalling. This ligand-receptor ... "Entrez Gene: IL10 interleukin 10". Braat H, Rottiers P, Hommes DW, Huyghebaert N, Remaut E, Remon JP, van Deventer SJ, Neirynck ... IFN-alpha, -beta, -epsilon, -kappa, -omega), type-II (IFN-gamma) and type-III (IFN-lambda, also known as IL-28A, IL-28B, and IL ... Ho AS, Liu Y, Khan TA, Hsu DH, Bazan JF, Moore KW (December 1993). "A receptor for interleukin 10 is related to interferon ...
  https://en.wikipedia.org/wiki/Interleukin_10
*  Cytokines and Transcription Factors That Regulate T Helper Cell Differentiation: New Players and New Insights | SpringerLink
A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits. Proc Natl Acad Sci USA 93 ... A lineage-restricted transcription factor that regulates the expression of the T cell receptor alpha gene. EMBO J 10(5):1187- ... Kondo N, Matsui E, Kaneko H, et al.: Atopy and mutations of IL-12 receptor beta 2 chain gene. Clin Exp Allergy 31(8):1189-1193 ... Smeltz RB, Chen J, Hu-Li J, Shevach EM: Regulation of interleukin (IL)-18 receptor alpha chain expression on CD4(+) T cells ...
  https://link.springer.com/article/10.1023%2FA%3A1023381027062
*  Frontiers | Metabolic Reprograming of Mononuclear Phagocytes in Progressive Multiple Sclerosis | Immunology
HIFs are heterodimeric proteins composed of a constitutively expressed beta subunit and an oxygen-dependent alpha subunit (HIF- ... interleukin; IFN-γ, interferon-γ; TCA, citric acid cycle; TLR, Toll-like receptor. ... Immunoresponsive gene 1 (Irg1) protein is the enzyme responsible for the production of ITA in mammalian cells. Gene silencing ... By expressing pattern recognition receptors, including toll-like receptors (TLRs) and NOD-like receptors (NLRs), MPs can sense ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2015.00106/full
*  EXBIO Antibodies Product Data Sheet
CD25 (IL2Ralpha, Tac) is a ligand-binding alpha subunit of interleukin 2 receptor (IL2R). Together with beta and gamma subunit ... Eugene, OR 97402, USA, Tel: (541) 465-8300. Fax: (541) 335-0504. ... Interleukin-2 receptor alpha chain), a 55 kDa type I ... Lai KN, Leung JC, Lai FM: Soluble interleukin 2 receptor release, interleukin 2 production, and interleukin 2 receptor ... The interleukin-2 receptor in human monocytes and macrophages: regulation of expression and release of the alpha and beta ...
  http://www.exbio.cz/pdf/data_sheet_new.py/CLO000000000000028/26/6/datasheet-PB-218-T100.html?format=html
*  Therapeutic application of isolated naturally-occuring soluble truncated forms of IL-23 receptor - Patent application
A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits. Proc Natl Acad Sci USA. ... forms of the human interleukin-23 receptor alpha chain in mitogen-activated leukocytes. Genes Immun. 2008; 9:631-639. [0280] 27 ... Plasma from ten (10) Crohn's patients was obtained from Asterand. [0240] Biochemical Properties of Δ9 Protein [0241] Culture ... refers to interleukin-23 receptor. IL-23R is composed of two (2) subunits: IL-23Rα and IL-12Rβ1. The IL-23Rα gene is located on ...
  http://www.patentsencyclopedia.com/app/20120071422
*  Psoriasis - Wikipedia
Two major immune system genes under investigation are interleukin-12 subunit beta (IL12B) on chromosome 5q, which expresses ... which expresses the interleukin-23 receptor, and is involved in T cell differentiation. Interleukin-23 receptor and IL12B have ... When infliximab no longer binds tumor necrosis factor alpha, it no longer decreases inflammation, and psoriasis may worsen. ... Interleukin-23 is known to induce the production of interleukin-17 and interleukin-22. Interleukin-22 works in combination with ...
  https://en.wikipedia.org/wiki/Psoriasis
*  Gemfibrozil, a Lipid Lowering Drug, Inhibits the Activation of Primary Human Microglia Via Peroxisome Proliferator-Activated...
Increased peroxisomal fatty acid beta-oxidation and enhanced expression of peroxisome proliferator-activated receptor-alpha in ... Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross ... Jana M, Pahan K (2009) Induction of lymphotoxin-alpha by interleukin-12 p40 homodimer, the so-called biologically inactive ... BCL-6 negatively regulates expression of the NF-kappaB1 p105/p50 subunit. J Immunol 174:205-214PubMedGoogle Scholar ...
  https://link.springer.com/article/10.1007%2Fs11064-012-0781-6