*  Galectin - Wikipedia
Galectins are a family of proteins defined by their binding specificity for β-galactoside sugars, such as N-acetyllactosamine ( ... There are no serious defects when individual galectin genes are deleted in knock-out mouse models. This is because there is ... Tandem galectins include galectin-4, -6, -8, -9 and -12. The final galectin is galectin-3 which is the only galectin found in ... It binds to adhesion proteins such as integrins and blocks further binding to other cells or the extracellular matrix. When ...
  https://en.wikipedia.org/wiki/Galectin
*  Lgals3 - Galectin-3 - Rattus norvegicus (Rat) - Lgals3 gene & protein
May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. In the nucleus: acts as ... Simple Modular Architecture Research Tool; a protein domain database. More...SMARTi. View protein in SMART. SM00908. Gal-bind_ ... Simple Modular Architecture Research Tool; a protein domain database. More...SMARTi. View protein in SMART. SM00908. Gal-bind_ ... Protein-protein interaction databases. STRING: functional protein association networks. More...STRINGi. 10116. ...
  http://www.uniprot.org/uniprot/P08699
*  Galectin-3 - Wikipedia
"Entrez Gene: LGALS3 lectin, galactoside-binding, soluble, 3". Liu FT, Patterson RJ, Wang JL (September 2002). "Intracellular ... Koths K, Taylor E, Halenbeck R, Casipit C, Wang A (July 1993). "Cloning and characterization of a human Mac-2-binding protein, ... Companies have developed galectin modulators that block the binding of galectins to carbohydrate structures. The galectin-3 ... Pecta-Sol C binds to galectin-3 binding sites on the surfaces of cells as a preventative measure created by Isaac Eliaz in ...
  https://en.wikipedia.org/wiki/Galectin-3
*  Galectin-3-binding protein ELISA | Human LGALS3BP ELISA | Mac-2bp ELISA
Electroporation of Cas9-sgRNA ribonucleoproteins (RNPs) for gene editing in diverse cell types ... Galectin proteins contain carbohydrate-recognition-binding domains (CRDs) that bind beta-galactoside sugars and are involved in ... Human Mac-2 Binding Protein (Mac-2bp) Assay Kit - IBL 96-Well $1,017.00 ... Human Galectin-3-binding protein ELISA. Galectin-3-binding protein (also known as LGALS3BP, Mac-2bp, or 90K) is a N- ...
  http://www.clontech.com/US/Products/Cell_Biology_and_Epigenetics/Cell_Adhesion_and_Extracellular_Matrix/Galectin-3?sitex=10020:22372:US&PEBCL1=VLEPFh7Mdl7opBauxkgsoB8I96&PEBCL1_pses=ZGBA2BF6594C3443A4EF078C272CF6E69E776C772C42F00223804777CEFEA668F9BE415A1C01503FFC42B93B65C373766D48F61CA7A67670D2
*  LGALS3BP - Wikipedia
The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds to galectin 1. ... "Entrez Gene: LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein". Rosenberg I, Cherayil BJ, Isselbacher KJ, ... The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions ... Sasaki T, Brakebusch C, Engel J, Timpl R (1998). "Mac-2 binding protein is a cell-adhesive protein of the extracellular matrix ...
  https://en.wikipedia.org/wiki/LGALS3BP
*  A Novel Function for Galectin-1 at the Crossroad of Innate and Adaptive Immunity: Galectin-1 Regulates Monocyte/Macrophage...
Galectins, a growing family of carbohydrate-binding proteins, have recently attracted the attention of immunologists as novel ... Normal development of mice carrying a null mutation in the gene encoding the L14 S-type lectin. Development 119: 1229-1236. ... Protein concentrations were determined using the microBCA protein assay (Pierce). Equal amounts of protein (60 μg) were then ... the magnitude of protein-glycan or protein-protein interactions, and the relative abundance of the monomeric or dimeric forms ...
  http://www.jimmunol.org/content/178/1/436
*  Protocols and Video Articles Authored by Niels Hammer
May, 2004 , Pubmed ID: 15121863 Insulin-like growth factor II mRNA-binding protein 1 (IMP1) belongs to a family of RNA-binding ... we generated IMP1-deficient mice carrying a gene trap insertion in the Imp1 gene. Imp1(-/-) mice were on average 40% smaller ... such as galectin- 1, lumican, tenascin-C, procollagen transcripts, and the Hsp47 procollagen chaperone. Taken together, the ... Dwarfism and Impaired Gut Development in Insulin-like Growth Factor II MRNA-binding Protein 1-deficient Mice Molecular and ...
  https://www.jove.com/author/Niels_Hammer
*  Method for eliciting an immune response to human telomerase reverse transcriptase - Patent # 8709995 - PatentGenius
... the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for ... "Oxytricha telomere-binding protein: separable DNA-binding and dimerization domains of the .alpha.-subunit," Genes and ... Hirashima, M. "Ecalectin/galectin-9, a novel eosinophil chemoattractant: Its function and production," Int. Arch. Allergy ... Gray, J.T. et al., "Cloning and expression of genes for the Oxytricha telomere-binding protein specific subunit interations in ...
  http://www.patentgenius.com/patent/8709995.html
*  Galectin-9 - Wikipedia
Galectin-9 is a protein that in humans is encoded by the LGALS9 gene. The galectins are a family of beta-galactoside-binding ... The protein encoded by this gene is an S-type lectin. This galectin is strongly overexpressed in Hodgkin's disease tissue and ... "Entrez Gene: LGALS9 lectin, galactoside-binding, soluble, 9 (galectin 9)". Hirashima M, Kashio Y, Nishi N, et al. (2004). " ... The protein has N- and C- terminal carbohydrate-binding domains connected by a link peptide. Multiple alternatively spliced ...
  https://en.wikipedia.org/wiki/Galectin-9
*  Mouse Galectin 3 ELISA Kit (ab113343) | Abcam
Abcam's Galectin 3 ELISA Kit suitable for Cell culture supernatant, Serum, Plasma in mouse. Reliably quantify 6 pg/ml of ... Laminin-binding protein. *Lectin L-29. *lectin, galactoside-binding, soluble, 3. *LGALS2 ... Proteins and Peptides. Proteomics tools. Agonists, activators, antagonists and inhibitors. Lysates. Multiplex miRNA assays. By ... Abcam's Galectin 3 Mouse ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the ...
  http://www.abcam.com/mouse-galectin-3-elisa-kit-ab113343.html
*  Gem-associated protein 2 - Wikipedia
2001). "SMN, the product of the spinal muscular atrophy gene, binds preferentially to dimethylarginine-containing protein ... 2001). "Association of galectin-1 and galectin-3 with Gemin4 in complexes containing the SMN protein". Nucleic Acids Res. 29 ( ... "Entrez Gene: SIP1 survival of motor neuron protein interacting protein 1". Mourelatos, Zissimos; Dostie Josée; Paushkin Sergey ... 2002). "Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins". J. Biol. Chem. 277 (7): 5631-6 ...
  https://en.wikipedia.org/wiki/Gem-associated_protein_2
*  Produktübersicht anti-CD6 Antikörper
Protein Überblick This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. ... The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated ... interaction of Galectin-1 (zeige LGALS1 Antikörper) and -3 with CD6 * upon T cell activation, SRSF1 (zeige SRSF1 Antikörper) ... The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to ...
  http://www.antikoerper-online.de/abstract/CD6+
*  Small nuclear ribonucleoprotein D1 - Wikipedia
This gene encodes a small nuclear ribonucleoprotein that belongs to the SNRNP core protein family. The protein may act as a ... a novel WD repeat protein component of the SMN complex that binds Sm proteins". The Journal of Biological Chemistry. 277 (7): ... Park JW, Voss PG, Grabski S, Wang JL, Patterson RJ (Sep 2001). "Association of galectin-1 and galectin-3 with Gemin4 in ... Sun D, Ou YC, Hoch SO (Apr 1997). "Analysis of genes for human snRNP Sm-D1 protein and identification of the promoter sequence ...
  https://en.wikipedia.org/wiki/Small_nuclear_ribonucleoprotein_D1
*  Hypoxia Modifies the Transcriptome of Primary Human Monocytes: Modulation of Novel Immune-Related Genes and Identification Of...
Of relevance are the aryl-hydrocarbon receptor (AHR), ARNT2, CCAAT enhancer-binding protein α (C/EBPα), CREB-binding protein ( ... and secreted proteins. Of note are galectin 8 (LGALS8), MMP-16 (MT3-MMP), MMP-19, regulator of G-protein signaling 1 (RGS1), ... Among modulated genes, 74 were known hypoxia-responsive genes, whereas the majority were new genes whose responsiveness to ... fatty acid binding protein 4 (FABP4, up-regulated), low density lipoprotein receptor (LDLR, down-regulated), oxysterol binding ...
  http://www.jimmunol.org/content/177/3/1941?ijkey=af87c72f3cb6191afe34bc3f179a2354ed4dae8b&keytype2=tf_ipsecsha
*  Galectin-1-Matured Human Monocyte-Derived Dendritic Cells Have Enhanced Migration through Extracellular Matrix | The Journal of...
... we noted that many of these genes encode proteins that participate in cell migration, such as actin binding and remodeling ... Identifying genes according to fold change revealed eight genes with mean fold change ,7 in galectin-1-treated MDDCs compared ... Genes were uploaded to the GOstat website to find statistically overrepresented gene ontologies within the group of genes (32 ... 8 genes) and 2412 genes with false discovery rate of 0.5% (13 genes), respectively. Hierarchical clustering was also performed ...
  http://www.jimmunol.org/content/177/1/216
*  ORBi: Browsing ORBi
Galectins constitute a gene family of beta-galactoside-specific lectins that show high homology in their carbohydrate-binding ... Galectins constitute a gene family of beta-galactoside-specific lectins that show high homology in their carbohydrate-binding ... Galectins: a family of animal beta-galactoside-binding lectins.. Barondes, S. H.; Castronovo, Vincenzo ; Cooper, D. N. et al. ... Galectin-1 Modulates Human Melanoma Cell Adhesion to Laminin. van den Brule, F. A.; Buicu, C.; Baldet, M. et al. in Biochemical ...
  http://orbi.ulg.ac.be/browse?type=author&value=Cooper%2C+D.+N
*  PTPRK - Wikipedia
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Protein tyrosine phosphatases ... Kim YS, Jung JA, Kim HJ, Ahn YH, Yoo JS, Oh S, Cho C, Yoo HS, Ko JH (2011). "Galectin-3 binding protein promotes cell motility ... PTPkappa only mediates binding between cells expressing PTPkappa (i.e. homophilic), and will not mediate cell aggregation ... Receptor-type tyrosine-protein phosphatase kappa is an enzyme that in humans is encoded by the PTPRK gene. PTPRK is also known ...
  https://en.wikipedia.org/wiki/PTPRK
*  LGALS13 - Wikipedia
Galactoside-binding soluble lectin 13 or placental protein 13 (PP13) is a protein that in humans is encoded by the LGALS13 gene ... "Entrez Gene: LGALS13 lectin, galactoside-binding, soluble, 13 (galectin 13)". Huppertz B, Meiri H, Gizurarson S, Osol G, Sammar ... galectin-13)". Protein Eng. 14 (11): 875-80. doi:10.1093/protein/14.11.875. PMID 11742106. Sjölinder M, Uhlmann J, Ponstingl H ... The protein encoded by this gene has lysophospholipase activity. It is composed of two identical subunits which are held ...
  https://en.wikipedia.org/wiki/LGALS13
*  Galectin-7 - Wikipedia
Galectin-7 is a protein that in humans is encoded by the LGALS7 gene. The galectins are a family of beta-galactoside-binding ... "Entrez Gene: LGALS7 lectin, galactoside-binding, soluble, 7 (galectin 7)". Bonaldo MF, Lennon G, Soares MB (1997). " ... 2006). "Galectin 7 (p53-induced gene 1): a new prognostic predictor of recurrence and survival in stage IV hypopharyngeal ... 2003). "Homodimeric galectin-7 (p53-induced gene 1) is a negative growth regulator for human neuroblastoma cells". Oncogene. 22 ...
  https://en.wikipedia.org/wiki/Galectin-7
*  Galectin-2 - Wikipedia
The protein encoded by this gene is a soluble beta-galactoside binding lectin. The encoded protein is found as a homodimer and ... Galectin-2 is a protein that in humans is encoded by the LGALS2 gene. ... "Entrez Gene: LGALS2 lectin, galactoside-binding, soluble, 2". Gitt MA, Massa SM, Leffler H, Barondes SH (1992). "Isolation and ... A single nucleotide polymorphism in an intron of this gene can alter the transcriptional level of the protein, with a resultant ...
  https://en.wikipedia.org/wiki/Galectin-2
*  Jurkat, Clone E6-1 ATCC ® TIB-152™ Homo sapiens peripheral b
Expression of galectin-3 modulates T-cell growth and apoptosis. Proc. Natl. Acad. Sci. USA 93: 6737-6742, 1996. PubMed: 8692888 ... Octamer binding factors and their coactivator can activate the murine PU.1 (spi-1) promoter. J. Biol. Chem. 271: 15743-15752, ... August A, Dupont B. Association between mitogen-activated protein kinase and the zeta chain of the T cell receptor (TcR) with ... Isolation of the human PC6 gene encoding the putative host protease for HIV-1 gp160 processing in CD4+ T lymphocytes. Proc. ...
  https://atcc.org/products/all/TIB-152.aspx
*  CLC (gene) - Wikipedia
It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be ... "The genomic structure of the human Charcot-Leyden crystal protein gene is analogous to those of the galectin genes". Genomics. ... "Entrez Gene: CLC Charcot-Leyden crystal protein". Human CLC genome location and CLC gene details page in the UCSC Genome ... The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes ...
  https://en.wikipedia.org/wiki/CLC_(gene)
*  ST2 cardiac biomarker - Wikipedia
The ST2 cardiac biomarker is a protein biomarker of cardiac stress encoded by the IL1RL1 gene. ST2 signals the presence and ... and a membrane-bound receptor form (referred to as the ST2 receptor or ST2L). When the myocardium is stretched, the ST2 gene is ... and galectin-3. One study indicated that discrimination is independent of age, body mass index, history of heart failure, ... The ST2 protein has two isoforms and is directly implicated in the progression of cardiac disease: a soluble form (referred to ...
  https://en.wikipedia.org/wiki/ST2_cardiac_biomarker
*  Galectin-3 Deficiency Accelerates High-Fat Diet-Induced Obesity and Amplifies Inflammation in Adipose Tissue and Pancreatic...
Deletion of Protein Kinase D1 in Pancreatic Beta Cells Impairs Insulin Secretion in High-Fat Fed Mice ... a galactoside-binding lectin, accelerates high-fat diet-induced obesity and diabetes. Obese LGALS3−/− mice have increased body ... a family of transcription factors that regulate the expression of proinflammatory genes upon cell stimulation with various ... Galectin-3 (Gal-3; also known as Mac-2), a 30-kDa β-galactoside-binding lectin, mainly located in the cytoplasm, but also in ...
  http://diabetes.diabetesjournals.org/content/62/6/1932.long
*  Introduction to galectins | SpringerLink
Good evidence suggest roles of galectins in cancer, immunity and inflammation, and development, but a unifying picture of their ... Hughes RC, Secretion of the galectin family of mammalian carbohydrate-binding proteins, Biochim Biophys Acta 1473, 172- 85 ( ... Chiariotti L, Salvatore P, Frunzio R, Bruni CB, Galectin genes: Regulation of expression, Glycoconjugate Journal 19, 441-449 ( ... Fred Brewer C, Binding and cross-linking properties of galectins, Biochim Biophys Acta 1572, 255-62 (2002).Google Scholar ...
  https://link.springer.com/article/10.1023%2FB%3AGLYC.0000014072.34840.04