*  C5a-dependent secretion of IL-6. The reverse passive Ar | Open-i
C5a-dependent secretion of IL-6. The reverse passive Arthus reaction (IC) was allowed to proceed for 4 or 8 h in C5aR (−/−) ... We recently demonstrated that gene-targeted disruption of the C5a anaphylatoxin receptor prevented lung injury in immune ... We recently demonstrated that gene-targeted disruption of the C5a anaphylatoxin receptor prevented lung injury in immune ... Impaired inflammatory responses in the reverse arthus reaction through genetic deletion of the C5a receptor. ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2199021_JEM.970777f3&req=4
*  PMN infiltration in the reverse Arthus reaction in the | Open-i
Bottom Line: We recently demonstrated that gene-targeted disruption of the C5a anaphylatoxin receptor prevented lung injury in ... Bottom Line: We recently demonstrated that gene-targeted disruption of the C5a anaphylatoxin receptor prevented lung injury in ... We recently demonstrated that gene-targeted disruption of the C5a anaphylatoxin receptor prevented lung injury in immune ... We recently demonstrated that gene-targeted disruption of the C5a anaphylatoxin receptor prevented lung injury in immune ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2199021_JEM.970777f4&req=4
*  C5ar1 - PrimePCR Assay and Template | Life Science | Bio-Rad
... templates for your target gene. Every primer pair is optimized, experimentally validated, and performance guaranteed. ... C5a anaphylatoxin chemotactic receptor Assay Type: Probe Assay Design: exonic Application: Gene Expression Unique Assay ID: ... C5a anaphylatoxin chemotactic receptor Assay Type: Probe Application: Gene Expression Unique Assay ID: dRnoCPE5147104 Info: FAM ... C5a anaphylatoxin chemotactic receptor Assay Type: Probe Application: Gene Expression Unique Assay ID: dRnoCPE5147105 Info: HEX ...
  http://www.bio-rad.com/en-us/prime-pcr-assays/gene/c5ar1-rat
*  GPR77 - Wikipedia
G protein-coupled receptor 77, is a protein that in humans is encoded by the C5AR2 gene. The anaphylatoxins C3a, C4a, and C5a ... 2004). "C5a mutants are potent antagonists of the C5a receptor (CD88) and of C5L2: position 69 is the locus that determines ... C5a anaphylatoxin chemotactic receptor C5a2 also known as C5L2, ... Complement peptide C5a, C4a, and C3a receptors". Pharmacol. Rev ... Cain SA, Monk PN (2002). "The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg ...
  https://en.wikipedia.org/wiki/GPR77
*  P2RY14 - Wikipedia
"Entrez Gene: P2RY14 purinergic receptor P2Y, G-protein coupled, 14". Gerard C, Gerard NP (1994). "C5A anaphylatoxin and its ... The product of this gene, P2Y14 belongs to the family of G-protein coupled receptors, which contains several receptor subtypes ... 2003). "Characterization of the UDP-glucose receptor (re-named here the P2Y14 receptor) adds diversity to the P2Y receptor ... 2003). "P2Y-like receptor, GPR105 (P2Y14), identifies and mediates chemotaxis of bone-marrowhematopoietic stem cells". Genes ...
  https://en.wikipedia.org/wiki/P2RY14
*  C5R1 purified MaxPab mouse polyclonal antibody (B01P) - (H00000728-B01P) - Products - Abnova
Gene Ontology:. *Hyperlink. *Other Designations:. *C5a anaphylatoxin receptor,C5a ligand,complement component 5 receptor 1 ...
  http://www.abnova.com/products/products_detail.asp?catalog_id=H00000728-B01P
*  GPR77 Antibody
C5a anaphylatoxin chemotactic receptor 2; C5a anaphylatoxin chemotactic receptor C5L2; C5L2; Complement component 5a receptor 2 ... Entrez Gene ID: (Human) 27202 Molecular Function: G-protein coupled receptor receptor ... G protein-coupled receptor 77; G protein-coupled receptor C5L2; G-protein coupled receptor 77; GPF77 ... chemotaxis inflammatory response G-protein coupled receptor signaling pathway regulation of complement activation negative ...
  https://www.thermofisher.com/antibody/product/C5L2-Antibody-Polyclonal/PA5-21307
*  C5a receptor - Wikipedia
"Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors ... "Anaphylatoxin Receptors: C5a". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical ... "Human chemotaxis receptor genes cluster at 19q13.3-13.4. Characterization of the human C5a receptor gene". Biochemistry. 32 (5 ... is a G protein-coupled receptor for C5a. It functions as a complement receptor. C5a receptor modulates inflammatory responses, ...
  https://en.wikipedia.org/wiki/C5a_receptor
*  C5a receptor - Wikipedia
"Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors ... "Anaphylatoxin Receptors: C5a". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical ... 1993). "Human chemotaxis receptor genes cluster at 19q13.3-13.4. Characterization of the human C5a receptor gene.". ... C5a receptor (receptor 1 komplementne komponente 5a, C5AR1, CD88, klaster diferencijacije 88) je G protein spregnuti receptor ...
  https://sh.wikipedia.org/wiki/C5a_receptor
*  Identification of candidate genes linking systemic inflammation to atherosclerosis; results of a human in vivoLPS infusion...
Differential expression of key genes was confirmed by RT-PCR and results were compared to in vitro data obtained by our group ... Such differentially expressed genes in circulating monocytes would be strong candidates for further investigation in disease ... No genes were significantly differentially expressed following saline infusion. Comparison with results obtained in in vitro ... One hour after LPS infusion, 11 genes were identified as being differentially expressed; 1 down regulated and 10 up regulated. ...
  https://bmcmedgenomics.biomedcentral.com/articles/10.1186/1755-8794-4-64
*  Formyl peptide receptor 1 - Wikipedia
C5a) and GPR77, a second C5a anaphylatoxin chemotactic receptor C5a2 (C5L2), a second C5a receptor of debated function which ... "Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors ... "Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors ... Formyl peptide receptor 1 (FPR1, FPR1 receptor, fMet-Leu-Phe receptor 1, FMLP receptor 1, or N-formylmethionyl-leucyl- ...
  https://en.wikipedia.org/wiki/Formyl_peptide_receptor_1
*  Anaphylatoxin - Wikipedia
Gerard, C; Gerard, N P (1994). "C5A Anaphylatoxin and Its Seven Transmembrane-Segment Receptor". Annual Review of Immunology. ... Gene Structure and Expression. 1443 (1-2): 90-8. doi:10.1016/S0167-4781(98)00198-5. PMID 9838061. Anaphylatoxin at the US ... Anaphylatoxins, or complement peptides, are fragments (C3a, C4a and C5a) that are produced as part of the activation of the ... Pan, Zhixing K. (1998). "Anaphylatoxins C5a and C3a induce nuclear factor κB activation in human peripheral blood monocytes". ...
  https://en.wikipedia.org/wiki/Anaphylatoxin
*  Anti-GPCR C5L2 antibody (ab77982) | Abcam
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a, C4a and C3a and their desarginated derivatives. ... Entrez Gene: 27202 Human. *Omim: 609949 Human. *SwissProt: Q9P296 Human. *Unigene: 534412 Human ... C5a and its receptors in human anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis.. Arthritis Res Ther 14:R140 ( ...
  http://www.abcam.com/gpcr-c5l2-antibody-ab77982.html
*  Latest technologies from Texas Portal
... complement anaphylatoxin C5a receptor-deficient mice on C57Black6 genetic background via the disruption of the C5aR gene. It is ... have developed complement anaphylatoxin C5a-deficient mice via the disruption of the C5aR gene. It is becoming increasingly ... C5a Receptor "Knock out" Mice The Technology: A researcher at the University of Texas Health Science Center at Houston ( ... C3a Receptor "Knock Out" Mice Market: Global sales of asthma and COPD treatments are currently worth around US$20 billion. In ...
  http://texas.technologypublisher.com/rss.aspx
*  Complement component 5 - Wikipedia
Oppermann M, Götze O (1995). "Plasma clearance of the human C5a anaphylatoxin by binding to leucocyte C5a receptors". ... 1995). "[Chemico-enzymatic synthesis, cloning and expression of a gene for an analog of human anaphylatoxin C5a]". Bioorg. Khim ... "Mitogen-activated protein kinase activation requires two signal inputs from the human anaphylatoxin C5a receptor". J. Biol. ... An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived ...
  https://en.wikipedia.org/wiki/Complement_component_5
*  Anti-C5aR/CD88 antibody (Biotin) [10/92] | Abcam
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme ... Entrez Gene: 12273 Mouse. *SwissProt: P30993 Mouse. *SwissProt: Q3TZ86 Mouse. *Unigene: 247623 Mouse ... Sulfation plays a critical role in the association of the receptor with C5a, but no significant role in the ability of the ... Clone 10/92 does not block the binding of the C5a to murine CD88. ... C5a anaphylatoxin chemotactic receptor antibody. *C5a ...
  http://www.abcam.com/c5r1-antibody-1092-biotin-ab54378.html
*  C3a receptor - Wikipedia
"In Xenopus oocytes the human C3a and C5a receptors elicit a promiscuous response to the anaphylatoxins". FEBS Letters. 395 (2-3 ... and chromosome localization of the mouse complement C3a anaphylatoxin receptor gene". Molecular Immunology. 35 (3): 137-48. doi ... "Anaphylatoxin Receptors: C3a". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical ... The C3a receptor also known as complement component 3a receptor 1 (C3AR1) is a G protein-coupled receptor protein involved in ...
  https://en.wikipedia.org/wiki/C3a_receptor
*  GNB1 - Wikipedia
"Mitogen-activated protein kinase activation requires two signal inputs from the human anaphylatoxin C5a receptor". J. Biol. ... This gene uses alternative polyadenylation signals. Click on genes, proteins and metabolites below to link to respective ... These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important ... Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 is a protein that in humans is encoded by the GNB1 gene. ...
  https://en.wikipedia.org/wiki/GNB1
*  Evolving Immunity
... into the gene for a primordial antigen-receptor gene, splitting it into two gene segments (V and J). The locus itself is ... Additionally, a C5a-like anaphylatoxin ability has been reported in hagfish (Newton, Raftos et al. 1994). The lytic pathway of ... Further gene duplications create additional V, D, and J gene segments, giving the receptors multiple rearrangement targets and ... such as the LPS receptor. Others include the glycan receptor, the mannose receptor, and the macrophage scavenger receptor; ...
  http://www.talkdesign.org/faqs/Evolving_Immunity1.2.html
*  CCR1 - Wikipedia
Gerard C, Gerard NP (1994). "C5A anaphylatoxin and its seven transmembrane-segment receptor". Annual Review of Immunology. 12 ( ... This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CXCR1, are found to form a gene cluster on ... This gene encodes a member of the beta chemokine receptor family, which belongs to G protein-coupled receptors. The ligands of ... C-C chemokine receptor type 1 is a protein that in humans is encoded by the CCR1 gene. CCR1 has also recently been designated ...
  https://en.wikipedia.org/wiki/CCR1
*  WikiGenes - Cloning, Molecular
C5A anaphylatoxin and its seven transmembrane-segment receptor. Gerard, C., Gerard, N.P. Annu. Rev. Immunol. (1994) [Pubmed] ... The CLAVATA1 gene encodes a putative receptor kinase that controls shoot and floral meristem size in Arabidopsis. Clark, S.E., ... The molecular cloning of the C5a receptor places this molecule in the superfamily of G-protein coupled receptors [8]. ... Hepatitis B virus DNA integration in a sequence homologous to v-erb-A and steroid receptor genes in a hepatocellular carcinoma. ...
  https://www.wikigenes.org/e/mesh/e/140.html
*  Evolving Immunity
... the RAG genes and flanked by RSSs integrates itself into the gene for a primordial antigen-receptor gene, splitting it into two ... Additionally, a C5a-like anaphylatoxin ability has been reported in hagfish (Newton, Raftos et al. 1994). The lytic pathway of ... such as the LPS receptor. Others include the glycan receptor, the mannose receptor, and the macrophage scavenger receptor; ... cell receptors. The steps of this model are based on comparisons between these genes and between those genes in different jawed ...
  http://www.talkdesign.org/faqs/Evolving_Immunity.html
*  3 78
Chenoweth D., Hugli . E. Demonstration of specific C5a and C5a analogs as probes of the neutrophil C5a receptor, Mol. Immunol ... N., Hugli . E. Primary structural analysis of the polypeptide portion of human C5a anaphylatoxin, J. Biol. Chem., 253, 6955 ... Susceptibility is controlled by the combination of H2 and histamine sensitization genes, J. Exp. Med., 155, 31 40 (1982). 316. ... Chenoweth D. E., Hugli . E. Demonstration of specific C5a receptor on intact human polymorphonuclear leukocytes, Proc. Natl. ...
  http://bio-cat.ru/ebook.php?file=paul_01_03.djvu&page=78
*  Formyl peptide receptor 3 - Wikipedia
"Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors ... Li R, Coulthard LG, Wu MC, Taylor SM, Woodruff TM (Mar 2013). "C5L2: a controversial receptor of complement anaphylatoxin, C5a ... "Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors ... to form a cluster which also includes the genes for another G protein-coupled chemotactic factor receptor, the C5a receptor ( ...
  https://en.wikipedia.org/wiki/Formyl_peptide_receptor_3
*  Human C5AR1/Galpha15 Stable Cell Line-Chem-1 - Creative Biogene
C5a is a potent chemotactic factor for huma ... Human complement C5a is a 74-amino acid glycopeptide generated ... C5a ligand); C5a anaphylatoxin chemotactic receptor; C5A; C5AR; CD88; C5a-R; C5a ligand; C5a anaphylatoxin receptor; complement ... DNA Methylation AnalysisPlasmid DNA Production ServiceGene Expression ServiceGene Synthesis and Cloning ServiceGene Mutagenesis ... C5a anaphylatoxin receptor activity; G-protein coupled receptor activity; receptor activity; signal transducer activity; ...
  https://www.creative-biogene.com/Human-C5AR1-Galpha15-Stable-Cell-Line-Chem-1-CSC-RG0614-195512-11.html