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*  Il11ra1 - Interleukin-11 receptor subunit alpha precursor - Rattus norvegicus (Rat) - Il11ra1 gene & protein
The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/ ... Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal ... help/gene_ontology' target='_top'>More...,/a>,/p>GO - Molecular functioni. *interleukin-11 binding Source: RGDInferred from ... help/gene_ontology' target='_top'>More...,/a>,/p>GO - Molecular functioni. *interleukin-11 binding Source: RGDInferred from ...
  http://www.uniprot.org/uniprot/Q99MF4
*  Interleukin 11 receptor alpha subunit - Wikipedia
IL11RA is its human gene. Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and ... alpha subunit is a subunit of the interleukin 11 receptor. ... "Entrez Gene: IL11RA interleukin 11 receptor, alpha". Chérel M, ... 1999). "Definition of receptor binding sites on human interleukin-11 by molecular modeling-guided mutagenesis". Eur. J. Biochem ... redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 ...
  https://en.wikipedia.org/wiki/Interleukin_11_receptor_alpha_subunit
*  Il31ra - Interleukin-31 receptor subunit alpha precursor - Mus musculus (Mouse) - Il31ra gene & protein
Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May ... Interleukin-31 receptor subunit alpha. 10. Q8K5B1-3. Q8K5B1-4. 547. UniRef90_Q8K5B1-3. Cluster: Isoform 3 of Interleukin-31 ... receptor subunit alpha. 2. Q8K5B1-4. Q8K5B1-3. 547. UniRef90_Q8K5B1-3. Cluster: Isoform 3 of Interleukin-31 receptor subunit ... Interleukin-31 receptor subunit alpha. 82. Q8K5B1-3. Q8K5B1-4. 547. UniRef50_Q8K5B1-3. Cluster: Isoform 3 of Interleukin-31 ...
  http://www.uniprot.org/uniprot/Q8K5B1
*  Interleukin 10 receptor, alpha subunit - Wikipedia
Interleukin 10 receptor, alpha subunit is a subunit for the interleukin-10 receptor. IL10RA, is its human gene. IL10RA has also ... Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Interleukin 10 receptor, alpha subunit ... "Entrez Gene: IL10RA interleukin 10 receptor, alpha". Ho AS, Liu Y, Khan TA, Hsu DH, Bazan JF, Moore KW (December 1993). "A ... The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors ...
  https://en.wikipedia.org/wiki/Interleukin_10_receptor,_alpha_subunit
*  Interleukin 15 receptor, alpha subunit - Wikipedia
Interleukin 15 receptor, alpha subunit is a subunit of the interleukin 15 receptor that in humans is encoded by the IL15RA gene ... The IL-15 receptor is composed of three subunits: IL-15R alpha, CD122, and CD132. Two of these subunits, CD122 and CD132, are ... "Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes". J. ... "IL-2 and IL-15 receptor alpha-subunits are coexpressed in a supramolecular receptor cluster in lipid rafts of T cells". Proc. ...
  https://en.wikipedia.org/wiki/Interleukin_15_receptor,_alpha_subunit
*  Interleukin 23 subunit alpha - Wikipedia
Interleukin-23 subunit alpha is a protein that in humans is encoded by the IL23A gene. IL-23 is produced by dendritic cells and ... "Genetic variations in the interleukin-12/interleukin-23 receptor (beta1) chain, and implications for IL-12 and IL-23 receptor ... "Entrez Gene: IL23A interleukin 23, alpha subunit p19". Parham C, Chirica M, Timans J, Vaisberg E, Travis M, Cheung J, et al. ( ... Interleukin-23 is a heterodimeric cytokine composed of an IL-12p40 subunit that is shared with IL-12 and the IL-23p19 subunit. ...
  https://en.wikipedia.org/wiki/Interleukin_23_subunit_alpha
*  Reactome | Interleukin-5 receptor alpha subunit binds Interleukin-5
More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology ... Interleukin-3, Interleukin-5 and GM-CSF signaling (Mus musculus) * Interleukin-5 receptor alpha subunit binds Interleukin-5 ( ... Interleukin-5 receptor alpha subunit binds Interleukin-5 Stable Identifier R-MMU-913456 ...
  http://www.reactome.org/content/detail/R-MMU-913456
*  Interleukin 5 receptor alpha subunit - Wikipedia
The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is ... Interleukin 5 receptor, alpha (IL5RA) also known as CD125 (Cluster of Differentiation 125) is a subunit of the Interleukin-5 ... Interleukin 5 receptor alpha subunit has been shown to interact with: Interleukin 5, Janus kinase 2, Protein unc-119 homolog, ... "Localization of the gene encoding the alpha subunit of human interleukin-5 receptor (IL5RA) to chromosome region 3p24-3p26". ...
  https://en.wikipedia.org/wiki/Interleukin_5_receptor_alpha_subunit
*  Diabetes mellitus, insulin-dependent, 10 - Conditions - GTR - NCBI
Summary: interleukin 2 receptor subunit alpha. Clinical features. HelpList of clinical features of the condition/phenotype ... Genes See tests for all associated and related genes. *Associated genes Help. Genes reported to contribute to the condition. ... Clinical tests (11 available). Molecular Genetics Tests. *Sequence analysis of the entire coding region (11) ...
  https://www.ncbi.nlm.nih.gov/gtr/conditions/C1866040/
*  IL4R | Cancer Genetics Web
VEGA, OMIM, HGNC, Ensembl, GeneCard, Gene. Protein:. interleukin-4 receptor subunit alpha. ... This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and ... Other two subunits of IL-4R, interleukin-13 receptor α1 (IL-13Rα1) and interleukin-2 receptor gamma (IL-2RγC), were either ... Here we investigate whether interleukin (IL)-4 receptor alpha (IL4Ralpha), a component of the receptor complex for the T helper ...
  http://www.cancerindex.org/geneweb/IL4R.htm
*  Warner Greene, MD, PhD | UCSF-Gladstone Center for AIDS Research (CFAR)
Regulation of interleukin 2 receptor alpha subunit (Tac or CD25 antigen) gene expression: binding of inducible nuclear proteins ... Genes Dev. 1990 Jun; 4(6):1014-22. View on Pubmed * Fung MR, Greene WC. The human interleukin-2 receptor: insights into subunit ... Activation of the interleukin-2 receptor alpha gene: regulatory role for DNA-protein interactions flanking the kappa B enhancer ... Induction of interleukin-2 receptor-alpha gene expression is regulated by post-translational activation of kappa B specific DNA ...
  https://cfar.ucsf.edu/people/warner-greene
*  CD126 (IL-6Rα) antibodies, human - Primary antibodies - Antibodies - MACS Flow Cytometry - Products - Miltenyi Biotec
Interleukin 6 (IL-6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important ... IL-6 binding to the receptor complex results in the stimulation of B and T cells, and hematopoietic precursor proliferation and ... It is also shared by many other receptors like leukemia inhibitory factor (LIF), ciliary neurotropic factor (CNTF), oncostatin ... Additional information: Clone REA291 displays negligible binding to Fc receptors. ...
  https://www.miltenyibiotec.com/UN-en/products/macs-flow-cytometry/antibodies/primary-antibodies/cd126-il-6ra-antibodies-human-rea291-1-11.html
*  humchr09.txt
HUMAN 118946 Ciliary neurotrophic factor receptor subunit alpha precursor (CNTF receptor subunit alpha) (CNTFR-alpha) CNTLN ... IL-11R subunit alpha) (IL-11R-alpha) (IL-11RA) IL33 9p24.1 O95760 IL33_HUMAN 608678 Interleukin-33 precursor (IL-33) ( ... RIG-I-like receptor 1) (RLR-1) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I ... PSE-binding factor subunit alpha) (PTF subunit alpha) (snRNA-activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit ...
  http://www.uniprot.org/docs/humchr09
*  Autoimmune Addison's Disease: Genetic Aetiology and Pathophysiology | Springer for Research & Development
Interleukin-2 and subunit alpha of its soluble receptor in autoimmune Addison's disease--an association study and expression ... Lack of association of the vitamin D receptor gene with Graves' disease in UK Caucasians. Clin Endocrinol. 2004;60(5):618-24. ... CIITA gene variants are associated with rheumatoid arthritis in Scandinavian populations. Genes Immun. 2012;13(5):431-6.PubMed ... NLRP1 gene polymorphism influences gene transcription and is a risk factor for rheumatoid arthritis in han chinese. Arthritis ...
  https://rd.springer.com/chapter/10.1007/978-3-319-62470-9_4
*  NFRKB - Wikipedia
... a novel DNA-binding protein that recognizes the interleukin-2 receptor alpha chain kappa B site". New Biol. 3 (11): 1063-73. ... "Entrez Gene: NFRKB nuclear factor related to kappaB binding protein". Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in ... Urban MB, Schreck R, Baeuerle PA (1991). "NF-kappa B contacts DNA by a heterodimer of the p50 and p65 subunit". EMBO J. 10 (7 ... Nuclear factor related to kappa-B-binding protein is a protein that in humans is encoded by the NFRKB gene. GRCh38: Ensembl ...
  https://en.wikipedia.org/wiki/NFRKB
*  A systematic study of modulation of ADAM-mediated ectodomain shedding by site-specific O-glycosylation | PNAS
Interleukin-6 receptor subunit alpha (IL6-RA), Tumor necrosis factor receptor superfamily member 1B (TNF-R2), IFN alpha/beta ... Precise Gene Edited Cell Models.. We further knocked out GALNT2 and GALNT3 in HEK293 using the same procedures. ZFN targeting ... it was shown that mutational loss of O-glycosylation in the stem region of the Interleukin-2 receptor subunit alpha (IL2Rα) ... 2007) Admixture mapping of an allele affecting interleukin 6 soluble receptor and interleukin 6 levels. Am J Hum Genet 80(4): ...
  http://www.pnas.org/content/112/47/14623
*  aminopterin: Topics by WorldWideScience.org
MMCH clones also expressed Toll-like receptors (TLRs) 1, 2, 4, and 6 and showed elevated levels of TNF-{alpha} expression in ... The established mouse mast cell hybridomas (MMCHs) expressed {alpha}, {beta}, and {gamma} subunits of high-affinity ... Change in number of copies of the DHFR gene in lines of such cells occurs through change in the number of DM, while size and ... Interleukin (IL)-3-dependent mouse bone marrow-derived mast cells (BMMCs) are an important model for studying the function of ...
  https://worldwidescience.org/topicpages/a/aminopterin.html
*  IL3RA - Wikipedia
Milatovich A, Kitamura T, Miyajima A, Francke U (1993). "Gene for the alpha-subunit of the human interleukin-3 receptor (IL3RA ... This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene ... The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is ... "Structure of the gene encoding the alpha subunit of the human interleukin 3 receptor". Biochem. Biophys. Res. Commun. 208 (1): ...
  https://en.wikipedia.org/wiki/IL3RA
*  KEGG PATHWAY: mmu04630
Il13ra2; interleukin 13 receptor, alpha 2 [KO:K05077]. 16169 Il15ra; interleukin 15 receptor, alpha chain [KO:K05074] ... Pik3ca; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [KO:K00922] [EC:2.7.1.153] ... Once activated, they dimerize and translocate to the nucleus and modulate the expression of target genes. In addition to the ... Pdgfra; platelet derived growth factor receptor, alpha polypeptide [KO:K04363] [EC:2.7.10.1] ...
  http://www.kegg.jp/entry/mmu04630
*  000646 - A/J
Gene Symbol and Name. Il3ra, interleukin 3 receptor, alpha chain. Gene Synonym(s). CD123; Cyrl; IL-3 receptor alpha chain; IL3R ... Impaired interleukin-3 (IL-3) response of the A/J mouse is caused by a branch point deletion in the IL-3 receptor alpha subunit ... poor-responsive inbred mouse strains carry the identical deletion of a branch point in the IL-3 receptor alpha subunit gene. ... poor-responsive inbred mouse strains carry the identical deletion of a branch point in the IL-3 receptor alpha subunit gene. ...
  https://www.jax.org/strain/000646
*  Recombinant Porcine IL-6 Protein, CF 686-PI-025/CF: R&D Systems
IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6 R alpha ... Interleukin 6. Entrez Gene IDs. 3569 (Human); 16193 (Mouse); 24498 (Rat); 399500 (Porcine); 280826 (Bovine); 403985 (Canine); ... and a signal transducing subunit (gp130). IL-6 binds to IL-6 R alpha, triggering IL-6 R alpha association with gp130 and gp130 ... Interleukin-6 (IL-6) is a pleiotropic, alpha -helical, 22-28 kDa phosphorylated and variably glycosylated cytokine that plays ...
  https://www.rndsystems.com/products/recombinant-porcine-il-6-protein-cf_686-pi-cf
*  Interleukin 11 - Wikipedia
... receptor alpha and stoichiometry of in vitro IL-11 receptor complexes with gp130". J. Biol. Chem. 271 (48): 30986-91. doi: ... distinguished based on their use of the common co-receptor gp130. Signal specificity is provided by the IL-11Rα subunit. Signal ... A murine knockout model has been produced for this particular gene, with initial studies involving IL11 role in bone ... 1999). "Definition of receptor binding sites on human interleukin-11 by molecular modeling-guided mutagenesis". Eur. J. Biochem ...
  https://en.wikipedia.org/wiki/Interleukin_11
*  IL6RA, Interleukin-6 Receptor Subunit Alpha | SpringerLink
Interleukin-6 receptor subunit alpha The interleukin-6 receptor (IL-6R) is a type I transmembrane protein that was cloned and ... A common variant of the interleukin 6 receptor (IL-6r) gene increases IL-6r and IL-6 levels, without other inflammatory effects ... CD126; Glycoprotein 80; gp80; IL-6R; IL-6Rα; Interleukin-6 receptor subunit alpha ... Garbers C., Rose-John S. (2018) IL6RA, Interleukin-6 Receptor Subunit Alpha. In: Choi S. (eds) Encyclopedia of Signaling ...
  https://link.springer.com/referenceworkentry/10.1007/978-3-319-67199-4_101661
*  Anti-IL11RA 抗体 [EPR5446] (ab125015) | アブカム
Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal ... IL-11R subunit alpha antibody. *IL-11R-alpha antibody. *IL-11RA antibody ... Entrez Gene: 3590 Human. *Omim: 600939 Human. *SwissProt: Q14626 Human. *Unigene: 591088 Human ... Belongs to the type I cytokine receptor family. Type 3 subfamily.. Contains 2 fibronectin type-III domains.. Contains 1 Ig-like ...
  http://www.abcam.co.jp/il11ra-antibody-epr5446-ab125015.html
*  Janus kinase 2 - Wikipedia
"JAK2 and JAK1 constitutively associate with an interleukin-5 (IL-5) receptor alpha and betac subunit, respectively, and are ... JAK2 gene fusions with the TEL(ETV6) (TEL-JAK2) and PCM1 genes have been found in patients suffering leukemia, particularly ... "Physical interaction between interleukin-12 receptor beta 2 subunit and Jak2 tyrosine kinase: Jak2 associates with cytoplasmic ... the GM-CSF receptor family (IL-3R, IL-5R and GM-CSF-R), the gp130 receptor family (e.g., IL-6R), and the single chain receptors ...
  https://en.wikipedia.org/wiki/Janus_kinase_2