*  Selected Studies on the Toxicity of Thimerosal Published in Peer Reviewed Scientific and Medical Journals
Sperm, inositol trisphosphate, and thimerosal-induced intracellular Ca2+ elevations in rabbit eggs. Fissore RA, Robl JM (1993 ... Cardiac ryanodine receptor activity is altered by oxidizing reagents in either the luminal or cytoplasmic solution. Eager and ... Genes Immun. 2002 Aug;3(5):270-8.. http://www.nature.com/gene/journal/v3/n5/pdf/6363854a.pdf The major source of thimerosal ( ... Modulation of inositol 1,4,5-trisphosphate binding to the various inositol 1,4,5-trisphosphate receptor isoforms by thimerosal ...
  http://www.whale.to/vaccine/thim.html
*  Itpr2 - Inositol 1,4,5-trisphosphate receptor type 2 - Mus musculus (Mouse) - Itpr2 gene & protein
Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release ... Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release ... Inositol 1,4,5-trisphosphate receptor type 2Add BLAST. 2701. Amino acid modifications. Feature key. Position(s). Description ... Inositol 1,4,5-trisphosphate bindingBy similarity. 5. ,p>This subsection of the 'Family and Domains' section describes a region ...
  http://www.uniprot.org/uniprot/Q9Z329
*  Itpr2 - Inositol 1,4,5-trisphosphate receptor type 2 - Mus musculus (Mouse) - Itpr2 gene & protein
Inositol 1,4,5-trisphosphate receptor type 2Imported. ,p>Information which has been imported from another database using ... p>This subsection of the 'Names and taxonomy' section indicates the name(s) of the gene(s) that code for the protein sequence(s ... p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of ... p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source ...
  http://www.uniprot.org/uniprot/B2KF89
*  ITPR1 - Inositol 1,4,5-trisphosphate receptor type 1 - Bos taurus (Bovine) - ITPR1 gene & protein
Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5- ... trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1 ... Inositol 1,4,5-trisphosphate receptor type 1Add BLAST. 2709. Amino acid modifications. Feature key. Position(s). Description ... Inositol 1,4,5-trisphosphate bindingBy similarity. 5. ,p>This subsection of the 'Family and Domains' section describes a region ...
  http://www.uniprot.org/uniprot/Q9TU34
*  KAKEN - Research Projects | Regulatory mechanism of neurotransmitter release (KAKENHI-PROJECT-08044254)
Publications] Nagai,T.: 'The expression of the mouse Zic1,Zic2,and Zic3 gene suggests an essential role for Zic genes in body ... Publications] Zhao,H.: 'Functional expression of a mammalian odorant receptor.' Science.279.237-242 (1998). *. Description. 「研究 ... Presynaptic injection of inositol 1,3,4,5-tetraphosphate, inositol 1,3,4,5,6-pentakisphosphate, or inositol 1,2,3,4,5,6- ... Publications] Nagai, T.et al.: 'The expression of the mouse Zic1, Zic2, and Zic3 gene suggests an essential role for Zic genes ...
  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-08044254/
*  ITPR1 gene - Genetics Home Reference
From NCBI Gene:. This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4 ... ITPR1 gene. inositol 1,4,5-trisphosphate receptor type 1. Enable Javascript to view the expand/collapse boxes.. Open All Close ... this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type ... Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5- ...
  https://ghr.nlm.nih.gov/gene/ITPR1
*  ITPR1 - Wikipedia
"Heteroligomers of type-I and type-III inositol trisphosphate receptors in WB rat liver epithelial cells". The Journal of ... "Entrez Gene: ITPR1 inositol 1,4,5-triphosphate receptor, type 1". Ando H, Mizutani A, Matsu-ura T, Mikoshiba K (Mar 2003). " ... Inositol triphosphate Inositol triphosphate receptor GRCh38: Ensembl release 89: ENSG00000150995 - Ensembl, May 2017 GRCm38: ... receptor-binding protein, is released from the IP3 receptor upon IP3 binding to the receptor". The Journal of Biological ...
  https://en.wikipedia.org/wiki/ITPR1
*  ITPR2 - Wikipédia, a enciclopédia livre
A proteína codificada por este gene é um receptor para o inositol trifosfato e um canal de cálcio.[2] ... Entrez Gene: inositol 1». *↑ Yamamoto-Hino M, Sugiyama T, Hikichi K; et al. (1994). «Cloning and characterization of human type ... Receptor de inositol trifosfato. Referências[editar , editar código-fonte]. *↑ « ... Ontologia do gene. Função molecular. •inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity. •calcium ion ...
  https://pt.wikipedia.org/wiki/ITPR2
*  Gene Ontology Classifications
... receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ ... This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate ( ... Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a RING domain- ... Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc ...
  http://www.informatics.jax.org/go/marker/MGI:1924983
*  anti-BANK1 antibody, Internal | GeneTex
B-cell scaffold protein with ankyrin repeats 1) for FACS, WB. Anti-BANK1 pAb (GTX81106) is tested in Human samples. 100% Ab- ... The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium ... This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1,4,5-trisphosphate receptors. Polymorphisms in ... For short-term storage, store at 4° C (up to 10 days). For long-term storage, aliquot and store at -20ºC or below. Avoid ...
  http://www.genetex.com/BANK1-antibody-Internal-GTX81106.html
*  ITPR2 - Wikipedia
The protein encoded by this gene is both a receptor for inositol triphosphate and a calcium channel. Inositol trisphosphate ... 2008). "Hypoxia differently modulates gene expression of inositol 1,4,5-trisphosphate receptors in mouse kidney and HEK 293 ... 2008). "Selective coupling of type 6 adenylyl cyclase with type 2 IP3 receptors mediates direct sensitization of IP3 receptors ... "Entrez Gene: inositol 1". Yamamoto-Hino M, Sugiyama T, Hikichi K, et al. (1994). "Cloning and characterization of human type 2 ...
  https://en.wikipedia.org/wiki/ITPR2
*  ahcyl1 TaqMan SNP Genotyping Assays
117 ahcyl1 TaqMan 5'-nuclease assay chemistry provides a fast and simple way to get single nucleotide polymorphism (SNP) ... The protein encoded by this gene interacts with inositol 1,4,5-trisphosphate receptor, type 1 and may be involved in the ... Entrez Gene IDs. Gene Symbols. Gene Name. Assay IDs. Entrez Gene IDs. Gene Symbols. RefSeq Accession numbers. GenBank mRNA ... RNAdb IDs and Gene Symbols. Supported Keywords:. Gene Symbol. RefSeq mRNA Accession. Entrez Gene ID. UniGene ID. Gene Alias. ...
  https://www.thermofisher.com/order/genome-database/browse/genotyping/keyword/AHCYL1
*  Oscillatory Ca2+ Signaling in the Isolated Caenorhabditis elegans Intestine | JGP
Inositol trisphosphate mediates a RAS-independent response to LET-23 receptor tyrosine kinase activation in C. elegans. Cell. ... The ability of one gene mutation to alter the phenotype induced by another mutant gene suggests that the two genes interact in ... The inositol trisphosphate receptor regulates a 50-second behavioral rhythm in C. elegans. Cell. 98:757-767. ... Single-channel recordings of recombinant inositol trisphosphate receptors in mammalian nuclear envelope. Biophys. J. 81:117-124 ...
  http://jgp.rupress.org/content/126/4/379
*  Plus it
2008) The tyrosine phosphatase STEP mediates AMPA receptor endocytosis after metabotropic glutamate receptor stimulation. J ... 1999) Calcineurin controls inositol 1,4,5-trisphosphate type 1 receptor expression in neurons. Proc Natl Acad Sci U S A 96:5797 ... The few examples mentioned above might be of interest in the context of AD, but other NFAT target genes previously identified ... 2007) NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders. Nat Rev Neurosci 8:413-426. ...
  http://www.jneurosci.org/content/32/9/3176
*  Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).. ... HCA RNA Cell Line for Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1. ... Generation and annotation of the DNA sequences of human chromosomes 2 and 4.. ...
  https://pharos.nih.gov/idg/targets/Q6GPH6
*  Protocols and Video Articles Authored by Solomon H. Snyder
Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding' ... DANGER1A, which regulates the inositol trisphosphate receptor, promotes the differentiation and outgrowth of neuronal processes ... Gene Transcription by P53 Requires Inositol Polyphosphate Multikinase As a Co-activator Cell Cycle (Georgetown, Tex.). Jun, ... Inositol Polyphosphate Multikinase is a Coactivator for Serum Response Factor-dependent Induction of Immediate Early Genes ...
  https://www.jove.com/author/Solomon+H._Snyder
*  UniProtKB/SwissProt variant VAR 069569
ITPR1 gene p.Val1553Met mutation in Russian family with mild Spinocerebellar ataxia. Shadrina M.I.; Shulskaya M.V.; Klyushnikov ... Inositol 1,4,5-trisphosphate receptor type 1. Gene: ITPR1 Chromosomal location: 3p25-p26 ... ECO:0000269,PubMed:22986007, ECO:0000269,PubMed:26770814}. Note=The disease is caused by mutations affecting the gene ... 1. The score within a Blosum matrix for the corresponding wild-type to variant amino acid change. The log-odds score measures ...
  http://web.expasy.org/variant_pages/VAR_069569.html
*  STIM1 as a key regulator for Ca2+ homeostasis in skeletal-muscle development and function | Springer for Research & Development
Identification of the coupling between skeletal muscle store-operated Ca2+entry and the inositol trisphosphate receptor. Proc ... Gene expression involved in Ca 2+ and/or contractility. Plots represent gene expression in quadriceps skeletal-muscle samples ... Abbreviations: DHPR, dihydropyridine receptor; RyR, ryanodine receptor; SOCE, store-operated Ca2+ entry; STIM, stromal ... Edgar R, Domrachev M, Lash AE: Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic ...
  https://rd.springer.com/article/10.1186/2044-5040-1-16
*  Human Molecular Genetics | Paperity
Identification of plexin A4 as a novel clusterin receptor links two Alzheimer's disease risk genes Aug 2016 , Silvia S. Kang, ... Higher gene expression of the inositol 1,4,5-trisphosphate receptor 2 gene (ITPR2), encoding the IP3 receptor 2 (IP3R2), was ... Genetic ablation of IP3 receptor 2 increases cytokines and decreases survival of SOD1G93A mice Aug 2016 , Kim A. Staats, ... Proteomics to study DNA-bound and chromatin-associated gene regulatory complexes Sep 2016 , Michael Wierer, Matthias Mann ...
  http://paperity.org/journal/116163/human-molecular-genetics
*  Produktübersicht anti-ERLIN2 Antikörper
... signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic ... The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5- ... trisphosphate (IP3) ... swine erlin2 gene has a closer genetic relationship with the ... Novel Mutations in Endoplasmic Reticulum Lipid Raft-associated Protein 2 Gene Cause Pure Hereditary Spastic Paraplegia Type 18 ...
  http://www.antikoerper-online.de/abstract/ER+Lipid+Raft+Associated+2+
*  RETRACTED ARTICLE: Gene expression profiling analysis of the putamen for the investigation of compensatory mechanisms in...
... is affecting 5 million people worldwide, but the response mechanisms of the striatum are still unclear. Therefore, ... Gene expression patterns for GDNF and its receptors in the human putamen affected by Parkinson's disease: a real-time PCR study ... Recent findings have indicated that interaction between Bcl-2 and inositol 1,4,5-trisphosphate (IP3) receptor Ca2+ channels on ... The degree of a gene is the number of its neighborhood genes in PPI network. One gene with high degree, termed a hub gene, ...
  https://rd.springer.com/article/10.1186/1471-2377-13-181
*  OTTHUMP00000209578 | definition of OTTHUMP00000209578 by Medical dictionary
A gene on chromosome 3p26.1 that encodes an intracellular receptor for a so-called second messenger (inositol 1,4,5- ... trisphosphate (IP3)) which, once stimulated by IP3, mediates calcium release from the endoplasmic reticulum. The three IP3 ... receptor subtypes-IP3R1, IP3R2 and IP3R3-are present in the wild as homo- and heterotetramers, are associated with calmodulin ...
  https://medical-dictionary.thefreedictionary.com/OTTHUMP00000209578
*  ITPR3 - Wikipedia
... is a protein which in humans is encoded by the ITPR3 gene. The protein encoded by this gene is both a receptor for inositol ... Inositol trisphosphate receptor GRCh38: Ensembl release 89: ENSG00000096433 - Ensembl, May 2017 GRCm38: Ensembl release 89: ... Ogasawara H (2008). "The calcium kinetics and inositol trisphosphate receptor properties shape the asymmetric timing window of ... Genes Immun. 9 (3): 264-6. doi:10.1038/gene.2008.12. PMID 18340361. Wu Z, Bowen WD (2008). "Role of sigma-1 receptor C-terminal ...
  https://en.wikipedia.org/wiki/ITPR3
*  Syndecan-2 - Wikipedia
... trisphosphate receptor with 4.1N protein in neurons". Mol. Cell. Neurosci. 22 (2): 271-83. doi:10.1016/s1044-7431(02)00027-1. ... Syndecan-2 is a protein that in humans is encoded by the SDC2 gene. The protein encoded by this gene is a transmembrane (type I ... 8 translocation occurring within the GRPR gene and 3' to the SDC2 gene". Hum. Mol. Genet. 6 (8): 1241-50. doi:10.1093/hmg/6.8. ... "Entrez Gene: SDC2 syndecan 2". Maximov A, Tang TS, Bezprozvanny I (February 2003). "Association of the type 1 inositol (1,4,5)- ...
  https://en.wikipedia.org/wiki/Syndecan-2
*  CA8 - Wikipedia
However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene ... Hirota J, Ando H, Hamada K, Mikoshiba K (2003). "Carbonic anhydrase-related protein is a novel binding protein for inositol 1,4 ... Carbonic anhydrase-related protein is an enzyme that in humans is encoded by the CA8 gene. The protein encoded by this gene was ... "Entrez Gene: CA8 carbonic anhydrase VIII". Hirota J, Ando H, Hamada K, Mikoshiba K (Jun 2003). "Carbonic anhydrase-related ...
  https://en.wikipedia.org/wiki/CA8