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*  IJMS | Free Full-Text | Noncanonical Reactions of Flavoenzymes | HTML
In these enzymes, the flavin plays either a direct role in acid/base reactions or as a nucleophile or electrophile. In addition ... In these reactions, the protein environment modulates the reactivity of the flavin to perform novel chemistries. Recent ... the flavin cofactor is proposed to function as a ... environment modulates the chemical reactivity of the flavin to ... Enzymes containing flavin cofactors are predominantly involved in redox reactions in numerous cellular processes where the ...
  http://www.mdpi.com/1422-0067/13/11/14219/htm
*  FMN riboswitch - Wikipedia
Serganov A, Huang L, Patel DJ (2009). "Coenzyme recognition and gene regulation by a flavin mononucleotide riboswitch". Nature ... untranslated regions of prokaryotic mRNAs that encode for flavin mononucleotide (FMN) biosynthesis and transport proteins. This ... Winkler, WC; Cohen-Chalamish S; Breaker RR (2002). "An mRNA structure that controls gene expression by binding FMN". Proc Natl ... Vitreschak AG, Rodionov DA, Mironov AA, Gelfand MS (2002). "Regulation of riboflavin biosynthesis and transport genes in ...
  https://en.wikipedia.org/wiki/FMN_riboswitch
*  FaQR, Required for the Biosynthesis of the Strawberry Flavor Compound 4-Hydroxy-2,5-Dimethyl-3(2H)-Furanone, Encodes an Enone...
... a novel primary auxin-response gene, encodes a flavin mononucleotide-binding quinone reductase. Plant Physiol. 128, 578-590. ... The relative gene expression was determined using an 18S-26S interspacer gene as an endogenous control gene. The increase in ... The gene expression analyses and LCM studies suggest that the strawberry FaQR gene is related to the fruit ripening process and ... FaQR Is a Fruit Ripening-Related Gene. The spatial and temporal expression patterns of the FaQR gene were studied using ...
  http://www.plantcell.org/content/18/4/1023.long
*  Aliivibrio fischeri - Wikipedia
The reduced flavin mononucleotide (FMNH) is provided by the fre gene, also referred to as luxG. In A. fischeri, it is directly ... Luciferase produces blue/green light through the oxidation of reduced flavin mononucleotide and a long-chain aldehyde by ... The bacterial luciferin-luciferase system is encoded by a set of genes labelled the lux operon. In A. fischeri, five such genes ... This operon has a known gene sequence of luxCDAB(F)E, where luxA and luxB code for the protein subunits of the luciferase ...
  https://en.wikipedia.org/wiki/Aliivibrio_fischeri
*  Biostimulation and microbial community profiling reveal insights on RDX transformation in groundwater
... two flavin mononucleotide‐containing oxidoreductase genes xenA and xenB, have been cloned from Pseudomonas (Blehert, Fox, & ... The use of functional gene data along with microbial diversity data is starting to improve our understanding of which genes are ... A total of 98,405 bacterial 16S rRNA gene sequences were recovered for the CdV‐16‐4ip sample and used for community analyses by ... Andeer P., Stahl D. A., Bruce N. C., & Strand S. E. (2009). Lateral transfer of genes for hexahydro‐1,3,5‐trinitro‐1,3,5‐ ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC5387309/
*  Flavin adenine dinucleotide synthetase 1 - Wikipedia
This gene encodes the enzyme that catalyzes adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD ... Flavin adenine dinucleotide synthetase 1 is a protein that in humans is encoded by the FLAD1 gene. ... "Entrez Gene: Flavin adenine dinucleotide synthetase 1". Retrieved 2016-03-04. This article incorporates text from the United ...
  https://en.wikipedia.org/wiki/Flavin_adenine_dinucleotide_synthetase_1
*  anti-FLAD1 antibody, C-term | GeneTex
FAD1 flavin adenine dinucleotide synthetase homolog (S. cerevisiae)) for WB. Anti-FLAD1 pAb (GTX80500) is tested in Human ... This gene encodes the enzyme that catalyzes adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD ... FAD1 flavin adenine dinucleotide synthetase homolog (S. cerevisiae). Background. ... FAD synthetase region, PP591, FLAD1, Molybdenum cofactor biosynthesis protein-like region, FLAD1, FAD pyrophosphorylase, Flavin ...
  http://www.genetex.com/FLAD1-antibody-C-term-GTX80500.html
*  OriGene - NDOR1 (NM 014434) Human ORF cDNA Clone
Gene Summary: This gene encodes an NADPH-dependent diflavin reductase that contains both flavin mononucleotide (FMN) and flavin ... SgfI-MluI Cloning Scheme for this gene Plasmid Map OTI Annotation:. This clone was engineered to express the complete ORF with ... Expression varies depending on the nature of the gene.. OTI Disclaimer:. The molecular sequence of this clone aligns with the ... This database is built by NCBI, and, provides only a single record for each gene/transcript. More details.. Due to SNPs, each ...
  http://www.origene.com/Human_ORF/RC204845.aspx
*  Nitrilotriacetate monooxygenase - Wikipedia
... and analysis of a gene cluster from Chelatobacter heintzii ATCC 29600 encoding nitrilotriacetate monooxygenase and NADH:flavin ... mononucleotide oxidoreductase". J. Bacteriol. 179 (4): 1112-1116. PMC 178806 . PMID 9023192. Nitrilotriacetate monooxygenase at ... Knobel, H.R.; Egli, T.; van der Meer, J.R. (1996). "Cloning and characterization of the genes encoding nitrilotriacetate ...
  https://en.wikipedia.org/wiki/Nitrilotriacetate_monooxygenase
*  RFK - Riboflavin kinase - Homo sapiens (Human) - RFK gene & protein
... to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reactive ... Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the ... Gene expression databases. Bgee dataBase for Gene Expression Evolution. More...Bgeei. ENSG00000135002 Expressed in 242 organ(s ... based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.,p>,a href='/help/gene_centric_isoform_ ...
  https://www.uniprot.org/uniprot/Q969G6
*  RNA-seq analysis of the Rhizobium tropici CIAT 899 transcriptome shows similarities in the activation patterns of symbiotic...
... under salt stress nodM and a gene that codes for a flavine mononucleotide reductase (RTCIAT899_PB02705) were significantly up- ... tadBCD and cpaABCDEF genes) [30], or ABC-type transport (several genes: e.g. phn genes). In addition, a set of genes located in ... Identification of the differentially expressed genes. To identify differentially expressed genes in the presence of nod gene ... Ct method and normalized to the reference gene RNA 16S for 20 differentially expressed genes. HP: gene that codes for a ...
  https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-016-2543-3
*  Crystal structure of a c‐di‐AMP riboswitch reveals an internally pseudo‐dimeric RNA | The EMBO Journal
Serganov A, Huang L, Patel DJ (2009) Coenzyme recognition and gene regulation by a flavin mononucleotide riboswitch. Nature 458 ... Block KF, Hammond MC, Breaker RR (2010) Evidence for widespread gene control function by the ydaO riboswitch candidate. J ... Deigan KE, Ferré‐D'Amaré AR (2011) Riboswitches: discovery of drugs that target bacterial gene‐regulatory RNAs. Acc Chem Res 44 ... To elucidate the molecular basis for specific binding of c‐di‐AMP by a gene‐regulatory mRNA domain, we have determined the co‐ ...
  http://emboj.embopress.org/content/33/22/2692
*  A modular yeast biosensor for low-cost point-of-care pathogen detection | Science Advances
FMN, flavin mononucleotide; FAD, flavin adenine dinucleotide; FPP, farnesyl pyrophosphate; GGPP, geranylgeranyl pyrophosphate ... Cloning and characterization of FAD1, the structural gene for flavin adenine dinucleotide synthetase of Saccharomyces ... Scarless gene deletions and gene replacements were carried out using delitto perfetto (33). Endogenous yeast promoters, ... JCat: A novel tool to adapt codon usage of a target gene to its potential expression host. Nucleic Acids Res. 33, W526-W531 ( ...
  http://advances.sciencemag.org/content/3/6/e1603221
*  Microbial responses to xenobiotic compounds. Identification of genes that allow Pseudomonas putida KT2440 to cope with 2,4,6...
Riefler, R.G., and Smets, B.F. (2002) NAD(P)H:flavin mononucleotide oxidoreductase inactivation during 2,4,6-trinitrotoluene ... Zenno, S., Saigo, K., Kanoh, H., and Inouye, S. (1994) Identification of the gene encoding the major NAD(P)H-flavin ... to a flavin reductase similar in biochemical properties to FRase I, the major flavin reductase in Vibrio fischeri, by a single ... Miura, K., Tomioka, Y., Suzuki, H., Yonezawa, M., Hishinuma, T., and Mizugaki, M. (1997) Molecular cloning of the nemA gene ...
  http://onlinelibrary.wiley.com/doi/10.1111/j.1751-7915.2009.00085.x/references
*  Frontiers | Novel, Deep-Branching Heterotrophic Bacterial Populations Recovered from Thermal Spring Metagenomes | Microbiology
A survey of similar phylotypes (> 97% nt identity) within 16S rRNA gene datasets suggest that the newly described organisms are ... A survey of similar phylotypes (, 97% nt identity) within 16S rRNA gene datasets suggest that the newly described organisms are ... Analysis of conserved phylogenetic marker genes indicated that two of the phylotypes represent separate groups of an ... Analysis of conserved phylogenetic marker genes indicated that two of the phylotypes represent separate groups of an ...
  https://www.frontiersin.org/articles/10.3389/fmicb.2016.00304/full
*  Students and Research Projects - CLIB-Graduate Cluster Industrial Biotechnology
Flavin mononucleotide-based fluorescent protein as a reporter of hypoxic gene expression in fungi.. expression 2009-10-01. ... Methods for fungal gene cluster analysis. polyomics 2010-12-01. Daniel. Dörr (more). Dr. Jörn Kalinowski, Prof. Dr. Jens Stoye ... A novel system for the functional expression of clustered genes. expression 2009-05-01. Anita. Loeschcke (more). Prof. Dr. Karl ... Genome-wide exact gene expression quantification from RNAseq data in complex eukaryotic genomes. --. polyomics 2013-04-01. Kai ...
  http://www.clib-graduatecluster.de/?-Students-and-Research-Projects-
*  Human Metabolome Database: Showing metabocard for Riboflavin (HMDB0000244)
Gene Name:. ACP2. Uniprot ID:. P11117 Molecular weight:. 48343.92. Reactions. Flavin Mononucleotide + Water → Riboflavin + ... Gene Name:. ACP1. Uniprot ID:. P24666 Molecular weight:. 18042.315. Reactions. Flavin Mononucleotide + Water → Riboflavin + ... Gene Name:. ACP5. Uniprot ID:. P13686 Molecular weight:. 36598.47. Reactions. Flavin Mononucleotide + Water → Riboflavin + ... Gene Name:. ACPP. Uniprot ID:. P15309 Molecular weight:. 44565.715. Reactions. Flavin Mononucleotide + Water → Riboflavin + ...
  http://www.hmdb.ca/metabolites/HMDB0000244
*  ASMscience | Biodegradation of Synthe
... flavin mononucleotide oxidoreductase. J. Bacteriol. 179:1112-1116.. ... Overview of the gene cluster encoding NTA monooxygenase of C. heintzii. The genes nmoA, nmoB. nmoR. and nmoT and their ... Overview of the gene cluster encoding NTA monooxygenase of C. heintzii. The genes nmoA, nmoB. nmoR. and nmoT and their ... The nature and functioning of cytochromes P450 and flavin-containing-monooxygenases, p. 70-121. In B. Testa, and J. Caldwell ( ...
  http://www.asmscience.org/content/book/10.1128/9781555818098.chap15
*  LuxG Is a Functioning Flavin Reductase for Bacterial Luminescence | Journal of Bacteriology
luxG has been proposed to be a flavin reductase that supplies reduced flavin mononucleotide (FMN) for bacterial luminescence. ... the flavin reductase found in E. coli (2, 15). Therefore, it has been postulated that the luxG gene product is a flavin ... Identification of the genes encoding NAD(P)H-flavin oxidoreductases that are similar in sequence to Escherichia coli Fre in ... Characterization of the flavin reductase gene (fre) of Escherichia coli and construction of a plasmid for overproduction of the ...
  https://jb.asm.org/content/190/5/1531.full?maxtoshow=&hits=10&RESULTFORMAT=&fulltext=asterisk&searchid=1&FIRSTINDEX=730&resourcetype=HWFIG
*  Development of stable reporter system cloning luxCDABE genes into chromosome of Salmonella enterica serotypes using Tn7...
Genes luxCDABE encode bacterial luciferase which catalyzes the oxidation of reduced flavin mononucleotide (FMNH2) and a long ... The expression of lux genes is driven by E. coli frr gene promoter between the XhoI sites. ... The promoter of the housekeeping gene frr [27] was amplified from the E. coli K-12 MG1655 genome using PG209 ( ... Insertion of lux genes into the chromosome of Salmonella enterica Bioluminescence was established in the chromosome of the ...
  http://www.biomedsearch.com/nih/Development-stable-reporter-system-cloning/20653968.html
*  Bioluminescent bacteria - Wikipedia
... reduced flavin mononucleotide) and a long-chain aldehyde to produce FMN (flavin mononucleotide), water and a corresponding ... Nevertheless, all bio-luminescent bacteria share a common gene sequence: the enzymatic oxidation of Aldehyde and reduced Flavin ... The products of this oxidation reaction include an oxidized flavin mononucleotide, a fatty acid chain, and energy in the form ... Despite this common gene organization, variations, such as the presence of other lux genes, can be observed among species. ...
  https://en.wikipedia.org/wiki/Bioluminescent_bacteria
*  Riboflavin Depletion Promotes Tumorigenesis in HEK293T and NIH3T3 Cells by Sustaining Cell Proliferation and Regulating Cell...
Promotes Tumorigenesis in HEK293T and NIH3T3 Cells by Sustaining Cell Proliferation and Regulating Cell Cycle-Related Gene ... Because flavin mononucleotide and flavin adenine dinucleotide act as electron carriers for a range of redox reactions, ... Mechanistically, gene expression profiling and gene ontology analysis were used to identify abnormally expressed genes induced ... Mechanistically, gene expression profiling and gene ontology analysis were used to identify abnormally expressed genes induced ...
  https://www.deepdyve.com/lp/ou_press/riboflavin-depletion-promotes-tumorigenesis-in-hek293t-and-nih3t3-jxCrv0HI20
*  Inverted repeat - Wikipedia
A simplified example of the flavin mononucleotide (FMN) riboswitch is shown in the illustration. This riboswitch exists in the ... The antithrombin III gene's coding region is an example of an imperfect inverted repeat as shown in the figure on the right. ... These repeated DNA sequences often range from a pair of nucleotides to a whole gene, while the proximity of the repeat ... Specifically, the missense mutation would lead to a defective gene and a deficiency in antithrombin which could result in the ...
  https://en.wikipedia.org/wiki/Inverted_repeat
*  Riboflavin-Doped DNA Thin Films | Open Science
... reduction and oxidation processes and is metabolized in vivo to flavin adenine dinucleotide followed by flavin mononucleotide. ... As photosensitizing agent, RF is also used to improve blood clotting via platelet treatment and to detect gene mutations caused ... 1982 The photophysical and photochemical properties of flavins (isoalloxazines). Chem. Soc. Rev. 11, 15-39. (doi:10.1039/ ... 2012 Hydrogen-bonding modulation of excited-state properties of flavins in a model of aqueous confined environment. Photochem. ...
  http://rsos.royalsocietypublishing.org/content/5/2/171179
*  Responses of hyperthermophilic crenarchaea to UV irradiation | Genome Biology | Full Text
Differential effects on the expression of the three transcription factor B (tfb) genes hint at a mechanism for the modulation ... No increase in expression of DNA repair genes following UV irradiation was observed. There was, however, a clear ... DNA damage leads to cellular responses that include the increased expression of DNA repair genes, repression of DNA replication ... Riboflavin is a precursor of FAD and flavin mononucleotide (FMN) [16]. Given the observation that many FAD-dependent ...
  https://genomebiology.biomedcentral.com/articles/10.1186/gb-2007-8-10-r220