Loading...
*  Association between active genes occurs at nuclear speckles and is modulated by chromatin environment. - Radcliffe Department...
Those genes most frequently in association lie in decondensed stretches of chromatin. By replacing the mouse alpha-globin gene ... hence the apparent nonrandom association between genes). Thus, association between active genes may result from their location ... Using human erythropoiesis as a model, we show that five cotranscribed genes, which are found on four different chromosomes, ... We see no evidence that cotranscribed erythroid genes associate at shared transcription foci, but we do see stochastic ...
  https://www.rdm.ox.ac.uk/publications/34396
*  Slc4a1 MGI Mouse Gene Detail - MGI:109393 - solute carrier family 4 (anion exchanger), member 1
J:35614 Kopito RR, et al., Primary structure and transmembrane orientation of the murine anion exchange protein. Nature. 1985 ... Homozygotes for null mutations exhibit retarded growth, severe spherocytosis, hemolytic anemia, lack of erythrocyte glycophorin ... protein coding gene. Chr11:102348820-102366203 (-). 129S1/SvImJ MGP_129S1SvImJ_G0019232. protein coding gene. Chr11:105314974- ... protein coding gene. Chr11:100876913-100894310 (-). AKR/J MGP_AKRJ_G0019169. protein coding gene. Chr11:103990994-104009893 (-) ...
  http://www.informatics.jax.org/marker/MGI:109393
*  Anion Transport Systems: Continuous Monitoring of Transport by Fluorescence (CMTF) in Cells and Vesicles | Springer for...
Anion transport mechanisms are found in mammalian cell membranes in the form of exchangers or antiporters (Passow, 1987; ... Kopito, R. R., and Lodish, H. F., 1985: Structure of the murine anion exchange protein,J. Cell. Bioch., 29:1-17.CrossRefGoogle ... Frohlich, O., and Gunn, R. B., 1986: Erythrocyte anion transport: the kinetics of a single site obligatory exchange system, ... Kopito, R. R., Andersson, M., and Lodish, H. V., 1987: Structure and organization of the murine band 3 gene. J. Biol. Chem., ...
  https://rd.springer.com/chapter/10.1007/978-1-4757-9601-8_18
*  SLC4A2 - Wikipedia
Anion exchange protein 2 (AE2) is a membrane transport protein that in humans is encoded by the SLC4A2 gene. AE2 is ... "Entrez Gene: SLC4A2 solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)". Gawenis ... Havenga MJ, Bosman GJ, Appelhans H, De Grip WJ (1995). "Expression of the anion exchanger (AE) gene family in human brain. ... Gehrig H, Müller W, Appelhans H (1992). "Complete nucleotide sequence of band 3 related anion transport protein AE2 from human ...
  https://en.wikipedia.org/wiki/SLC4A2
*  Band 3 Missense Mutations and Stomatocytosis: Insight into the Molecular Mechanism Responsible for Monovalent Cation Leak
Q. Zhu and J. R. Casey, "The substrate anion selectivity filter in the human erythrocyte Cl. −. /. HCO. 3. −. exchange protein ... P. Jarolim, J. Palek, D. Amato et al., "Deletion in erythrocyte band 3 gene in malaria-resistant Southeast Asian ovalocytosis ... However, the anion permeability of these cells is decreased suggesting a loss of anion exchange function of the protein [20]. ... a A mutated state where no anion exchange occurs only cation leak exists and a B mutated state where anion exchange and cation ...
  https://www.hindawi.com/journals/ijcb/2011/136802/
*  SLC26A3 - Wikipedia
It is different from the anion exchanger that present in erythrocytes, renal tubule, and several other tissues. The protein ... is a protein that in humans is encoded by the SLC26A3 gene. The downregulated-in-adenoma (DRA) is a membrane protein in ... It mediates chloride and bicarbonate exchange and additionally transports sulfate and other anions at the apical membrane, part ... "Mapping of five new putative anion transporter genes in human and characterization of SLC26A6, a candidate gene for pancreatic ...
  https://en.wikipedia.org/wiki/SLC26A3
*  Processing of N-linked oligosaccharide depends on its location in the anion exchanger, AE1, membrane glycoprotein. - Semantic...
30% of the protein was expressed at the cell surface. Moving the N-glycosylation site to the preceding extracellular loop in an ... in the fourth extracellular loop of this polytopic membrane protein, while other isoforms (AE2, AE3 and trout AE1) are N- ... The human erythrocyte anion exchanger (AE)1 (Band 3) contains a single complex N-linked oligosaccharide that is attached to Asn ... Transport activity of AE3 chloride/bicarbonate anion-exchange proteins and their regulation by intracellular pH.. *Deborah ...
  https://www.semanticscholar.org/paper/Processing-of-N-linked-oligosaccharide-depends-on-Li-Quilty/de5776fdb43ad7daff784906004eab86c3727344
*  Lenti-AE1 CAR (scFv-CD28-41BB-CD3ζ, MOv19) Viral Particle vector - Creative Biolabs
The protein encoded by this gene is part of the anion exchanger (AE) family and is expressed in the erythrocyte plasma membrane ... contains 12-14 membrane spanning segments and carries out the stilbene disulphonate-sensitive exchange transport of anions. The ... This protein is predominantly dimeric but forms tetramers in the presence of ankyrin. Many mutations in this gene are known in ... The encoded protein associates with the red cell membrane protein glycophorin A and this association promotes the correct ...
  https://www.creative-biolabs.com/car-t/lenti-ae1-car-scfv-28bb%CE%B6-mov19-vp-3174.htm
*  Cotransporter - Wikipedia
... anion transport protein. This cotransporter is an important integral protein in mammalian erythrocytes and moves chloride ion ... The SLC6A1 gene encodes GABA transporters. The transporters are electrogenic and couples 2 Na+, 1 Cl− and 1 GABA for inward ... The sodium-calcium exchanger exchanges 3 sodium ions for 1 calcium ion and represents a cation antiporter. Cells also contain ... The NKCC1 cotransport protein is found throughout the body but NKCC2 is found only in the kidney and removes the sodium, ...
  https://en.wikipedia.org/wiki/Cotransporter
*  Neuronal anion exchange proteins in Alzheimer's disease pathology | Springer for Research & Development
... proteins are present in human neurons in the brain. Immunohistochemical data indicate that their apparent expression level ... Anion Exchange Neurobiol Aging Alzheimer Hippocampus Large Pyramidal Neuron Aging Erythrocyte This is a preview of subscription ... Alper SL (1991) The band 3-related anion exchanger (AE) gene family. Annu Rev Physiol 53: 549-564PubMedCrossRefGoogle Scholar ... Wood PG (1992) The anion exchange proteins: homology and secondary structure. Prog Cell Res 2: 325-352CrossRefGoogle Scholar ...
  https://rd.springer.com/chapter/10.1007/978-3-7091-7508-8_24
*  Detecting Chloride, Phosphate, Nitrite and Other Anions-Section 21.2 | Thermo Fisher Scientific - JP
... together with an assortment of analytical reagents and methods for direct or indirect quantitation of other inorganic anions, ... erythrocyte Cl-/HCO3- exchangers and the mitochondrial uncoupling protein.. Although SPQ requires UV excitation (as do MQAE and ... is currently in widespread use for detecting CFTR activity using the Cl-/NO3- exchange technique described above.. SPQ has also ... Following cellular entry, the baculovirus moves to the nucleus where Premo Halide Sensor gene is expressed. Premo Halide Sensor ...
  https://www.thermofisher.com/jp/en/home/references/molecular-probes-the-handbook/indicators-for-na-k-cl-and-miscellaneous-ions/detecting-chloride-phosphate-nitrite-and-other-anions.html
*  Protocols and Video Articles Authored by Jongyoon Han
Gene Disruption of Dematin Causes Precipitous Loss of Erythrocyte Membrane Stability and Severe Hemolytic Anemia Blood. 07, ... or anions) with the unipolar ion exchange membrane stack. Combining theoretical analysis, experiment, and numerical modeling, ... Using this principle, we interrogate biomolecular interactions, including protein-DNA binding, protein-protein interaction and ... IEF of proteins was also achieved in a microchannel, and several proteins were focussed within tens of seconds in mm-length ...
  https://www.jove.com/author/Jongyoon_Han
*  Protocols and Video Articles Authored by Max Gassmann
The Ppp1r7 gene encoding Sds22, a regulatory subunit of protein phosphatase 1, shares the promoter region with the Paskin gene ... Cupric ions enter trout erythrocytes as negatively charged complexes with chloride and hydroxyl anions via the band 3-mediated ... Moreover, cuprous ions stimulate Na+H+ exchange and residual Na+ transport causing net Na+ accumulation in the cells. The ... However, PARP1 formed a complex with HIF-1alpha through direct protein interaction and coactivated HIF-1alpha-dependent gene ...
  https://www.jove.com/author/Max_Gassmann
*  EBV-Specific CD8+ T Cell Memory: Relationships Between Epitope Specificity, Cell Phenotype, and Immediate Effector Function |...
... followed by further purification on a Mono Q anion exchange FPLC column (Amersham Pharmacia Biotech). The purified monomers ... YVLDHLIVV derived from the lytic cycle protein BMRF1 (24), and CLGGLLTMV derived from the latent cycle protein LMP2 (25). The ... to remove contaminating erythrocytes. The Ab-coated cells were depleted by multiple rounds of incubation with sheep anti-mouse ... were tetramerized by addition of streptavidin R-phycoerythrin (Molecular Probes, Eugene, OR) at a molar ratio of 4:1, ...
  http://www.jimmunol.org/content/167/4/2019
*  Band 3 - Wikipedia
Band 3 anion transport protein is a phylogenetically-preserved transport protein responsible for mediating the exchange of ... "Deletion in erythrocyte band 3 gene in malaria-resistant Southeast Asian ovalocytosis". Proc. Natl. Acad. Sci. U.S.A. 88 (24): ... The erythrocyte and kidney forms are different isoforms of the same protein. The erythrocyte isoform of AE1, known as eAE1, is ... Band 3 anion transport protein, also known as anion exchanger 1 (AE1) or band 3 or solute carrier family 4 member 1 (SLC4A1), ...
  https://en.wikipedia.org/wiki/Band_3
*  Do my homework for me online - 22+ Banking Resume Templates | Free & Premium Templates | Providence College
... erythrocytes and leukocytes, respectively, using size-exclusion and anion-exchange chromatography (4, 7). The heme has been ... It was found that an addition of betaine, bovine serum albumin, the single-stranded DNA binding protein of the T4 32 gene (gp ... 22+ Banking Templates & Premium? Garlands Exchange (Jai Mala ) : The bride groom exchange garlands of fresh flowers acknowledge ... Relief of amplification inhibition in PCR with bovine serum albumin or T4 gene 32 protein. ...
  http://resourcesed.info/article/74/essay/24/
*  Monocarboxylate transporter 1 - Wikipedia
Zhang GZ, Huang GJ, Li WL, Wu GM, Qian GS (Jul 2002). "[Effect of co-inhibition of MCT1 gene and NHE1 gene on proliferation and ... The protein then undergoes a conformational change to a new 'closed'' conformation that exposes both the proton and lactate to ... For this reason, exchange of one monocarboxylate inside the cell with another outside is considerably faster than net transport ... MCT1 has a substrate binding site open to the extracellular matrix which binds a proton first followed by the lactate anion. ...
  https://en.wikipedia.org/wiki/Monocarboxylate_transporter_1
*  Hydroxycarbamide - Wikipedia
Hydroxyurea has also been prepared by converting a quaternary ammonium anion exchange resin from the chloride form to the ... Hydroxyurea lay dormant for more than fifty years until it was studied as part of an investigation into the toxicity of protein ... Antisickling Agents - Agents used to prevent or reverse the pathological events leading to sickling of erythrocytes in sickle ... and the activation of gamma globin gene expression and subsequent gamma chain synthesis necessary for fetal hemoglobin (HbF) ...
  https://en.wikipedia.org/wiki/Hydroxycarbamide
*  Cryohydrocytosis: increased activity of cation carriers in red cells from a patient with a band 3 mutation | Haematologica
Recently the disease has been linked to mutations in the band 3 protein, the anion-exchange protein (AE1).1,9,10 RBC from such ... 1989) Localization of the ankyrin-binding site on erythrocyte membrane protein, band 3. J Biol Chem 264(27):15893-9. ... 2004) Hereditary haemolytic anaemias: unexpected sequelae of mutations in the genes for erythroid membrane skeletal proteins. J ... Apart from being an anion transport protein, band 3 is also a scaffold for numerous other proteins of the cytoskeleton, ...
  http://www.haematologica.org/content/95/2/189
*  SLC4A3 - Wikipedia
Anion exchange protein 3 is a membrane transport protein that in humans is encoded by the SLC4A3 gene. AE3 is functionally ... 1990). "Regulation of intracellular pH by a neuronal homolog of the erythrocyte anion exchanger". Cell. 59 (5): 927-37. doi: ... "Entrez Gene: SLC4A3 solute carrier family 4, anion exchanger, member 3". Casey JR, Sly WS, Shah GN, Alvarez BV (November 2009 ... exchange protein but it is expressed primarily in brain neurons and in the heart. Like AE2 its activity is sensitive to pH. AE3 ...
  https://en.wikipedia.org/wiki/SLC4A3
*  Jongyun Heo - Department of Chemistry and Biochemistry - College of Science - The University of Texas at Arlington
"The control of S-thiolation by cysteine via gamma-glutamyltranspeptidase and thiol exchanges in erythrocytes and plasma of ... "Superoxide Anion Radical Modulates the Activity of Ras and Ras-Related GTPases by a Radical-Based Mechanism Similar to that of ... "Hydroxylamine Reductase Activity of the Hybrid Cluster Protein from Escherichia coli" Marcus T. Wolfe, Jongyun Heo, John S. ... and Gene Expression, Santiago Lamas and Enrique Cadenas, Eds., Taylor & Francis Group, LLC., New York (2005). ...
  http://www.uta.edu/chemistry/faculty/directory/Heo.php?pane=b
*  The hereditary stomatocytoses | Haematologica
It was discovered that mutations in SLC4A1, which encodes the erythrocyte anion exchanger protein 1 (AE1, band 3), are ... No mutations have been found in the stomatin gene in OHSt patients and production of the protein is normal,12 suggesting that ... The transmembrane domain of band 3 is responsible for its anion exchange activity, transporting bicarbonate ions (produced from ... 2003) The "stomatin" gene and protein in overhydrated hereditary stomatocytosis. Blood 102:2268-77. ...
  http://www.haematologica.org/content/94/8/1039
*  Ankyrin-Tiam1 Interaction Promotes Rac1 Signaling and Metastatic Breast Tumor Cell Invasion and Migration | JCB
... two other members of the anion exchange gene family (Bennet, 1992), Na+/K+-ATPase (Nelson and Veshnock 1987; Zhang et al. 1998 ... purified from human erythrocytes; 5,000 cpm/ng protein) or 125I-labeled recombinant ARD fragment at 4°C for 4 h. Specifically, ... has been detected in a number of functionally distinct proteins participating in protein-protein binding and protein-DNA ... 1991) Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product. Nature. 354:311-314, pmid: ...
  http://jcb.rupress.org/content/150/1/177
*  Southeast Asian ovalocytosis - Wikipedia
"Occurrence of the erythrocyte band 3 (AE1) gene deletion in relation to malaria endemicity in Papua New Guinea". Transactions ... increased tyrosine phosphorylation of the band 3 protein, reduced sulfate anion transport through the cell membrane, and more ... general rigidity of the cell membrane Loss of sensitivity to substances that cause spiculation of cells Reduced anion exchange ... Rather, the defect lies in a protein known as the band 3 protein, which lies in the cell membrane itself. The band 3 protein ...
  https://en.wikipedia.org/wiki/Southeast_Asian_ovalocytosis
*  Induction of Potent CD8 T Cell Cytotoxicity by Specific Targeting of Antigen to Cross-Presenting Dendritic Cells In Vivo via...
XCL1/2-OVA protein was purified by heparin Sepharose affinity chromatography, followed by anion exchange chromatography on a ... B6.XCR1-lacZ mice (The Jackson Laboratory) is a strain in which the XCR1 gene has been replaced by the β-Gal reporter gene; ... Murine splenocytes were obtained by mashing spleens through 70-μm cell sieves into PBS, followed by erythrocyte lysis with ACK ... the identity of the protein was verified by mass spectrometry. XCL1-StrepTag protein was purified from the supernatant using ...
  http://www.jimmunol.org/content/194/3/1069