*  WikiGenes - TUBB3 - tubulin, beta 3 class III
RESULTS: Integrin PCR products corresponding to the beta1-, beta4-, beta5-, and beta8-integrin subunits and the alpha-integrin ... Integrin alpha6beta4 as a suppressor and a predictive marker for peritoneal dissemination in human gastric cancer. Ishii, Y., ... Gene correction of integrin beta4-dependent pyloric atresia-junctional epidermolysis bullosa keratinocytes establishes a role ... Expression of alpha-3, alpha-5, and beta-4 neuronal acetylcholine receptor subunit transcripts in normal and myasthenia gravis ...
  https://www.wikigenes.org/e/gene/e/10381.html
*  ITGB4 - Wikipedia
This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 ... "The coupling of alpha6beta4 integrin to Ras-MAP kinase pathways mediated by Shc controls keratinocyte proliferation". The EMBO ... is a human gene. Integrins are heterodimers composed of alpha and beta subunits, that are noncovalently associated ... Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. ...
  https://en.wikipedia.org/wiki/ITGB4
*  Interactive Fly, Drosophila
Other integrin-ligand interactions. Nine integrin alpha subunits contain an additional domain (termed A or I) that is inserted ... The integrin alpha6 beta4 is a major component of hemidesmosomes; as a part of this structure, integrin alpha6 beta4 mediates ... These results suggest a new type of gene regulation by integrins and by mechanical stress that may involve translation of mRNAs ... Not all integrins possess an alpha subunit I domain, but they all contain a region in their beta subunits that is proposed to ...
  http://www.sdbonline.org/sites/fly/gene/myosph2e.htm
*  Cell Adhesion Molecules in Carcinoma Invasion and Metastasis | SpringerLink
Carter WG, Ryan MC, Gahr PJ (1991) Epiligrin, a new cell adhesion ligand for integrin alpha 3 beta 1 in epithelial basement ... Goldfinger LE, Hopkinson SB, deHart GW, Collawn S, Couchman JR, Jones JC (1999) The alpha3 laminin subunit, alpha6beta4 and ... Fournier AK, Campbell LE, Castagnino P, Liu WF, Chung BM, Weaver VM, Chen CS, Assoian RK (2008) Rac-dependent cyclin D1 gene ... Kawano K, Kantak S, Murai M, Yao C-C, Kramer R (2001) Integrin alpha 3 beta 1 engagement disrupts intercellular adhesion. Exp ...
  https://link.springer.com/chapter/10.1007/978-1-4419-7203-3_1
*  Dystonin - Wikipedia
... plectin and the integrin alpha6beta4 important for hemidesmosome assembly". J. Cell Sci. England. 116 (Pt 2): 387-99. doi: ... "The hemidesmosomal protein bullous pemphigoid antigen 1 and the integrin beta 4 subunit bind to ERBIN. Molecular cloning of ... is a protein that in humans is encoded by the DST gene. This gene encodes a member of the plakin protein family of adhesion ... Dystonin has been shown to interact with Collagen, type XVII, alpha 1, DCTN1 and Erbin. Bullous pemphigoid GRCh38: Ensembl ...
  https://en.wikipedia.org/wiki/Dystonin
*  Collagen, type XVII, alpha 1 - Wikipedia
1998). "Hemidesmosome formation is initiated by the beta4 integrin subunit, requires complex formation of beta4 and HD1/plectin ... This gene encodes the alpha chain of type XVII collagen. Collagen XVII is a transmembrane protein, like collagen XIII, XXIII ... plectin and the integrin alpha6beta4 important for hemidesmosome assembly". J. Cell Sci. England. 116 (Pt 2): 387-99. doi: ... Collagen, type XVII, alpha 1 has been shown to interact with Keratin 18, Actinin alpha 4, Dystonin, Actinin, alpha 1, CTNND1 ...
  https://en.wikipedia.org/wiki/Collagen,_type_XVII,_alpha_1
*  HRAS HRas proto-oncogene, GTPase [Homo sapiens (human)] - Gene - NCBI
... organism-specific biosystemThe integrin alpha6beta4 was discovered in the late 1980s by two different groups and was called ... TNF alpha Signaling Pathway, organism-specific biosystem (from WikiPathways) TNF alpha Signaling Pathway, organism-specific ... complex is composed of a ligand-binding subunit, the ? and ? chains, and a signaling subunit, namely the CD3?, ? and ? chains ... Gene neighbors Overlapping genes and two nearest non-overlapping genes on either side ...
  https://www.ncbi.nlm.nih.gov/gene?LinkName=pubmed_gene_rif&from_uid=22499344
*  Myoepithelial cells: good fences make good neighbors | Breast Cancer Research | Full Text
Muschler J, Lochter A, Roskelley CD, Yurchenco P, Bissell MJ: Division of labor among the alpha6beta4 integrin, beta1 integrins ... Kadoya Y, Kadoya K, Durbeej M, Holmvall K, Sorokin L, Ekblom P: Antibodies against domain E3 of laminin-1 and integrin alpha 6 ... In another study, Allinen and coworkers [70] used SAGE (serial analysis of gene expression) to identify gene expression ... subunit perturb branching epithelial morphogenesis of submandibular gland, but by different modes. J Cell Biol. 1995, 129: 521- ...
  https://breast-cancer-research.biomedcentral.com/articles/10.1186/bcr1286
*  NFKB1 - Wikipedia
Nuclear factor NF-kappa-B p105 subunit is a protein that in humans is encoded by the NFKB1 gene. This gene encodes a 105 kD ... Mercurio AM (2003). "Invasive skin carcinoma--Ras and alpha6beta4 integrin lead the way". Cancer Cell. 3 (3): 201-2. doi: ... the level of its mRNA is strongly regulated by phorbol ester or tumor necrosis factor alpha". Proc Natl Acad Sci U S A. 88 (3 ... "Entrez Gene: NF-κB nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)". "Eye morphology data for Nfkb1 ...
  https://en.wikipedia.org/wiki/NFKB1
*  ITGB4 gene - Genetics Home Reference
The ITGB4 gene provides instructions for making one part (the β4 subunit) of a protein known as an integrin. Integrins are a ... A novel mechanism for integrin-mediated ras activation in breast carcinoma cells: the alpha6beta4 integrin regulates ErbB2 ... Alpha 6 beta 4 integrin abnormalities in junctional epidermolysis bullosa with pyloric atresia. Br J Dermatol. 2001 Feb;144(2): ... ITGB4 gene. integrin subunit beta 4. Enable Javascript to view the expand/collapse boxes.. Printable PDF Open All Close All ...
  https://ghr.nlm.nih.gov/gene/ITGB4
*  Product Overview anti-Integrin beta 4 Antibodies
Selected quality suppliers for anti-Integrin beta 4 antibodies. ... Order monoclonal and polyclonal Integrin beta 4 antibodies for ... This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 ... This work investigates alpha6beta4 integrin genetic variations (A380T and R1281W) and breast cancer risk in an Argentinian ... anti-Integrin, alpha 7 (ITGA7) Antibodies * anti-Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha ...
  http://www.antibodies-online.com/integrin-complex-pathway-122/integrin-beta-4-antibody-42/
*  Produktübersicht anti-Integrin beta 4 Antikörper
Ausgesuchte Qualitäts-Hersteller für Integrin beta 4 Antikörper. Hier bestellen. ... Monoklonale und polyklonale Integrin beta 4 Antikörper für viele Methoden. ... This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 ... This work investigates alpha6beta4 integrin genetic variations (A380T and R1281W) and breast cancer risk in an Argentinian ...
  http://www.antikoerper-online.de/integrin-complex-pathway-122/integrin-beta-4-antibody-42/
*  Integrin - Wikipedia
The following are 16 of the ~24 integrins found in vertebrates: Beta-1 integrins interact with many alpha integrin chains. Gene ... Integrins are obligate heterodimers, meaning that they have two subunits: α (alpha) and β (beta). Integrins in mammals have ... Wilhelmsen K, Litjens SH, Sonnenberg A. Multiple functions of the integrin alpha6beta4 in epidermal homeostasis and ... Through different combinations of the α and β subunits, around 24 unique integrins are generated. Integrin subunits span the ...
  https://en.wikipedia.org/wiki/Integrin
*  Antiangiogenic gene therapy of cancer: recent developments | Journal of Translational Medicine | Full Text
SiRNA targeted to either subunit of the alpha6beta4 (a laminin adhesion receptor) integrin reduced its cell surface expression ... Marshall JF, Hart IR: The role of alpha v-integrins in tumour progression and metastasis. Semin Cancer Biol. 1996, 7: 129-138. ... Candidate Genes for Antiangiogenic Gene Therapy. At this time, antiangiogenic gene therapy strategies remain in the preclinical ... Maeshima Y, Colorado PC, Kalluri R: Two RGD-independent alpha vbeta 3 integrin binding sites on tumstatin regulate distinct ...
  https://translational-medicine.biomedcentral.com/articles/10.1186/1479-5876-2-22
*  The insulin receptor substrate (IRS) proteins
Identification of insulin receptor substrate 1 (IRS-1) and IRS-2 as signaling intermediates in the alpha6beta4 integrin- ... Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via ... Genes Dev. 2005;19:1773-1778. [PubMed]. 68. Zakikhani M, Blouin MJ, Piura E, Pollak MN. Metformin and rapamycin have distinct ... Activation of a metabolic gene regulatory network downstream of mTOR complex 1. Mol Cell. 2010;39:171-183. [PMC free article] [ ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC3142458/?lang=en-ca
*  Gentaur Molecular :EIAab \ hNaN,Homo sapiens,Human,Peripheral nerve sodium channel 5,PN5,SCN11A,SCN12A,Sensory neuron sodium...
Sodium channel protein type XI subunit alp \ EIAAB37619 for more molecular products just contact us ... Related Genes :. [SCN11A SCN12A SNS2] Sodium channel protein type 11 subunit alpha (Peripheral nerve sodium channel 5) (PN5) ( ... WP1329: Alpha6-Beta4 Integrin Signaling Pathway. WP1371: G Protein Signaling Pathways. WP1772: Apoptosis Modulation and ... Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (hNaN). [BMP4 hCG_20967] Bone ...
  http://www.antibody-antibodies.com/product2888954-search-hNaN,Homo_sapiens,Human,Peripheral_nerve_sodium_channel_5,PN5,SCN11A,SCN12A,Sensory_neuron_sodium_channel_2,SNS2,Sodium_channel_protein_type_11_subunit_alpha,Sodium_channel_protein_type_XI_subunit_alp.html
*  IKBKE - Wikipedia
Mercurio AM (2003). "Invasive skin carcinoma--Ras and alpha6beta4 integrin lead the way". Cancer Cell. 3 (3): 201-2. doi: ... subunit epsilon also known as I-kappa-B kinase epsilon or IKK-epsilon is an enzyme that in humans is encoded by the IKBKE gene ... 2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97 ... "Entrez Gene: IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon". Nomura F, Kawai T, Nakanishi ...
  https://en.wikipedia.org/wiki/IKBKE
*  Gentaur Molecular :EIAab \ CLIA CLMF p35,Cytotoxic lymphocyte maturation factor 35 kDa subunit,IL-12 subunit p35,IL12A,IL-12A...
IL-12 subunit p35,IL12A,IL-12A,Interleukin-12 subunit alpha,Pig,Sus scrofa \ U0059p for more molecular products just contact us ... WP1103: Alpha6-Beta4 Integrin Signaling Pathway. WP1120: Ovarian Infertility Genes. WP1162: Signaling of Hepatocyte Growth ... Cytotoxic lymphocyte maturation factor 35 kDa subunit,IL-12 subunit p35,IL12A,IL-12A,Interleukin-12 subunit alpha,Pig,Sus ... IL-12 subunit p35,IL12A,IL-12A,Interleukin-12 subunit alpha,Pig,Sus scrofa ...
  http://www.antibody-antibodies.com/product3083475-search-CLIA_CLMF_p35,Cytotoxic_lymphocyte_maturation_factor_35_kDa_subunit,IL_12_subunit_p35,IL12A,IL_12A,Interleukin_12_subunit_alpha,Pig,Sus_scrofa.html
*  Collagen-IV and laminin-1 regulate estrogen receptor α expression and function in mouse mammary epithelial cells | Journal of...
Zutter, M. M., Santoro, S. A., Painter, A. S., Tsung, Y. L. and Gafford, A. (1994). The human alpha 2 integrin gene promoter. ... ERα stimulates the expression of α2 integrin subunit. In this regard, ER gene expression has been positively correlated with ... Division of labor among the alpha6beta4 integrin, beta1 integrins, and an E3 laminin receptor to signal morphogenesis and beta- ... α6 and β1 integrin subunits. Our results indicate that integrin-mediated response to specific basement membrane components, ...
  http://jcs.biologists.org/content/116/14/2975
*  Plectin - Wikipedia
In hemidesmosomes plectin has been shown to interact with the integrin β4 subunits of the hemidesmosome plaque and function in ... "Binding of integrin alpha6beta4 to plectin prevents plectin association with F-actin but does not interfere with intermediate ... novel mutations in the beta 4 integrin gene (ITGB4) and genotype/phenotype correlations". Pediatric Research. 49 (5): 618-26. ... The structure of plectin is thought to be a dimer consisting of a central coiled coil of alpha helices connecting two large ...
  https://en.wikipedia.org/wiki/Plectin
*  Plus it
2000) dpy-18 encodes an alpha-subunit of prolyl-4-hydroxylase in caenorhabditis elegans. Genetics 155:1139-1148, pmid:10880476. ... 2003) Recognition of the neural chemoattractant Netrin-1 by integrins alpha6beta4 and alpha3beta1 regulates epithelial cell ... 1994) Mutations in the alpha 2(IV) basement membrane collagen gene of Caenorhabditis elegans produce phenotypes of differing ... In C. elegans, four genes encode collagen P4Hs: dpy-18 (also known as phy-1), phy-2, phy-3, and phy-4 (Friedman et al., 2000; ...
  http://www.jneurosci.org/content/34/49/16348
*  M. Peter Marinkovich, MD | Stanford Medicine Profiles
... but not a cytoplasmic tail-truncated alpha6beta4 integrin. alpha6beta4 integrin does not mediate tumor survival through ... epiligrin cicatricial pemphigoid immunoblot the alpha subunit of laminin 5 but show no reactivity to its beta or gamma subunits ... BP180 gene delivery in junctional epidermolysis bullosa GENE THERAPY Seitz, C. S., Giudice, G. J., Balding, S. D., Marinkovich ... Whether alpha6beta4 integrin regulates migration remains controversial. beta4 integrin-deficient (JEB) keratinocytes display ...
  https://med.stanford.edu/profiles/matt-marinkovich
*  Outline of immunology - Wikipedia
Cell adhesion molecules Integrins - Obligate heterodimers of one alpha and one beta subunits Alpha subunits A1 A2 A3 A4 A5 A6 ... Dimers Cytoadhesin receptor Integrin alpha6beta4 Glycoprotein IIb/IIIa - Heterodimer: ITGA2B / ITGB3 Fibrinogen receptor ... J recombination Artemis complex Recombination-activating gene RAG1 RAG2 Recombination signal sequences Junctional diversity ... Integrin alpha1beta1 Integrin alpha2beta1 Integrin alpha3beta1 VLA-4 - Heterodimer: CD49d / CD29 Alpha-5 beta-1 Integrin ...
  https://en.wikipedia.org/wiki/Outline_of_immunology
*  Paul A. Khavari, MD, PhD | Stanford Medicine Profiles
Blockade of one such hub, the beta1 integrin subunit, disrupted network gene expression and attenuated tumorigenesis in vivo. ... Human cell tumorigenesis is dependent on laminin 5 and alpha6beta4 integrin. Thus, IkappaBalpha circumvents restraints on ... The formation of a stable tetrameric DCoH-HNF-1 alpha complex, which required the dimerization domain of HNF-1 alpha, did not ... 594 genes), in early (159 genes), and in late differentiation (387 genes). Module mapping of 1,046 TFs identified MAF and MAFB ...
  https://med.stanford.edu/profiles/paul-khavari
*  List of MeSH codes (D12.776.543) - Wikipedia
... gtp-binding protein alpha subunits, g12-g13 MeSH D12.776.543.325.100.200 -- gtp-binding protein alpha subunits, gi-go MeSH ... integrin alpha6beta1 MeSH D12.776.543.750.705.876.750 -- integrin alpha6beta4 MeSH D12.776.543.750.705.877.144 -- antigens, ... calcitonin gene-related peptide MeSH D12.776.543.750.720.600.270 -- receptors, cholecystokinin MeSH D12.776.543.750.720.600. ... gtp-binding protein alpha subunits, gq-g11 MeSH D12.776.543.325.100.400 -- gtp-binding protein alpha subunits, gs MeSH D12.776. ...
  https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D12.776.543)