Impressive response to immunotherapy in a metastatic gastric cancer patient: could somatic copy number alterations help patient...
Immunotherapy is an attractive approach for treating patients with cancer, and studies using immunotherapy have shown promising ... Despite reports of promising responses in some patients, immunotherapy is not suitable for all patients; therefore, we explored ... The patient experienced an almost complete response after eleven cycles of treatment. Her symptoms related to the disease ... We present a case of a 50-year-old woman with metastatic GC whose cancer had progressed after first-line chemotherapy and who ...https://jitc.biomedcentral.com/articles/10.1186/s40425-017-0291-9
Preoperative accuracy of gastric cancer staging in patient selection for preoperative therapy: race may affect accuracy of...
Preoperative accuracy of gastric cancer staging in patient selection for preoperative therapy: race may affect accuracy of ... should be considered when selecting gastric cancer patients for preoperative therapy. ... Preoperative accuracy of gastric cancer staging in patient selection for preoperative therapy: race may affect accuracy of ... Preoperative accuracy of gastric cancer staging in patient selection for preoperative therapy: race may affect... ...http://jgo.amegroups.com/article/view/13645
Adjuvant chemoradiotherapy after d2-lymphadenectomy for gastric cancer: the role of n-ratio in patient selection. results of a...
... of gastric cancer patients after surgery according to the UICC stage classification and the general rules for gastric cancer ... Gastric CancerGastric Cancer PatientPerineural InvasionLymphatic Vessel InvasionAdjuvant Chemoradiotherapy ... Adjuvant chemoradiotherapy after d2-lymphadenectomy for gastric cancer: the role of n-ratio in patient selection. results of a ... blood vessel and perineural invasion identifies early-stage high-risk radically resected gastric cancer patients. Br J Cancer ...http://ro-journal.biomedcentral.com.preview-live.oscarjournals.springer.com/articles/10.1186/1748-717X-7-169
Chinese Medical Journal
Treatment selection for gastric cancer in extremely elderly patients.. PMID: 30127226 [PubMed - in process] (Source: Chinese ... Gastrointestinal Stromal Tumors with KIT Mutation Coexisting with Wild-type Gastrointestinal Stromal Tumors in a Patient with ... eg.(cancer,cancers)(cervical,cervix)!("Squamous cell carcinoma",SCC). will return records where either the words 'cancer' or ' ... item_headline "kidney cancer" @item_description (trial,trials). this searches for the phrase 'kidney cancer' in the title as ...https://medworm.com/journal/chinese-medical-journal/
Increased risk of tuberculosis after gastrectomy and chemotherapy in gastric cancer: a 7-year cohort study | SpringerLink
... this relationship has rarely been investigated in patients with gastric... ... Flow chart of case selection of patients with gastric cancer from 2000 to 2006, Taipei Veterans General Hospital. Incidence (A) ... Each patient was followed until 2010 if still alive.. All patients were checked against the registration system of the Centers ... The International Gastric Cancer Association and The Japanese Gastric Cancer Association 2011 ...https://link.springer.com/article/10.1007%2Fs10120-011-0037-1
Nodal Downstaging in Gastric Cancer Patients: Promising Survival if ypN0 is Achieved, Annals of Surgical Oncology | 10.1245...
"Nodal Downstaging in Gastric Cancer Patients: Promising Survival if ypN0 is Achieved, Annals of Surgical Oncology" on DeepDyve ... Preoperative accuracy of gastric cancer staging in patient selection for preoperative therapy: race may affect accuracy of ... Nodal Downstaging in Gastric Cancer Patients: Promising Survival if ypN0 is Achieved. Nodal Downstaging in Gastric Cancer ... Evaluation of the American Joint Committee on Cancer 8th edition staging system for gastric cancer patients after preoperative ...https://www.deepdyve.com/lp/springer_journal/nodal-downstaging-in-gastric-cancer-patients-promising-survival-if-4OOaZNANm1
Biomarkers of Primary Resistance to Trastuzumab in HER2-Positive Metastatic Gastric Cancer Patients: the AMNESIA Case-Control...
Purpose: Refining the selection of HER2-positive metastatic gastric cancer patient candidates for trastuzumab is a challenge of ... Biomarkers of Primary Resistance to Trastuzumab in HER2-Positive Metastatic Gastric Cancer Patients: the AMNESIA Case-Control ... Biomarkers of Primary Resistance to Trastuzumab in HER2-Positive Metastatic Gastric Cancer Patients: the AMNESIA Case-Control ... Biomarkers of Primary Resistance to Trastuzumab in HER2-Positive Metastatic Gastric Cancer Patients: the AMNESIA Case-Control ...http://clincancerres.aacrjournals.org/content/24/5/1082
A systematic review and meta-analysis of gastric cancer treatment in patients with positive peritoneal cytology | SpringerLink
Gastric cancer patients with positive peritoneal cytology as the only marker of metastatic disease have poor prognoses. There ... Selection criteria. The inclusion criteria for the studies were as follows: (1) patients with histologically proven gastric ... bEight patients had S-1; one patient paclitaxel; and one patient nil else ... A systematic review of the accuracy and utility of peritoneal cytology in patients with gastric cancer. Gastric Cancer. 2011;15 ...https://link.springer.com/article/10.1007%2Fs10120-014-0388-5
Home - Journal of Gastrointestinal Oncology
Preoperative accuracy of gastric cancer staging in patient selection for preoperative therapy: race may affect accuracy of ... Intensive care for patients with gastric cancers: outcome and survival prognostic factors Hugo Herrscher, Thierry Artzner, ... Exploring the differences between early-onset gastric cancer and traditional-onset gastric cancer Anwar Giryes, Hani Oweira, ... Supplementation with omega fatty acids increases the mRNA expression level of PLA2G4A in patients with gastric cancer Donya ...http://jgo.amegroups.com
Long-term proton pump inhibitors and risk of gastric cancer development after treatment for Helicobacter pylori: a population...
47 specialist out-patient clinics and 73 general out-patient clinics. All essential clinical information including patients' ... thus minimising the selection, information and recall biases. As all medications are dispensed by the hospital pharmacy at a ... As there may be a delay in the diagnosis of gastric cancer, patients who developed gastric cancer within the first year of H. ... Since gastric cancer can masquerade as non-healing ulcer, all patients with gastric ulcer diagnosed at the time of or any time ...http://gut.bmj.com/content/67/1/28
Her 2 Testing in Indian Patients With Gastric Cancer
Gastric cancer remains a major health issue and a leading cause of cancer death worldwide, although the prevalence and ... The patient will be. de-identified.. 4. Selection of Study Population. Inclusion Criteria:. 100 consecutive patients with ... Test for Her 2 in 100 consecutive gastric cancer patients Immuno-histochemistry will be. done in all patients. Patients with 2 ... Patients will have the Her2 tested in 100 consecutive gastric cancer samples by. immunohistochemistry and patients with 2+ and ...http://www.knowcancer.com/cancer-trials/NCT01814345/
A Study of Genomic-guided 'Standard-of-care' Chemotherapy for in Advanced Gastric Cancer Patients - Full Text View -...
Gastric cancer is a heterogeneous disease with differing chemosensitivities to anti-cancer drugs. Current selection of standard ... Evaluated treatment response of standard-of-care chemotherapy in an enriched patient groups defined as 'responder' based on ... Gastric cancer is the world's second leading cause of cancer death. For patients with unresectable disease or recurrent disease ... The key challenge in managing patients with advanced gastric cancer is to identify the appropriate drugs for patients who might ...https://clinicaltrials.gov/ct2/show/NCT01100801?recr=Open&cond=%22Stomach+Diseases%22&rank=11
Vol 8, No 6 (December 2017) - Journal of Gastrointestinal Oncology
... prevention and clinical investigations of gastrointestinal cancer treatment. ... Preoperative accuracy of gastric cancer staging in patient selection for preoperative therapy: race may affect accuracy of ... Pilot trial of CRLX101 in patients with advanced, chemotherapy-refractory gastroesophageal cancer Joseph Chao, James Lin, Paul ... Heated intraperitoneal chemotherapy and gastrectomy for gastric cancer in the U.S.: the time is now Zachary J. Brown, Jonathan ...http://jgo.amegroups.com/issue/current/showToc
Most recent papers with the keyword Novel Addiction Treatment | Read by QxMD
PURPOSE: Refining the selection of HER2 positive metastatic gastric cancer patients candidates for trastuzumab is a challenge ... The development of medications to treat cocaine use disorders has thus far defied success, leaving this patient population ... Biomarkers of primary resistance to trastuzumab in HER2-positive metastatic gastric cancer patients: the AMNESIA case-control ... read/29208673/biomarkers-of-primary-resistance-to-trastuzumab-in-her2-positive-metastatic-gastric-cancer-patients-the-amnesia- ...https://www.readbyqxmd.com/keyword/73745
Jounce Therapeutics to Present Data from Ongoing ICONIC Trial of JTX-2011 at the 2018 American Society of Clinical Oncology...
The ASCO abstract includes preliminary efficacy data from Phase 1 and 2 patients with gastric cancer and TNBC; pharmacodynamic ... and then identifies related biomarkers designed to match the right therapy to the right patient. Jounce's lead product ... data from Phase 1 that supported Phase 2 dose selection; and safety data from all Phase 2 subjects. ... gastric cancer, triple negative breast cancer (TNBC), head and neck squamous cell cancer (HNSCC) and non-small cell lung cancer ...http://globenewswire.com/news-release/2018/05/16/1507769/0/en/Jounce-Therapeutics-to-Present-Data-from-Ongoing-ICONIC-Trial-of-JTX-2011-at-the-2018-American-Society-of-Clinical-Oncology-Annual-Meeting.html
Highlights of This Issue | Clinical Cancer Research
Optimal Patient Selection for Trastuzumab Treatment in AGC. Ock et al. Page 2520. In HER2 (+) gastric cancer (GC), although ... no biomarker for patient selection has been identified. To define the optimal patients who benefit from trastuzumab, Ock and ... These findings are helpful for optimal patient selection for trastuzumab in HER2(+) GC. ... In all HER2 (+) GC, patients with HER2/CEP17 ratio ≥ 4.48 showed the better OS. Especially, in patients with HER2 IHC ≤ 2+, ...http://clincancerres.aacrjournals.org/content/21/11/2413
Comparison of prognostic nomograms based on different nodal staging systems in patients with resected gastric cancer
Patient characteristics for the multiple imputed datasets are listed in Table S2. The median numbers of MLNs and THNs were 1 ( ... Table 2 shows the MLN-, LNR-, and LODDS-based final Cox models obtained by stepwise backward selection (P , 0.050). The hazard ... The impact of total retrieved lymph nodes on staging and survival of patients with pT3 gastric cancer. Cancer. 2007;110:745-51 ... Gastric Cancer. 2014;17:287-93 19. Lai JF, Kim S, Kim K. et al. Prediction of recurrence of early gastric cancer after curative ...http://jcancer.org/v08p0950.htm
Merck and Pfizer Provide Update on Phase III JAVELIN Gastric 300 Study in Patients With Pre-Treated Advanced Gastric Cancer |...
active chemotherapy comparator rather than placebo in this hard-to-treat patient. population - Safety profile was consistent ... Please go to http://www.merckgroup.com/subscribe to register online, change your selection or discontinue this service.. About ... About Gastric/Gastroesophageal Junction Cancer Globally, gastric cancer is the fifth most common cancer but the third most ... Merck and Pfizer Provide Update on Phase III JAVELIN Gastric 300 Study in Patients With Pre-Treated Advanced Gastric Cancer. ...https://www.perssupport.nl/persbericht/281117117/merck-and-pfizer-provide-update-on-phase-iii-javelin-gastric-300-study-in-patients-with-pre-treated-advanced-gastric-cancer
Failure-to-rescue in patients undergoing surgery for esophageal or gastric cancer
Underlying mechanisms like patient selection, and differences in structure and organization of care should be investigated. ... 2644 patients with esophageal cancer and 1584 patients with gastric cancer were included in this study. In patients with ... in patients with gastric cancer compared to patients with esophageal cancer. CONCLUSION: Once a postoperative complication ... patients with gastric cancer were more likely to die compared to patients with esophageal cancer. ...https://repository.ubn.ru.nl/handle/2066/177731
Abstract 3988: MicroRNA expression associated with response grade in gastric cancer patients' tumors | Cancer Research
... of drug resistance that should manage to determine a predictable miRNA signature to perform a correct patient selection for GC ... Abstract 3988: MicroRNA expression associated with response grade in gastric cancer patients' tumors. Michelle Maccarini ... MicroRNA expression associated with response grade in gastric cancer patients' tumors. [abstract]. In: Proceedings of the 106th ... Abstract 3988: MicroRNA expression associated with response grade in gastric cancer patients' tumors ...http://cancerres.aacrjournals.org/content/75/15_Supplement/3988
Dual Functions of Natural Killer Cells in Selection and Differentiation of Stem Cells; Role in Regulation of Inflammation and...
Impaired IFN-gamma production after stimulation with bacterial components by natural killer cells from gastric cancer patients ... The inability of patient NK cells to contain cancer stem cells potentially due to the flooding of NK cells by proliferating ... NK cell cytotoxic function were also seen in several cancer patients including those of the oral and ovarian cancer patients [ ... Tumor lymphocytes in patients with advanced ovarian cancer: changes during in vitro culture and implications for immunotherapy ...http://www.jcancer.org/v04p0012.htm
Perioperative therapy for locally advanced gastroesophageal cancer: current controversies and consensus of care | Journal of...
For patients undergoing curative intent surgery, advances in perioperative chemotherapy and/or chemoradiotherapy, either before ... Anatomically, GEC is comprised of distal gastric adenocarcinoma (GC), classically associated with Helicobacter Pylori, while ... distal' (GC) cancer has led to diverse inclusion/exclusion criteria for clinical trial enrollment, embodying various ... Gastroesophageal cancer (GEC) remains a challenging problem in oncology. ...https://jhoonline.biomedcentral.com/articles/10.1186/1756-8722-6-66
Analysis of Postoperative Complications Following Laparoscopic Gastrectomy in 1332 Gastric Cancer Patients
... that the beginner can safely perform laparoscopic gastrectomy for stage I gastric cancer through the strict patient selection, ... The laparoscopic gastrectomy is still one of challenging fields for treatment of gastric cancer patient. Morbidity of ... Oh, SY, Kwon, S, and Lee, KG (2014). Outcomes of minimally invasive surgery for early gastric cancer are comparable with those ... Long-term survival results of laparoscopic distal gastrectomy for stage I gastric cancers were not inferior with those of open ...http://www.e-jmis.org/journal/view.html?doi=10.7602/jmis.2018.21.1.1
Theodor Billroth - Wikipedia
But his most famous accomplishment is unquestionably the first successful gastrectomy for gastric cancer. On January 29, 1881, ... with resultant improvements in patient selection. He was appointed professor of surgery at the University of Vienna in 1867, in ... He did not limit himself to surgery only, and conducted extensive research on an ailment that affected many surgery patients at ... He was the first surgeon to excise a rectal cancer and by 1876, he had performed 33 such operations. By 1881, Billroth had made ...https://en.wikipedia.org/wiki/Theodor_Billroth
Somatic evolution in cancer - Wikipedia
... gastric cancer, bile duct cancer, pancreatic cancer, small intestine cancer and colon cancer. In the colon, a field defect ... Clonal expansion is the signature of natural selection in cancer. Cancer therapies act as a form of artificial selection, ... November 1999). "Multiple clonal abnormalities in the bronchial epithelium of patients with lung cancer". J. Natl. Cancer Inst ... "The mutation spectrum revealed by paired genome sequences from a lung cancer patient". Nature. 465 (7297): 473-7. doi:10.1038/ ...https://en.wikipedia.org/wiki/Somatic_evolution_in_cancer