*  Endogenous retrovirus - Wikipedia
Viruses portal Avian sarcoma leukosis virus (ASLV) Endogenous viral element ERV3 HERV-FRD Horizontal gene transfer Jaagsiekte ... Reverse transcriptase functions to synthesize viral DNA from the viral RNA in the host cell's cytoplasm before it entering the ... "Reactivated Virus May Contribute to ALS". Yolken R (June 2004). "Viruses and schizophrenia: a focus on herpes simplex virus". ... Murine leukemia virus (MLV) and xenotropic murine leukemia virus-related virus (XMRV) Paleovirology Belshaw R, Pereira V, ...
  https://en.wikipedia.org/wiki/Endogenous_retrovirus
*  A Charged Second-Site Mutation in... preview & related info | Mendeley
... family of retroviruses requires first a specific interaction between the viral surface (SU) glycoproteins and a receptor on the ... The entry process of the avian sarcoma and leukosis virus (ASLV) ... The entry process of the avian sarcoma and leukosis virus (ASLV ... that the cysteines flanking the internal fusion peptide in ASLV TM are critical for efficient function of the ASLV viral ... A Charged Second-Site Mutation in the Fusion Peptide Rescues Replication of a Mutant Avian Sarcoma and Leukosis Virus Lacking ...
  https://www.mendeley.com/research-papers/charged-secondsite-mutation-fusion-peptide-rescues-replication-mutant-avian-sarcoma-leukosis-virus-l/
*  Env (gene) - Wikipedia
"Low pH is required for avian sarcoma and leukosis virus Env-dependent viral penetration into the cytosol and not for viral ... of the virus is determined by the SU protein domain because it is responsible for the receptor-binding function of the virus. ... The Env proteins of the Avian Sarcoma and Leukosis virus (ASLV) and the Murine Leukemia Virus (MLV) are both trimers of SU-TM ... Avian Sarcoma and Leukosis Viruses (ASLV) have ten subgroups (A through J). The envelope glycoprotein of subgroup A is called ...
  https://en.wikipedia.org/wiki/Env_(gene)
*  Insertional mutagenesis - Wikipedia
Avian leukosis virus is an example of a virus that causes a disease by insertional mutagenesis. Newly hatched chicks infected ... The virus inserts a gene (known as a viral onocogene) normally near the cellular myc (c-myc)gene. The c-myc gene is normally ... Hence, when a genetic region is interrupted by integration of pBR322, the gene function is lost but new gene function ( ... with Avian leukosis virus will begin to form tumours that will begin to appear in their bursa of fabricus (like the human ...
  https://en.wikipedia.org/wiki/Insertional_mutagenesis
*  Going viral? Linking the etiology of human prostate cancer to the PCA3 long noncoding RNA and oncogenic viruses | EMBO...
An interesting example in the poultry industry is the integration of several related avian leukosis viruses with miRNAs and ... the biological function of PCA3 remained elusive for almost two decades after its discovery (Bussemakers et al, 1999), until we ... Going viral? Linking the etiology of human prostate cancer to the PCA3 long noncoding RNA and oncogenic viruses. Andre A ... In addition, random viral insertions can lead to the formation of virus‐host chimeric functional units (e.g., lncRNAs) that are ...
  http://embomolmed.embopress.org/content/early/2017/07/27/emmm.201708072.long
*  Avian herpesvirus amplicon as a eucaryotic expression vector - Patent # 4996152 - PatentGenius
The amplicons are also useful for inserting associated genes into the helper viruses, which in turn could be used as expression ... disease viruses of poultry. Concatmers of the seeds and the associated genes have potential as vaccines or delivery vectors ... when cotransfected and replicated in the presence of helper viruses. ... a fragment of viral DNA which contains all cis-acting functions required for DNA replication. In the presence of helper virus ...
  http://www.patentgenius.com/patent/4996152.html
*  "Virus-Host Interactions in the Development of Avian Leukosis Virus-Ind" by Rosalinda Gram Foster
The effect of virus infection on osteoblast function was examined in the diseased bone and in osteoblast cultures. In infected ... Osteopetrotic bone contained higher levels of viral DNA and correspondingly higher levels of viral proteins than infected ... suggesting an atypical life cycle of the virus in the infected osteoblasts. To better understand virus-host interactions in the ... In culture, virus infection had no apparent effect on either the proliferation or differentiation of osteoblasts. This ...
  http://escholarship.umassmed.edu/gsbs_diss/180/
*  Retroviral mRNA nuclear export elements regulate protein function and virion assembly | The EMBO Journal
Nasioulas G, Hughes SH, Felber BK, Whitcomb JM (1995) Production of avian leukosis virus particles in mammalian cells can be ... Other viruses such as hepatitis C virus, herpesviruses and poxviruses have been shown to assemble in viral factories where the ... Perturbation of the RNA export element of avian leukosis virus (ALV) has been associated with budding and genome packaging ... Freed EO (1998) HIV‐1 gag proteins: diverse functions in the virus life cycle. Virology 251: 1-15. ...
  http://emboj.embopress.org/content/23/13/2632
*  Bursal Disease - Marek's Disease Vaccine, Serotype 3, Live Marek's Disease Vector - Environmental Assessment for Licensing in...
... modified to express an antigenic protein of infectious bursal disease virus. This vaccine is administered to healthy chicken ... Bursal tumours are relatively rare, helping to differentiate MD from avian lymphoid leukosis. The serologically related, non- ... viral polyadenylation signal sequences. Details of the source, description and function of the foreign genetic material are on ... Avian telomeric regions contain repeats of the sequence TTAGGG; this same sequence is present in the genomes of MD viruses, ...
  http://www.cfia-acia.agr.ca/animals/veterinary-biologics/licensed-products/environmental-assessments/bursal-disease-marek-s-disease/eng/1342098172373/1342098313775
*  Chronic myocarditis | definition of chronic myocarditis by Medical dictionary
Chronic myocarditis and circulatory syndrome in a white leghorn strain induced by an avian leukosis virus: light and electron ... low replicative terminally deleted viral forms could be generated and selected in heart tissues during the early acute viral ... In majority of the cases where insult to myocardium is limited, the heart function recovers within a few months, but in cases ... Sero-prevalence and Pathological Examination of Lymphoid Leukosis Virus Subgroup A in Chickens in Anhui Province, China ...
  http://medical-dictionary.thefreedictionary.com/chronic+myocarditis
*  Three decades of Wnts: a personal perspective on how a scientific field developed | The EMBO Journal
Analysis of avian leukosis virus DNA and RNA in bursal tumours: viral gene expression is not required for maintenance of the ... Bishop JM, Varmus H (1985) Functions and origins of retroviral transforming genes. InRNA Tumor Viruses Weis R, Teich N, Varmus ... cell lymphomas caused by the slowly oncogenic Avian Leukosis Virus (ALV) commonly contained proviruses inserted near the c‐myc ... Cohen JC, Shank PR, Morris VL, Cardiff R, Varmus HE (1979) Integration of the DNA of mouse mammary tumor virus in virus‐ ...
  http://emboj.embopress.org/content/31/12/2670
*  Leukemia | definition of leukemia by Medical dictionary
The persistent lymphocytosis that occurs in some cattle is a response to infection with the bovine viral leukosis virus. ... At first, leukemia cells function almost normally. In time, they may crowd out normal white blood cells, red blood cells, and ... avian leukemia. see avian leukosis.. basophilic leukemia, basophilocytic leukemia. leukemia in which basophilic granulocytes ... Of primary concern are those symptoms attendant to suppression of normal bone marrow function, particularly susceptibility to ...
  http://medical-dictionary.thefreedictionary.com/leukemia
*  Vaccinia‐Based Reporter Gene Cell‐Fusion Assays to Quantitate Functional Interactions of HIV Envelope Glycoprotein with...
Mutational analysis of the candidate internal fusion peptide of the avian leukosis and sarcoma virus subgroup A envelope ... The transmembrane domain in viral fusion: Essential role for a conserved glycine residue in vesicular stomatitis virus G ... Sequential CD4‐coreceptor interactions in human immunodeficiency virus type 1 Env function: Soluble CD4 activates Env for ... Construction and use of a human immunodeficiency virus vector for analysis of virus infectivity. J. Virol. 64:5270‐5276. ...
  http://www.currentprotocols.com/WileyCDA/CPUnit/refId-im1210.html?quicktabs_cp=materials
*  Patent US6639052 - Human ADA2 polypeptides - Google Patents
... spleen necrosis virus, retroviruses such as Rous Sarcoma Virus, Harvey Sarcoma Virus, avian leukosis virus, gibbon ape leukemia ... An agonist is a compound which increases the natural biological functions, while antagonists eliminate such functions. As an ... viral DNA such as vaccinia, adenovirus, fowl pox virus, and pseudorabies. However, any other vector may be used as long as it ... virus, human immunodeficiency virus, adenovirus, Myeloproliferative Sarcoma Virus, and mammary tumor virus. In one embodiment, ...
  http://www.google.com/patents/US6639052?dq=3657699
*  Genes and Genome of HIV-1 | OMICS International
It is enclosed by viral nucleocapsid (NC) protein, or p24. There are some in the virus layer and typically 7 internal proteins ... 12] have informed that CpG methylation in Avian Leukosisvirus favour the integration process [5].. ... The binding of phospholipids with these factors are useful for MA to perform the function. The self association of Gag and Gag- ... Viral proteins are processed by viral proteases: some of the viral proteins are moved to the host plasma membrane. Mature ...
  https://www.omicsonline.org/open-access/genes-and-genome-of-hiv-2329-9002-2-126.php?aid=27166
*  Discovery of endogenous viruses | Philosophical Transactions of the Royal Society B: Biological Sciences
1971 An avian leukosis virus related to RSV(0): properties and evidence for helper activity. Virology 43, 223-234. (doi:10.1016 ... For small DNA tumour viruses, the full replication cycle occurs via non-integrated circular viral genomes, whereas viral ... Again, there are multiple copies of MMTV in the murine genome [31], some of which encode super-antigen functions that induce ... Marek's disease virus [65] and the related turkey virus. REV has also been found in the genome of fowlpox virus [66], a virus ...
  http://rstb.royalsocietypublishing.org/content/368/1626/20120494
*  Avian immune system - Wikipedia
The most common immunosuppressive viruses are Infectious Bursal Disease Virus (IBDV), Avian Leukosis, Marek's Disease (MD) and ... Various bird organs function to differentiate avian immune cells: the thymus, Bursa of Fabricius and bone marrow are primary ... The innate immune response is known to be essential for viral infection and as a result, the publication of the full chicken ... "Development of the Avian Immune System." Avian Immunology. 4:51-66. Masteller EL, Pharr GT, Funk PE, Thompson CB (1997). "Avian ...
  https://en.wikipedia.org/wiki/Avian_immune_system
*  Astrocytes Give Rise to New Neurons in the Adult Mammalian Hippocampus | Journal of Neuroscience
... of the RCAS avian leukosis virus under the GFAP promoter (Holland and Varmus, 1998). Previous work has shown that infection of ... AP-positive cells identified after injection of RCAS-AP virus into the dentate gyrus of Gtva mice in eand d 2 d after viral ... To directly show that GFAP-expressing cells in the SGL function as neuronal precursors in animals not exposed to APB, we used ... When avian RCAS virus carrying the alkaline phosphatase reporter gene (RCAS-AP) was injected into the dentate gyrus of adult ...
  http://www.jneurosci.org/content/21/18/7153.long
*  Leukeamia | Article about Leukeamia by The Free Dictionary
Avian leukosis occurs in countries with advanced poultry farming and causes great economic damage. The causative agent of the ... any of a group of proteins produced by cells in the body in response to an attack by a virus. A cell infected by a virus ... viral, and viral-genetic-the last has gained the widest acceptance. However, the matter has not been conclusively settled. ... Frequent infections result from a dearth of functioning white blood cells. Bone tenderness may also be present. Hemorrhaging ...
  https://encyclopedia2.thefreedictionary.com/Leukeamia
*  retrovirus facts, information, pictures | Encyclopedia.com articles about retrovirus
avian leukosis virus. birds. malignancies. Beta-retrovirus. intracytoplasmic assembly. mouse mammary tumor virus. mice. mammary ... The remarkable replication pathway of retroviruses requires that once the virus enters the host cell, a viral pol gene-encoded ... Following integration, the provirus behaves like a set of cellular genes, while the LTRs function as promoters that begin ... Full-length viral mRNA is transported to the cytoplasm where it is either packaged into progeny virus or translated on non- ...
  https://www.encyclopedia.com/plants-and-animals/microbes-algae-and-fungi/moneran-and-protistan/retrovirus
*  KAKEN - Research Projects | Investigation of the genes associated with tumorigenicity of Marek's disease virus. (KAKENHI...
MDCC-MSBI(MSBI). but not that of the avian lymphoid leukosis-derived lymphoblastoid cell line, LSCC-BK3. Colony formation in ... However, direct proof of the function of the 1.8 kb gene has been lacking. We examined the role of the 1.8 kb gene in ... Although maintenance of latent infection of MDV seems to involve mechanisms regulating viral transcription, it is not clear ... Marek's disease virus (MDV) is an avian herpesvirus which induces lymphoproliferative disease in chickens. It has been ...
  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-02660301/
*  Joseph (Joe) Lipsick | Stanford Medicine Profiles
To accomplish this, we constructed dominantly selectable avian leukosis virus derivatives which efficiently coexpress the ... Both viral Myb (v-Myb) and cellular Myb (c-Myb) are nuclear sequence-specific DNA-binding proteins that can function as ... The defective acute leukemia viruses avian myeloblastosis virus (AMV) and E26 virus each contain an inserted cellular sequence ... AVIAN-MYELOBLASTOSIS VIRUS AND E26 VIRUS ONCOGENE PRODUCTS ARE NUCLEAR PROTEINS PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES ...
  https://med.stanford.edu/profiles/joseph-lipsick
*  University of Pennsylvania || School of Medicine || Paul F. Bates, PhD
Chai Ning, Bates Paul: Na+/H+ exchanger type 1 is a receptor for pathogenic subgroup J avian leukosis virus. Proceedings of the ... protein down-regulation by ebolavirus represents a novel mechanism for a viral glycoprotein affecting host cell function and ... Hantaan Virus, Rift Valley Fever Virus, Andes virus and Sin Nombre Virus.. Ebolavirus infection is associated with a high ... Kaletsky Rachel L, Simmons Graham, Bates Paul: Proteolysis of the Ebola virus glycoproteins enhances virus binding and ...
  http://www.med.upenn.edu/apps/faculty/index.php/g20000161/p17408
*  Frontiers | Interplay between the alpharetroviral Gag protein and SR Proteins SF2 and SC35 in the nucleus | Microbiology
The integrated provirus is used as a template for the transcription of viral RNA. The full-length viral RNA can be used for the ... The mechanism by which Gag selectively incorporates unspliced gRNA into virus particles is poorly understood. Although Gag was ... The integrated provirus is used as a template for the transcription of viral RNA. The full-length viral RNA can be used for the ... The mechanism by which Gag selectively incorporates unspliced gRNA into virus particles is poorly understood. Although Gag was ...
  https://www.frontiersin.org/articles/10.3389/fmicb.2015.00925/full
*  FOOT AND MOUTH DISEASE VIRUS (FMDV) CONSENSUS PROTEINS, CODING SEQUENCES THEREFOR AND VACCINES MADE THEREFROM - Patent...
... a Moloney virus promoter, an avian leukosis virus (ALV) promoter, a cytomegalovirus (CMV) promoter such as the CMV immediate ... As is known in the art, variation in this distance may be accommodated without loss of promoter function. [0065] r. Promoter [ ... The empty viral capsid proteins VP1-4 of the FMDV antigen provides an entire repertoire of immunogenic sites and epitopes ... virus (MMTV) promoter, a human immunodeficiency virus (HIV) promoter such as the bovine immunodeficiency virus (BIV) long ...
  http://www.patentsencyclopedia.com/app/20120282217