*  Patente US4925787 - Monoclonal anti-idiotypic antibody, method for production thereof, and ... - Google Patentes
... of producing a monoclonal anti-idiotypic antibody specific to the human IgG1 type monoclonal antibody possessing specificity to ... and collecting the produced monoclonal anti-idiotypic antibody; and use of the monoclonal anti-idiotypic antibody as a reagent ... monoclonal anti-idiotypic antibody by the steps of immunizing an animal with a human IgG1 type monoclonal antibody specific to ... propagating the selected hybridoma thereby giving rise to said monoclonal anti-idiotypic antibody, ...
  http://www.google.es/patents/US4925787
*  MARIAN ELLIOTT KOSHLAND | Biographical Memoirs: Volume 90 | The National Academies Press
T T K O S H L A N D MARIAN ELLIO 233 1967 Location of specificity and allotypic amino acid residues in antibody Fd fragments. ... quisitely careful amino acid composition analyses, convincingly showed that these antibodies had different amino acid ... Differences in amino acid composition related to allotypic and antibody specificity of rabbit heavy chains. Immunochemistry 5: ... Differences in amino acid composition of two purified antibodies from the same rabbit. Proc. Natl. Acad. Sci. U. S. A. 50:61-68 ...
  https://www.nap.edu/read/12562/chapter/11
*  Recombinant Human Antibodies Against Aldehyde-Modified Apolipoprotein B-100 Peptide Sequences Inhibit Atherosclerosis |...
... amino acids 661 to 680) or P210 (KTTKQSFDLSVKAQYKKNKH, amino acids 3136 to 3155) were selected from the single-chain fragment- ... A total of 4 scFv with specificity for the MDA-modified apoB-100 peptide composed of amino acids 661 to 680 (IEI-A8, IEI-D8, ... 11 Single-chain human antibody fragments with specificity for MDA-modified apoB-100-derived peptides P45 (IEIGLEGKGFEPTLEALFGK ... P2 (amino acids [aa] 16 to 31, red), P45 (aa 661 to 680, blue), P143 (aa 2131 to 2150, orange), P210 (aa 3136 to 3155, purple ...
  http://circ.ahajournals.org/content/110/14/2047
*  Plus it
A recombinant fragment of rabphilin [amino acid (aa) 1-361] was expressed and purified from bacteria in its wild-type form (WT ... A large proportion of rabphilin is phosphorylated on S234 after a 2 min high K+ stimulation.A, Specificity of the antibody ... Briefly, a peptide corresponding to amino acids 230-239 (TRRASEARMS) of rabphilin was synthesized with an additional cysteine ... Equal amounts of rabphilin wild-type fragment (WT), wild-type fragment phosphorylated by PKA (WT/PKA), and each of the two ...
  http://www.jneurosci.org/content/21/15/5473
*  Aberrant expression of minichromosome maintenance proteins 2 and 5, and Ki-67 in dysplastic squamous oesophageal epithelium and...
Anti-Mcm2 monoclonal antibody (mAb) (mouse IgG1 isotype) was raised against a fragment of human Mcm2 (amino acids 725-888; BM28 ... Specificity of anti-Mcm2 mAb and anti-Mcm5 polyclonal antibody was established by immunoblot, immunofluorescence, and ... Rabbit polyclonal antibodies were raised against a fragment of human Mcm5 (amino acids 372-590) and purified by affinity ... Immunostaining with the Mcm2 antibody yielded predominantly nuclear staining. The Mcm5 antibody stained nuclei but also cell ...
  http://gut.bmj.com/content/50/3/373
*  Monoclonal antibody therapy - Wikipedia
... which consist of three antibody hypervariable amino acid domains responsible for the antibody specificity embedded into ... fragment-antigen binding) part can be separated from the Fc (fragment constant) part of the molecule. The Fab fragments contain ... Humanised antibodies are produced by grafting murine hypervariable regions on amino acid domains into human antibodies. This ... Immunoliposomes have been successfully used in vivo to convey tumour-suppressing genes into tumours, using an antibody fragment ...
  https://en.wikipedia.org/wiki/Monoclonal_antibody_therapy
*  Improved scFv Anti-HIV-1 p17 Binding Affinity Guided from the Theoretical Calculation of Pairwise Decomposition Energies and...
The new antibodies were designed by mutating the potential amino acid residues in CDRs of scFv anti-p17. With the guide from ... Single chain Fv fragments display the binding specificity, monovalent binding affinity of full-size antibodies, and provide the ... Potential amino acids that involved changing nonalanine amino acids into alanines will be listed up. The relevant change of ... One type of genetically engineered antibody is the single chain Fv fragment (scFv). Single chain Fv fragments are genetically ...
  https://www.hindawi.com/journals/bmri/2013/713585/
*  US Patent # 9,770,011. Veterinary composition and methods for non-surgical neutering and castration - Patents.com
The term "donor antibody" refers to an antibody (e.g., monoclonal or recombinant) which contributes the amino acid sequences of ... which retains the same antigen binding specificity and/or neutralizing ability as the antibody from which the fragment was ... pyroglutamic acid; # = amide; Underlined amino acid differ from GnRH-I amino acid sequence. GnRH has the same amino acid ... Complete canine antibody heavy chain amino acid sequence (variable heavy sequence (SEQ ID NO: 14) fused to antibody constant ...
  http://patents.com/us-9770011.html
*  GENE RECOMBINANT ANTIBODY AND ANTIBODY FRAGMENT THEREOF - Patent application
... and the amino acid sequence of the CDR regulates binding reactivity and binding specificity of the antibody (J. Exp. Med., 132 ... in the amino acid sequence represented by SEQ ID NO:16. Antibodies and antibody fragments in which one or more amino acids are ... 0124] aspartic acid, glutamic acid, isoaspartic acid, isoglutamic acid, 2-aminoadipic acid, 2-aminosuberic acid; Group C: [0125 ... has the amino acid sequence of human antibody κ class. [0136] A human CDR-grafted antibody is an antibody in which CDR amino ...
  http://www.patentsencyclopedia.com/app/20120276090
*  Patent US6372957 - Transgenic mouse comprising a MEF2 binding site operatively linked to an ... - Google Patents
A HDAC5 deletion mutant lacking amino acids 22-488 (HDAC5-ΔN), including the 18-amino acid minimal MEF2-interactin region, ... Single-chain antibody variable fragments (Fvs) in which the C-terminus of one variable domain is tethered to the N-terminus of ... Immunohistological analysis for the expression of a transgene by using an antibody of appropriate specificity can be performed ... Once the component amino acids of the turn are determined, mimetics can be constructed to achieve a similar spatial orientation ...
  http://www.google.com/patents/US6372957?dq=7125605
*  Type-specific immunogenicity of a chemically synthesized peptide fragment of type 5 streptococcal M protein. | JEM
The synthetic peptides, designated S-M5(1-20) and S-M5(20-40), represent the amino-terminal amino acid sequence of the native ... antibodies in rabbits without evoking heart cross-reactive antibodies. ... We determined the antigenic specificity and protective immunogenicity of two chemically synthesized peptides of type 5 ... Type-specific immunogenicity of a chemically synthesized peptide fragment of type 5 streptococcal M protein.. J B Dale, J M ...
  http://jem.rupress.org/content/158/5/1727
*  Anti-VDAC1 / PORIN Antibody (aa1-211) for IHC, WB/Western LS-C186351
PORIN antibody LS-C186351 is an immunoaffinity-purified rabbit polyclonal that binds aa1-211 of human PORIN (also known as ... VDAC1 / PORIN antibody was raised against recombinant fragment corresponding to a region within amino acids 1 and 211 of VDAC1 ... Specificity:. Human PORIN / VDAC-1. Usage:. IHC-paraffin: Suggested antigen retrieval using heat mediated 10 mM Citrate buffer ... VDAC1 Antibody, HVDAC1 Antibody, Plasmalemmal porin Antibody, Porin 31HM Antibody, PORIN Antibody, PORIN-31-HL Antibody, Vdac5 ...
  https://www.lsbio.com/antibodies/anti-vdac1-antibody-porin-antibody-aa1-211-ihc-wb-western-ls-c186351/194003
*  NOVEL CHEMICAL COMPUNDS AND THEIR USE - BIOTA SCIENTIFIC MANAGEMENT PTY LTD
... wherein the fragments retain the binding specificity of the whole antibody molecule. The binding fragments include, for example ... 4) Suzuki, H.; Kajimoto, Y.; Kumagai, H. Improvement of the Bitter Taste of Amino Acids through the Transpeptidation Reaction ... Also included for moiety X are antibodies or antigen binding fragments of whole antibody, ... introduction of a glucuronic acid residue or a lipophile-modified version of glucuronic acid HO OH UDP-glucuronic acid 0 ooh ...
  http://www.sumobrain.com/patents/wipo/Novel-chemical-compunds-their-use/WO2004050677.html
*  US20080292618A1 - Intranuclear protein transduction through a nucleoside salvage pathway - Google Patents
... antibody mAb 3E10, and variants and/or functional fragments thereof. The nucleotide and amino acid sequences for the variable ... As used herein, the phrase "functional fragments of an antibody having the binding specificity of the antibody as produced by ... The free amino group (at the amino terminus of a protein or on a lysine) in amino acid residues may be reacted with a compound ... Thus, in certain embodiments, a functional fragment of an antibody having the binding specificity of the antibody as produced ...
  https://patents.google.com/patent/US20080292618A1/en
*  Characterization of the Borna disease virus phosphoprotein, p2...
Borna disease virus infection is diagnosed by the presence of serum antibodies reactive with t ... Although p40 and p23 are unrelated in amino acid sequence structure, cross-reactive antibodies are described. Protein fragments ... and synthetic peptides were analyzed to characterize the specificities of antibodies to p23. Epitope mapping revealed eight ... None of these epitopes was reactive with antibodies to p40. Cross-reactivity with monospecific sera and monoclonal antibodies ...
  https://www.mysciencework.com/publication/show/characterization-of-the-borna-disease-virus-phosphoprotein-p23
*  Connective tissue growth factor antibodies - FibroGen, Inc.
The antibodies are particularly directed to regions of CTGF involved in biological activities associated with fibrosis. The ... The present invention relates to antibodies that bind to CTGF. ... A polypeptide or amino acid fragment is any portion of a ... Substitution of the Fv CDRs of an antibody having specificity for a non-CTGF antigen will create a chimeric antibody comprising ... amino acid 201 to amino acid 242 of SEQ ID NO:2, amino acid 247 to amino acid 349 of SEQ ID NO:2, amino acid 248 to amino acid ...
  http://www.freepatentsonline.com/9034643.html
*  Cytokeratin 19 Antibody (4E12) (NBP1-48278): Novus Biologicals
Mouse Monoclonal Anti-Cytokeratin 19 Antibody (4E12). Epithelial Cell Marker. Validated: WB, IHC, IHC-P. Tested Reactivity: ... Cytokeratin 19 Antibody (4E12) Summary. Immunogen. Recombinant fragment expressed in E.coli corresponding to amino acids 240- ... Specificity. This antibody is specific for Homo sapiens keratin 19 (KRT19).. Isotype. IgG1 ... Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody! Or feel free ...
  https://www.novusbio.com/products/cytokeratin-19-antibody-4e12_nbp1-48278
*  Exbio antibodies - Mouse Monoclonal to ARHGEF4 / ASEF1 ARHGEF-08 (IgG1)
Recombinant fragment of human ARHGEF4 (amino acids 143-271). Species Reactivity: *Human ... Specificity The mouse monoclonal antibody ARHGEF-08 recognizes human intracellular protein ARHGEF4 / ASEF1, approx. 80 kDa ...
  http://www.exbio.cz/products/clone.py?idclone=CLO000000000000523
*  HYBRID ANTIBODIES - Patent application
... amino acid sequences contained in a reference database of antibody sequences or antibody fragment sequences from a target ... 18. A hybrid antibody or antibody fragment made by a method comprising: providing an initial antibody having specificity for a ... antibody or hybrid antibody fragment is specific for said target. 6. The hybrid antibody or hybrid antibody fragment according ... a library of antibodies or antibody fragments is provided which includes hybrid antibodies and/or hybrid antibody fragments ...
  http://www.patentsencyclopedia.com/app/20110230646
*  Functional analysis of parvin and different modes of IPP-complex assembly at integrin sites during Drosophila development |...
... antibody using the GST-tagged fusion protein corresponding to parvin amino acids 1-241 after cloning of the BamHI-XbaI fragment ... Antibody specificity was tested by western blotting and immunohistochemistry in both wild-type and parvin mutant embryos, as ... 1B). The parvin251 line results in the elimination of the first 89 amino acids of parvin, whereas parvin694 removes almost the ... Below: lines represent amino acids, shaded to illustrate conservation: black, identical in all species; gray, similar; white, ...
  http://jcs.biologists.org/content/125/13/3221.long
*  Patent US7632500 - Monoclonal antibodies against HMGB1 - Google Patents
... the present invention is drawn to antibodies or antigen-binding fragments thereof that bind to a vertebrate high mobility group ... the invention is an antibody or antigen-binding fragment that binds to a peptide consisting of amino acid residues 46 to 63 of ... the antibody or antigen-binding fragment has the epitopic specificity of an antibody or antigen-binding fragment selected from ... 9 to about 50 amino acids, 9 to about 40 amino acids, 9 to about 30 amino acids, 9 to about 25 amino acids or 9 to about 20 ...
  http://www.google.ca/patents/US7632500
*  Myogenin Antibody (MGN185 + F5D) [PerCP] (NBP2-34684PCP): Novus Biologicals
Mouse Monoclonal Anti-Myogenin Antibody (MGN185 + F5D) [PerCP]. Skeletal Muscle Marker. Validated: WB. Tested Reactivity: Human ... Human myogenin recombinant protein (MGN185); Rat myogenin recombinant fragment containing amino acid 30-224 (F5D) ... Specificity. Myogenin is a member of the MyoD family of myogenic basic helix-loop-helix (bHLH) transcription factors that also ... The regulatory domain of MyoD is approximately 70 amino acids in length and includes both a basic DNA binding motif and a bHLH ...
  https://www.novusbio.com/products/myogenin-antibody-mgn185-f5d_nbp2-34684pcp
*  Anti-IL1RAP Antibodies and Their Use for Treating Human - CANTARGIA AB
The present invention provides agents comprising or consisting of a binding moiety with specificity for interleukin-1 receptor ... as well as chimaeric antibodies, humanised antibodies, human antibodies (wherein at least one amino acid is mutated relative to ... For example, the agent may comprise or consist of an antibody or an antigen-binding fragment thereof with binding specificity ... Methods of generating antibodies and antibody fragments are well known in the art. For example, antibodies may be generated via ...
  http://www.freepatentsonline.com/y2017/0081414.html
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
Peptides with these amino acid sequences were synthesized and used to immunize rabbits for the production of antibodies. The ... All antibodies showed remarkable specificity against the viral sequences as evidenced by the observation that no cross- ... Tetanus Toxin Hc Fragment Induces the Formation of Ceramide Platforms and Protects Neuronal Cells against Oxidative Stress. ... Amino Acids, Peptides, and Proteins, lipid-protein interaction, channel reconstitution, lipid-dependent gating, voltage-gated ...
  https://www.jove.com/visualize/abstract/23826362/tetanus-toxin-hc-fragment-induces-formation-ceramide-platforms
*  A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes | JCB
To generate anti-Gli antibodies, two fragments of the human Gli3 protein (an N-terminal fragment consisting of amino acids 1- ... S1 shows the specificity of novel polyclonal antibodies used for immunofluorescence. Fig. S2 shows the effects of oxysterols, ... For the anti-Smo antibody, a fragment of the intracellular C-terminal domain of mouse Smo (amino acids 683-794) was expressed ... 799 and a C-terminal fragment consisting of amino acids 1,061-1,599) were expressed in bacteria as insoluble 6His-MBP-tagged ...
  http://jcb.rupress.org/content/191/2/415.full