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*  Patent US2659368 - Extracorporeal circulation device - Google Patents
NovTT7, 1953 J. H. GIBBON, JR, E'TAL ,368 EXTRACORPOREAL CIRCULATION DEVICE Filed May 28, 1949 16 Sheets-Sheet 1 INVENTORS .hmv bf Gaga/1.17., 'w'rnv MA. Mamas ATTORNEY J. H. GIBBON, JR, ETAL 2,659,368 EXTRACORPOREAL CIRCULATION DEVICE Nov. 17, 1953 16 Sheets-Sheet 2 Filed May 28, 1949 Nov. 17, 1953 J. H. GIBBON, JR, ET AL I EXTRACORPOREAL CIRCULATION DEVICE Filed May 28, 1949 16 Sheets-Sheet 5 FIG. 5 FIG? 5 mm H {R Tfll N R i m mu .T Q W MZ Mm? W my 4 m Nov. 17, 1953 J. H. GIBBON, JR., ET AL 2,559,368 EXTRACORPOREAL CIRCULATION DEVICE Filed May 28, 1949 16 Sheets-Sheet 6 INVENTORS la/w 1% 67.950 J2, Gus/7w K17. MAI/V845 Jo/r/v A [was/Away; Kama/v a A [max/9.1;. ATTORNEY Nov. 17, 1953 J. H. GIBBON,IJR., ET AL v ,3 8 EXTRACORPOREAL CIRCULATION DEVICE (Z FIG. ...
  http://www.google.com/patents/US2659368?dq=assignee:+google
*  High-Dose Radioimmunotherapy Combined With Extracorporeal Depletion in a Syngeneic Rat Tumor Model | MAD for Cancer
BACKGROUND: The aim of the current study was to investigate the possibility of increasing the maximal tolerated dose (MTD) of a tumor-selective radiolabeled antibody when radioimmunotherapy (RIT) is combined with extracorporeal depletion of radioimmunoconjugates from the circulation. Furthermore, the authors evaluated whether this increase in dose improved the therapeutic effect on solid manifest tumors in an immunocompetent animal model. METHODS: Rats were injected with high activities/body weight of lutetium (Lu-177)- or yttrium (Y-90)-labeled antibody conjugates (monoclonal antibody tetraazacyclododecanetetraacetic acid-biotin) and subjected to removal of the conjugate from the circulation by extracorporeal affinity adsorption treatment 24 hours postinjection. Myelotoxicity was assessed by analysis of blood parameters for 12 weeks. The effect of increased doses in combination with ...
  https://www.madforcancer.lu.se/sven-erik-strand/publication/b92f2ae8-0866-4f92-9e2c-798978a92649
*  Mau funcionamento do sistema de circulação extracorpórea: relato de caso
ALMEIDA, Carlos Eduardo David de et al. Malfunction of the extracorporeal circulation system: case report. Rev. Bras. Anestesiol. [online]. 2011, vol.61, n.6, pp.781-785. ISSN 0034-7094. http://dx.doi.org/10.1590/S0034-70942011000600010.. BACKGROUND AND OBJECTIVES: The introduction of extracorporeal circulation in clinical practice was decisive for the development of modern cardiovascular surgery. Addition of new procedures and equipment, however, brings inherent risks and complications. The objective of this report is to describe a malfunction of the oxygenation system and emphasize the importance of the interaction among the medical team members to prevent errors and complications. CASE REPORT: During valve replacement and IVC correction surgery, we observed a darker shade of red in the blood on the exit of the oxygenator. Laboratory tests demonstrated severe acidosis and hypoxemia. The ...
  http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0034-70942011000600010&lng=en&nrm=iso&tlng=en
*  Patent US5270005 - Extracorporeal blood oxygenation system incorporating integrated reservoir ... - Google Patents
An extracorporeal blood oxygenation system comprising an integral blood processing unit having a blood reservoir/oxygenator/heat exchanger/pump and pump motor and a remote control console connectable to the integral blood processing unit by way of non-blood containing connections such as electrical cable or the like.
  http://www.google.com.au/patents/US5270005
*  Patente US6129656 - Extracorporeal blood processing methods and apparatus - Google Patentes
An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which directs the operator through various aspects of the apheresis procedure. Moreover, the system also includes a variety of features relating to loading a blood processing vessel into a blood processing channel and removing the same after completion of the procedure. Furthermore, the system also includes a variety of features relating to utilizing a blood priming of at least portions of the apheresis system in preparation for the procedure. In addition, the system includes a variety of features enhancing the performance of the apheresis system, including the interrelationship between the blood processing vessel and the blood processing vessel and the utilization of high packing factors for the procedure.
  http://www.google.es/patents/US6129656?dq=flatulence
*  Correlation Between Access Blood Flow and Extracorporeal Blood Flow - Full Text View - ClinicalTrials.gov
Accesses that show a large (,15%) decrement over time in vascular access blood flow are associated with a high risk of thrombosis. Serial measurements of vascular access blood flow predict access thrombosis. At the moment, the measurement of access flow is time consuming, operator dependent, so that it cannot be done with every treatment. We hypothesized that extracorporeal blood flow at pressure of -200 to -260 mmHg in arterial line has correlation with access blood flow and this can be used to estimate access blood flow ...
  https://clinicaltrials.gov/ct2/show/NCT00522704?cond=%22Arteriovenous+Fistula%22&rank=8
*  Kit and method for converting water circulation system to water circulation and purification system - KING JOSEPH A.
A kit for converting a water circulation system in a hot tub into a water purification system including a housing that can be fixedly mounted to a spa or hot tub, a chamber in the housing, an inlet fo
  http://www.freepatentsonline.com/6328900.html
*  Patent US3661262 - Filtration and circulation system for maintaining water quality in ... - Google Patents
A filtration and circulation system for maintaining the water quality in a fish tank favorable for promoting the production and growth of fish therein and for circulating water therethrough at a rate designed to provide a high rate of water exchange in the tank. The system includes particulate, biological and activated charcoal filters serially arranged in pressurized and unpressurized sections thereof for converting or removing ammonia, waste food and excrement from the water. In addition, parallel flow paths from these filters through a protein skimmer and an ultraviolet sterilizer section, respectively, are provided for lower volume treatment of the water being circulated therethrough.
  http://www.google.co.uk/patents/US3661262
*  Extracorporeal circulation with low systemic heparinization during lung transplantation.
BACKGROUND: Some lung transplantation (LT) recipients suffer from pulmonary hypertension and right ventricular dysfunction or failure requiring extracorporeal circulation (ECC) to avoid catastrophic complications during surgery. The extracorporeal su
  http://www.biomedsearch.com/nih/Extracorporeal-circulation-with-low-systemic/16757296.html
*  Is it possible to block the cancer cells in circulating blood by extracorporeal circulation Implications of the immune system...
Is it possible to block the cancer cells in circulating blood by extracorporeal circulation Implications of the immune system and other factors review. . Download books free in pdf. Online library with books, university works and thousands of documents available to read online and download.
  http://books.duhnnae.com/2017/jun7/149820580875-Is-it-possible-to-block-the-cancer-cells-in-circulating-blood-by-extracorporeal-circulation-Implications-of-the-immune-system-and-other-factors-review.php
*  Pulsatile Flow Blood Pump
The invention is about a next-generation blood pump that provides pulsatile blood flow, and has been developed for cardiopulmonary by-pass devices used for maintaining extracorporeal blood circulation during heart surgeries and the supportive devices of circulation system. This device is technically a sort of synchronous power-assisted motor employing direct driver
  http://www.freshpatents.com/-dt20150521ptan20150141911.php
*  Cardiopulmonary Preserving Life (Zoll Lifebridge)
Apparatus and methods for providing extracorporeal blood circulation and oxygenation control include seven-stage de-airing of blood to provide automated cardiopulmonary replacement to sustain patient life during a medical procedure comprising repairing or replacing the heart valve in a patient.
  http://www.freshpatents.com/-dt20150521ptan20150141897.php
*  Extracorporeal Circulation | Cardiac Surgery in the Adult, 5e | AccessCardiology | McGraw-Hill Medical
Cardiopulmonary bypass (CPB) for support during cardiac surgery is unique because blood exposed to foreign, nonendothelial cell surfaces is collected and continuously recirculated throughout the body. This contact with synthetic surfaces within the perfusion circuit, as well as open tissue surfaces within the wound, triggers a defense reaction that involves at least five plasma protein systems and five types of circulating blood cells. This inflammatory response to CPB initiates a powerful thrombotic stimulus and the production, release, and circulation of vasoactive and cytotoxic substances that affect every organ and tissue within the body. Because of this, open-heart surgery (OHS) using CPB is essentially not possible without anticoagulation, usually with heparin; thus the inflammatory response to CPB involves the consequences of exposing heparinized blood to foreign surfaces, not lined with endothelial cells. ...
  http://accesscardiology.mhmedical.com/content.aspx?bookid=2157§ionid=164289346
*  Neurocognitive Outcome After Coronary Artery Bypass Surgery Using Minimal Versus Conventional Extracorporeal Circulation - Full...
Despite improvements in the biocompatibility of cardiopulmonary bypass (CPB) circuits, the activation of inflammatory systemic response can result in clinically relevant organ dysfunction. Regarding the central nervous system, prolonged hypoperfusion and microembolization during conventional CPB have been related to postoperative neurologic impairment with an incidence varying from 30% to 60%. This clinical scenario covers a spectrum from a transient subtle cognitive dysfunction to a permanent stroke. Postoperative cognitive decline (POCD) is characterized as impairment in attention, cognition, recognition, orientation, memory, and learning. It may result in prolonged hospitalization, increased morbidity and mortality, while it has an adverse impact on quality of life after surgery.. Near-infrared spectroscopy (NIRS) provides a continuous and noninvasive monitoring of regional cerebral oxygen saturation (rSO2). Recent studies have shown a significant relationship between intraoperative cerebral ...
  https://clinicaltrials.gov/ct2/show/NCT01213511?recr=Open&cond=%22Coronary+Artery+Bypass%22&rank=2
*  Scuba quiz: circulation system
B. False. Answers: Circulation. 1. A. True. The blood supply to the heart, efficiency of its muscle contractions, changes in rate and rhythm and increased work load all result from diving. Such stresses can be tolerated by a healthy heart, but can cause a heart attack in those with coronary problems. A person with any heart disorder should not dive unless cleared by both a cardiologist and a diving physician.. 2. B. False. The blood carries nearly as much oxygen as it can at all times. The change that takes place with exercise is in the circulation of the blood, which is increased to get oxygen to and waste products from tissues more quickly. Increased oxygen partial pressure while diving does allow more oxygen to be carried dissolved in the blood, but the benefit of this is offset by other cardiovascular changes.. 3. B. False. The carotid sinuses, located at the bifurcation of the arteries on each side of the neck, are sensors for blood pressure and provide information to ...
  http://spofitaholic.com/scuba-quiz-circulation-system/
*  Oral and Intravenous Iron in Patients Postoperative Cardiovascular Surgery Under Extracorporeal Circulation - Full Text View -...
Prospective double dummy triple blind study of 159 patients undergoing CPB; randomised in 3 groups treated with iron intravenously (iv) (group I), with iron orally (group II) controlled with placebo (group III). Patients from group I were treated with iv Iron sucrose , three doses of 100 mg of iv iron every 24 hours during postoperative hospitalization and 1 pill/24 h of oral placebo during the first month after discharge. Group II was programmed to receive 1 iron pill orally every 24 hours pre and postoperatively and up to one month after discharge and a placebo while hospitalized. Group III was programmed to receive an oral and iv placebo pre and postoperatively.. Variables were collected preoperatively, at operation room and at Intensive Care Unit admission and discharge, at postoperative floor discharge and at one month after surgical discharge. ...
  https://clinicaltrials.gov/show/NCT01078818
*  Extracorporeal Circulation in a Patient with Heparin-induced Thrombocytopenia | Anesthesiology | ASA Publications
We have emailed you at with instructions on how to set up a new password. If you do not receive an email in the next 24 hours, or if you misplace your new password, please contact:. ASA members: ...
  http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1955209
*  AmSECT : Blogs : Impact of minimally invasive extracorporeal circuits on octogenarians undergoing coronary artery bypass...
An Active Member shall be any perfusionist active in the practice of extracorporeal circulation technology. There are also opportunities to become a Transitional Active Member for those less than a year removed from graduation from an approved accredited training program. Other options include; an Associate Membership, International Membership, Perioperative Blood Management Clinician Membership, and Student Membership.. Click Here to Learn More ...
  http://www.amsect.org/blog/impact-of-minimally-invasive-extracorporeal-circuits-on-octogenarians-undergoing-coronary-artery-bypass-grafting.-have-we-been-looking-in-the-wrong-direction
*  Patente US5695717 - Gas exchange apparatus - Google Patentes
A gas exchange device (100) with an extracorporeal blood circuit (102) in which a blood pump (110) is connected, with a CO2 exchange unit (112), and an oxygenator (128), whereby the gas exchange unit (112, 128) is in each case divided by a hydrophilic, water-wet membrane (114, 130) into a blood chamber (116, 132) and a gassing chamber (118, 134) which is under positive transmembrane pressure.
  http://www.google.es/patents/US5695717?dq=flatulence
*  Patent US7896831 - Method and apparatus for calculating fluid flow rate - Google Patents
A switch valve for use in an extracorporeal blood flow circuit comprises a valve housing having a chamber, four openings communicating with the chamber, and a valve member located in the valve chamber. A first opening is to be connected to a patient via an arterial cannula, a second opening is to be connected to a patient via an venous cannula, a third opening is to be connected to a first inlet/outlet of a blood treatment device, and a fourth opening is to be connected to a second inlet/outlet of a blood treatment device. The valve member is movable within the valve housing to fluidly connect the first opening to either the third or the fourth opening and to fluidly connect the second opening to either the third or the fourth opening. The width of the valve member is smaller than a peripheral dimension of the openings.
  http://www.google.ca/patents/US7896831
*  Thermogard™ Efficacy Trial - Full Text View - ClinicalTrials.gov
Hypothermia in the severely burned has been shown to disrupt coagulation, impair myocardial function, weaken the host immune response, delay wound healing and increase mortality.. Current methods available for preventing and reversing hypothermia include administering heated, humidified oxygen, infusing warmed intravenous fluids centrally, performing peritoneal dialysis with warmed fluid, undergoing extracorporeal blood warming with partial bypass, and markedly increasing the ambient room temperature. These methods are either limited in their effectiveness or are impractical and potentially dangerous. Furthermore, the practice of markedly increasing the ambient room temperature creates a hostile work environment for health care providers which may impact patient care.. The FDA has classified the Alsius Thermogard™ heat exchange catheter as a Class II devices under 21 C.F.R §§ 870.5900. It is used in various clinical applications for cooling patients but it has not been ...
  https://clinicaltrials.gov/ct2/show/NCT00822796
*  Application # 2017/0071782. Apparatus and Method for Rapidly Cooling or Heating the Body Temperature of a Patient -...
An extracorporeal blood cooling or heating circuit includes an intravenous catheter for withdrawing a patient's blood coupled to a combined pump/heat exchanger device. One or more sensors are provide
  http://patents.com/us-20170071782.html
*  BBM/Aesculap AG
Aesculap AG (AAG): B. Braun is one of the world's leading suppliers of healthcare products. Its four divisions orient their products and services toward different medical fields: hospital, surgery, private practice (medical care and doctors' offices) and extracorporeal blood treatment. By networking the divisions' knowledge and developing solutions for the healthcare system, the company transforms products and services into integrated systems. B. Braun's Aesculap Division focuses on products and services for all of the core processes in surgery. Aesculap Division's headquarters are in Tuttlingen, Germany, where it has about 3,100 employees. Internationally, Aesculap has about 9,000 personnel, and production sites all over the world. Its product range includes surgical instruments for open or minimally invasive approaches, implants, surgical sutures, sterile container, storage, motor and navigation systems, as well as products for cardiology. Aesculap is the market leader in ...
  http://lifelongjoints.eu/bbmaesculap-ag/
*  Artificial Circulation and Its Role in Reanimation - Avinpharma.ru
From the beginning of the Thirties of the 20th century, right up to the present, many different designs for artificial circulation to be used both in experiments and in clinical practice, in cases of temporary arrest of cardiac circulation, have been described, es-pecially in connection with the use of such apparatus in cardio-vascular surgery. The expedience of using it in resuscitation however, was first suggested by Bryukhonenko and Chechulin. In order to determine the efficacy of artificial circulation in treating clinical death, Bryukhonenko devised his own perfusion apparatus, which he called an autojector.. Research carried out along these lines has confirmed the possibility of restoring respi-ration and cardiac activity by means of extracorporeal circulation in cases of clinical death due to loss of blood, drowning, asphyxia, explosive decom-pression, electric shock, and prolonged hypo-tension. It ...
  http://avinpharma.ru/en/clinical-pathophysiology/artificial-circulation-and-its-role-in-reanimation.html
*  Stony Brook University Graduate Bulletin - Spring 2013 - MEC
Building is treated as a time-dependent energy system, with its interactive components coupled through energy and mass flows under an environment defined in terms of sunlight, ambient air and wind and with its equipment which assist in meeting building-dwellers comfort requirements. Major components discussed are thermal mass (both interior mass and envelope mass) and their thermal capacities, building envelopes and their heat transfer resistances, room air including its circulation and heat exchange with thermal mass, and the transparent part of the envelope the glazing or windows and the solar system passing through it during the day and the heat loss during the night time. Major equipment include lighting, air circulation system, cooling and heating equipment, solar thermal panels and solar PV panels, and other equipment including integrated electric and control units. Of the comfort requirements only temperature-and-humidity and illumination are studied with the ...
  http://sb.cc.stonybrook.edu/gradbulletin/2013/spring/courses/mec/