*  Laboratory Primate Newsletter, Volume 41, Number 1
A modern human-like sequence of dental development is regarded as one of the diagnostic hallmarks of our own genus Homo. Brain ... the contribution of early alcohol exposure (juvenile and adolescent periods) to excessive drinking and abnormal cognitive and ... Gerald expresses an interest in welcoming new researchers and returning researchers to Cayo Santiago and is accepting proposals ... evaluation of the immediate and long-term consequences of heavy drinking during adolescence on cognitive/brain functioning; and ...
  http://www.brown.edu/Research/Primate/lpn41-1.html
*  Study reverses negative effects of adolescent marijuana use - UPI.com
Researchers at the University of Western Ontario developed a method to use pharmaceuticals to reverse the negative psychiatric ... Researchers found that the reduction of GABA as a result of THC exposure in adolescence caused the neurons in adulthood to be ... adolescent THC exposure modulates the activity of a neurotransmitter known as GABA in the prefrontal cortex region of the brain ... Chronic marijuana use during adolescence has been linked to the development of psychiatric diseases such as schizophrenia in ...
  https://www.upi.com/Health_News/2017/09/12/Study-reverses-negative-effects-of-adolescent-marijuana-use/2121505228163/?utm_source=upi&utm_campaign=mp&utm_medium=2
*  Study reveals neurobehavioral impact of chronic alcohol-vapor exposure during adolescence
The developmental period from adolescence to adulthood is accompanied by a greater vulnerability to addictions - including ... NIH releases unparalleled dataset from Adolescent Brain Cognitive Development study. *New device could allow people with ... Researchers conducted two parallel tests in adult male mice following their exposure to alcohol vapors during adolescence (4-6 ... Study reveals neurobehavioral impact of chronic alcohol-vapor exposure during adolescence. *Download PDF Copy ...
  https://www.news-medical.net/news/20170615/Study-reveals-neurobehavioral-impact-of-chronic-alcohol-vapor-exposure-during-adolescence.aspx
*  Schizophrenia
Childhood and adolescent development. Schizophrenia is most commonly first diagnosed during late adolescence or early adulthood ... currently most researchers and clinicians believe it results from a combination of both brain vulnerabilities (either inherited ... prenatal exposure to infections increases the risk for developing schizophrenia later in life, providing additional evidence ... Perinatal brain development. It is thought that causal factors can initially come together in early neurodevelopment, including ...
  http://www.cs.mcgill.ca/~rwest/wikispeedia/wpcd/wp/s/Schizophrenia.htm
*  Binge drinking - Wikipedia
Alcohol affects brain development quite significantly especially during adolescence when the brain is still developing. The ... "Adolescent ethanol exposure: does it produce long-lasting electrophysiological effects?". Alcohol. 44 (1): 27-37. doi:10.1016/j ... While several rat studies indicate that alcohol is more toxic during adolescence than adulthood, some researchers believe that ... Though heavy binge drinking adolescent humans show impaired brain activity during memory tests and underdeveloped brain ...
  https://en.wikipedia.org/wiki/Binge_drink
*  Researchers reverse the negative effects of adolescent marijuana use
Researchers at Western University have found a way to use pharmaceuticals to reverse the negative psychiatric effects of THC, ... as a result of THC exposure in adolescence caused the neurons in adulthood to not only be hyperactive in this part of the brain ... Chronic adolescent marijuana use has previously been linked to the development of psychiatric diseases, such as schizophrenia, ... In a study published online today in Scientific Reports the researchers demonstrate that adolescent THC exposure modulates the ...
  https://medicalxpress.com/news/2017-09-reverse-negative-effects-adolescent-marijuana.html?utm_source=tabs&utm_medium=link&utm_campaign=story-tabs
*  Fetal alcohol exposure affects teenage drinking behavior
... an important relationship between fetal and adolescent experiences that appears essential to the progressive development of ... The researchers state that a fetus can recall and be drawn to odor stimuli from what its mother ingests during pregnancy. ... They believed that being exposed to alcohol in the womb trains the brain to make the smell of liquor more appealing. Although ... This is crucial because adolescence is the turning point when behavior patterns take shape and any most of the addictions begin ...
  http://treatmentcenters.com/alcohol-addiction/fetal-alcohol-exposure-affects-teenage-drinking-behavior/
*  Marijuana's Lasting Effects on the Brain | National Institute on Drug Abuse (NIDA)
They have shown that exposure to cannabinoids during adolescent development can cause long-lasting changes in the brain's ... The new research is part of a large-scale study of health and development conducted in New Zealand. Researchers administered IQ ... This finding is consistent with the notion that drug use during adolescence-when the brain is still rewiring, pruning, and ... A recent report in Brain, for example, reveals neural-connectivity impairment in some brain regions following prolonged ...
  https://www.drugabuse.gov/about-nida/directors-page/messages-director/2012/09/marijuanas-lasting-effects-brain
*  Study of plastics' impact on human development receives 5-year, $8 million grant
... impact on human development receives 5-year, $8 million grant -- a press release is provided to you ìas isî with little or no ... Their exposure to the compounds of interest is being measured through urine samples collected during the adolescent period. The ... Researchers hypothesize that oxidative stress in the gonads and the brain leads to permanent deficits in reproductive and ... interact with diets high in saturated fat to impact neurological and reproductive function prenatally and during adolescence- ...
  https://phys.org/wire-news/138021149/study-of-plastics-impact-on-human-development-receives-5-year-8.html
*  FIU takes an interdisciplinary approach to neuroscience research
The brain is the most complex organ in the human body. It makes up two percent of a body's mass yet uses 20 percent of its ... is part of a research team working on the multi-year national landmark study on substance use and adolescent brain development ... "brain signatures," or unique patterns of brain activity. An understanding of such signatures could one day help researchers ... He uses behavioral, cellular and molecular approaches to reveal the effects of heavy metal exposure on the developing brain, ...
  https://news.fiu.edu/2016/05/fiu-takes-an-interdisciplinary-approach-to-neuroscience-research/100063
*  Binge drinking - Wikipedia
Alcohol affects brain development quite significantly especially during adolescence when the brain is still developing. The ... An adolescent rat study found that a relatively short exposure to high levels of alcohol resulted in long-lasting changes to ... While several rat studies indicate that alcohol is more toxic during adolescence than adulthood, some researchers believe that ... Though heavy binge drinking adolescent humans show impaired brain activity during memory tests and underdeveloped brain ...
  https://en.wikipedia.org/wiki/Binge_drinking
*  High-fat diet in pregnancy can cause mental health problems in offspring
... but new research in an animal model suggests it alters the development of the brain and endocrine system of their offspring and ... finding that exposure to a high-fat diet during gestation and early in development impaired the development of neurons ... Exposure to a high-fat diet in the womb and after birth can permanently change the cells in the brain that control food intake ... what is eaten during adolescence or childhood development may alter long-term behavior and learning, and can even ... ...
  https://medicalxpress.com/news/2017-07-high-fat-diet-pregnancy-mental-health.html
*  Repeated Adolescent 3,4-Methylenedioxymethamphetamine (MDMA) Exposure in Rats Attenuates the Effects of a Subsequent Challenge...
The development of tolerance occurred in the absence of substantial serotonergic neurotoxicity (from the adolescent exposure) ... Furthermore, adolescent MDMA impaired the behavioral response to a 5-HT1A/7 agonist. Future researchers should further ... Spear LP (2000) The adolescent brain and age-related behavioral manifestations. Neurosci Biobehav Rev 24: 417-463. ... The major finding of the first experiment was that intermittent exposure to MDMA during adolescence profoundly attenuated or ...
  http://jpet.aspetjournals.org/content/317/2/838
*  Longitudinal Examination of Learning and Memory in Rats Following Adolescent Exposure to 3,4-Methylenedioxymethamphetamine or 5...
The protocol involved repeated doses of either MDMA or Foxy during the period defined as mid-adolescence (postnatal days 34 - ... no significant group differences in serotonin or dopamine levels were found in any of the measured regions of the brain changes ... Here we investigated whether the reported effects following adolescent exposure resolved in early adulthood or continued ... of the present research was to explore the effects of MDMA or Foxy on cognitive processes associated with adolescent exposure ...
  http://www.scirp.org/journal/PaperInformation.aspx?PaperID=78972
*  Adolescent Binge Drinking Impairs Cognitive and Behavioral Control - Jim Liebelt Christian Blog
... and commentary on Crosswalk.com ... it is possible that alcohol exposure might alter the course of brain development. Rodent models used in this study are ... In a final experiment, the researchers found that heavy adolescent alcohol drinking, but not sweetened water, predicted poor ... Binge drinking can have lasting effects on brain pathways that are still developing during adolescence, say neuroscience ...
  https://www.crosswalk.com/blogs/liebelt/adolescent-binge-drinking-impairs-cognitive-and-behavioral-control.html
*  NIAAA Director's Report on Institute Activities to The 119th Meeting of the National Advisory Council on Alcohol Abuse and...
NIAAA is interested in the effects of alcohol exposure during the preadolescent and adolescent stages on brain development. To ... from early adolescence through middle adulthood in a retrospective study of adult twin pairs. The researchers recorded levels ... Antonio Noronha co-chaired a symposium on "Adolescent Brain Development: Ethanol Induced Cellular and Molecular Changes" ... They found that the amount of a specific microRNA molecule known as miR-9 increases in brain cells within minutes of exposure ...
  https://www.niaaa.nih.gov/about-niaaa/our-work/advisory-council/directors-reports-council/niaaa-directors-report-institute-119
*  PA-18-653: Developmentally Tailored HIV Prevention and Care Research for Adolescents and Young Adults (R34 Clinical Trial...
... that brain development was relatively complete prior to adolescence, recent research has demonstrated that adolescence is a ... HIV and/or exposure at critical time points to HIV on the developing adolescent brain ... Are the PD(s)/PI(s), collaborators, and other researchers well suited to the project? If Early Stage Investigators or those in ... of inflammation from the persistent exposure to HIV in the CNS could have a more substantial impact on brain development during ...
  https://grants.nih.gov/grants/guide/pa-files/PA-18-653.html
*  Teens and Cannabis Use - Social Work Today Magazine
"Adolescence is a period of intense brain development, involving a pruning of neurons in certain areas and myelination of other ... The sentiment is shared by Gaya Dowling, PhD, director of the Adolescent Brain Cognitive Development (ABCD) Study at the ... Exposure to substances during this period could therefore have long-lasting (perhaps permanent) effects on how the brain ... the ABCD researchers are more likely to have the ability to document the difference in a youth's development prior to and after ...
  http://www.socialworktoday.com/archive/ND17p5.shtml
*  Landmark National Study of Adolescent Brain Now Underway
Yet researchers know comparatively little about the teenage brain. The Adolescent Brain Cognitive Development (ABCD) study - by ... we will be able to learn how a variety of biological events and environmental exposures affect brain development, giving us ... If you've lived through your own or your kids' adolescence, you know it's an extraordinary time, marked by tremendous growth ... The largest long-term study of brain development and child health in the United States, the landmark research project will ...
  http://ucsdnews.ucsd.edu/pressrelease/landmark_national_study_of_adolescent_brain_now_underway
*  Patterns of cannabis use during adolescence and their association with harmful substance use behaviour: findings from a UK...
3 The potential harms of cannabis use during adolescence include altered brain development, cognitive impairment, chronic ... to test the relationship between adolescent exposure and outcomes in adulthood, it is important that the trajectories are ... www.bristol.ac.uk/alspac/researchers/dataaccess/) describes in detail the policy regarding data sharing which is through a ... In part, this is because of a lack of longitudinal studies and refined measures of cannabis exposure during adolescence. ...
  http://jech.bmj.com/content/71/8/764
*  Cannabis use likely to affect teen brains - Healthcanal.com : Healthcanal.com
"During adolescence the endocannabinoid system in the brain undergoes a lot of change, and interfering with these changes by ... Researchers Examine How Opioids Affect Proteins in the Brain Other than Opioid Receptors ... "Disrupting endocannabinoid signalling through exposure to cannabis is likely to have a higher impact if the exposure happens at ... adolescent brain may be more vulnerable to the effects of cannabis is significant," says Dr Long. ...
  https://www.healthcanal.com/substance-abuse/32844-cannabis-use-likely-to-affect-teen-brains.html
*  TSRI - News & Views
Adolescence is a time when drugs are very toxic, not unlike fetal development,' she says. 'The brain is going through its final ... She also found adolescent exposure to nicotine also has life-long effects on rodent brain function. ... The researchers examined how consumption of precise amounts of alcohol affected blood pressure, heart rate, brain waves, and ... level of development, a process called brain pruning, where all the connections between the brain's neurons start reducing to ...
  http://www.scripps.edu/newsandviews/e_20070813/ehlers.html
*  The identification of risk for serious mental illnesses: Clinical and ethical challenges | NeuroEthicsWomen Leaders
Her research is focused on child and adolescent development and the brain changes that are associated with adolescence. ... and the principle of doing no harm guides practitioners and clinical researchers. Furthermore, clinical researchers emphasize ... The first is to reduce morbidity by reducing risk exposure. The second is to enhance opportunities for targeting preventive ... The brain is generally assumed to be the organ that subserves our mind and personal identity, and the behavioral problems that ...
  https://neuroethicswomenleaders.com/2013/05/31/the-identification-of-risk-for-serious-mental-illnesses-clinical-and-ethical-challenges/
*  Fight Aging! Newsletter, March 11th 2013 - Fight Aging!
When researchers blocked the function of this gene in old mice, they reset the old brain to adolescent levels of plasticity. " ... "These are the molecules the brain needs for the transition from adolescence to adulthood. It suggests we can turn back the ... The development of such reagents is an indispensible enabling technology for the development and testing of candidate ... Sexual experience enhanced the number of newly generated neurons in the dentate gyrus with both single and repeated exposures ...
  https://www.fightaging.org/archives/2013/03/fight-aging-newsletter-march-11th-2013/
*  Cantabrians in large study on impact of teenage cannabis use - Healthcanal.com : Healthcanal.com
Researchers Examine How Opioids Affect Proteins in the Brain Other than Opioid Receptors ... and the likely adverse effects on adolescent development, Professor Fergusson says. The New Zealand part of the study was ... He says the findings reinforce the message that cannabis use in adolescence, and particularly early onset regular cannabis use ... Children's Exposure to Secondhand Smoke May Be Vastly Underestimated by Parents 11/10/2017 Substance Abuse ...
  https://www.healthcanal.com/substance-abuse/54995-cantabrians-in-large-study-on-impact-of-teenage-cannabis-use.html