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*  Alphavirus - Wikipedia
Alphaviruses are of interest to gene therapy researchers, in particular the Ross River virus, Sindbis virus, Semliki Forest ... which is structurally different from the class I fusion proteins found in influenza virus and HIV. The structure of the Semliki ... Upon exposure of the virus to the acidity of the endosome, E1 dissociates from E2 to form an E1 homotrimer, which is necessary ... virus O'nyong-nyong virus Pixuna virus Rio Negro virus Ross River virus Salmon pancreas disease virus Semliki Forest virus ...
  https://en.wikipedia.org/wiki/Alphavirus
*  Structure of the Lassa virus glycan shield provides a model for immunological resistance | PNAS
S1C). These isomers have also been observed in HIV-1 (gp120) and Semliki Forest virus E1 and E2 glycoproteins (41, 42); it is ... 2010) Cross-neutralization of 1918 and 2009 influenza viruses: Role of glycans in viral evolution and vaccine design. Sci ... it has often been observed on enveloped viruses, such as orthomyxoviruses, phleboviruses, alphaviruses, and flaviviruses (56). ... which requires pH-dependent conformational rearrangements of the GPC spike upon exposure to the late endosomes. Indeed, ...
  http://www.pnas.org/content/early/2018/06/19/1803990115
*  Bluetongue Virus
... this book serves as an invaluable resource for researchers and clinicians working with alphaviruses and related viruses. Topics ... As the first to focus exclusively on alphaviruses, ... Influenza: Current Research. *Virus Evolution: Current Research ... Thus, a plausible hypothesis would be that the attachment of VP2 with receptor and subsequent low pH inside endosomes induce a ... Recommended: Genes, Genetics and Transgenics for Virus Resistance in Plants Bluetongue Virus. Porcine Viruses: From ...
  https://www.highveld.com/virology/bluetongue-virus.html
*  A Single Point Mutation Controls the Cholesterol Dependence of Semliki Forest Virus Entry and Exit | JCB
In vitro and/or in vivo studies of influenza virus, a myxovirus, and vesicular stomatitis virus, a rhabdovirus, suggest that ... and low pH-triggered fusion of the virus membrane with that of the endosome. Virus membrane fusion is carried out by the 80 ... SFV is a member of the alphaviruses, enveloped positive- stranded RNA viruses with highly ordered icosahedral structures in ... Semliki Forest virus); RRV (Ross River virus); ONN (O'Nyong-nyong virus); CHIK (Chikungunya virus) (NCBI 576465); EEE (Eastern ...
  http://jcb.rupress.org/content/140/1/91
*  Chikungunya - Wikipedia
It is a member of the Semliki Forest virus complex and is closely related to Ross River virus, O'nyong'nyong virus, and Semliki ... E1 contains a fusion peptide which, when exposed to the acidity of the endosome in eukaryotic cells, dissociates from E2 and ... and infection with influenza. Chronic recurrent polyarthralgia occurs in at least 20% of chikungunya patients one year after ... "Evolutionary relationships and systematics of the alphaviruses". Journal of Virology. 75 (21): 10118-31. doi:10.1128/JVI.75.21. ...
  https://en.wikipedia.org/wiki/Chikungunya
*  The Briarfield Chronicles: May 2012
... and dengue viruses, and on alphaviruses, such as Semliki Forest and Sindbis viruses. ... Figure 3 - Influenza virus hemagglutinin: proposed sequence of fusogenic conformational changes.. Activating and initiating. * ... a, E binds to a receptor on the cell surface and the virion is internalized to an endosome. b, Reduced pH in the endosome ... Influenza virus hemagglutinin. *Core of HA1 is a sialic acid-binding domain borne on stalk formed by HA2 ...
  http://thebriarfieldchronicles.blogspot.com/2012_05_01_archive.html
*  Elucidation of antigenic epitopes on the rubella virus E1 glycoprotein - UBC Library Open Collections
Semliki Forest virus, Sindbis virus and Rubella virus. J. Gen. Virol 46:467-475.Vaheri, A. and Hovi, T. (1972) Structural ... In hepatitisB virus and influenza virus, cytotoxic T cell sites that are crucial for viral clearance havebeen mapped to non- ... The RV non-structural proteins are yet to bedefined and analyzed but are thought to be similar to those of alphaviruses.0^1.0^ ... The vesicles fuse with endosomes resultingin acidification of the vesicles. This causes a conformational change in the ...
  https://open.library.ubc.ca/cIRcle/collections/ubctheses/831/items/1.0098839
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
Semliki Forest virus vectors expressing IL-12 (SFV-IL-12) were shown to induce potent antitumor responses against s.c. MC38 ... Both types of endosomes elicited LLO(90-91)/CD8(+) and LLO(189-201)/CD4(+) specific immune responses. However, only endosomes ... Alphaviruses contain a single-strand RNA genome that can be modified to express heterologous genes at high levels. Alphavirus ... Influenza, but not HIV-specific CTL epitopes, elicits delayed-type hypersensitivity (DTH) reactions in HIV-infected patients. ...
  https://www.jove.com/visualize?author=Marta%20Ruiz-Ortega%20
*  CYCLIC AMP PHOSPHODIESTERASE 4D7 ISOFORMS AND METHODS OF USE - Memory Pharmaceuticals Corporation
Sindbis virus vectors, Semliki forest virus (ATCC VR-67; ATCC VR-1247), Ross River virus (ATCC VR-373; ATCC VR-1246) and ... The HA tag corresponds to an epitope derived from the influenza hemagglutinin protein (Wilson, I., et al., Cell, 37:767 (1984 ... Such vectors can be constructed from a wide variety of alphaviruses, including, for example, ... may be improved further by treatment of the beads to increase hydrophobicity and thereby facilitate disruption of the endosome ...
  http://www.freepatentsonline.com/y2005/0289660.html
*  Cytopathic Mechanisms of HIV-1 | Virology Journal | Full Text
With relatively few proteins made by the virus, it is able to accomplish many tasks, with each protein serving multiple ... The human immunodeficiency virus type 1 (HIV-1) has been intensely investigated since its discovery in 1983 as the cause of ... Nieva JL, Sanz MA, Carrasco L: Membrane-permeabilizing motif in Semliki forest virus E1 glycoprotein. FEBS Lett 2004, 576: 417- ... Influenza virus. The prototype viroporin, M2 protein, was first isolated from the influenza A virus. M2 protein is one of three ...
  https://virologyj.biomedcentral.com/articles/10.1186/1743-422X-4-100