*  The Biological Activity of AZD2171 in GIST
... clinicaltrials.gov To determine the anti-tumour activity and biological effects of AZD2171 at a dose of 45mg, primarily in GIST ... Sex Cord-gonadal Stromal Tumors. Neoplasms derived from the primitive sex cord or gonadal stromal cells of the embryonic GONADS ... Endometrial Stromal Tumors. Neoplasms of the endometrial stroma that sometimes involve the MYOMETRIUM. These tumors contain ... From the sex cord, there are SERTOLI CELL TUMOR and GRANULOSA CELL TUMOR; from the gonadal stroma, LEYDIG CELL TUMOR and ...
  https://www.bioportfolio.com/resources/trial/104435/The-Biological-Activity-of-AZD2171-in-GIST.html
*  Uterine tumour resembling ovarian sex cord tumour is an immunohistochemically polyphenotypic neoplasm which exhibits...
... type I were typical endometrial stromal neoplasms with focal areas with a sex cord‐like pattern; in type II tumours, the sex ... An origin from displaced gonadal sex cord cells is also a possibility but EMA positivity is against this theory. As discussed, ... and CD99 expression in sex cordstromal tumors and endometrioid ovarian carcinomas resembling sex cordstromal tumors. Hum ... Uterine tumour resembling ovarian sex cord tumour exhibiting positivity with sex cord markers α inhibin (A), calretinin (B), ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2014850/
*  Ovarian cancer - Wikipedia
... they can cause or occur at the same time as endometrial cancer or breast cancer. Other sex-cord/stromal tumors present with ... a mutation known for its role in gastrointestinal stromal tumor. People with an XY karyotype and ovaries (gonadal dysgenesis) ... Symptoms of sex cord-stromal tumors produce hormones that can affect the development of secondary sex characteristics. Sex cord ... Granulosa cell tumors are the most common sex-cord stromal tumors, making up 70% of cases, and are divided into two histologic ...
  https://en.wikipedia.org/wiki/Ovarian_cancer
*  Extraovarian Granulosa Cell Tumor of Mesentery: A Case Report
Granulosa cell tumors (GCT) are the malignant sex cord-stromal tumors of the ovary. They constitute 1-2% of all ovarian tumors ... Extraovarian granulosa cell tumor (GCT) is a very uncommon tumor, assumed to arise from the ectopic gonadal tissue along the ... endometrial stromal sarcoma, carcinoid, and lymphoma [1]. These tumors do not show positivity for inhibin. IHC for CK, EMA, LCA ... Granulosa cell tumors (GCT) are the most common malignant sex cord-stromal tumors of the ovary [1]. They can arise in locations ...
  https://www.hindawi.com/journals/pri/2010/292606/
*  Primary Retroperitoneal Extraovarian Granulosa Cell Tumor: A Case Report
... the ectopic gonadal stromal tissue is believed to be responsible for the histogenesis of extraovarian sex-cord stromal tumors [ ... endometrial stromal sarcoma, carcinoid, malignant melanoma, intraabdominal desmoplastic small-cell tumor) [7]. The use of a ... Gross and microscopic features failed to differentiate between carcinoid tumor and sex-cord stromal tumor of granulosa cell ... The influence of mesonephros in the origin of the sex cord explains why the sites of extraovarian sex-cord stomal tumors are ...
  https://www.urotoday.com/volume-3-2010/vol-3-issue-6/40013-primary-retroperitoneal-extraovarian-granulosa-cell-tumor-a-case-report-2232933.html
*  List of MeSH codes (C04) - Wikipedia
... sex cord-gonadal stromal tumors MeSH C04.557.475.750.656 --- granulosa cell tumor MeSH C04.557.475.750.751 --- luteoma MeSH ... endometrial stromal tumors MeSH C04.588.945.418.948.585.374.500 --- sarcoma, endometrial stromal MeSH C04.588.945.418.948.850 ... rhabdoid tumor MeSH C04.557.435.775 --- sarcoma, endometrial stromal MeSH C04.557.435.850 --- thymoma MeSH C04.557.450.550 --- ... mixed tumor, malignant MeSH C04.557.435.530 --- mixed tumor, mesodermal MeSH C04.557.435.540 --- mixed tumor, mullerian MeSH ...
  https://en.wikipedia.org/wiki/List_of_MeSH_codes_(C04)
*  Paediatric ovarian tumours and their associated cancer susceptibility syndromes | Journal of Medical Genetics
SEX CORD-STROMAL TUMOURS (SCST). Juvenile granulosa cell tumour. General aspects. Juvenile granulosa cell tumours (JGCTs) ( ... Gonadal tumor in Frasier syndrome: a review and classification. Cancer Prev Res 2015;8:271-6.doi:10.1158/1940-6207.CAPR-14-0415 ... The differential diagnosis may include a wide range of neoplasms, including AGCT, JGCT, germ cell tumours, endometrial stromal ... Sex cord-stromal tumors of the ovary and testis: their similarities and differences with consideration of selected problems. ...
  http://jmg.bmj.com/content/55/1/1
*  XIX - Female Genital System and the Breast Flashcards by Ian Argel | Brainscape
Biomarker useful for identifying granulosa an other sex cord-stromal tumors, and monitoring treatment. ... cystically dilated endometrial glands, with single layer of endometrial cells (B) crowded branched endometrial glands, with ... Which of the following tumors is most responsive to chemotherapy? (A) gonadal choriocarcinoma (B) gestational choriocarcinoma ( ... Sex cord tumor seen as small, gray to yellow-brown, and solid lesions. May resemble development of testis with tubules, or ...
  https://www.brainscape.com/flashcards/xix-female-genital-system-and-the-breast-3863496/packs/5709922
*  J K Chan
sex cord gonadal stromal tumors*neoplasm staging*glandular and epithelial neoplasms*seer program*papillary carcinoma*sarcoma* ... endometrial neoplasms*survival analysis*germ cell and embryonal neoplasms*uterine hemorrhage*proportional hazards models* ... Prognostic factors responsible for survival in sex cord stromal tumors of the ovary--an analysis of 376 women. Mallory Zhang. ... Prognostic factors responsible for survival in sex cord stromal tumors of the ovary--a multivariate analysis. John K Chan. ...
  https://www.labome.org/expert/usa/stanford/chan/j-k-chan-211225.html
*  Global Library of Women's Medicine - Benign Neoplasms of the Ovary, Fallopian Tube, and Parovarian Region - DOI 10.3843/GLOWM...
The sex cord stromal tumors (i.e., granulosa cell tumors and Sertoli-Leydig cell tumors) occur in both benign and malignant ... Bleeding and endometrial hyperplasia may be the problem that brings a patient to a physician, and endometrial cancer has been ... Witschi E: Migration of the germ cells of human embryos from the yolk sac to the primitive gonadal folds. Contrib Embryol 32: ... Roth LM: Sex cord-stromal and lipid cell tumors of the ovary. In Fox H (ed): Haines and Taylor Obstetrical and Gynecological ...
  http://editorial.glowm.com/?p=glowm.cml/section_view&articleid=8
*  Books by Subject - Lane Medical Library - Stanford University School of Medicine
Germ Cell and Sex Cord Stromal Tumors: Clinical Introduction -- Pathology of Germ Cell Tumors -- Sex Cord Stromal Tumors of the ... Endometrial epithelial neoplasms -- Nonepithelial tumors of uterine corpus -- Gestational trophoblastic disease -- Tumors of ... Gonadal dysgenesis: ovarian function and reproductive health in Turner syndrome / Paul Saenger and David Rodriguez-Buritica -- ... Malignant germ cell tumors and sex cord stromal tumors in adults and children / Jubilee Brown and David M. Gershenson -- 29. ...
  http://lane.stanford.edu/biomed-resources/ebsubjectbrowse.html?m=Obstetrics%20and%20Gynecology&proxy-links=true
*  WNT4 - Wikipedia
XY Complete Gonadal Dysgenesis OMIM entries on 46,XY Disorder of Sex Development and 46,XY Complete Gonadal Dysgenesis This ... For example, it regulates endometrial stromal cell proliferation, survival, and differentiation. These processes are all ... Moreover, there is delay in sex cord formation. These issues are usually compensated for at birth. WNT4 also interacts with ... "WNT-4 mRNA expression in human adrenocortical tumors and cultured adrenal cells". Hormone and Metabolic Research = Hormon- Und ...
  https://en.wikipedia.org/wiki/WNT4
*  Endocrine Immune Interactions in the Host-Parasite Relationship: Steroid Hormones as Immune Regulators in Parasite Infections ...
Additionally, E2 inhibits MCP-1 expression in endometrial stromal cells by controlling endometrial macrophage migration [57]. ... Pregnancy and tumor. Am J Reprod Immunol 64: 77-86.. *Klein SL (2004) Hormonal and immunological mechanisms mediating sex ... 2006) Involvement of gonadal steroids and gamma interferon in sex differences in response to blood-stage malaria infection. ... 2008) Effect of 17beta-estradiol on signal transduction pathways and secondary damage in experimental spinal cord trauma. Shock ...
  https://www.omicsonline.org/open-access/endocrine-immune-interactions-in-the-hostparasite-relationship-steroidhormones-as-immune-regulators-in-parasite-infections-2157-7536-1000165.php?aid=66321
*  Protocols and Video Articles Authored by Richard Kline (Translated to Norwegian)
The more common sex cord-stromal tumors include granulosa stromal cell tumors, Sertoli-Leydig cell tumors, and ... Phase III Trial of Doxorubicin Plus Cisplatin with or Without Paclitaxel Plus Filgrastim in Advanced Endometrial Carcinoma: a ... female and intersex fish collected from oil platforms were determined in conjunction with gonadal histology. Rock hind social ... and sex cord-stromal tumors. Nonneoplastic conditions of the ovary that may present as adnexal masses include the following, ...
  https://www.jove.com/author/Richard_Kline?language=Norwegian
*  Long-Term Effects of Bone Marrow Transplantation: Overview, Immunosuppression and Graft Versus Host Disease After Hematopoietic...
Double-Blind Controlled Study of Efficacy and Safety of Umbilical Cord-Derived Mesenchymal Stromal Cells in the Prophylaxis of ... Clinically assess gonadal function in postpubertal female patients on an annual basis and within 1 year of transplant in ... The known risks of estrogen (ie, predisposition to endometrial and breast cancer [77] ) must be weighed against the risks of ... The above cited study of children with leukemia found that although the risk of solid tumors increased with time, the risk of ...
  https://emedicine.medscape.com/article/989518-overview
*  Nelson Teng | Stanford Medicine Profiles
... germ cell tumors, sex cord stromal tumors, and sarcomas. Moreover, the extent of lymphadenectomy (0 nodes, less than 10 nodes, ... The common epithelial tumors of the human ovary have rarely been found in the gonads of intersex patients with gonadal ... Lymphangioleiomyomatosis of the uterus simulating high-stage endometrial stromal sarcoma GYNECOLOGIC ONCOLOGY Longacre, T. A., ... of the ovary have been well characterized and include primitive germ cell tumor, sex cord stromal tumor, and metastasis. ...
  https://med.stanford.edu/profiles/nelson-teng
*  International Classification of Diseases for Oncology - Wikipedia
NOS Sex cord/gonadal stromal tumor, NOS Testicular/ovarian stromal tumor M8591/1 Sex cord-gonadal stromal tumor, incompletely ... NOS Endometrial sarcoma, NOS Endometrial stromal sarcoma, high grade M8931/3 Endometrial stromal sarcoma, low grade ... differentiated M8592/1 Sex cord-gonadal stromal tumor, mixed forms M8593/1 Stromal tumor with minor sex cord elements M8600/0 ... benign M9835/1 Stromal tumor, NOS M8935/3 Stromal sarcoma, NOS M8936/0 Gastrointestinal stromal tumor, benign GIST, benign ...
  https://en.wikipedia.org/wiki/International_Classification_of_Diseases_for_Oncology
*  The WikiDoc Living Textbook of Oncology - wikidoc
Gonadal (8590-8679). Sex cord-stromal tumour: Thecoma - Granulosa cell tumour - Luteoma - Sertoli-Leydig cell tumour ... Endodermal sinus tumor. Endometrial cancer. Endometrial hyperplasia. Endometrial intraepithelial neoplasia. Enteropathy- ... Gastrointestinal stromal tumor. Gemistocytic astrocytoma. Germ cell tumor. Germinoma. Gestational trophoblastic neoplasia. ... Carcinoid tumor of the lung. Carcinoma of the penis. Cardiac tumors. Carotid body tumor. Cementoblastoma. Cervical cancer. ...
  https://www.wikidoc.org/index.php/The_WikiDoc_Living_Textbook_of_Oncology
*  Shopping Page. Buy or upgrade website. - Healthmatics | Page 18
A sex cord-stromal tumor occurring in the testis and rarely in the ovary. It is predominantly or completely composed of Leydig ... Gonadal interstitial or stromal cell neoplasm composed of only LEYDIG CELLS. These tumors may produce one or more of the ... The oral contraceptive prevents pregnancy by preventing ovulation and by inducing endometrial and cervical changes undesirable ... Sera from tumor-bearing patients block the LAI reaction of their own leukocytes or those of other patients with the same type ...
  http://healthmatics.info/products-page/18/
*  Ovarian germ cell cancer | definition of Ovarian germ cell cancer by Medical dictionary
... germ cell tumors, and gonadal stromal (sex cord) tumors. Primary epithelial tumors comprise approximately 90% of all ovarian ... Tests are available which can help to determine whether a woman who has a family history of breast, endometrial, or ovarian ... include endodermal sinus malignant tumors, embryonal carcinoma, immature teratomas, and dysgerminoma. Sex cord tumors, which ... Germ cell tumors develop in the egg-producing cells of the ovary, and comprise about 5% of ovarian tumors. These tumors are ...
  https://medical-dictionary.thefreedictionary.com/Ovarian+germ+cell+cancer
*  Brenner tumour - WOW.com
Sex cord-gonadal stromal. *Leydig cell tumour. *Sertoli cell tumour. *Sertoli-Leydig cell tumour ... Endometrioid tumor. *Uterine papillary serous carcinoma. *Clear cell carcinoma. *Endometrial intraepithelial neoplasia ... Brenner tumors are an uncommon subtype of the surface epithelial-stromal tumor group of ovarian neoplasms. The majority are ... without the characteristic stromal/epithelial pattern of a Brenner tumour.. Eponym. It is named for Fritz Brenner (1877-1969), ...
  http://www.wow.com/wiki/Brenner_tumour?s_pt=aolsem&s_chn=9
*  Cystic, mucinous, and serous neoplasms - WOW.com
Sex cord-gonadal stromal. *Leydig cell tumour. *Sertoli cell tumour. *Sertoli-Leydig cell tumour ... Endometrioid tumor. *Uterine papillary serous carcinoma. *Clear cell carcinoma. *Endometrial intraepithelial neoplasia ... Tumors: female urogenital neoplasia (C51-C58/D25-D28, 179-184/218-221) ...
  http://www.wow.com/wiki/Cystic,_mucinous,_and_serous_neoplasms?s_pt=aolsem&s_chn=9
*  Dysgerminoma - WOW.com
Sex cord-gonadal stromal. *Leydig cell tumour. *Sertoli cell tumour. *Sertoli-Leydig cell tumour ... Endometrioid tumor. *Uterine papillary serous carcinoma. *Clear cell carcinoma. *Endometrial intraepithelial neoplasia ... A tumor of the identical histology but not occurring in the ovary may be described by an alternate name: seminoma in the testis ... A dysgerminoma is a type of germ cell tumor;[1] it usually is malignant and usually occurs in the ovary. ...
  http://www.wow.com/wiki/Dysgerminoma?s_pt=aolsem&s_chn=9
*  FOXL2 gene | Cancer Genetics Web
Sex Cord-Gonadal Stromal Tumors. *Childhood Cancer. *Up-Regulation. *Single Nucleotide Polymorphism ... A total of 546 tumours (205 cervical, 227 endometrial, 89 ovarian, and 25 vulvar carcinomas) were used to test and validate our ... Here we demonstrate that factors elaborated by malignant stromal cells can induce Luminal tumor cells proliferation and promote ... Moreover since BRCA1 tumors and sporadic triple negative (TN) breast tumors share similarities regarding clinical outcomes and ...
  http://www.cancerindex.org/geneweb/FOXL2.htm
*  List of OMIM disorder codes - Wikipedia
PIK3CA Gastrointestinal stromal tumor, somatic; 606764; KIT Gastrointestinal stromal tumor, somatic; 606764; PDGFRA Gaucher ... SRY 46XY complete gonadal dysgenesis; 233420; DHH 46XY complete gonadal dysgenesis; 400044; SRY 46XY gonadal dysgenesis, ... ICK Endometrial cancer; 608089; MLH3 Endometrial cancer, familial; 608089; MSH6 Endplate acetylcholinesterase deficiency; ... with vocal cord paresis; 607706; GDAP1 Charcot-Marie-Tooth disease, dominant intermediate 3; 607791; MPZ Charcot-Marie-Tooth ...
  https://en.wikipedia.org/wiki/List_of_OMIM_disorder_codes