*  Uterine tumour resembling ovarian sex cord tumour is an immunohistochemically polyphenotypic neoplasm which exhibits...
... type I were typical endometrial stromal neoplasms with focal areas with a sex cord‐like pattern; in type II tumours, the sex ... Some neoplasms express markers of all these lineages and others of one or two. An origin from displaced gonadal sex cord cells ... and CD99 expression in sex cordstromal tumors and endometrioid ovarian carcinomas resembling sex cordstromal tumors. Hum ... EMA positivity is unusual in ovarian sex cordstromal tumours and argues against a true sex cordstromal neoplasm. Furthermore ...
*  The Biological Activity of AZD2171 in GIST
... clinicaltrials.gov To determine the anti-tumour activity and biological effects of AZD2171 at a dose of 45mg, primarily in GIST ... Sex Cord-gonadal Stromal Tumors. Neoplasms derived from the primitive sex cord or gonadal stromal cells of the embryonic GONADS ... Endometrial Stromal Tumors. Neoplasms of the endometrial stroma that sometimes involve the MYOMETRIUM. These tumors contain ... From the sex cord, there are SERTOLI CELL TUMOR and GRANULOSA CELL TUMOR; from the gonadal stroma, LEYDIG CELL TUMOR and ...
*  J K Chan
ovarian neoplasms*sex cord gonadal stromal tumors*neoplasm staging*glandular and epithelial neoplasms*seer program*papillary ... endometrial neoplasms*survival analysis*germ cell and embryonal neoplasms*uterine hemorrhage*proportional hazards models* ... Prognostic factors responsible for survival in sex cord stromal tumors of the ovary--an analysis of 376 women. Mallory Zhang. ... Prognostic factors responsible for survival in sex cord stromal tumors of the ovary--a multivariate analysis. John K Chan. ...
*  Books by Subject - Lane Medical Library - Stanford University School of Medicine
Germ Cell and Sex Cord Stromal Tumors: Clinical Introduction -- Pathology of Germ Cell Tumors -- Sex Cord Stromal Tumors of the ... Endometrial epithelial neoplasms -- Nonepithelial tumors of uterine corpus -- Gestational trophoblastic disease -- Tumors of ... Gonadal dysgenesis: ovarian function and reproductive health in Turner syndrome / Paul Saenger and David Rodriguez-Buritica -- ... Malignant germ cell tumors and sex cord stromal tumors in adults and children / Jubilee Brown and David M. Gershenson -- 29. ...
*  Paediatric ovarian tumours and their associated cancer susceptibility syndromes | Journal of Medical Genetics
SEX CORD-STROMAL TUMOURS (SCST). Juvenile granulosa cell tumour. General aspects. Juvenile granulosa cell tumours (JGCTs) ( ... The differential diagnosis may include a wide range of neoplasms, including AGCT, JGCT, germ cell tumours, endometrial stromal ... Gonadal tumor in Frasier syndrome: a review and classification. Cancer Prev Res 2015;8:271-6.doi:10.1158/1940-6207.CAPR-14-0415 ... Sex cord tumour with annular tubules (SCTAT). General aspects. Ovarian SCTAT is a rare neoplasm, representing approximately 1%- ...
*  List of MeSH codes (C04) - Wikipedia
... sex cord-gonadal stromal tumors MeSH C04.557.475.750.656 --- granulosa cell tumor MeSH C04.557.475.750.751 --- luteoma MeSH ... endometrial stromal MeSH C04.588.945.418.948.850 --- uterine cervical neoplasms MeSH C04.588.945.418.955 --- vaginal neoplasms ... spinal cord neoplasms MeSH C04.588.614.250.803.342 --- epidural neoplasms MeSH C04.588.614.300 --- cranial nerve neoplasms MeSH ... fallopian tube neoplasms MeSH C04.588.945.418.948 --- uterine neoplasms MeSH C04.588.945.418.948.585 --- endometrial neoplasms ...
*  Shopping Page. Buy or upgrade website. - Healthmatics | Page 18
A sex cord-stromal tumor occurring in the testis and rarely in the ovary. It is predominantly or completely composed of Leydig ... Gonadal interstitial or stromal cell neoplasm composed of only LEYDIG CELLS. These tumors may produce one or more of the ... The oral contraceptive prevents pregnancy by preventing ovulation and by inducing endometrial and cervical changes undesirable ... Sera from tumor-bearing patients block the LAI reaction of their own leukocytes or those of other patients with the same type ...
*  Cystic, mucinous, and serous neoplasms - WOW.com
Sex cord-gonadal stromal. *Leydig cell tumour. *Sertoli cell tumour. *Sertoli-Leydig cell tumour ... Endometrioid tumor. *Uterine papillary serous carcinoma. *Clear cell carcinoma. *Endometrial intraepithelial neoplasia ... This article about a neoplasm is a stub. You can help Wikipedia by expanding it.. *v ... Tumors: female urogenital neoplasia (C51-C58/D25-D28, 179-184/218-221) ...
*  FOXL2 gene | Cancer Genetics Web
Sex Cord-Gonadal Stromal Tumors. *Childhood Cancer. *Up-Regulation. *Single Nucleotide Polymorphism ... Nonovarian tumors such as pancreatic mucinous cystic neoplasms (PMCs), hepatobiliary cystadenomas (HBCs), and mixed epithelial ... A total of 546 tumours (205 cervical, 227 endometrial, 89 ovarian, and 25 vulvar carcinomas) were used to test and validate our ... The term "human germ cell tumors" (GCTs) refers to a heterogeneous group of neoplasms, all with a defined histological ...
*  Ovarian cancer - Wikipedia
... they can cause or occur at the same time as endometrial cancer or breast cancer. Other sex-cord/stromal tumors present with ... a mutation known for its role in gastrointestinal stromal tumor. People with an XY karyotype and ovaries (gonadal dysgenesis) ... They can develop further into a variety of other neoplasms, including choriocarcinoma, yolk sac tumor, and teratoma. They occur ... Symptoms of sex cord-stromal tumors produce hormones that can affect the development of secondary sex characteristics. Sex cord ...
*  Brenner tumour - WOW.com
Sex cord-gonadal stromal. *Leydig cell tumour. *Sertoli cell tumour. *Sertoli-Leydig cell tumour ... Brenner tumors are an uncommon subtype of the surface epithelial-stromal tumor group of ovarian neoplasms. The majority are ... Endometrioid tumor. *Uterine papillary serous carcinoma. *Clear cell carcinoma. *Endometrial intraepithelial neoplasia ... without the characteristic stromal/epithelial pattern of a Brenner tumour.. Eponym. It is named for Fritz Brenner (1877-1969), ...
*  XIX - Female Genital System and the Breast Flashcards by Ian Argel | Brainscape
Biomarker useful for identifying granulosa an other sex cord-stromal tumors, and monitoring treatment. ... cystically dilated endometrial glands, with single layer of endometrial cells (B) crowded branched endometrial glands, with ... Which of the following tumors is most responsive to chemotherapy? (A) gonadal choriocarcinoma (B) gestational choriocarcinoma ( ... Sex cord tumor seen as small, gray to yellow-brown, and solid lesions. May resemble development of testis with tubules, or ...
*  Dysgerminoma - WOW.com
Sex cord-gonadal stromal. *Leydig cell tumour. *Sertoli cell tumour. *Sertoli-Leydig cell tumour ... Trophoblastic neoplasm: Gestational trophoblastic disease*Hydatidiform mole. *Choriocarcinoma. *Placental site trophoblastic ... Endometrioid tumor. *Uterine papillary serous carcinoma. *Clear cell carcinoma. *Endometrial intraepithelial neoplasia ... A tumor of the identical histology but not occurring in the ovary may be described by an alternate name: seminoma in the testis ...
*  Neurosecretory cell | definition of neurosecretory cell by Medical dictionary
2. A large multinucleated (40-60 nuclei) tumor cell characteristic of certain bone and tendon tumors. ... A somatic motor neuron that has its cell body in the ventral (anterior) horn of the gray matter of the spinal cord; its axon ... Arias-Stella cells columnar cells in the endometrial epithelium which have a hyperchromatic enlarged nucleus and which appear ... A cell present in a neoplasm and differentiated from normal tissue cells because of its degree of anaplasia, irregularity of ...
*  Long-Term Effects of Bone Marrow Transplantation: Overview, Immunosuppression and Graft Versus Host Disease After Hematopoietic...
Double-Blind Controlled Study of Efficacy and Safety of Umbilical Cord-Derived Mesenchymal Stromal Cells in the Prophylaxis of ... Clinically assess gonadal function in postpubertal female patients on an annual basis and within 1 year of transplant in ... The known risks of estrogen (ie, predisposition to endometrial and breast cancer [77] ) must be weighed against the risks of ... Ergun-Longmire B, Mertens AC, Mitby P, Qin J, Heller G, Shi W. Growth hormone treatment and risk of second neoplasms in the ...
*  Diseases of the Peritoneum | SpringerLink
Ulbright TM, Kraus FT (1981) Endometrial stromal tumors of extra-uterine tissue. Am J Clin Pathol 76: 371-377PubMedGoogle ... Griffith LM, Carcangiu M (1991) Sex cord tumor with annular tubules associated with endometriosis of the fallopian tube. Am J ... mesothelial neoplasms, miscellaneous primary tumors, and metastatic tumors. The second half of the chapter is devoted to a ... Doty DW, Gruber JS, Wolf GC, Winslow RC (1980) 46 XY pure gonadal dysgenesis: Report of 2 unusual cases. Obstet Gynecol 55: 61S ...
*  International Classification of Diseases for Oncology - Wikipedia
NOS Sex cord/gonadal stromal tumor, NOS Testicular/ovarian stromal tumor M8591/1 Sex cord-gonadal stromal tumor, incompletely ... NOS M8000/6 Neoplasm, metastatic Neoplasm, metastatic Tumor, metastatic Tumor, secondary Tumor embolus M8000/9 Neoplasm, ... NOS Endometrial sarcoma, NOS Endometrial stromal sarcoma, high grade M8931/3 Endometrial stromal sarcoma, low grade ... differentiated M8592/1 Sex cord-gonadal stromal tumor, mixed forms M8593/1 Stromal tumor with minor sex cord elements M8600/0 ...
*  Germ cell tumor | Open Access articles | Open Access journals | Conference Proceedings | Editors | Authors | Reviewers |...
Sex cord-. gonadal stromal. * Sertoli-Leydig cell tumour * Sertoli cell tumour * Leydig cell tumour ... A germ cell tumor (GCT) is a neoplasm derived from germ cells. Germ cell tumors can be cancerous or non-cancerous tumors. Germ ... Endometrioid tumor * Uterine papillary serous carcinoma * Clear cell carcinoma * Endometrial intraepithelial neoplasia ... Tumor marker Embryonal carcinoma 9070/3 20-30 Malignant Poorly differentiated, pleomorphic cells in cords, sheets, or papillary ...
*  Global Library of Women's Medicine - Benign Neoplasms of the Ovary, Fallopian Tube, and Parovarian Region - DOI 10.3843/GLOWM...
Benign Neoplasms of the Ovary, Fallopian Tube, and Parovarian Region ... The sex cord stromal tumors (i.e., granulosa cell tumors and Sertoli-Leydig cell tumors) occur in both benign and malignant ... Bleeding and endometrial hyperplasia may be the problem that brings a patient to a physician, and endometrial cancer has been ... Witschi E: Migration of the germ cells of human embryos from the yolk sac to the primitive gonadal folds. Contrib Embryol 32: ...
*  Is Your Disease on the RARE List™ - If So, More Bad News! | The Addi and Cassi Fund - Niemann Pick Type C
Endolymphatic sac tumors (ELST's) in Von Hippel Lindau (VHL) disease, Endometrial stromal sarcoma, Endomyocardial ... 46 XX Gonadal dysgenesis epibulbar dermoid, 46 XX testicular disorder of sex development, 47 XXX syndrome, 47 XYY syndrome, 49 ... Spinal cord neoplasm, Spinal dysostosis type Anhalt, Spinal intradural arachnoid cysts, Spinal muscular atrophy, Spinal ... Gonadal dysgenesis, Gonadal dysgenesis mixed, Gonadal dysgenesis Turner type, Gonadal dysgenesis XY type associated anomalies, ...
*  Ovary - Wikipedia
Sex cord-gonadal stromal. *Leydig cell tumour. *Sertoli cell tumour. *Sertoli-Leydig cell tumour ... Ovarian neoplasms Germ cell tumor Seen most often in young women or adolescent girls. Other germ cell tumors are: Endodermal ... Endometrioid tumor. *Uterine papillary serous carcinoma. *Endometrial intraepithelial neoplasia. *Uterine clear-cell carcinoma ... Krukenberg tumor Society and culture[edit]. Cryopreservation[edit]. Cryopreservation of ovarian tissue, often called ovarian ...
*  American Urological Association - Müllerian Lesions
Sex Cord Stromal Tumors * Sex Cord Stromal Tumors General Features * Leydig Cell Tumor ... Histology: requires presence of endometrial glands (G), stroma (S) and recent or old hemorrhage for diagnosis (image A). ... Papillary Urothelial Neoplasm of Low Malignant Potential * Papillary Urothelial Carcinoma, Low Grade ... Mixed Gonadal Dysgenesis * True Hermaphroditism * Tuberculous Epididymo-Orchitis * Brucella Orchitis * Testicular Infarct ...
*  Protocols and Video Articles Authored by So Young Lee (Translated to Japanese)
Apr, 2012 , Pubmed ID: 22536475 Wilms' tumor is one of the most frequent malignant neoplasms in childhood. Advances in ... Phosphatidic Acid Induces Decidualization by Stimulating Akt-PP2A Binding in Human Endometrial Stromal Cells The FEBS Journal. ... Suppression of the hypothalamic-pituitary-gonadal axis has been widely utilized for the management of gonadal-hormone-dependent ... Jan, 2015 , Pubmed ID: 25236779 The present review has been focused largely on the sex type differences in beef quality among ...
*  Immunohistochemical study of testicular sex cord-stromal tumors, including staining with anti-inhibin antibody. - The Christie...
Inhibin is a peptide hormone produced by ovarian granulosa cells and testicular Sertoli cells. Ovarian granulosa cell and other sex cord-stromal tumors usually exhibit positive immunohistochemical staining with antiinhibin antibodies, and this may be valuable in differentiating these neoplasms from histologic mimics. In the present study, we investigated the immunohistochemical staining of testicular sex cord-stromal tumors using antiinhibin. Immunostaining with CAM5.2, vimentin, S-100 protein, desmin, epithelial membrane antigen (EMA), carcinoembryonic antigen (CEA), and placental alkaline phosphatase (PLAP) also was performed because few studies have investigated in detail the immunophenotype of testicular sex cord-stromal tumors. Fifteen ...
*  Paclitaxel and Carboplatin or Bleomycin Sulfate, Etoposide Phosphate, and Cisplatin in Treating Patients With Advanced or...
PRIMARY OBJECTIVES:. I. To assess the activity of paclitaxel and carboplatin with respect to progression free survival (using bleomycin, etoposide, and cisplatin [BEP] as a reference) for newly diagnosed advanced or recurrent chemonaive ovarian sex cord-stromal tumors.. SECONDARY OBJECTIVES:. I. To estimate the toxicity of paclitaxel and carboplatin, and bleomycin, etoposide, and cisplatin in this patient population.. II. To estimate overall survival for paclitaxel and carboplatin relative to that of BEP.. III. To evaluate response rate in the subset of patients with measurable disease.. TERTIARY OBJECTIVES:. I. To collect fixed and/or frozen tumor tissue for future translational research studies.. II. To explore the utility of inhibin A and inhibin B as prognostic and predictive biomarkers for ovarian sex cord-stromal tumors and to examine ...
*  Diverse phenotypic profile of uterine tumors resembling ovarian sex cord tumors: an immunohistochemical study of 12 cases. - de...
en] BACKGROUND: Uterine tumors resembling ovarian sex cord tumors (UTROSCTs) are rare neoplasms thought to be of putative endometrial stromal origin and solely composed of sex cord elements. Our study aimed to delineate the immunophenotype of these tumors and to verify whether their morphology reflects true sex cord-like differentiation. DESIGN: Representative paraffin blocks from 12 UTROSCTs were selected after confirmation of the diagnosis. Cords and/or trabeculae were seen in all tumors, whereas tubules, diffuse areas, and a retiform pattern were present in 9, 6, and 2 cases, respectively. Tumors were stained for sex cord (inhibin, calretinin, WT1, and melan-A), epithelial (KL1 and epithelial membrane ...
*  Testicular sex cord-stromal tumor in a boy with 2q37 deletion syndrome | BMC Medical Genomics | Full Text
This study provides novel insight into the genotype-phenotype correlations of the rare chromosomal disorder del2q37 syndrome. First, this case manifests typical clinical features of del2q37 syndrome, while the phenotypic presentation because of the 1p36 duplication was less evident except for intelligence disability [18]. This finding suggests that haploinsufficiency of the genes at 2q37, rather than the segmental duplications of 1p36 or 20p12, shows dominant effects on the phenotypic presentation. Specific gene functions of GPCPD1 and the duplication of 20p12 remain to be clarified, structural variations at 20p14.3, wherein this gene is located, were identified in healthy individuals of Korean ethnicity [19]. Therefore, the 20p14.3 duplication spanning the GPCPD1 locus was unlikely to alter the phenotype of del2q37 syndrome and to produce the carcinogenic condition. While the present case did not show profound phenotype of intellectual disability compared to other cases in the literature, we ...
*  ClinMed International Library
Uterine tumour resembling an ovarian sex cord tumour (UTROSCT) is a rare neoplastic lesion. It has been described for the first time in 1945 by Morehead.
*  Combined comparative genomic hybridization and transcriptomic analyses of ovarian granulosa cell tumors point to novel...
Ovarian granulosa cell tumors (GCTs) are the most frequent sex cord-stromal tumors, and account for more than 5% of ovarian cancers [1]. Two different forms, juvenile and adult, have been described based on the age of onset and histopathological features [2]. GCTs tend to be low-grade malignancies, but can recur up to 40 years after primary tumor resection [3]. Various studies have revealed that a somatic mutation leading to the p.C134W substitution in the transcription factor FOXL2 appears in , 95% of adult-type GCTs [4].. Transactivation studies have suggested that the p.C134W mutation could perturb the functional interaction between FOXL2 with SMAD3 [5] and FOXL2 activity in other systems [6]. This variant is also deficient in its ability to promote apoptosis [7] and displays a mild loss-of-function on targets involved in cell cycle and DNA-damage repair [8].. We have recently performed a transcriptomic ...
*  Granulosa-Theca Cell Tumors Follow-up: Further Outpatient Care, Inpatient & Outpatient Medications, Transfer
Three major types of ovarian neoplasms are described, with epithelial cell tumors (>70%) comprising the largest group of tumors. Germ cell tumors occur less frequently (20%), while sex cord-stromal tumors make up the smallest proportion, accounting for approximately 8% of all ovarian neoplasms.
*  Ovarian fibroma - Wikipedia
The ovarian fibroma, also fibroma, is a benign sex cord-stromal tumour. Ovarian fibromas represent 4% of all ovarian neoplasms. They tend to occur mostly during perimenopause and postmenopause, the median age having been reported to be about 52 years, and they are rare in children. Lesions tend to be asymptomatic. If symptoms are present, the most common one is abdominal pain. On gross pathology, they are firm and white or tan. On microscopic examination, there are intersecting bundles of spindle cells producing collagen. There may be thecomatous areas (fibrothecoma). The presence of an ovarian fibroma can cause ovarian torsion in some cases. Diagnosis is usually made by ultrasonography showing a solid ovarian lesion, or, on some occasions, mixed tumors with solid and cystic components. Computed tomography and magnetic resonance imaging can also be used to diagnose fibromas. In a series of 16 patients, 5 ...
*  Thecoma - Wikipedia
Thecomas or theca cell tumors are benign ovarian neoplasms composed only of theca cells. Histogenetically they are classified as sex cord-stromal tumours. They are typically estrogen-producing and they occur in older women (mean age 59; 84% after menopause). (They can, however, appear before menopause.) 60% of patients present with abnormal uterine bleeding, and 20% have endometrial carcinoma. Grossly, the tumour is solid and yellow. Grossly and microscopically, it consists of the ovarian cortex. Microscopically, the tumour cells have abundant lipid-filled cytoplasm. Okada I, Nakagawa S, Takemura Y, et al. (October 2004). "Ovarian thecoma associated in the first trimester of pregnancy". J. Obstet. Gynaecol. Res. 30 (5): 368-71. doi:10.1111/j.1447-0756.2004.00212.x. PMID 15327450 ...
*  Androblastomas - Medical Dictionary online-medical-dictionary.org
A sex cord-gonadal stromal Tumor consists of Leydig Cells; Sertoli Cells; and Fibroblasts in varying proportions and degree of differentiation. Most such Tumors produce Androgens in the Leydig Cells, formerly known as androblastoma or arrhenoblastoma. Androblastomas occur in the Testis or the Ovary causing precocious masculinization in the males, and defeminization, or Virilization (Virilism) in the females. In some cases, the Sertoli Cells produce Estrogens ...
*  Patent US5885294 - Apparatus and method for anchoring a cord-like element to a workpiece - Google Patents
A novel system and method for anchoring a suture or other cord-like element to a bone or other workpiece. The system comprises a drill for forming an undercut hole in a bone or other workpiece, an anchor for securing a suture or other cord-like element in the undercut hole in the bone or other workpiece, and an inserter for deploying the anchor in the undercut hole in the bone or other workpiece.
*  Spinal cord tumors, Information about Spinal cord tumors
If the tumor is malignant and has spread into the spine from other parts of the body, treatment depends on the type of cancer it is. Surgery is usually the first step in treating cancerous and noncancerous tumors outside the spinalcord. Tumors inside the spinal cord may not be able to be completely removedwith surgery. If they can't be removed, radiation and chemotherapy treatments may ease symptoms. Treatment also may include pain relievers and drugs to lessen swelling around the tumor, and relieve pressure on the spinal cord.. Early diagnosis and treatment can produce a higher success rate. Long-term survival depends on the tumor's type, location, and size. Surgery to remove thebone around the spinal cord can ease pressure on the spinal nerves and nervepathways, which will usually ease pain and other symptoms; however, it may make walking more difficult. Physical therapy and rehabilitation may help.. Since ...
*  Single cell triggers fibroid uterine tumor - UPI.com
U.S. researchers say they've identified the molecular trigger of fibroid uterine tumors -- a single stem cell develops a mutation and grows uncontrollably.
*  Treatment of Pediatric Spinal Cord Tumors - Pediatric Spinal Cord Tumors
Surgery is performed to remove or reduce the size of the tumor and alleviate the pressure ont he spinal column caused by the tumor.
*  Spinal cord tumors: new views and future directions.
Spinal cord tumors are uncommon neoplasms that, without treatment, can cause significant neurologic morbidity and mortality. The historic classification of spine tumors is based on the use of myelography with 3 main groups: (1) extramedullary extradu
*  Vocal Cord Tumor: Risk Factors
Another name for Vocal Cord Tumor is Laryngeal Cancer. Risk factors for laryngeal cancer include: * Age over 50 * Alcohol abuse * Chewing tobacco * Gastroesophageal ...
*  Brain and Spinal Cord Tumors in Children
Whether your child has just been diagnosed with a brain or spinal cord tumor, is going through treatment, or is trying to stay well after treatment, this detailed guide can help you find the answers you need.
*  Key Statistics for Brain and Spinal Cord Tumors
The American Cancer Society's most recent estimates and statistics for brain and spinal cord tumors in the United States are located here.
*  Targeted Therapy for Adult Brain and Spinal Cord Tumors
Targeted drugs work differently on brain and spinal cord tumors than standard chemotherapy drugs. They often have less severe side effects. Learn more here.
*  Rehabilitation for Spinal Cord Tumors | Pelisyonkis Langone Health- pelisyonkis.info
Pelisyonkis Langone rehabilitation experts use medication and physical and occupational therapy to help people recover from spinal cord tumors. Read more.
*  Research - Canada's Michael Smith Genome Sciences Centre
The oncogenic roles of DICER1 RNase IIIb domain mutations in ovarian Sertoli-Leydig cell tumors." Wang Y, Chen J, Yang W, Mo F, Senz J, Yap D, Anglesio MS, Gilks B, Morin GB, Huntsman DG. Neoplasia. 2015 Aug;17(8):650-60.. "MEF2B mutations in non-Hodgkin lymphoma dysregulate cell migration by decreasing MEF2B target gene activation." Pon JR, Wong J, Saberi S, Alder O, Moksa M, Grace Cheng SW, Morin GB, Hoodless PA, Hirst M, Marra MA. Nat Commun. 2015 Aug 6;6:7953. "Cancer-associated somatic DICER1 hotspot mutations cause defective miRNA processing and reverse-strand expression bias to predominantly mature 3p strands through loss of 5p strand cleavage." Anglesio MS, Wang Y, Yang W, Senz J, Wan A, Heravi-Moussavi A, Salamanca C, Maines-Bandiera S, Huntsman DG, Morin GB. J Pathol. 2013 Feb;229(3):400-9.. "Interaction of cyclin-dependent kinase 12/CrkRS with cyclin K1 is required for the phosphorylation of the C-terminal domain of RNA polymerase II." Cheng SW, Kuzyk MA, Moradian A, Ichu TA, ...
*  Ovarian Dysgerminomas: Background, Pathophysiology, Epidemiology
The 3 major types of ovarian tumors are epithelial, sex cord, and germ cell. Epithelial cell tumors represent the majority of all ovarian neoplasms (82%).
*  What Happens After Treatment for Brain and Spinal Cord Tumors in Children?
After treatment, the main concerns for most families are the immediate and long-term effects of the tumor and its treatment, and concerns about the tumor still being present or coming back.
*  Doctors and Staff
Johns Hopkins doctors are experts in the treatment and care of children with brain and spinal cord tumors, providing the most effective and safest treatment available.