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*  UBC scientists in the global race to cure diabetes with stem cells; the Chinese competition | Vancouver Sun
... a team of Chinese scientists reported success in using human diabetics' own stem cells to reverse dependence on insulin. ... a team of Chinese scientists reported success in using human diabetics' own stem cells to reverse dependence on i... ... a team of Chinese scientists reported success in using human diabetics' own stem cells to reverse dependence on i... ... scientists announced they'd used human embryonic stem cell transplants to reverse diabetes in mice with the disease, ...
  http://vancouversun.com/news/staff-blogs/ubc-scientists-in-the-global-race-to-cure-diabetes-with-stem-cells-the-chinese-competition
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
The pancreatic islet is a unique micro-organ composed of several hormone secreting endocrine cells such as beta-cells (insulin ... Access to this online collection is currently provided to over 200 clinicians and scientists involved in type 1 diabetes ... Modulation of mast cell degranulation by drugs and toxicants may have positive or adverse effects on human health. Mast cell ... variations in the consistency of islet yield and quality from any given rodent strain limit the extent and feasibility of ...
  https://www.jove.com/visualize/abstract/23077547/glucose-decouples-intracellular-ca2-activity-from-glucagon-secretion
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
The pancreatic islet is a unique micro-organ composed of several hormone secreting endocrine cells such as beta-cells (insulin ... Access to this online collection is currently provided to over 200 clinicians and scientists involved in type 1 diabetes ... to study the genetics and cell biology of astrocytoma pathogenesis in vitro and in vivo and may be useful in preclinical drug ... The transposome, provided as a DNA/transposase protein complex, is introduced by electroporation into the prototrophic strain, ...
  https://www.jove.com/visualize/abstract/24621811/targeting-sur1abcc8-type-neuroendocrine-katp-channels-pancreatic
*  No more insulin injections? Encapsulated pancreatic cells offer possible new diabetes treatment
In patients suffering from Type 1 diabetes, the immune system attacks the pancreas, eventually leaving patients without the ... Patients with type 1 diabetes have their insulin secreting cells destroyed by the immune system and require daily insulin ... They chose a strain of mice with a strong immune system and implanted human islet cells encapsulated in TMTD into a region of ... Six novel chromosomal regions identified by scientists leading a large, prospective study of children at risk for type 1 ...
  https://medicalxpress.com/news/2016-01-insulin-encapsulated-pancreatic-cells-diabetes.html
*  How to Find Your Body Type « Wonder How To
... the body produces antibodies that attack insulin-secreting cells in the pancreas. Doctors often diagnose this type of diabetes ... Ever since this realization, scientists have worked to find the trigger that sets the immune system off. Scientists b ...more ... Lessen the strain from clapping push ups If you're finding that performing your usual push up routine is not giving you results ... Drug-resistant bacteria have made curing some infections challenging, if not nearly impossible. By 2050, it's estimated that 10 ...
  https://tag.wonderhowto.com/how-to-find-your-body-type/
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
Type 1 diabetes mellitus (T1DM) is an autoimmune disease caused by immune-mediated destruction of insulin-secreting ? cells of ... one strain into another mouse strain recipient is limited as a model for chronic rejection in humans because the acute cell- ... to study the genetics and cell biology of astrocytoma pathogenesis in vitro and in vivo and may be useful in preclinical drug ... For almost 30 years, scientists have demonstrated that human fetal ICCs transplanted under the kidney capsule of nude mice ...
  https://www.jove.com/visualize/abstract/24594640/ex-vivo-expanded-human-regulatory-t-cells-delay-islet-allograft
*  Streptozotocin - Wikipedia
Rerup CC (1970). "Drugs producing diabetes through damage of the insulin secreting cells". Pharmacol Rev. 22 (4): 485-518. PMID ... The drug was discovered in a strain of the soil microbe Streptomyces achromogenes by scientists at the drug company Upjohn (now ... as well as type 2 diabetes or type 1 diabetes with multiple low doses. Streptozotocin is approved by the U.S. Food and Drug ... the cells that normally regulate blood glucose levels by producing the hormone insulin. This suggested the drug's use as an ...
  https://en.wikipedia.org/wiki/Streptozotocin
*  2009 April 15 : Target Health Global
Type 1 diabetes is a chronic disease in which the immune system attacks the insulin-secreting beta cells in the pancreas; the ... TR: Are there drugs that can protect against cancer?. KO: Sometimes taking drugs like tamoxifen [a drug that interferes with ... Immune reboot: To reboot the immune system, scientists harvest hematopoietic stem cells, like the one pictured here, from a ... "And during that year of recovery, a patient typically puts a greater strain on our health care system, not to mention their ...
  http://blog.targethealth.com/2009/04/15/
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
The β-cells of the pancreatic islets of Langerhans are responsible for appropriately secreting insulin in response to elevated ... strain GV3101 showed the highest protein production compared to Agrobacteria laboratory strains LBA4404 and C58C1 and wild-type ... Modulation of mast cell degranulation by drugs and toxicants may have positive or adverse effects on human health. Mast cell ... For almost 30 years, scientists have demonstrated that human fetal ICCs transplanted under the kidney capsule of nude mice ...
  https://www.jove.com/visualize/abstract/22479612/isosteviol-has-beneficial-effects-on-palmitate-induced-cell
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
Type 1 diabetes is caused by T cell-mediated autoimmune destruction of insulin-producing cells in the pancreas. Until now ... The β-cells of the pancreatic islets of Langerhans are responsible for appropriately secreting insulin in response to elevated ... Access to this online collection is currently provided to over 200 clinicians and scientists involved in type 1 diabetes ... Drug Design, optimization (mathematics), Amino Acids, Peptides, and Proteins, De novo protein and peptide design, Drug design, ...
  https://www.jove.com/visualize/abstract/26075596/the-identification-novel-protein-protein-interactions-liver-that
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... the effect of specific transcellular interactions on the insulin secreting capacity and responsiveness of beta cells is ... this approach is suitable for type I, type II, GPI-linked cell surface receptors and secreted proteins but not for multipass ... Drug Design, optimization (mathematics), Amino Acids, Peptides, and Proteins, De novo protein and peptide design, Drug design, ... There are currently ,20,000 registered scientists from over 100 countries who are using the on-line I-TASSER server. ...
  https://www.jove.com/visualize/abstract/22509312/reduced-polymorphism-domains-involved-protein-protein
*  Genetherapy
Large quantities of cells, such as dopamine-secreting neurons for the treatment of Parkinson disease and insulin-secreting ... In Nature, scientists published on a more refined type of CRISPR gene editing that can alter a single bit of DNA without ... In 2009 the U.S. Food and Drug Administration approved the first clinical trial designed to test a human embryonic stem cell- ... Available genomes are human (hg19 & hg38), mouse (mm10), and yeast (strain w303). ...
  https://www.genetherapy.me/page/3
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*  Iraq Academic Scientific Journals
The histopathological studies also indicated that AEIP is effective in regeneration of insulin secreting β-cells. Studies ... Effect of Metronidazole drug in the Levels of some Pregnancy Hormones during Blastocyst Implantation in Rat Uterus تاثير عقار ... Some oxidant- antioxidant Studies in Type-II Diabetic Patient's ) دراسة بعض مضادات الاكسدة- الاكسدة في مرضى النوع الثاني لداء ... This study was conducted to serologically, biologically and molecularly characterize the ordinary strain of Potato virus S ( ...
  https://www.iasj.net/iasj?func=issueTOC&isId=5719&uiLanguage=en
*  RegenerativeMedicine.net - Article Archives
Vanderbilt University scientists have found evidence that the insulin-secreting beta cells of the pancreas, which are either ... and Cancer Brain Cancer Cells Hide While Drugs Seek Type 1 Diabetes: A Treatment's in Sight? Precise Electronic Drug Release ... Day Help Slow Down Aging Process New Antibiotic Effective Against Drug-Resistant Bacteria Mutations That Allow Bird Flu Strain ... Cell Reprogramming How Cells in the Nose Detect Odors Scientists Develop Single-Cell Imaging to Watch the Cell Clock New Type ...
  http://regenerativemedicine.net/NewsletterArchives.asp?qEmpID=8998&qCat=USN
*  Featured Papers
... regeneration of beta cell tissue by stimulating the conversion of immature precursor cells into insulin-secreting beta cells. ... DZD scientists at Helmholtz Zentrum München are exploring new strategies to prevent the onset of type 1 diabetes. They have ... in which mature beta cells are derived in the laboratory from stem cells. Second, they provide targets for new drugs that ... This suggests that oral ingestion of one specific strain may. serve as a novel therapeutic approach to improve glucose- ...
  https://www.dzd-ev.de/en/latest/featured-papers/index.html
*  FARA - Grants Awarded
... the Betz cells of the motor cortex, sensory peripheral nerves, heart, and the insulin-secreting ß-cells of the pancreas-while ... Award type: General Research Grant Grant Title: A human iPSC-based cardiac model of Friedreich's ataxia for drug discovery and ... significantly the firefly luciferase expression in the 300 GAA strain to levels similar to those showed by the 9 GAA strain. ... These iPSCs can then in turn be differentiated into any cell type, including the cell types affected in Friedreich's ataxia ( ...
  http://curefa.org/grant-awards
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  http://farsis.com.ua/blog/sovety-po-remontu/nr-start/