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*  UBC scientists in the global race to cure diabetes with stem cells; the Chinese competition | Vancouver Sun
... a team of Chinese scientists reported success in using human diabetics' own stem cells to reverse dependence on insulin. ... a team of Chinese scientists reported success in using human diabetics' own stem cells to reverse dependence on i... ... a team of Chinese scientists reported success in using human diabetics' own stem cells to reverse dependence on i... ... scientists announced they'd used human embryonic stem cell transplants to reverse diabetes in mice with the disease, ...
  http://vancouversun.com/news/staff-blogs/ubc-scientists-in-the-global-race-to-cure-diabetes-with-stem-cells-the-chinese-competition
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
The pancreatic islet is a unique micro-organ composed of several hormone secreting endocrine cells such as beta-cells (insulin ... Access to this online collection is currently provided to over 200 clinicians and scientists involved in type 1 diabetes ... Modulation of mast cell degranulation by drugs and toxicants may have positive or adverse effects on human health. Mast cell ... variations in the consistency of islet yield and quality from any given rodent strain limit the extent and feasibility of ...
  https://www.jove.com/visualize/abstract/23077547/glucose-decouples-intracellular-ca2-activity-from-glucagon-secretion
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
The pancreatic islet is a unique micro-organ composed of several hormone secreting endocrine cells such as beta-cells (insulin ... Access to this online collection is currently provided to over 200 clinicians and scientists involved in type 1 diabetes ... to study the genetics and cell biology of astrocytoma pathogenesis in vitro and in vivo and may be useful in preclinical drug ... The transposome, provided as a DNA/transposase protein complex, is introduced by electroporation into the prototrophic strain, ...
  https://www.jove.com/visualize/abstract/24621811/targeting-sur1abcc8-type-neuroendocrine-katp-channels-pancreatic
*  No more insulin injections? Encapsulated pancreatic cells offer possible new diabetes treatment
In patients suffering from Type 1 diabetes, the immune system attacks the pancreas, eventually leaving patients without the ... Diabetes is one of the leading causes of death. Patients with type 1 diabetes have their insulin secreting cells destroyed by ... More information: Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent ... They chose a strain of mice with a strong immune system and implanted human islet cells encapsulated in TMTD into a region of ...
  https://medicalxpress.com/news/2016-01-insulin-encapsulated-pancreatic-cells-diabetes.html
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
Type 1 diabetes mellitus (T1DM) is an autoimmune disease caused by immune-mediated destruction of insulin-secreting ? cells of ... Functional beta cell mass is determined by the anatomical beta cell mass as well as the ability of the beta cells to respond to ... one strain into another mouse strain recipient is limited as a model for chronic rejection in humans because the acute cell- ... to study the genetics and cell biology of astrocytoma pathogenesis in vitro and in vivo and may be useful in preclinical drug ...
  https://www.jove.com/visualize/abstract/24594640/ex-vivo-expanded-human-regulatory-t-cells-delay-islet-allograft
*  Streptozotocin - Wikipedia
Rerup CC (1970). "Drugs producing diabetes through damage of the insulin secreting cells". Pharmacol Rev. 22 (4): 485-518. PMID ... The drug was discovered in a strain of the soil microbe Streptomyces achromogenes by scientists at the drug company Upjohn (now ... This suggested the drug's use as an animal model of diabetes, and as a medical treatment for cancers of the beta cells. In the ... In the mid-1960s, streptozotocin was found to be selectively toxic to the beta cells of the pancreatic islets, the cells that ...
  https://en.wikipedia.org/wiki/Streptozotocin
*  2009 April 15 : Target Health Global
Type 1 diabetes is a chronic disease in which the immune system attacks the insulin-secreting beta cells in the pancreas; the ... TR: Are there drugs that can protect against cancer?. KO: Sometimes taking drugs like tamoxifen [a drug that interferes with ... Because this form of diabetes is an autoimmune disease, scientists have been looking for ways to stop the immune system's ... "And during that year of recovery, a patient typically puts a greater strain on our health care system, not to mention their ...
  http://blog.targethealth.com/2009/04/15/
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
Medicine, Issue 64, Physiology, beta cell, gene expression, islet, diabetes, insulin secretion, proliferation, adenovirus, rat ... The β-cells of the pancreatic islets of Langerhans are responsible for appropriately secreting insulin in response to elevated ... Modulation of mast cell degranulation by drugs and toxicants may have positive or adverse effects on human health. Mast cell ... For almost 30 years, scientists have demonstrated that human fetal ICCs transplanted under the kidney capsule of nude mice ...
  https://www.jove.com/visualize/abstract/22479612/isosteviol-has-beneficial-effects-on-palmitate-induced-cell
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
Medicine, Issue 63, Physiology, type 1 diabetes, histology, H&E, immunohistochemistry, insulin, beta-cells, glucagon, alpha- ... The β-cells of the pancreatic islets of Langerhans are responsible for appropriately secreting insulin in response to elevated ... Access to this online collection is currently provided to over 200 clinicians and scientists involved in type 1 diabetes ... Drug Design, optimization (mathematics), Amino Acids, Peptides, and Proteins, De novo protein and peptide design, Drug design, ...
  https://www.jove.com/visualize/abstract/26075596/the-identification-novel-protein-protein-interactions-liver-that
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... the effect of specific transcellular interactions on the insulin secreting capacity and responsiveness of beta cells is ... INS-1 cells, extracellular contact, transmembrane protein, transcellular interactions, insulin secretion, diabetes, cell ... Drug Design, optimization (mathematics), Amino Acids, Peptides, and Proteins, De novo protein and peptide design, Drug design, ... There are currently ,20,000 registered scientists from over 100 countries who are using the on-line I-TASSER server. ...
  https://www.jove.com/visualize/abstract/22509312/reduced-polymorphism-domains-involved-protein-protein
*  How to Find Your Body Type « Wonder How To
... the body produces antibodies that attack insulin-secreting cells in the pancreas. Doctors often diagnose this type of diabetes ... Ever since this realization, scientists have worked to find the trigger that sets the immune system off. Scientists b ...more ... Lessen the strain from clapping push ups If you're finding that performing your usual push up routine is not giving you results ... How To: The Official One UI Beta Just Went Live for US Galaxy S9 Users - Here's How to Get It ...
  https://tag.wonderhowto.com/how-to-find-your-body-type/
*  Genetherapy
... neurons for the treatment of Parkinson disease and insulin-secreting pancreatic beta cells for the treatment of diabetes, could ... were awarded on Tuesday to a Scottish veterinarian who developed the drug propofol, two scientists who discovered the hidden ... Available genomes are human (hg19 & hg38), mouse (mm10), and yeast (strain w303). ... The resulting inner cell mass cells are plated onto cells that will supply support. The inner cell mass cells attach and expand ...
  https://www.genetherapy.me/page/3
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*  Featured Papers
... regeneration of beta cell tissue by stimulating the conversion of immature precursor cells into insulin-secreting beta cells. ... The brain response to peripheral insulin declines with age: a.... DZD scientists at the Institute for Diabetes Research and ... in which mature beta cells are derived in the laboratory from stem cells. Second, they provide targets for new drugs that ... This suggests that oral ingestion of one specific strain may. serve as a novel therapeutic approach to improve glucose- ...
  https://www.dzd-ev.de/en/latest/featured-papers/index.html
*  FARA - Grants Awarded
... the Betz cells of the motor cortex, sensory peripheral nerves, heart, and the insulin-secreting ß-cells of the pancreas-while ... "Central role and mechanisms of beta-cell dysfunction and death in friedreich ataxia-associated diabetes." Ann Neurol. 72:971- ... Drug Discovery (2), Gene and Stem Cell Therapy (1), Lead Candidates (1), Mechanisms or Pathway of Disease (6), Cell and Animal ... significantly the firefly luciferase expression in the 300 GAA strain to levels similar to those showed by the 9 GAA strain. ...
  http://curefa.org/grant-awards
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  http://farsis.com.ua/blog/sovety-po-remontu/nr-start/