*  Genetic Analysis of Resistance to Viral Infection - Bruce Beutler
The present application extends a successful multifaceted investigation of host resistance to viral infection. The strengths of ... Basic scientific discovery in these areas will pave the way to the design of effective anti-viral drugs and vaccines, and has ... Genetic Analysis of Resistance to Viral Infection Beutler, Bruce A. University of Texas Sw Medical Center Dallas, Dallas, TX, ... 2016) Insulin resistance and diabetes caused by genetic or diet-induced KBTBD2 deficiency in mice. Proc Natl Acad Sci U S A 113 ...
  http://grantome.com/grant/NIH/P01-AI070167-06A1
*  Growing Threat Of Drug Resistance Demands Systematic Global Response, Report
The growing threat of drug resistance, which will increasingly leave more and more people vulnerable to diseases that were once ... Spotlight on: MRSA / Drug Resistance. * Antibiotic resistance: how has it become a global threat to public health? ... "Drug resistance is a natural occurrence, but careless practices in drug supply and use are hastening it unnecessarily.". ... Thus the key to slowing down the emergence of drug resistance, is to manage the use of drugs carefully, eg only give them when ...
  https://www.medicalnewstoday.com/articles/192008.php?sr
*  MOR/0.2R | Creative Bioarray
MOR/0.2R accumulate lower levels of doxorubicin than the parent line and have been shown to overexpress multi drug resistance ... Expression of a 190kDa membrane protein associated with the degree of drug-resistance has been indicated. Cells grow as easily ... The drug resistant cell line MOR/0.2R has been derived from the parent line, MOR, by continuous exposure to increasing ...
  https://www.creative-bioarray.com/MOR-02R-CSC-C9510J-item-42499.htm
*  Drug Resistance | Understanding HIV/AIDS | AIDSinfo
Drug resistance can cause HIV treatment to fail. *A person can initially be infected with drug-resistant HIV or develop drug- ... Cross resistance is when resistance to one HIV medicine causes resistance to other medicines in the same HIV drug class. (HIV ... What is drug-resistance testing?. Drug-resistance testing is done to identify which, if any, HIV medicines won't be effective ... If drug-resistance testing shows that the HIV regimen isn't effective because of drug resistance, the test results can be used ...
  https://aidsinfo.nih.gov/understanding-hiv-aids/fact-sheets/21/56/drug-resistance/
*  What dose of medication is best to prevent the evolution of drug resistance? | Penn State University
... with the highest tolerable dose of anti-microbe medications may not be best for preventing the evolution of drug resistance in ... Day and Read showed that the optimal approach to combatting the evolution of drug resistance will be either to use the highest ... "Killing all of the infecting microbes obviously stops any further evolution of drug resistance, but we can't do this in every ... If a small number of microbes are already resistant to treatment, or if drug resistance arises by chance, high doses of ...
  http://news.psu.edu/story/389559/2016/01/28/research/what-optimal-dose-medication-prevent-evolution-drug-resistan
*  World Health Organization, Amid concern over drug resistance, Mekong countries call for accelerated action to eliminate malaria...
To date, resistance has been detected in five of the six GMS countries. The best way to address the threat posed by drug ... Amid concern over drug resistance, Mekong countries call for accelerated action to eliminate malaria before 2030. SEAR/PR/1673 ... Resistance to antimalarial drugs, unless addressed with urgency, could undermine these gains. Malaria is a life-threatening ... The call comes amid concern over resistance of malaria parasites to antimalarial drugs, including artemisinin-the core compound ...
  http://www.searo.who.int/mediacentre/releases/2017/1673/en/
*  Drug resistance - Wikipedia
Tolerance and Resistance Cosmetics Database HCMV drug resistance mutations tool Combating Drug Resistance - An informative ... "Drug resistance develops naturally, but careless practices in drug supply and use are hastening it unnecessarily." - Center for ... The chances of drug resistance can sometimes be minimized by using multiple drugs simultaneously. This works because individual ... Antibiotic resistance Fecal bacteriotherapy Mass drug administration Multidrug resistance Pharmacoepidemiology Small multidrug ...
  https://en.wikipedia.org/wiki/Drug_resistance
*  Microbial Drug Resistance
The international peer-reviewed journal covering the global spread and threat of multi-drug resistant clones of major pathogens ...
  http://www.liebertpub.com/subscribe/addtocart/microbial-drug-resistance/44/
*  Microbial Drug Resistance
The international peer-reviewed journal covering the global spread and threat of multi-drug resistant clones of major pathogens ... Microbial Drug Resistance (MDR) is an international, peer-reviewed journal that covers the global spread and threat of multi- ... Microbial Drug Resistance is under the editorial leadership of Editor Alexander Tomasz, PhD, The Rockefeller University, ... The Journal addresses the serious challenges of trying to decipher the molecular mechanisms of drug resistance. MDR provides a ...
  http://www.liebertpub.com/MDR/
*  WHO | Responding to antimalarial drug resistance
Resistance to antimalarial medicines is a threat to global efforts to control and eliminate malaria. Protecting the efficacy of ... Preventing and containing antimalarial drug resistance. Several factors influence the emergence and spread of drug resistant ... The Greater Mekong Subregion has long been the epicentre of antimalarial drug resistance. P. falciparum resistance to ... Countries where resistance to artemisinins or to ACT partner drugs is reported need to intensify malaria control in order to ...
  http://www.who.int/malaria/areas/drug_resistance/overview/en/
*  Drug Resistance
An easy-to-use directory for life science and biomedical research products. Find special deals on products, order catalogs and browse product lines from suppliers of reagents, antibodies, laboratory equipment, and more.
  http://www.biosupplynet.com/cfdocs/products/prod_supp.cfm?prod_id=268
*  Drug resistance continued: Malaria | HealthMap
Resistance Open: Battling the 'Post-Antibiotic Era'. November 18, 2015 Doctor, Meet Resistance The origins of Resistance Open ... Drug resistance continued: Malaria. Sep 22, 2011 , Anna Tomasulo , Outbreak News by DFID - UK Department for International ... Antimalarial Drug Resistance in Cambodia. January 27, 2016 An NIH study published in The Lancet Infectious Disease earlier this ... Antimalarial Drug Resistance in Cambodia. An NIH study published in The Lancet Infectious Disease earlier this month indicates ...
  http://www.healthmap.org/site/diseasedaily/article/drug-resistance-continued-malaria-92211
*  HIV Antiretroviral Drug Resistance Testing, Genotypic
... used to determine whether the HIV strain infecting an individual is resistant or has developed resistance to one or more drugs ... HIV antiretroviral drug resistance testing is used to help select a drug regimen that will likely be effective in treating a ... 1995-2012). Test ID: GHIVR HIV-1 Genotypic Drug Resistance Mutation Analysis, with Reflex to Phenotypic Drug Resistance ... is a better indicator of the level of HIV drug resistance.. HIV genotypic resistance testing cannot detect unknown resistance ...
  https://labtestsonline.org/tests/hiv-antiretroviral-drug-resistance-testing-genotypic
*  WPRO | Drug Resistance
Antimicrobial resistance is a global public health threat with resistant microorganisms reaching alarming levels in all six WHO ... Resistance occurs when microorganisms become resistant to antimicrobial medicines and the antimicrobials no longer work in ... There is a need for urgent, concerted actions with multiple stakeholders to contain antimicrobial resistance at the national, ... Join the fight against antimicrobial resistance by pledging to use antibiotics responsibly and to promote awareness of ...
  http://www.wpro.who.int/topics/drug_resistance/en/
*  Transmitted HIV drug resistance in Asia
Surveillance for transmitted HIV drug resistance is essential to assessing the longer term sustainability and durability of ... Purpose of review: Surveillance for transmitted HIV drug resistance is essential to assessing the longer term sustainability ... However, MSM appear to be at higher risk of transmitted resistance and may benefit from enhanced resistance assessments and ... resistance has primarily been reported to be below WHO thresholds for moderate resistance (i.e. ,5%). However, studies have ...
  http://www.comminit.com/content/transmitted-hiv-drug-resistance-asia-1
*  Drug resistance deadlier than cancer by 2050: Study
... Catherine Boyle , @cboylecnbc Published 4:38 AM ET Thu, 11 Dec 2014 ... Its forecasts, based on research by RAND Europe and KPMG, suggest that drug resistance, which is estimated to have caused ... warned that the developing world would be hardest hit by growth in drug resistance. Countries in particular danger are likely ... "There can be no doubt now that antimicrobial resistance is one of the biggest (risks) that we, all of us, face," Nick Stern, ...
  https://www.cnbc.com/2014/12/11/drug-resistance-to-kill-more-than-cancer-by-2050-study.html
*  Scientists Warn About Malarial Drug Resistance
Malaria could be developing resistance to the most effective type of drug, according to the initial results of studies of ... Drug Toxicity. Drug toxicity is an adverse reaction of the body towards a drug that results as a side effect of a drug, ... Malaria could be developing resistance to the most effective type of drug, according to the initial results of studies of ... often containing small amounts of the real drug, is thought to be helping nurture resistance. Professor Nick Day, of the ...
  http://www.medindia.net/news/Scientists-Warn-About-Malarial-Drug-Resistance-52193-1.htm
*  Mutations and Drug Resistance | Frontiers Research Topic
Mutation in drug target is a critical mechanism that results in drug resistance. The aim of this topic is to highlight ... resulting in drug resistance. In general, resistant mutations in drug targets are derived from tissue specimen of the patients ... Thus, one way to overcome drug resistance is to develop AR inhibitors that are active against multiple AR mutants. In another ... There are several scenarios under which a mutation could lead to drug resistance. Mutations could reduce the binding affinity ...
  https://www.frontiersin.org/research-topics/2063/mutations-and-drug-resistance
*  Rising levels of HIV drug resistance | EurekAlert! Science News
... according to the largest meta-analysis to date on HIV drug resistance, led by researchers at UCL and the World Health ... HIV drug resistance is approaching and exceeding 10 percent in people living with HIV who are about to initiate or reinitiate ... In July 2017, WHO published a new HIV drug resistance report, based on drug resistance national surveys conducted in 11 ... "Many people develop drug resistance after being treated by antiretroviral drugs if they stop taking their medication - often ...
  https://eurekalert.org/pub_releases/2017-11/ucl-rlo112917.php
*  Drug resistance: WHO report 'serious lack of new antibiotics'
... from the WHO reveals that the current scope of new antibiotic development is far from what is needed to tackle drug resistance. ... Drug resistance 'could kill 10 million people annually'. A review suggests that drug resistance could kill 10 million people ... Spotlight on: MRSA / Drug Resistance. * Antibiotic resistance: how has it become a global threat to public health? ... Drug resistance, or antimicrobial resistance, arises when pathogens evolve to evade the harms of antimicrobial therapeutics, ...
  https://www.medicalnewstoday.com/articles/319493.php
*  Drug Resistance Threatens HIV Fight in Africa
Scientists found a 29% increase in drug resistance per year in East Africa,... Health News Summaries. , Newser ... HIV is developing a growing resistance to drugs in sub-Saharan Africa, and that has researchers worried, the BBC reports. ... We do expect to see drug resistance, and it's at around 10% in the UK and US. But here, we monitor people regularly,' says the ... Newser) - HIV is developing a growing resistance to drugs in sub-Saharan Africa, and that has researchers worried, the BBC ...
  http://www.newser.com/story/150610/drug-resistance-threatens-hiv-fight-in-africa.html
*  Finality? - Forum on HIV Drug Resistance - TheBody.com
... drug resistance is always undesirable and best avoided if possible -... ... Here are a few general truths about drug resistance and antiretroviral therapy (ART) to consider in answer to your questions ... drug resistance is not a black and white or all or none phenomenon, rather drug resistance includes 'grey' zones in which an ... Ask the Experts > Forum on HIV Drug Resistance > Q & A Finality?. Jan 4, 2008 When patients develop resistence to certain drugs ...
  http://www.thebody.com/Forums/AIDS/Resistance/Q189774.html?ic=4003
*  consequences - Forum on HIV Drug Resistance - TheBody.com
In general though, acquiring drug resistance means that the response to the drug or drugs to which... ... It depends on the level of drug resistance, which can be minor, major or somewhere in between. ... In general though, acquiring drug resistance means that the response to the drug or drugs to which your virus shows resistance ... Ask the Experts > Forum on HIV Drug Resistance > Q & A consequences. May 8, 2001 what are the consequences of drug resistance ...
  http://www.thebody.com/Forums/AIDS/Resistance/Current/Q23132.qna
*  Drugs - Forum on HIV Drug Resistance - TheBody.com
These tests are quite good at detecting transmitted drug resistance - this information may be used at any... ... These tests are quite good at detecting transmitted drug resistance - this information may be used at any time in the future ... Read More About HIV/AIDS Drug Resistance Browse Forums: <-- Select -->. Aging. Choosing Your Meds. En Español. In Italiano. ... Drugs. Jul 30, 2001 Hi Doctor, My partner was recently diagnosed HIV+ and his VL is 30K with a CD4 of 700. The doctor's do not ...
  http://www.thebody.com/Forums/AIDS/Resistance/Q53892.html
*  BLIP? - Forum on HIV Drug Resistance - TheBody.com
Ask the Experts > Forum on HIV Drug Resistance > Q & A BLIP?. Sep 6, 2002 Hi, I recently received my viral load test. After ... When these values are less than 200, they have not been shown to be associated with impending viral failure or drug resistance ... Read More About HIV/AIDS Drug Resistance Browse Forums: <-- Select -->. Aging. Choosing Your Meds. En Español. In Italiano. ... Could it be the beginning of resistance to my VIDEX/ZERiT/VIRACEPT combo? (I never had more than 3000 copies in my life but I ...
  http://www.thebody.com/Forums/AIDS/Resistance/Q141395.html