*  Utilization of HIV Drug Resistance Testing in Treatment Experienced Patients (UTILIZE Study) - Full Text View - ClinicalTrials...
Sexually Transmitted Diseases, Viral. Sexually Transmitted Diseases. Immunologic Deficiency Syndromes. Immune System Diseases. ... Utilization of HIV Drug Resistance Testing in Treatment Experienced Patients (UTILIZE Study). This study has been completed. ... Utilization of HIV Drug Resistance Testing in Treatment Experienced Patients (UTILIZE Study). ... The secondary objective was to examine clinicians' use of HIV drug resistance testing in treatment experienced patients ...
  https://clinicaltrials.gov/show/NCT00615563?order=351
*  STIs Significantly Increase Risk of Drug-resistant HIV Transmission ( A study of people newly diagnosed with ...)
Genotypic resistance testing was performed on blood samples from ...,STIs,Significantly,Increase,Risk,of,Drug-resistant,HIV, ... The transmission of antiretroviral drug-resistant HIV is also wel... This study presented last week at the Fourteenth ... The high prevalence of STIs in those with recent HIV infection and their effect in increasing viral shedding strongly supports ... Genotypic resistance testing was performed on blood samples from all individuals; 28 (15%) were found to have resistance ...
  http://www.bio-medicine.org/medicine-news/STIs-Significantly-Increase-Risk-of-Drug-resistant-HIV-Transmission-18932-1/
*  A Long Term Safety Study Of Lersivirine For The Treatment Of HIV-1 Infection In Subjects Who Have Completed Treatment With...
NRTI or NNRTI resistance mutations': nucleoside reverse transcriptase inhibitor or lersivirine-associated resistance-associated ... Drug: efavirenz Efavirenz 600 mg tablets PO taken once daily + tenofovir DF 300 mg/emtricitabine 200 mg tablets PO once daily ... Patients must have had a viral load less than 50 copies/mL at Week 84 of the parent protocol. ... Drug: lersivirine Lersivirine 500 mg tablets PO taken once daily + tenofovir DF 300 mg/emtricitabine 200 mg tablets PO once ...
  https://clinicaltrials.gov/show/NCT01254656?order=333
*  The Detection of Drug-Resistant HIV-1 in Taiwan - Full Text View - ClinicalTrials.gov
In the western countries, studies suggest that the prevalence of viral resistance to at least one antiretroviral drug ranges ... Drug resistance can be measured using either genotypic or phenotypic resistance assays. Genotypic assays detect mutations that ... and transmission of drug-resistant virus has been documented to be possible. The emergence of drug resistance in HIV has been ... The likelihood that a patient will acquire drug-resistant virus is related to the prevalence of drug resistance in the ...
  https://clinicaltrials.gov/show/NCT00690001?order=233
*  Hepatitis C virus drug resistance and immune-driven adaptations: relevance to new antiviral therapy. - Oxford Vaccine Group
Consideration of HCV viral adaptation in terms of drug resistance as well as host 'immune resistance' in the STAT-C treatment ... Here, the prevalence of drug resistance mutations relevant to 27 developmental STAT-C drugs, and the potential for drug and ... is limited by the presence of drug-specific viral resistance mutations within the targeted proteins. Genetic diversity within ... at known drug resistance sites. CONCLUSION: Drug and host immune responses are likely to provide powerful selection forces that ...
  https://www.ovg.ox.ac.uk/publications/27286
*  Viral Load and Resistance - Forum on HIV Drug Resistance - TheBody.com
I share your physicians desire to see your viral load less than 50, and while numbers like 60, 83 and 155 are more acceptable, ... Ask the Experts > Forum on HIV Drug Resistance > Q & A Viral Load and Resistance. Nov 22, 2002 Susan: I am having some issues ... Read More About HIV/AIDS Drug Resistance Browse Forums: <-- Select -->. Aging. Choosing Your Meds. En Español. In Italiano. ... assuming that you still have no drug resistance). I will agree however, that I also see people with these kinds of numbers and ...
  http://www.thebody.com/Forums/AIDS/Resistance/Q143045.html
*  Viral Load Is Not Going D own. - Forum on HIV Drug Resistance - TheBody.com
Many people who start on 2 drugs and continue on only 2 drugs for a period of time do... ... The persistence of a detectable viral load would suggest that your treatment regimen is not potent enough. ... Many people who start on 2 drugs and continue on only 2 drugs for a period of time do develop some degree of drug resistance ... Ask the Experts > Forum on HIV Drug Resistance > Q & A Viral Load Is Not Going D own.. Mar 23, 2002 I am under ART for last 2 ...
  http://www.thebody.com/Forums/AIDS/Resistance/Q133592.html?ic=4003
*  The role of the HIV-1 reverse transcriptase mutation H208Y to drug resistance and viral fitness - UCL Discovery
The role of the HIV-1 reverse transcriptase mutation H208Y to drug resistance and viral fitness. Doctoral thesis , UCL ( ... The role of the HIV-1 reverse transcriptase mutation H208Y to drug resistance and viral fitness ... The role of the HIV-1 reverse transcriptase mutation H208Y to drug resistance and viral fitness. ... Accessory mutations are thought to arise alongside major or primary drug resistance mutations in order to augment resistance, ...
  http://discovery.ucl.ac.uk/1207313/
*  Scientific paper 39 - Viral drug resistance - hVIVO
Scientific paper 39 - Viral drug resistance March 7, 2017 11:01 am Viral drug resistance ... Starting with an overview of the area, each chapter focuses on a particular target with sections on drug resistance in malaria ... Journal: Molecular Genetics of Drug Resistance, Harwood Academic Publishers, 1997, p 81-138 ... More effective antiviral drugs, vaccines and novel therapeutic drug classes at a faster pace. ...
  http://hvivo.com/scientific-paper-39-viral-drug-resistance/
*  Persistence of transmitted HIV-1 drug resistance mutations associated with fitness costs and viral genetic backgrounds -...
Persistence of transmitted HIV-1 drug resistance mutations associated with fitness costs and viral genetic backgrounds ... Transmitted drug resistance mutations (TDRM) can persist in the absence of drugs for considerable time. It is generally ... Transmitted drug resistance mutations (TDRM) can persist in the absence of drugs for considerable time. It is generally ... Persistence of transmitted HIV-1 drug resistance mutations associated with fitness costs and viral genetic backgrounds. PLoS ...
  http://www.zora.uzh.ch/id/eprint/114707/
*  HIV Macromolecular Interactions and Impact on Viral Evolution of Drug Resistance - Arthur Olson
HIV Macromolecular Interactions and Impact on Viral Evolution of Drug Resistance Olson, Arthur J. Scripps Research Institute, ... 2016) HIV-1 Integrase Binds the Viral RNA Genome and Is Essential during Virion Morphogenesis. Cell 166:1257-1268.e12 ...
  http://grantome.com/grant/NIH/P50-GM103368-03
*  HIV Macromolecular Interactions and Impact on Viral Evolution of Drug Resistance - Arthur Olson
HIV Macromolecular Interactions and Impact on Viral Evolution of Drug Resistance Olson, Arthur J. Scripps Research Institute, ... implications of viral macromolecular interactions and dynamics and its broader impacts of the evolution of drug resistance. The ... We will explore resistance evolution in HIV as an opportune platform upon which to characterize the dynamic relationships ... HIV enzymes with their partners and effectors since they encompass key processes in the viral life cycle and as existing drug ...
  http://grantome.com/grant/NIH/P50-GM103368-01
*  Lymphopenia is induced by lymphoablative therapies and chronic viral attacks. improved - Drug Resistance to EGFR Inhibitors in...
Lymphopenia is induced by lymphoablative therapies and chronic viral attacks. improved On January 6, 2018 by Freddie Garcia ... Lymphopenia is induced by lymphoablative therapies and chronic viral attacks. improved during allograft being rejected in CB ...
  http://elevateblogconference.com/lymphopenia-is-induced-by-lymphoablative-therapies-and-chronic-viral-attacks-improved/
*  Development of a platform for HIV/HCV genotyping to anti-viral drug resistance using Next Generation Sequencing - NGS...
1 Development of a platform for HIV/HCV genotyping to anti-viral drug resistance using Next Generation Sequencing - NGS ... Apresentação em tema: "Development of a platform for HIV/HCV genotyping to anti-viral drug resistance using Next Generation ... Carregar ppt "Development of a platform for HIV/HCV genotyping to anti-viral drug resistance using Next Generation Sequencing ... Development of a platform for HIV/HCV genotyping to anti-viral drug resistance using Next Generation Sequencing - NGS ...
  http://slideplayer.com.br/slide/1258643/
*  Therapeutic Drug Monitoring and Viral Resistance Testing in the Treatment of HIV-Infected Children - Full Text View -...
Therapeutic Drug Monitoring and Viral Resistance Testing in the Treatment of HIV-Infected Children. The safety and scientific ... Therapeutic Drug Monitoring and Viral Resistance Testing in the Treatment of HIV-Infected Children. ... If not enough of the drug is found in the blood, the dose of the drug will be increased and the amount of the drug in the blood ... monitoring drug blood levels to make sure there is enough drug to work against the virus, and changing the drug dose if it is ...
  https://clinicaltrials.gov/show/NCT00032669?order=153
*  A Study to Demonstrate That Anti-HIV Drug Therapy Can be Stopped Without Causing Viral Resistance, and to Characterize Drug...
Drug Administration Schedule. Drug Resistance, Microbial. Genotype. Reverse Transcriptase Inhibitors. Anti-HIV Agents. Viral ... A Study to Demonstrate That Anti-HIV Drug Therapy Can be Stopped Without Causing Viral Resistance, and to Characterize Drug ... The purpose of this study is to find out if anti-HIV drugs can be stopped without the virus becoming resistant to the drugs. ... an anti-HIV drug that remains in the body longer than most treatment drugs. In another study, patients were treated with EFV, ...
  https://clinicaltrials.gov/show/NCT00029341?order=531
*  Estimating the Incidence of HIV Infection Among Men Who Have Sex With Men in Peru and Ecuador - Full Text View - ClinicalTrials...
Drug resistance, viral. Additional relevant MeSH terms: Infection. HIV Infections. Acquired Immunodeficiency Syndrome. Sexually ... Broad access to ARVs in countries without regular drug resistance testing can also cause rapid development of ARV resistance. ... Antiretroviral drug resistance testing in adults infected with human immunodeficiency virus type 1: 2003 recommendations of an ... patterns of HIV resistance, and genetic variability of viral strains, Peru and Ecuador will be better equipped to monitor the ...
  https://clinicaltrials.gov/show/NCT00279331?order=270
*  Treatment of Hepatitis in Patients Who Are Triple-Infected With HIV, Hepatitis B Virus (HBV), and Hepatitis C Virus (HCV) -...
Drug Resistance, Viral. Treatment Experienced. Additional relevant MeSH terms: Hepatitis. Hepatitis A. Hepatitis C. HIV ... Drug: Adefovir dipivoxil Drug: Peginterferon-alfa-2A Drug: Ribavirin Procedure: Liver Biopsy Phase 2 ... Mutations in hepatitis B DNA polymerase associated with resistance to lamivudine do not confer resistance to adefovir in vitro ... Hepatitis, Viral, Human. Virus Diseases. Enterovirus Infections. Picornaviridae Infections. RNA Virus Infections. Flaviviridae ...
  https://clinicaltrials.gov/show/NCT00051077?order=320
*  EP 1012334 A1 20000628 - COMPOSITIONS AND METHODS FOR DETERMINING ANTI-VIRAL DRUG SUSCEPTIBILITY AND RESISTANCE AND ANTI-VIRAL...
... determining anti-viral drug susceptibility of the same patient at a later time; and (c) comparing the anti-viral drug ... determining anti-viral drug susceptibility of the same patient at a later time; and (c) comparing the anti-viral drug ... are carried out in the absence of the anti-viral drug, wherein a test concentration of the anti-viral drug is present at steps ... are carried out in the absence of the anti-viral drug, wherein a test concentration of the anti-viral drug is present at steps ...
  https://data.epo.org/gpi/EP1012334A1-COMPOSITIONS-AND-METHODS-FOR-DETERMINING-ANTI-VIRAL-DRUG-SUSCEPTIBILITY-AND-RESISTANCE-AND-ANTI-VIRAL-DRUG-SCREENING
*  Three Generic Nevirapine-Based Antiretroviral Treatments in Chinese Patients:Multicentric Observation Cohort - Full Text View -...
Drug Resistance, Viral. treatment naïve. Additional relevant MeSH terms: HIV Infections. Lentivirus Infections. Retroviridae ... Drug: Zidovudine (AZT)+ Didanosine (ddI)+ Nevirapine (NVP) Drug: Stavudine (d4T), Lamivudine (3TC), Nevirapine (NVP) Drug: ... Drug: Stavudine (d4T), Lamivudine (3TC), Nevirapine (NVP) Stavudine (d4T) 30mg bid (W,60Kg)20mg bid (W,60Kg) Lamivudine (3TC) ... Drug: Zidovudine (AZT)+ Didanosine (ddI)+ Nevirapine (NVP) Zidovudine (AZT) 300mg bid Didanosine (ddI) 200mg bid (W,60Kg)125mg ...
  https://clinicaltrials.gov/show/NCT00618176?order=387
*  Discovery and development of NS5A inhibitors - Wikipedia
... often associated with amino acid substitutions that confer upon the virus a robust drug resistance without impairing the viral ... The potential HCV resistance against DAA drugs is a concern. Among the HCV quasispecies there are pre-existing variants with ... Recently, the central role of NS5A in viral proliferation has made it the target for drug development. As a result, new ... Shorter therapies with milder side effects would yield greater adherence, and the ever present spectre of drug resistance is ...
  https://en.wikipedia.org/wiki/Discovery_and_development_of_NS5A_inhibitors
*  Antiviral Therapy (journal) - Wikipedia
... drug resistance, viral diagnostics, drug safety, pharmacoepidemiology, and vaccines. Antiviral Therapy is an official ... including the International HIV Drug Resistance Workshop, International Workshop on Adverse Drug Reactions and Lipodystrophy in ... It publishes primary papers and reviews on all aspects of the clinical development of antiviral drugs, including clinical trial ... HIV, and the Therapies for Viral Hepatitis Workshop. Articles from 1998 are archived online in PDF format, with content over a ...
  https://en.wikipedia.org/wiki/Antiviral_Therapy_(journal)
*  David M. Knipe - Wikipedia
This methodology was used to map viral glycoproteins, plaque morphology, and drug resistance markers, and to construct a ... He defined the structure of viral chromatin during latent infection of neurons and the mechanisms by which viral DNA is kept ... Orzalli, Megan H.; Knipe, David M. (2014). "Cellular Sensing of Viral DNA and Viral Evasion Mechanisms". Annual Review of ... to the viral replication compartments and that some of these inhibit viral replication while some are essential for viral ...
  https://en.wikipedia.org/wiki/David_M._Knipe
*  Viral phylodynamics - Wikipedia
Antiviral treatment also creates selective pressure for the evolution of drug resistance in virus populations, and can thereby ... Sequencing of virus from newly diagnosed patients is now routine in many countries for surveillance of drug resistance ... Patterns of viral genetic variation will also be affected by selection acting on viral phenotypes. Although viruses can differ ... Due to the impact that transmission dynamics and selection can have on viral genetic variation, viral phylogenies can therefore ...
  https://en.wikipedia.org/wiki/Viral_phylodynamics
*  Human cytomegalovirus - Wikipedia
Major risk factors for HCMV drug resistance are the residual capacity of the host's immune system to control viral replication ... HCMV antiviral drug resistance can be detected by phenotypic or by genotypic drug resistance testing. Phenotypic resistance ... "A new tool linking human cytomegalovirus drug resistance mutations to resistance phenotypes". Antiviral Research. 85 (2): 318- ... of amino acid changes in the UL97 protein kinase and the viral DNA polymerase have been reported to cause drug resistance. ...
  https://en.wikipedia.org/wiki/Human_cytomegalovirus