*  Drug-resistance Fears for Deadly Fungal Disease - Healthcanal.com : Healthcanal.com
... the class of drugs used to treat patients with aspergillosis. "This innovative approach to drug resistance detection was made ... UCL Home UCL News Drug-resistant gene goes from pig farms to pati… Drug-resistant gene goes from pig farms to patients ... High frequency triazole resistance found in non-culturable Aspergillus fumigatus from lungs of patients with chronic fungal ... Drug reduces inflammation in stroke patients 03/26/2018 Stroke Large-scale genetic study provides new insight into the causes ...
  https://www.healthcanal.com/infections/16998-drug-resistance-fears-for-deadly-fungal-disease.html
*  Millions at risk as deadly fungal infections acquire drug resistance - Infinite Unknown
Millions at risk as deadly fungal infections acquire drug resistance. August 28, 2016. August 28, 2016. by Infinite ... Millions at risk as deadly fungal infections acquire drug resistance:. Researchers believe widespread use of fungicides on ... Researchers say the widespread use of fungicides on crops is one of the main causes of the rise in fungal resistance, which ... A vaccine that could protect against fungal disease has yet to be developed, while the rise of resistance to the class of ...
  https://infiniteunknown.net/2016/08/28/millions-at-risk-as-deadly-fungal-infections-acquire-drug-resistance/
*  Pharmaceuticals | Free Full-Text | Pathogenesis and Antifungal Drug Resistance of the Human Fungal Pathogen Candida glabrata
In this comprehensive review, we want to emphasize and discuss the mechanisms underlying virulence and drug resistance of C. ... glabrata infections is its high intrinsic resistance to several antifungal drugs, especially azoles. Further, the development ... represents the second most prevalent cause of candidemia and a better understanding of its virulence and drug resistance ... of antifungal resistance, particularly during prolonged and prophylactic therapies is diminishing efficacies of therapeutic ...
  http://mdpi.com/1424-8247/4/1/169/xml
*  Cas5 Couples Stress Responses, Drug Resistance and Cell Cycle Regulation in Fungal Pathogens | Nature Research Microbiology...
Cas5 Couples Stress Responses, Drug Resistance and Cell Cycle Regulation in Fungal Pathogens Poster image is a time-lapse ... Shapiro, R. S., N. Robbins and L. E. Cowen (2011). "Regulatory circuitry governing fungal development, drug resistance, and ... 2011). Given that drug resistant fungal infections are plaguing clinical settings, it is now critical to uncover novel cellular ... 2006), but is required for drug resistance and virulence in C. albicans (Chamilos, Nobile et al. 2009, Pukkila-Worley, Peleg et ...
  https://naturemicrobiologycommunity.nature.com/posts/20197-cas5-couples-stress-responses-drug-resistance-and-cell-cycle-regulation-in-fungal-pathogens
*  Medical Xpress - chronic obstructive pulmonary disease(... continued page 10)
Drug resistance fears over killer fungal disease. (PhysOrg.com) -- Treatments for the most common airborne fungal disease are ... proving less effective due to increased resistance to the anti-fungal drugs used to combat infections. ... Previously unpublished information from the clinical trial that the U.S. Food and Drug Administration relied on to approve the ... For older adults with chronic conditions, non-drug behavioral treatments may help. When we have several chronic health ...
  https://medicalxpress.com/conditions/chronic-obstructive-pulmonary-disease/page10.html
*  Fluconazole Archives - Progressive Radio Network
Millions at risk as deadly fungal infections acquire drug resistance Scientists have warned that potentially deadly fungal ... Combination therapyDeathDrug resistanceFluconazoleFungusInfectionMultiple organ dysfunction syndromeMycosisPittsburgh Tribune- ... More than a million people die of fungal infections every year, including about 7,000 in the UK, and deaths are likely to ... increase as resistance continues to rise. Researchers say the widespread use of fungicides on crops is one … Read More ...
  http://prn.fm/tag/fluconazole/
*  Structural and Functional Study of Yer067w, a New Protein Involved in Yeast Metabolism Control and Drug Resistance
Stress, drugs, and evolution: The role of cellular signaling in fungal drug resistance. Eukaryot Cell. 2008;7:747-764. [PMC ... Therefore, the characterization of new fungal-specific proteins involved in the development of drug resistance is of ... As both classes of drugs act on components of the same pathway, the mechanisms of resistance developed against one kind of drug ... No differences in drug resistance between BY4741 and the mutants were evident when yeast cells were grown in the presence of ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2887356/
*  Baker's Yeast Leads Biologists to Understand Drug Resistance in Fungi
Biologists at Lomonosov Moscow State University advanced in understanding of fungal drug resistance mechanisms. ... Baker's Yeast Leads Biologists to Understand Drug Resistance in Fungi. Wed, 07/11/2018 - 8:00am Comments by Lomonosov Moscow ... Drug resistance of pathogenic microorganisms is a serious medical problem. The most widely known threat is antibiotic-resistant ... In 2016 a team from Belozersky Institute of Physico- Chemical Biology proposed a method of suppressing multiple drug resistance ...
  https://www.laboratoryequipment.com/news/2018/07/bakers-yeast-leads-biologists-understand-drug-resistance-fungi
*  Polyenes | definition of Polyenes by Medical dictionary
Fungal Biofilms and drug resistance. As a class, the echinocandins possess a mechanism of action that is distinct from those of ... The polyenes cause the fungal cell to die by intercalating into ergosterol-containing membranes, the major sterol in fungal ... Antifungal drugs (azoles, pyrimidines, echinodians, polyenes, allylamines, and other antifungal drugs). Global Infectious ... Polyenes bind directly to the unique fungal sterol ergosterol and compromise membrane function.. Ocular mycoses: infection of ...
  http://medical-dictionary.thefreedictionary.com/Polyenes
*  Northern blot analysis | Article about Northern blot analysis by The Free Dictionary
Fungal Biofilms and drug resistance. We have not quantified the response by DD RT-PCR and Northern blot analysis compared with ...
  https://encyclopedia2.thefreedictionary.com/Northern+blot+analysis
*  Infections Blog Sites - Blog Top Sites
She also explains.. the ever rising anti-fungal drug resistance.. Owner: ssdhospital ... With the onset of the rainy season, there is a rise in fungal infections on our skin. In this.. column, Dr Sneh Thadani ... explains the reasons and prevention for fungal infections. ...
  http://www.blogtopsites.com/tag/infections
*  Molecules | Free Full-Text | Anti-Candida Activity of Bursera morelensis Ramirez Essential Oil and Two Compounds, α-Pinene and...
The abuse of antifungals has contributed to the development of resistance. B. morelensis has demonstrated antibacterial and ... Tscherner, M.; Schwarzmüller, T.; Kuchler, K. Pathogenesis and antifungal drug resistance of the human fungal pathogen Candida ... Fungal Biol. 2010, 114, 189-197. [Google Scholar] [CrossRef] [PubMed]. *Liesche, J.; Marek, M.; Günther-Pomorski, T. Cell wall ... Fungal Genet. Biol. 1999, 28, 135-145. [Google Scholar] [CrossRef] [PubMed]. *Gale, C.; Gerami-Nejad, M.; McClellan, M.; ...
  http://www.mdpi.com/1420-3049/22/12/2095/htm
*  Annelise E. Barron | Stanford Medicine Profiles
Consequently, there is a pressing need to develop new drugs that circumvent fungal drug-resistance mechanisms. In this work we ... including synthetic polypeptoid drag-tags as well as genetically engineered protein polymer drag-tags. The enhanced drag ... The additional drag of the charge-neutral drag-tag breaks the linear scaling of the charge-to-friction ratio of DNA and enables ... Drag was found to scale linearly with total molecular weight, regardless of branch length. The octamer-branched drag-tag-DNA ...
  https://med.stanford.edu/profiles/annelise-barron
*  Antimicrobial peptide-metal ion interactions - a potential way of activity enhancement - New Journal of Chemistry (RSC...
Because of a general lack of resistance towards antimicrobial peptides (AMPs), they are being relied on as a novel class of ... therapeutics aiming to conquer drug-resistant bacteria and fungi. Ther ... Increasing bacterial and fungal drug resistance requires novel, effective antimicrobial treatments to be actively sought. ... Increasing bacterial and fungal drug resistance requires novel, effective antimicrobial treatments to be actively sought. ...
  http://pubs.rsc.org/en/content/articlelanding/2018/nj/c7nj04709f
*  Candida albicans - Wikipedia
Shapiro, R. S.; Robbins, N.; Cowen, L. E. (2011). "Regulatory Circuitry Governing Fungal Development, Drug Resistance, and ... Small intestinal fungal overgrowth (SIFO) is characterized by the presence of excessive number of fungal organisms in the small ... The most used selection markers in C. albicans are the CaNAT1 resistance marker (confers resistance against nourseothricin) and ... www.cdc.gov/fungal/antifungal-resistance.html Sellama A, Whiteway M (2016). "Recent advances on Candida albicans biology and ...
  https://en.wikipedia.org/wiki/Candida_albicans
*  Official ESCRS | European Society of Cataract & Refractive Surgeons
Up-regulation of multi-drug resistance transporter genes was found common to the selected fungal isolates (MDR1, MDR2, MDR4 and ... Regulation of genes play a significant role in determining drug resistance pattern of fungal biofilm formation. Financial ... a collection of fungal clinical isolates were analyzed for the known molecular mechanisms of resistance. Fungal isolates were ... This study analyzed the selected genes responsible for antifungal resistance in fungal pathogens like Aspergillus fumigatus, ...
  http://www.escrs.org/Copenhagen2016/programme/free-papers-details.asp?id=26937&day=0
*  SHIFT Daily News | SHIFT Daily News | Russia finance chief says crypto currencies are a fact of life
Fungal Drug Resistance - What to do about it. Even when you think you are safe inside the sanitized hospital walls, fungus can ...
  http://shiftdailynews.com/author/Sean/page/3/
*  2015 Fungal Genetics Conference
... drug resistance in fungal disease. Paul Bowyer. 5:00. Succinate-dehydrogenase inhibitors (SDHIs) resistance evolution in cereal ... Fungal cell wall remodelling and antifungal drug tolerance. Carol Munro. 3:20. RNA-seq analysis of Cercospora beticola DMI- ... Fungal Volatiles: Critical Signals for Fungal Interactions Co-chairs: Joan Bennett and Seogchan Kang. 3:00. Volatile Organic ... Tracing the evolutionary trajectory of drug resistance and virulence in clinical isolates of Candida albicans. Dawn Thompson. 4 ...
  http://www.genetics-gsa.org/fungal/2015/pages/sessionlisting.shtml
*  Antifungal mechanism of the combination of Cinnamomum verum and Pelargonium graveolens essential oils with fluconazole against...
Antifungal drug resistance mechanisms in fungal pathogens from the perspective of transcriptional gene regulation ... However, P. graveolens EO may disturb the permeability barrier of the fungal cell wall. An increase of MIC values of P. ... Anti-candidal activity of essential oils alone and in combination with amphotericin B or fluconazole against multi-drug ... Antifungal activity of essential oils and their synergy with fluconazole against drug-resistant strains of Aspergillus ...
  https://www.deepdyve.com/lp/springer_journal/antifungal-mechanism-of-the-combination-of-cinnamomum-verum-and-gH8Wa2ujqC
*  Onychomycosis (Tinea unguium, Nail fungal infection) - ONA
Visit us often for drug therapy testing results, patient care information and more. Download our FREE app today. ... Although fungal drug resistance is not a problem in the treatment of dermatophyte onychomycosis, Candida species such as C. ... There is no evidence that fungal drug resistance is important in treatment of dermatophyte onychomycosis. Therefore, a systemic ... Fungal infection drug for lung transplant recipients may increase cancer, death risk ...
  https://www.oncologynurseadvisor.com/dermatology/onychomycosis-tinea-unguium-nail-fungal-infection/article/590412/
*  Faculty Scholars Program | HHMI.org
Her research may lead to therapies that counter the evolution of drug resistance in fungal and bacterial pathogens, viruses, ... with the ultimate goal of overcoming resistance to conventional drug-treatment. ... She is also developing research tools that will enable her to measure membrane tension in live cells and to explore electrical ... Better understanding of this nearly impermeable barrier could make it easier to deliver drugs to the brain. She is also ...
  http://www.hhmi.org/programs/biomedical-research/faculty-scholars
*  RISE PhD | Participants
Jesus' research interests are Fungal Biofilms, Drug Resistance, Drug Discovery, Drug Repurposing, Microbial Pathogenesis, ... The lab specializes in drug discovery and development, fungal biology of the opportunistic pathogen Candida albicans, and ...
  http://www.utsa.edu/mbrs/phdRISE/bio/JesusRomo.htm
*  ASMscience | |span class='jp-italic'|Aspergillus|/span| Biofilm |span class='jp-italic'|In Vitro|/span| and |span class='jp...
... since biofilm formation poses an important clinical problem due to their resistance to antifungal agents. Furthermore, in vivo ... and drug resistance. However, most data on A. fumigatus biofilms have been obtained in vitro and should be confirmed using in ... Hsp90 governs dispersion and drug resistance of fungal biofilms. PLoS Pathog 7:e1002257. doi:10.1371/journal.ppat.1002257. [ ... Biofilms and their role in the resistance of pathogenic Candida to antifungal agents. Curr Drug Targets 7:465-470. [PubMed][ ...
  http://www.asmscience.org/content/journal/microbiolspec/10.1128/microbiolspec.MB-0017-2015
*  ASMscience | Fungal Biofilms: |span class='jp-italic'|In Vivo|/span| Models for Discovery of Anti-Biofilm Drugs
... and fluid dynamics of clinical niches and have been instrumental in the study of drug resistance and investigation of novel ... Therefore, the discovery of novel compounds and innovative strategies to treat fungal biofilms is of great interest. Although ... This chapter describes the significance of fungal biofilm infections, the animal models developed for biofilm study, and how ... these models have contributed to the development of new strategies for the eradication of fungal biofilm infections. ...
  http://www.asmscience.org/content/journal/microbiolspec/10.1128/microbiolspec.MB-0008-2014
*  Frontiers | Sporothrix schenckii sensu stricto and Sporothrix brasiliensis Are Differentially Recognized by Human Peripheral...
2012a). Host carbon sources modulate cell wall architecture, drug resistance and virulence in a fungal pathogen. Cell Microbiol ... Role of the fungal cell wall in pathogenesis and antifungal resistance. Curr. Fungal Infect. Rep. 6, 275-282. doi: 10.1007/ ... source-induced reprogramming of the cell wall proteome and secretome modulates the adherence and drug resistance of the fungal ... In fungal species such as C. albicans, A. fumigatus, Histoplasma capsulatum, and Paracoccidioides brasiliensis, it has been ...
  https://www.frontiersin.org/articles/10.3389/fmicb.2017.00843/full