Loading...
*  Species Differences in Somatodendritic Dopamine Transmission Determine D2-Autoreceptor-Mediated Inhibition of Ventral Tegmental...
All drugs except dopamine were applied by bath perfusion. Dopamine was applied by iontophoresis. Dopamine (1 m) was ejected as ... Dopamine transporter regulation of extracellular dopamine in the VTA. Dopamine transporters regulate the amplitude and duration ... 1E). Likewise the τdecay of D2-IPSCs was slower in dopamine cells from the guinea pig VTA than in dopamine cells from rat or ... Dopamine D2-IPSCs were significantly slower in the guinea pig. In guinea pig dopamine cells, IPSCs had a slower rise time, time ...
  http://www.jneurosci.org/content/32/39/13520
*  Modelling drug abuse potential with positron emission tomography of the dopaminergic system
... by blocking reuptake by binding to the dopamine transporter or by indirectly increasing dopamine via interactions with other ... This increase in dopamine is necessary, but not sufficient to produce reinforcing effects such as a feeling of 'high'. ... The neurotransmitter dopamine plays an important role in modulating reinforcing effects in the reward circuitry of the brain. ... We first briefly outline the theories of the establishment of addiction in humans and the role of dopamine in the brain's ...
  https://dspace.library.uu.nl/handle/1874/33694
*  Control of Extracellular Dopamine at Dendrite and Axon Terminals | Journal of Neuroscience
Extracellular dextran slows the free diffusion of dopamine. FSCV measurement of free dopamine in solution. Dopamine was applied ... Dopamine neurons were identified by the presence of a D2-sensitive dopamine IPSC and pacemaker (1-5 Hz) firing with spikes ... Dopamine IPSCs in the VTA and SNc are similar despite a greater extracellular presence of dopamine in the VTA. Example traces ... Dopamine release in the VTA, SNc, and striatum exhibit similar dependences upon extracellular calcium. A-C, Dopamine release in ...
  http://www.jneurosci.org/content/30/20/6975?ijkey=7be8a9fb30cd250679998f419455004728ecd30c&keytype2=tf_ipsecsha
*  Feeding increases dopamine metabolism in the rat brain | Science
These results indicate that the release of dopamine from particular groups of central neurons is increased during feeding and ... Feeding induced by food deprivation is accompanied by an increased production of the dopamine metabolite 3,4- ...
  http://science.sciencemag.org/content/208/4448/1168
*  HETEROLOGOUS MONOAMINE REUPTAKE - LACK OF TRANSMITTER SPECIFICITY OF NEURON-SPECIFIC CARRIERS | IRIS Univ. Cagliari
... an inhibitor of the dopamine (DA) reuptake carrier, on the in vivo extracellular concentrations of dopamine (DA) was studied by ... an inhibitor of the dopamine (DA) reuptake carrier, on the in vivo extracellular concentrations of dopamine (DA) was studied by ...
  https://iris.unica.it/handle/11584/94801
*  D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons | Science
Severe movement disorders result from the loss of striatal dopamine in patients with Parkinson's disease. Rats with lesions of ... D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons ... D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons ... D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons ...
  http://science.sciencemag.org/content/250/4986/1429
*  Two Dopamine Receptors Are Key to Ritalin Activity | www.bioquicknews.com
Two Dopamine Receptors Are Key to Ritalin Activity. Mon, 03/08/2010 - 22:00 - bioquicknews Research reported by scientists from ... "We found that a dopamine receptor, known as the D2 receptor, controls the ability to stay focused on a task--the well-known ... However, they also found that if they blocked the dopamine D1 receptors with drugs, Ritalin was unable to enhance learning. And ... "But we also discovered that another dopamine receptor, D1, underlies learning efficiency." "Since we now know that Ritalin ...
  http://www.bioquicknews.com/node/289
*  Reduced Vesicular Storage of Dopamine Causes Progressive Nigrostriatal Neurodegeneration | Journal of Neuroscience
D , HPLC analysis of striatal dopamine levels of 2-month-old VMAT2 WT, HT, and LO mice. E , HPLC analysis of striatal dopamine ... Mishandling of dopamine has been suggested to participate in the dopamine neurodegeneration that underlies PD (Graham, 1978; ... 1 E). These reductions are accompanied by an increase in the ratios of dopamine metabolites to dopamine in the aged VMAT2 LO ... 1996) Modification of dopamine transporter function: effect of reactive oxygen species and dopamine. J Neurochem 67:593-600. ...
  http://www.jneurosci.org/content/27/30/8138
*  The effects of benzofury (5-APB) on the dopamine transporter and 5-HT2-dependent vasoconstriction in the rat - CLOK - Central...
These data show that 5-APB interacts with the dopamine transporter and is an agonist at the 5-HT2A and 5-HT2B receptors in the ... The effects of benzofury (5-APB) on the dopamine transporter and 5-HT2-dependent vasoconstriction in the rat ... ORCID: 0000-0002-8180-7943 (2014) The effects of benzofury (5-APB) on the dopamine transporter and 5-HT2-dependent ... We hypothesized that 5-APB would activate the dopamine and 5-HT systems which may underlie its putative stimulant and ...
  http://clok.uclan.ac.uk/18222/
*  Leicester Research Archive: Modelling ischaemia in vitro: Effects of temperature and glucose concentration on dopamine release...
Modelling ischaemia in vitro: Effects of temperature and glucose concentration on dopamine release evoked by oxygen and glucose ...
  https://lra.le.ac.uk/handle/2381/11276
*  Effects of phencyclidine, amphetamine and related compounds on dopamine release from and uptake into striatal synaptosomes. |...
... dopamine displacement by unlabeled dopamine ([1H]dopamine). The displacement of [3H]dopamine by 10(-7) M [1H]dopamine was ... dopamine. The concentrations of reserpine required to inhibit [3H]dopamine uptake and [3H]dopamine displacement by [1H]dopamine ... dopamine, PCP was less potent than nomifensine or benztropine in inhibiting [3H]-dopamine displacement by 10(-7) M [1H]dopamine ... These results indicate that PCP is less potent than amphetamine at releasing dopamine and may affect dopamine metabolism in the ...
  http://jpet.aspetjournals.org/content/229/3/671.long
*  Faculty Research in Neurotoxicology | Department Website
Dopamine signaling is conserved across all animal species and has been implicated in the disease process of many neurological ... Increasing evidence suggests that the neurotransmitter dopamine may have a neurotoxic metabolic product (DOPAL) that ... using a transgenic strain of zebrafish with fluorescent labeling of cells that express the dopamine transporter. The pretectum ... an anatomical region of the brain implicated in dopamine production and voluntary motor control. ...
  https://www2.humboldt.edu/psychology/story/faculty-research-neurotoxicology
*  Pain and Depression: A Neurobiological Perspective of Their Relationship
Fian and Smith63 have also proposed that the homeostatic regulation of tonic and phasic dopamine may contribute to both pain ... Hence, attention to the role of dopamine in pain and depression would help clinicians understand both clinical conditions more ... Pain-related depression of the mesolimbic dopamine system in rats: expression, blockade by analgesics, and role of endogenous k ... In a study with pramipexole, a dopamine receptor agonist, for the treatment of fibromyalgia, the primary outcome was ...
  http://psychiatryinvestigation.org/journal/view.php?number=144
*  Tamoxifen Diminishes Methamphetamine-Induced Striatal Dopamine Depletion in Intact Female and Male Mice - Dluzen - 2001 -...
The dihydroxyphenylacetic acid/dopamine ratios following MA for female and male mice treated with TMX or females treated with ... J. Ji, J. L. McDermott, D. E. Dluzen, Sex Differences in K+-Evoked Striatal Dopamine Output from Superfused Striatal Tissue ... Striatal dopamine concentrations of TMX-treated female and male mice receiving MA were significantly greater than mice ... Mélanie Bourque, Bin Liu, Dean E. Dluzen, Thérèse Di Paolo, Tamoxifen protects male mice nigrostriatal dopamine against ...
  http://onlinelibrary.wiley.com/doi/10.1046/j.1365-2826.2001.00675.x/full?globalMessage=0
*  Pro-Leu-GlyNH2 affects dopamine and noradrenaline utilization in rat limbic-forebrain nuclei
The effects of PLG on dopamine disappearance are comparable to those previously found with vasopressin, while the effects of ... Pro-Leu-GlyNH2 affects dopamine and noradrenaline utilization in rat limbic-forebrain nuclei. DSpace/Manakin Repository. ... PLG, dose-dependently, increased dopamine disappearance in the nucleus caudatus and globus pallidus, whereas a decrease in ... dopamine disappearance was observed in ... read more the nucleus dorsomedialis. Noradrenaline disappearance was decreased in ...
  https://dspace.library.uu.nl/handle/1874/17420
*  Dopamine receptor - Wikipedia
Category:Dopamine antagonists. References[edit]. *^ Girault JA, Greengard P (2004). "The neurobiology of dopamine signaling". ... The neurotransmitter dopamine is the primary endogenous ligand for dopamine receptors. Dopamine receptors are implicated in ... D3 is encoded by the Dopamine receptor D3 gene (DRD3). Maximum expression of dopamine D3 receptors is noted in the islands of ... Dopamine receptor D1 and Dopamine receptor D5 are Gs coupled receptors that stimulate adenylyl cyclase to produce cAMP, ...
  https://en.wikipedia.org/wiki/Dopamine_receptor
*  Dopamine deficiency: Symptoms, causes, and treatment
A dopamine deficiency is linked to several health conditions, including Parkinson's disease and depression. Learn more about ... A dopamine deficiency can be due to a drop in the amount of dopamine made by the body or a problem with the receptors in the ... Dopamine vs. serotonin. Dopamine and serotonin are both naturally occurring chemicals in the body that have roles in a person's ... Drug abusers have also been shown to have significant decreases in dopamine D2 receptors and dopamine release. ...
  https://www.medicalnewstoday.com/articles/320637.php
*  dopamine - Wiktionary
dopamine (countable and uncountable, plural dopamines). *(biochemistry) A neurotransmitter associated with movement, attention ... Retrieved from "https://en.wiktionary.org/w/index.php?title=dopamine&oldid=47531834" ...
  https://en.wiktionary.org/wiki/dopamine
*  Dopamine
... everything you need for studying or teaching Dopamine. ... Immediately download the Dopamine summary, chapter-by-chapter ... Dopamine Dopamine (DA) is a catecholamine according to its chemical structure and a neurotransmitter of special importance for ... Dopamine Dopamine is one of a class of neurotransmitters known as catecholamines. A neurotransmitter is a chemical messenger ...
  http://www.bookrags.com/Dopamine/
*  Salamander Dopamine - Subcortical Brain
Salamander Dopamine Cross references: Dopamine Dopamine Receptors Tyrosine Hydroxylase Salamander Brain of the Tiger Salamander ... Searching for "salamander dopamine" yielded: PubMed = 66 http://www.ncbi.nlm.nih.gov/pubmed/?term=salamander+dopamine Google = ... In both species, dopamine-immunoreactive (DAi) cell bodies were observed in the olfactory bulb, the preoptic area, the ... Comparative analysis of dopamine and tyrosine hydroxylase immunoreactivities in the brain of two amphibians, the anuran Rana ...
  https://sites.google.com/site/subcorticalbrain/home/salamander-dopamine
*  Sticky dopamine - Neurophilosophy
But the dopamine-based glue has many potenital applications, including the formation copper nitrate-coated sheets for use in ... Now, writing in the journal Science, Messersmith's team reports that they have used dopamine itself to form a highly adhesive ... In these conditions, the dopamine molecules bind to each other end-to-end to form chain-like molecules. (These chains are ... Messersmith and his colleagues first added dopamine to water that had the same pH (acidity) as seawater. ...
  http://scienceblogs.com/neurophilosophy/2007/10/19/sticky-dopamine/
*  Dopamine receptor D4 - Wikipedia
dopamine binding. • drug binding. • dopamine neurotransmitter receptor activity, coupled via Gi/Go. • epinephrine binding. • ... positive regulation of dopamine uptake involved in synaptic transmission. • signal transduction. • fear response. • dopamine ... regulation of dopamine metabolic process. • response to histamine. • behavioral fear response. • dopamine receptor signaling ... As with other dopamine receptor subtypes, the D4 receptor is activated by the neurotransmitter dopamine. It is linked to many ...
  https://en.wikipedia.org/wiki/Dopamine_D4_receptor
*  Dopamine hydrochloride
... is a type of medicine called a sympathomimetic inotrope. It is used in medical emergencies to increase ... Dopamine works by acting on dopamine receptors in the kidney, gut, brain and heart causing the blood vessels in these organs to ... Dopamine hydrochloride. Dopamine hydrochloride is a type of medicine called a sympathomimetic inotrope. It is used in medical ... Dopamine increases the strength of the heartbeat and improves blood flow to the tissues and organs in the body. It is used in ...
  https://www.netdoctor.co.uk/medicines/heart-blood/a6608/dopamine-hydrochloride/
*  dopamine (CHEBI:18243)
... dopamine (CHEBI:18243). dopamine 3-O-sulfate (CHEBI:37946) has functional parent dopamine (CHEBI:18243). dopamine 4-O-sulfate ( ... N-palmitoyl dopamine (CHEBI:134058) has functional parent dopamine (CHEBI:18243). Arachidonoyl dopamine (CHEBI:31231) has ... dopamine (CHEBI:18243) has role β-adrenergic agonist (CHEBI:35522) dopamine (CHEBI:18243) has role Escherichia coli metabolite ... dopamine (CHEBI:18243) has role human metabolite (CHEBI:77746) dopamine (CHEBI:18243) has role mouse metabolite (CHEBI:75771) ...
  https://www.ebi.ac.uk/chebi/searchId.do?chebiId=43686
*  CNS Dopamine Receptors | SpringerLink
The past 20 years has seen our appreciation of the function of dopamine in the brain elevated from that of a precursor for ... Dopamine Receptor Adenylate Cyclase Dopamine Agonist Guanine Nucleotide Adenylate Cyclase Activity These keywords were added by ... Bacopoulos, N. B., 1981, Acute Changes In The State Of Dopamine Receptors: in vitro monitoring with [3H]dopamine, Life Sci. 29 ... Komiskey, H. L., Bossart, J. F., Miller, D. D., and Patil, P. N., 1978, Conformation Of Dopamine At The Dopamine Receptor, Proc ...
  https://link.springer.com/chapter/10.1007/978-1-4684-4361-5_3