*  Virus grows tube to insert DNA during infection, then sheds it | NSF - National Science Foundation
... discovered a tube-shaped structure that forms temporarily in a certain type of virus to deliver its DNA during the infection ...
  https://www.nsf.gov/news/news_summ.jsp?cntn_id=129960
*  Viruses | Free Full-Text | The DNA Damage Response Induced by Infection with Human Cytomegalovirus and Other Viruses
Recent studies have shown that viruses can induce DNA damage response (DDR). Many of these viruses use DDR signaling to benefit ... Here, we review the DDR induced by HCMV infection and its similarities and differences to DDR induced by other viruses. As DDR ... their replication, while other viruses block or inactivate DDR signaling. This review focuses on the effects of DDR and DNA ... signaling pathways are critical for the replication of many viruses, blocking these pathways may represent novel therapeutic ...
  http://www.mdpi.com/1999-4915/6/5/2155/xml
*  A Study to Evaluate the Safety and Efficacy of Inactivated Varicella-zoster Vaccine (VZV) as a Preventative Treatment for...
Herpesviridae Infections. DNA Virus Infections. Virus Diseases. Vaccines. Immunologic Factors. Physiological Effects of Drugs. ... Has received a live virus vaccine or is scheduled to receive a live virus vaccine in the period from 4 weeks prior to Dose 1 ... or residence in a country with endemic VZV infection for ≥30 years or if participant is ,30 years old, attended primary or ... secondary school in a country with endemic VZV infection.. *Scheduled to undergo an autologous hematopoietic cell transplant ...
  https://clinicaltrials.gov/ct2/show/NCT01229267?recr=Open&cond=%22Chickenpox%22&rank=16
*  Phase II Trial to Assess Safety and Immunogenicity of IMVAMUNE® - Full Text View - ClinicalTrials.gov
Poxviridae Infections. DNA Virus Infections. Virus Diseases. Vaccines. Immunologic Factors. Physiological Effects of Drugs. ... Active exfoliative skin disorders/conditions, current varicella zoster virus infection, or any acute skin disorders of large ... Negative hepatitis B surface antigen and negative antibody to hepatitis C virus. ...
  https://clinicaltrials.gov/ct2/show/NCT01827371?recr=Open&cond=%22Poxviridae+Infections%22&rank=9
*  Treatment With Indinavir and Chemotherapy for Advanced Classical Kaposi's Sarcoma - Full Text View - ClinicalTrials.gov
Herpesviridae Infections. DNA Virus Infections. Virus Diseases. Neoplasms, Vascular Tissue. Protease Inhibitors. Indinavir. HIV ...
  https://clinicaltrials.gov/show/NCT01067690?order=76
*  SU5416 in Treating Patients With AIDS-Related Kaposi's Sarcoma - Full Text View - ClinicalTrials.gov
Herpesviridae Infections. DNA Virus Infections. Virus Diseases. Neoplasms, Vascular Tissue. To Top ... contraception No known allergy to Cremophor or Cremophor based drug product No concurrent uncontrolled serious infection such ...
  https://clinicaltrials.gov/show/NCT00003720?order=265
*  A Study to Compare the Efficacy and Safety of Valacyclovir Hydrochloride ( 256U87 ) Versus Acyclovir in the Treatment of...
Virus Diseases. Sexually Transmitted Diseases. Immunologic Deficiency Syndromes. Immune System Diseases. DNA Virus Infections. ... HIV Infections. Herpes Simplex. Herpesviridae Infections. Lentivirus Infections. Retroviridae Infections. RNA Virus Infections ... Versus Acyclovir in the Treatment of Recurrent Anogenital Herpes Infections in HIV Infected Patients. The safety and scientific ... Versus Acyclovir in the Treatment of Recurrent Anogenital Herpes Infections in HIV Infected Patients. ...
  https://clinicaltrials.gov/ct2/show/NCT00002000?cond=%22Sexually+Transmitted+Diseases%2C+Viral%22&rank=15
*  Safety, Tolerability and Immune Response of IMVAMUNE (MVA-BN)Smallpox Vaccine in HIV Infected Patients - Full Text View -...
HIV Infections. Smallpox. Lentivirus Infections. Retroviridae Infections. RNA Virus Infections. Virus Diseases. Sexually ... Uncontrolled serious infection i.e. not responding to antimicrobial therapy.. *History of any serious medical condition (other ... Subjects undergoing treatment for tuberculosis infection or disease.. *Having received any vaccinations or planned vaccinations ...
  https://clinicaltrials.gov/ct2/show/NCT00189904
*  Pilot Study of Liposomal Doxorubicin Combined With Bevacizumab Followed by Bevacizumab Monotherapy in Adults With Advanced...
Herpesviridae Infections. DNA Virus Infections. Virus Diseases. Neoplasms, Vascular Tissue. Bevacizumab. Liposomal doxorubicin ... Patients with human immunodeficiency virus (HIV) infection must be willing to comply with a regimen of highly active ... related KS or patients with KS unrelated to AIDS or human immunodeficiency virus (HIV) infection, whose KS that can be ... Kaposi's Sarcoma (KS) in patients who are Human immunodeficiency virus (HIV) Negative, HIV infected with stable disease for one ...
  https://clinicaltrials.gov/show/NCT00923936?order=119
*  Primary Transplant Donor Derived CMVpp65 Specific T-cells for The Treatment of CMV Infection or Persistent CMV Viremia After...
Virus Diseases. Sepsis. Systemic Inflammatory Response Syndrome. Inflammation. Pathologic Processes. Herpesviridae Infections. ... or detection of levels of CMV DNA in the blood or body fluids consistent with CMV infection. ... Patients with other conditions not related to CMV infection (e.g. uncontrolled bacterial sepsis or invasive fungal infection) ... T-cells are a type of white blood cell that helps protect the body from infection. A transfusion is the process by which blood ...
  https://www.clinicaltrials.gov/ct2/show/NCT01646645
*  Imatinib Mesylate in Treating Patients With HIV-Related Kaposi's Sarcoma - Full Text View - ClinicalTrials.gov
Herpesviridae Infections. DNA Virus Infections. Virus Diseases. Neoplasms, Vascular Tissue. Imatinib Mesylate. Antineoplastic ... Hepatitis C infection with minimal or no fibrosis on liver biopsy allowed ... Serological documentation of HIV infection, as evidenced by positive enzyme-linked immunosorbent assay (ELISA), Western Blot ... More than 14 days since prior acute treatment for an infection or other serious medical illness ...
  https://clinicaltrials.gov/show/NCT00090987
*  Paclitaxel in Treating Patients With AIDS-Related Kaposi's Sarcoma - Full Text View - ClinicalTrials.gov
Herpesviridae Infections. DNA Virus Infections. Virus Diseases. Neoplasms, Vascular Tissue. Paclitaxel. Albumin-Bound ... Serologic diagnosis of HIV infection documented by a positive ELISA and confirmed with a Western Blot or other federally ... Concurrent maintenance therapy for opportunistic infections allowed. *Concurrent commercially available antiretroviral therapy ...
  https://clinicaltrials.gov/show/NCT00003008?order=103
*  Valacyclovir Suppression to Improve the Stability of Vaginal Flora Among HSV-2 Seropositive Women - Full Text View -...
Herpesviridae Infections. DNA Virus Infections. Virus Diseases. Skin Diseases, Viral. Skin Diseases, Infectious. Skin Diseases ... history of acyclovir or valacyclovir resistant HSV infection. *Participation in a study using an investigational product in the ...
  https://clinicaltrials.gov/ct2/show/NCT00682721
*  Halofuginone Hydrobromide in Treating Patients With HIV-Related Kaposi's Sarcoma - Full Text View - ClinicalTrials.gov
Herpesviridae Infections. DNA Virus Infections. Virus Diseases. Neoplasms, Vascular Tissue. Halofuginone. Antineoplastic Agents ... Acute treatment for an infection (other than oral thrush or genital herpes) or other serious medical illness within 14 days of ... This phase II trial studies how well halofuginone hydrobromide works in treating patients with human immunodeficiency virus ( ... Concurrent, acute, active, untreated opportunistic infection other than oral thrush or genital herpes within 14 days of ...
  https://clinicaltrials.gov/show/NCT00064142?order=191
*  TACE and Adefovir Compared With Transarterial Chemoembolization (TACE) Alone for Hepatitis B Virus (HBV)-Related Unresectable...
Hepadnaviridae Infections. DNA Virus Infections. Virus Diseases. Hepatitis, Viral, Human. Chlorotrianisene. Adefovir. Adefovir ... Adefovir works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the ... Adefovir works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the ... TACE and Adefovir Compared With Transarterial Chemoembolization (TACE) Alone for Hepatitis B Virus (HBV)-Related Unresectable ...
  https://clinicaltrials.gov/ct2/show/study/NCT00960518?view=record
*  Study to Evaluate Efficacy, Safety, and Immunogenicity of GlaxoSmithKline (GSK) Biologicals' Herpes Zoster Vaccine...
Herpesviridae Infections. DNA Virus Infections. Virus Diseases. Vaccines. Immunologic Factors. Physiological Effects of Drugs. ... Prophylactic antiviral therapy with activity against Varicella Zoster Virus (VZV) expected to last more than 6 months after ... or a vesicular rash suggestive of VZV infection regardless of the distribution, and no alternative diagnosis; or (2) a clinical ... presentation (symptoms and/or signs) and specific laboratory findings* suggestive of VZV infection in the absence of ...
  https://clinicaltrials.gov/ct2/show/study/NCT01610414?show_locs=Y
*  Green Tea Extract in Preventing Cervical Cancer in Patients With Human Papillomavirus and Low-Grade Cervical Intraepithelial...
DNA Virus Infections. Tumor Virus Infections. Precancerous Conditions. Epigallocatechin gallate. Antioxidants. Molecular ... Cervical Cancer Cervical Intraepithelial Neoplasia Grade 1 Human Papilloma Virus Infection Drug: placebo Dietary Supplement: ... Virus Diseases. Carcinoma in Situ. Papilloma. Cervical Intraepithelial Neoplasia. Papillomavirus Infections. Uterine Cervical ... placebo-controlled trial of Polyphenon E in women with persistent high-risk HPV infection and low-grade cervical ...
  https://clinicaltrials.gov/ct2/show/study/NCT00303823
*  Herpes Simplex Virus Type 2 (HSV-2) Suppression to Prevent HIV Transmission - Full Text View - ClinicalTrials.gov
Herpesviridae Infections. DNA Virus Infections. Skin Diseases, Viral. Skin Diseases, Infectious. Skin Diseases. Genital ... Lentivirus Infections. Retroviridae Infections. RNA Virus Infections. Virus Diseases. Sexually Transmitted Diseases, Viral. ... HIV infection. HIV transmission. genital herpes. sexual intercourse. sexual transmitted infection. acyclovir. HIV ... Infection. HIV Infections. Herpes Simplex. Sexually Transmitted Diseases. Herpes Genitalis. ...
  https://clinicaltrials.gov/show/NCT00194519?order=297
*  Trial to Study the Effect of Dose of Herpes Simplex Virus-2 (HSV-2) Suppressive Therapy on HSV and HIV - Full Text View -...
Herpesviridae Infections. DNA Virus Infections. Skin Diseases, Viral. Skin Diseases, Infectious. Skin Diseases. Genital ... HIV Infections. Herpes Simplex. Herpes Genitalis. Lentivirus Infections. Retroviridae Infections. RNA Virus Infections. Virus ... The quantity of genital HSV DNA present, when HSV DNA was detected, was compared. ... Trial to Study the Effect of Dose of Herpes Simplex Virus-2 (HSV-2) Suppressive Therapy on HSV and HIV. The safety and ...
  https://clinicaltrials.gov/ct2/show/NCT00527618?term=%22+August+15%2C++2007%22%3A%22+September+14%2C++2007%22%5BFIRST-RECEIVED-DATE%5DAND+HIV%5BCONDITION%5D&rank=17
*  Study of Two Formulations of GSK Biologicals' Varicella Vaccine - Full Text View - ClinicalTrials.gov
Herpesviridae Infections. DNA Virus Infections. Virus Diseases. Vaccines. Immunologic Factors. Physiological Effects of Drugs. ... Antibody Titers Against Varicella Zoster Virus (VZV) [ Time Frame: At 43-57 days after the first vaccine dose (Week 6) ]. ... Antibody Titers Against Varicella Zoster Virus (VZV) [ Time Frame: At 86-114 days after the second vaccine dose (Week 12) ]. ... Antibody Concentrations Against Varicella Zoster Virus (VZV) [ Time Frame: At 43-57 days after the first vaccine dose (Week 6 ...
  https://clinicaltrials.gov/show/NCT00568334
*  Hepatitis B Vaccine in Patients With Inflammatory Bowel Disease - Full Text View - ClinicalTrials.gov
Hepadnaviridae Infections. DNA Virus Infections. Virus Diseases. Hepatitis, Viral, Human. Hepatitis. Liver Diseases. Digestive ... The objective is to assess the efficacy of Hepatitis B Virus vaccination in a population of IBD patients treated with ...
  https://clinicaltrials.gov/ct2/show/NCT01531075?recr=Open&cond=%22Intestinal+Diseases%22&rank=3
*  Antiretroviral Pregnancy Registry (APR): Multi-sponsor Registry to Detect Any Major Teratogenic Effect Involving Any of the...
Lentivirus Infections. Retroviridae Infections. RNA Virus Infections. Virus Diseases. Sexually Transmitted Diseases, Viral. ... HIV Infections. Hepatitis B. Liver Diseases. Digestive System Diseases. ...
  https://clinicaltrials.gov/show/NCT00404989?order=266
*  A Phase I Trial of Tecogalan Sodium (DS-4152) Administered as an Infusion Every 21 Days - Full Text View - ClinicalTrials.gov
HIV Infections. Sarcoma. Sarcoma, Kaposi. Lentivirus Infections. Retroviridae Infections. RNA Virus Infections. Virus Diseases ... Acute intercurrent infection other than genital herpes.. *Symptomatic or known central nervous system involvement (including ... NO symptomatic AIDS-defining opportunistic infection within the past 4 weeks.. *Recovered from toxicity of any prior anticancer ...
  https://clinicaltrials.gov/show/NCT00002136?order=108