*  Viruses | Free Full-Text | Coordinated DNA Replication by the Bacteriophage T4 Replisome
The helicase and primase also form a complex known as the primosome, which unwinds the duplex DNA while also synthesizing ... These purified proteins have been used to reconstitute DNA synthesis in vitro and are a well-characterized model system. Recent ... Since the leading and lagging strands are synthesized in opposite directions, coordination of DNA synthesis as well as priming ... Future studies will likely focus on defining the orientations and architecture of protein complexes at the replication fork. ...
  http://www.mdpi.com/1999-4915/7/6/3186
*  Compare the dna replication process in cells with the, Ask an Expert
... compare the dna replication process in cells with the process occurring in the pcr, Hire Biology Expert, Ask Academics Expert, ... 1- Compare the DNA Replication process in cells with the process occurring in the PCR replication. ...
  http://www.mywordsolution.com/question/compare-the-dna-replication-process-in-cells-with/928300
*  Structural studies of two key factors for DNA replication in eukaryotic cells :: University of Southern California...
... unwinds duplex DNA to enable DNA synthesis by polymerases. Eukaryotic DNA replication is a tightly regulated process and the ... DNA bending induced by LTag hexamer assembly at the replication origin at an angle to the global directionality of DNA creates ... Structural studies of two key factors for DNA replication in eukaryotic cells ... STRUCTURAL STUDIES OF TWO KEY FACTORS FOR DNA REPLICATION IN EUKARYOTIC CELLS by Yu-Hao Paul Chang A Dissertation Presented to ...
  http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/366483/rec/6
*  Reconstitution of complete SV40 DNA replication with purified replication factors - CSHL Scientific Digital Repository
Animals Cattle DNA Ligases metabolism DNA Replication DNA Viral biosynthesis DNA-Binding Proteins metabolism Exonucleases ... Using these proteins, complete SV40 DNA replication was reconstituted with only purified DNA replication factors: SV40 large ... Waga, S., Bauer, G., Stillman, B. (1994) Reconstitution of complete SV40 DNA replication with purified replication factors. ... Interestingly, whereas mammalian DNA ligase I functioned in the reconstituted replication system, mammalian DNA ligase III did ...
  http://repository.cshl.edu/25127/
*  Eukaryotic DNA Replication - J. Julian Blow - Oxford University Press
DNA replication is also a crucial step in the cell cycle, and recent improvements in our understanding of cell cycle control ... In this volume, the complexities of eukaryotic DNA replication are reviewed by leaders in this rapidly advancing field. ... A cell's ability to control replication of its DNA is fundamental to its normal development or transformation into a cancerous ... 2. SV40 DNA replication. 3. The initiation of DNA replication in the year Saccharomyces cerevisiae. 4. Replication origins in ...
  https://global.oup.com/academic/product/eukaryotic-dna-replication-9780199635856?cc=us&lang=en&tab=toc
*  UV-induced replication fork collapse in DNA polymerase η deficient cells is independent of the MUS81 endonuclease
replication fork progression, replication fork stability, re-priming, DNA damage signalling National Category Natural Sciences ... This was recently suggested in yeast and explains the formation of gaps during DNA replication on damaged DNA. Using a ... SET8 is required for replication fork progression, and depletion of SET8 led to the formation of replication-associated DNA ... UV-induced replication fork collapse in DNA polymerase η deficient cells is independent of the MUS81 endonuclease. Elvers, ...
  http://su.diva-portal.org/smash/record.jsf?pid=diva2:412225
*  KEGG PATHWAY: DNA replication - Dictyoglomus thermophilum
Generally, DNA replication follows a multistep enzymatic pathway. At the DNA replication fork, a DNA helicase (DnaB or MCM ... On the leading strand, replication occurs continuously in a 5 to 3 direction, whereas on the lagging strand, DNA replication ... The DNA primase (DnaG) is needed to form RNA primers. Normally, during replication of the lagging-strand DNA template, an RNA ... DNA replication - Dictyoglomus thermophilum [ Pathway menu , Organism menu , Pathway entry , Download KGML , Show description ...
  http://www.genome.jp/kegg-bin/show_pathway?dth03030+DICTH_0616
*  Distinct roles for Sld3 and GINS during establishment and progression of eukaryotic DNA replication forks | The EMBO Journal
To test whether Sld3 is essential for the progression of DNA replication forks during chromosome replication, we investigated ... Sangrithi MN, Bernal JA, Madine M, Philpott A, Lee J, Dunphy WG, Venkitaraman AR (2005) Initiation of DNA replication requires ... Differential assembly of Cdc45p and DNA polymerases at early and late origins of DNA replication. Proc Natl Acad Sci USA 96: ... Cobb JA, Bjergbaek L, Shimada K, Frei C, Gasser SM (2003) DNA polymerase stabilization at stalled replication forks requires ...
  http://emboj.embopress.org/content/25/8/1753
*  The DNA replication fork in eukaryotic cells - CSHL Scientific Digital Repository
The process of DNA replication is also coupled to cell-cycle progression and to DNA repair to maintain genome integrity. ... Replication of the two template strands at eukaryotic cell DNA replication forks is a highly coordinated process that ensures ... Waga, S., Stillman, B. (1998) The DNA replication fork in eukaryotic cells. Annual Review of Biochemistry, 67. pp. 721-51. ISSN ... Biochemical studies, principally of plasmid DNAs containing the Simian Virus 40 origin of DNA replication, and yeast genetic ...
  http://repository.cshl.edu/25131/
*  Simian virus 40 DNA replication in vitro: specificity of initiation and evidence for bidirectional replication.
Circular DNA molecules were found to be the best templates for DNA replication in the cell-free system; however, linear DNA ... Simian virus 40 DNA replication in vitro: specificity of initiation and evidence for bidirectional replication.. Li J.J., Kelly ... These findings provide further evidence that replication in the cell-free system faithfully mimics SV40 DNA replication in vivo ... Chinese hamster ovary cell extracts also supported SV40 DNA replication in vitro, but the extent of replication was ...
  http://www.uniprot.org/citations/2993858
*  Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair - CSHL Scientific Digital Repository
The ability of p21 to inhibit the role of PCNA in DNA replication but not in DNA repair rationalizes in vivo data showing that ... dna replication excision repair human human cell priority journal tumor suppressor gene p53 Cell Line Cyclins DNA Repair DNA, ... an essential DNA replication protein. However, PCNA is also required for nucleotide-excision repair of DNA, an intrinsic part ... DNA replication. bioinformatics , genomics and proteomics , genetics & nucleic acid processing , DNA, RNA structure, function, ...
  http://repository.cshl.edu/26489/
*  Guide to DNA Replication
... is the process of unraveling the Double Helix to create a template of matching DNA strands which creates a second set of DNA ... Learn about the DNA replication steps to better understand the process..... DNA Replication Errors DNA replication errors that ... More About Dna Replication. What is DNA Replication? The answer is essential to understanding the basic rules of genetics. An ... DNA replication is an important process resulting in the production of another copy of the DNA strand. Learn about the DNA ...
  http://www.brighthub.com/guides/dna-replication.aspx
*  What happens during DNA replication? | Reference.com
... two strands of DNA separate, and each separate strand forms a template to make a new strand. The replication process results in ... What enzymes are involved in DNA replication?. A: Many enzymes are involved in DNA replication, including DNA helicase, DNA ... What is DNA polymerase 1?. A: DNA polymerase I is an enzyme that plays a role in the process of DNA replication, according to ... What best describes the difference between transcription and DNA replication?. * How does an unwound strand of DNA begin to ...
  https://www.reference.com/science/happens-during-dna-replication-1774e347f301a6c5
*  KEGG PATHWAY: DNA replication + T30020
Generally, DNA replication follows a multistep enzymatic pathway. At the DNA replication fork, a DNA helicase (DnaB or MCM ... On the leading strand, replication occurs continuously in a 5 to 3 direction, whereas on the lagging strand, DNA replication ... The DNA primase (DnaG) is needed to form RNA primers. Normally, during replication of the lagging-strand DNA template, an RNA ... DNA replication + T30020 [ Pathway menu , Organism menu , Pathway entry , Download KGML , Show description , User data mapping ...
  http://www.genome.jp/kegg-bin/show_pathway?T30020_03030+M00262
*  Fighting Neuroblastomas by Blocking Their DNA Replication, Repair
PCNA is a protein essential to DNA repair and replication, and City of Hope researchers are targeting it in neuroblastoma cells ... PCNA, shown above, is a protein essential to DNA repair and replication, and City of Hope researchers are targeting it in ... R9-caPep's interference with PCNA in cancer cells led to inhibition of their DNA replication and repair abilities, as well as ... Gu and his team are currently conducting further studies to determine how R9-caPep disrupts DNA replication and repair in ...
  http://www.newswise.com/articles/fighting-neuroblastomas-by-blocking-their-dna-replication-repair
*  DNA replication licensing factor Mcm2 (IPR008045) | InterPro | EMBL-EBI
GO:0006270 DNA replication initiation Molecular Function. GO:0005524 ATP binding GO:0003677 DNA binding GO:0003678 DNA helicase ... DNA replication licensing factor MCM7, IPR008050. In addition to its role in initiation of DNA replication, Mcm2 is able to ... A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication.. Proc. Natl. Acad. ... Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing.. Cell 139 719-30 2009 ...
  http://www.ebi.ac.uk/interpro/entry/IPR008045
*  DNA Replication | S-cool, the revision website
Process of DNA replication The actual process is simple. To begin with one strand in the DNA duplex is nicked by the enzyme DNA ... The heavier the DNA, the further it moved down the centrifuge tubes. 15N DNA is heavier than 14N DNA. Mixed 14N and 15N DNA is ... What is the mechanism for this exact copying or replication of the DNA? Three theories existed: The parent DNA molecule breaks ... Several molecules of DNA polymerase act simultaneously, each assembling a separate section of the new strand of DNA. Each DNA ...
  https://www.s-cool.co.uk/a-level/biology/dna-and-the-genetic-code/revise-it/dna-replication
*  Protein Involved in DNA Replication Linked to Dwarfism
Not only are they involved in DNA replication; as Stillman (2009) and others have shown, a number of them are also known to be ... ORC enables a cell to keep track of its DNA replication and this is essential because the genetic material must be copied once ... The CSHL scientists suggest that centrosome reduplication as well as dysregulation of DNA replication (in which Orc1 is also ... DNA Finger Printing. DNA fingerprinting is a technique which helps forensic scientists and legal experts solve crimes, identity ...
  http://www.medindia.net/news/protein-involved-in-dna-replication-linked-to-dwarfism-104929-1.htm
*  DNA Replication Error-Induced Extinction of Diploid Yeast | Genetics
1994 The 3′→5′ exonucleases of both DNA polymerases δ and ε participate in correcting errors of DNA replication in ... DNA Replication Error-Induced Extinction of Diploid Yeast. Alan J. Herr, Scott R. Kennedy, Gary M. Knowels, Eric M. Schultz and ... DNA Replication Error-Induced Extinction of Diploid Yeast. Alan J. Herr, Scott R. Kennedy, Gary M. Knowels, Eric M. Schultz and ... DNA Replication Error-Induced Extinction of Diploid Yeast. Alan J. Herr, Scott R. Kennedy, Gary M. Knowels, Eric M. Schultz and ...
  http://www.genetics.org/content/196/3/677
*  DNA Replication
Your browser is not supported. Some parts of this page may not work. Please upgrade your browser for a better experience. Upgrade Browser ...
  https://padlet.com/rlcotter/Replication
*  What are the four steps of DNA replication? | Reference.com
The four steps of DNA replication are the unwinding of two coiled strands of DNA, complementary pairing of nucleotide bases, ... What is the result of the replication of one molecule of DNA?. A: The process of DNA replication takes one parental DNA ... What is the first step in the process of DNA replication?. A: The first step of DNA replication occurs when a protein triggers ... Unwinding must occur in order for DNA replication. Two strands of DNA that are connected and wound into a double helix separate ...
  https://www.reference.com/science/four-steps-dna-replication-7dbd5e3339555706
*  DNA replication - Wikipedia
Replication machineries include primosotors are replication enzymes; DNA polymerase, DNA helicases, DNA clamps and DNA ... Fixing of replication machineries as replication factories can improve the success rate of DNA replication. If replication ... ISBN 0-8153-3218-1. DNA Replication Mechanisms: DNA Topoisomerases Prevent DNA Tangling During Replication Reece, Richard J.; ... and the fragments of DNA are joined together by DNA ligase. As helicase unwinds DNA at the replication fork, the DNA ahead is ...
  https://en.wikipedia.org/wiki/DNA_replication
*  Eukaryotic DNA replication - Wikipedia
List of major proteins involved in Eukaryotic DNA replication DNA replication Prokaryotic DNA replication Processivity Leman AR ... During DNA replication, the replisome will unwind the parental duplex DNA into a two single-stranded DNA template replication ... Eukaryotic DNA replication is a conserved mechanism that restricts DNA replication to once per cell cycle. Eukaryotic DNA ... The process of semiconservative replication for the site of DNA replication is a fork-like DNA structure, the replication fork ...
  https://en.wikipedia.org/wiki/Eukaryotic_DNA_replication
*  Prokaryotic DNA replication - Wikipedia
The mutation rate per base pair per replication during phage T4 DNA synthesis is 1.7 per 108. Termination of DNA replication in ... DNA polymerase III holoenzyme is loaded into the DNA and replication begins. The catalytic mechanism of DNA polymerase III ... The rate of DNA replication in a living cell was first measured as the rate of phage T4 DNA elongation in phage-infected E. ... Prokaryotic DNA replication is the process by which a prokaryote duplicates its DNA into another copy that is passed on to ...
  https://en.wikipedia.org/wiki/Prokaryotic_DNA_replication
*  DNA replication factor CDT1 - Wikipedia
DNA replication factor Cdt1 is a protein that in humans is encoded by the CDT1 gene. The protein encoded by this gene is a key ... essential replication protein that colocalizes with the origin recognition complex and links DNA replication with mitosis and ... Nishitani H, Lygerou Z, Nishimoto T, Nurse P (2000). "The Cdt1 protein is required to license DNA for replication in fission ... "Entrez Gene: CDT1 chromatin licensing and DNA replication factor 1". Wohlschlegel JA, Dwyer BT, Dhar SK, Cvetic C, Walter JC, ...
  https://en.wikipedia.org/wiki/DNA_replication_factor_CDT1