*  KEGG PATHWAY: Base excision repair - Isoptericola variabilis
Base excision repair (BER) is the predominant DNA damage repair pathway for the processing of small base lesions, derived from ... BER is normally defined as DNA repair initiated by lesion-specific DNA glycosylases and completed by either of the two sub- ... Base excision repair - Isoptericola variabilis [ Pathway menu , Organism menu , Pathway entry , Download KGML , Show ... of BER relies on the formation of protein complexes that assemble at the site of the DNA lesion and facilitate repair in a ...
  http://www.genome.jp/kegg-bin/show_pathway?iva03410+Isova_2011
*  Focus Formation of DNA Repair Proteins in Normal and Repair-Deficient Cells Irradiated with High-LET Ions
Molecular biology, DNA damage, DNA repair, DSB, NHEJ, DNA-PK, ionising radiation, high-LET, heat-labile sites, PFGE, ... Focus Formation of DNA Repair Proteins in Normal and Repair-Deficient Cells Irradiated with High-LET Ions. Karlsson, Karin H ... Efficient and correct repair of DNA damage, especially DNA double-strand breaks (DSBs), is vital for the survival of individual ... 1. Role of Non-Homologous End-Joining in Repair of Radiation-Induced DNA Double-Strand Breaks. Open this publication in new ...
  http://uu.diva-portal.org/smash/record.jsf?pid=diva2:169135
*  KEGG PATHWAY: Nucleotide excision repair - Mycobacterium tuberculosis CCDC5079
Nucleotide excision repair (NER) is a mechanism to recognize and repair bulky DNA damage caused by compounds, environmental ... The repair of damaged DNA involves at least 30 polypeptides within two different sub-pathways of NER known as transcription- ... coupled repair (TCR-NER) and global genome repair (GGR-NER). TCR refers to the expedited repair of lesions located in the ... Nucleotide excision repair - Mycobacterium tuberculosis CCDC5079 [ Pathway menu , Organism menu , Pathway entry , Download KGML ...
  http://www.genome.jp/kegg-bin/show_pathway?mte03420
*  KEGG PATHWAY: Nucleotide excision repair - Neisseria meningitidis alpha710 (serogroup B)
Nucleotide excision repair (NER) is a mechanism to recognize and repair bulky DNA damage caused by compounds, environmental ... The repair of damaged DNA involves at least 30 polypeptides within two different sub-pathways of NER known as transcription- ... coupled repair (TCR-NER) and global genome repair (GGR-NER). TCR refers to the expedited repair of lesions located in the ... Nucleotide excision repair - Neisseria meningitidis alpha710 (serogroup B) [ Pathway menu , Organism menu , Pathway entry , ...
  http://www.genome.jp/kegg-bin/show_pathway?nmp03420
*  "Nucleotide Excision Repair Deficiency is Intrinsic in Sporadic Stage I" by Jean J. Latimer, Jennifer M. Johnson et al.
... tested with the functional unscheduled DNA synthesis assay exhibited a significant deficiency of DNA nucleotide excision repair ... Loss of DNA repair capacity, including the complex, damage-comprehensive NER pathway, results in genomic instabil- ity, a ... tested with the functional unscheduled DNA synthesis assay exhibited a significant deficiency of DNA nucleotide excision repair ... Loss of DNA repair capacity, including the complex, damage-comprehensive NER pathway, results in genomic instabil- ity, a ...
  http://nsuworks.nova.edu/hpd_com_faculty_articles/1110/
*  Study Reveals How Cells Remove Bits of RNA from DNA Strands
DNA »DNA repair »Escherichia coli »Gates Foundation »NSF »RNA »RNA/DNA »RNase »genetic mutation »genomic DNA »methanol fuel ... Further reports about: , DNA , DNA repair , Escherichia coli , Gates Foundation , NSF , RNA , RNA/DNA , RNase , genetic ... "We were excited to find that a DNA repair mechanism like mismatch repair was activated by RNA/DNA mismatches and could remove ... we plan to test whether other DNA repair mechanisms, such as nucleotide-excision repair and base-excision repair, can also ...
  http://www.innovations-report.com/html/reports/life-sciences/study-reveals-cells-remove-bits-rna-dna-strands-187083.html
*  The development of DNA repair assays which show that dietary carrots stimulate DNA repair activity - Surrey Research Insight...
The development of DNA repair assays which show that dietary carrots stimulate DNA repair activity ... The development of DNA repair assays which show that dietary carrots stimulate DNA repair activity In: 3rd Conference on Food ...
  http://epubs.surrey.ac.uk/824306/
*  Role of nucleotide excision repair factors in genome maintenance in human cells under oxidative stress | ScholarBank@NUS
Other DNA repair proteins including a component of the NER pathway, XPF, have been reported to be involved in telomere dynamics ... The role of nucleotide excision repair (NER) in the maintenance of DNA integrity under oxidative assault has yet to be ... Our findings have implications in the mechanisms of DNA repair in oxidative stress, mutagenesis, carcinogenesis and ageing. ... Although the NER is characterized to be involved in repairing UV-induced damage, it is difficult to attribute all the symptoms ...
  http://scholarbank.nus.edu.sg/handle/10635/16872
*  DNA Repair & Nucleic Acid Enzymology Group
... and its biological roles in base excision DNA repair. This DNA repair pathway protects cells against endogenous DNA lesion ... the study of gap-filling DNA synthesis in DNA repair. To define the biological role of DNA polymerase beta, the group and ... DNA Repair & Nucleic Acid Enzymology Group. Mechanisms of DNA Synthesis. Samuel H. Wilson, M.D. Principal Investigator Tel 984- ... the study of gap-filling DNA synthesis in DNA repair ("/Rhythmyx/assembler/render?sys_contentid=53298&sys_revision=1&sys_ ...
  https://www.niehs.nih.gov/research/atniehs/labs/gisbl/pi/dnarna/
*  DNA Repair
... provides a forum for the comprehensive coverage of DNA repair and cellular responses to DNA damage. The journal ... DNA Repair provides a forum for the comprehensive coverage of DNA repair and cellular responses to DNA damage. The journal ... DNA Repair provides a forum for the comprehensive coverage of DNA repair and cellular responses to DNA damage. The journal ... DNA Repair sponsors GRC DNA Damage, Mutation & Cancer 2018 * 3rd DNA Replication/Repair Structures and Cancer - Fusion ...
  https://www.journals.elsevier.com/dna-repair
*  DNA Repair and Simple Recombination | SpringerLink
... for repairing any damage). Nevertheless, most organisms can undergo some sort of... ... Birge E.A. (1994) DNA Repair and Simple Recombination. In: Bacterial and Bacteriophage Genetics. Springer, New York, NY. * DOI ... and RecA in replicative bypass of an abasic DNA lesion by DNA polymerase III. Proceedings of the National Academy of Sciences ... Madiraju, M.V.V.S., Clark, A.J. (1992). Evidence for ATP binding and double-stranded DNA binding by Escherichia coli RecF ...
  https://link.springer.com/chapter/10.1007/978-1-4757-2328-1_5
*  How DNA Repair Helps Prevent Cancer - Redorbit
Feig studies the proteins MutS and MSH2-MSH6, which recognize defective DNA and initiate DNA repair. Natural DNA repair occurs ... "DNA damage occurs frequently and if you couldn't repair your DNA, then you won't live for very long." This is because damaged ... "We believe that DNA bending facilitates the initial recognition of the mismatched base for repair," Feig said. "Normal DNA is ... In these cases, cancer is not a result of damaged DNA, but occurs because of a problem in the DNA repair mechanism itself. ...
  http://www.redorbit.com/news/health/1112926275/how-dna-repair-helps-prevent-cancer/
*  DNA repair protein XRCC4 (IPR010585) | InterPro | EMBL-EBI
... the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ... This entry represents the DNA double-strand break repair and V(D)J recombination protein XRCC4, which is found in certain ... XRCC4 binds to DNA, and to DNA ligase IV (LIG4) to form the LIG4-XRCC4 complex [PMID: 11029705]. The LIG4-XRCC4 complex is ... Requirement for XRCC4 and DNA ligase IV in alignment-based gap filling for nonhomologous DNA end joining in vitro.. Cancer Res. ...
  http://www.ebi.ac.uk/interpro/entry/IPR010585
*  Phys.org - dna repair
DNA repair. DNA repair refers to a collection of processes by which a cell identifies and corrects damage to the DNA molecules ... or one that no longer effectively repairs damage incurred to its DNA, can enter one of three possible states:. The DNA repair ... Snapshot of DNA repair. DNA is like the computer code of the body, and it must be preserved for our bodies to survive. Yet, as ... Consequently, the DNA repair process is constantly active as it responds to damage in the DNA structure. ...
  https://phys.org/tags/dna+repair/
*  Phys.org - dna repair
DNA repair. DNA repair refers to a collection of processes by which a cell identifies and corrects damage to the DNA molecules ... or one that no longer effectively repairs damage incurred to its DNA, can enter one of three possible states:. The DNA repair ... Consequently, the DNA repair process is constantly active as it responds to damage in the DNA structure. ... Researchers find that accurately transcribing DNA overrides DNA repair. A groundbreaking and surprising discovery provides a ...
  https://phys.org/tags/dna+repair/sort/liverank/all/
*  Recent Articles | Dna Repair | The Scientist Magazine®
A byproduct of alcohol consumption causes mutations in the DNA of mouse blood stem cells, and some of the breaks are not ... The Role of DNA Base Modifications. By Skirmantas Kriaucionis , September 1, 2017 ... Researchers develop a more-efficient method for rewriting DNA that could hold therapeutic value for HIV and other diseases. ... From DNA damage to cellular miscommunication, aging is a mysterious and multifarious process. ...
  https://www.the-scientist.com/?articles.list/categoryNo/2625/category/The-Scientist/tagNo/110/tags/DNA-repair/
*  DNA Repair in Skin Care
While DNA repair is occurring in our body roughly 100 trillion times every day, we apparently still need more help. There is a ... Our DNA is critical to our health and survival, but does our skin really benefit from this novel ingredient class? ... DNA is information everyone should become familiar with as we move to the next paradigm in skin care. ... delicate balance between oxygen being used a repair and sustain life and the infamous free radical cascade that is often the ...
  http://www.skininc.com/treatments/facial/antiaging/DNA-Repair-in-Skin-care--372234562.html
*  RCSB PDB - Gene View - BRCA1 - BRCA1, DNA repair associated
The PDB archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex assemblies. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists.
  http://www.rcsb.org/pdb/gene/BRCA1?chromosome=chr17&range=41243049&v=hg19
*  Scientists find DNA repair 'accuracy switch' | Cancer Research UK
UK scientists have shed light on how our cells use two different methods to repair damaged DNA, and how they switch between ... "Up to now, it was unclear how this accurate mechanism for repairing DNA breaks is turned on so we are very pleased with the ... UK scientists have shed light on how our cells use two different methods to repair damaged DNA, and how they switch between ... Cells have two main DNA repair pathways that were thought to function at different stages of a cell's life cycle and protect ...
  http://www.cancerresearchuk.org/about-us/cancer-news/news-report/2009-05-29-scientists-find-dna-repair-accuracy-switch
*  Detailed Look At A DNA Repair Protein In Action - Redorbit
... model of DNA repair, in which MutS proteins are the beads and DNA is the string. In solution, the MutS protein will bind to a ... A new and detailed look at the role of MutS in DNA's mismatch repair (MMR) system has been provided by a team of researchers ... "This is the first time we used this technique to look at a protein-mediated process like DNA repair in solution with multiple ... "The view of DNA as a passive element is at least in part due to a paucity of robust tools for examining dynamic DNA ...
  http://www.redorbit.com/news/science/1112983687/dna-repair-protein-in-action-102413/
*  BRIT1 Allows DNA Repair Teams Access To Damaged Sites - Redorbit
The team showed that normal BRIT1 aids repair of double-stranded DNA breaks by allowing access to two repair pathways: ... "Relaxing this barrier allows two different DNA repair pathways greater access to the damage, preventing flawed DNA from being ... a tumor-suppressing protein allows cellular repair mechanisms to pounce on damaged DNA by overcoming a barrier to DNA access. ... DNA repair efficiency dropped by between 40 and 60 percent in cells with BRIT1 knocked down that were then exposed to ionizing ...
  http://www.redorbit.com/news/health/1708573/brit1_allows_dna_repair_teams_access_to_damaged_sites/
*  Databases and Bioinformatics Tools for the Study of DNA Repair
There are also other mechanisms of DNA repair such as homologous recombination repair (HRR), nonhomologous end-joining repair ( ... Databases and Bioinformatics Tools for the Study of DNA Repair. Kaja Milanowska,1,2 Kristian Rother,1,2 and Janusz M. Bujnicki1 ... To counteract the deleterious effects of DNA damage, cells have developed various repair systems, including biochemical ... and nucleotide excision repair (NER) or specialized polymerases temporarily taking over lesion-arrested DNA polymerases during ...
  https://www.hindawi.com/journals/mbi/2011/475718/abs/
*  Mutant huntingtin impairs Ku70-mediated DNA repair. | Sigma-Aldrich
We identify Ku70, a component of the DNA damage repair complex, as a mediator of the DNA repair dysfunction in mutant Htt- ... DNA repair defends against naturally occurring or disease-associated DNA damage during the long lifespan of neurons and is ... Mutant huntingtin impairs Ku70-mediated DNA repair.. [Yasushi Enokido, Takuya Tamura, Hikaru Ito, Anup Arumughan, Akihiko ... and Htt further promotes DSBs by impairing DNA repair. ... Mutant Htt interacts with Ku70, impairs DNA-dependent protein ...
  https://www.sigmaaldrich.com/catalog/papers/20439996
*  Researchers Show How Cells' DNA Repair Machinery Can Destroy Viruses - Redorbit
Researchers Show How Cells' DNA Repair Machinery Can Destroy Viruses. by editor ... leaving the viral DNA so riddled with holes that it was beyond repair. "It's like dropping a nuclear bomb on the viral genome ... switches from repairing the DNA to chopping it up into unusable pieces. The researchers, who report the find in the Jan. 21 ... If there are many dUTPs floating around in the cell, they will likely make their way into the new viral DNA, and, potentially, ...
  http://www.redorbit.com/news/health/1112768243/researchers-show-how-cells-dna-repair-machinery-can-destroy-viruses/