Disease-Free Survival: Endpoint for Adjuvant Therapy for Cancer?
... discusses a recent article on the use of disease-free survival as a clinical endpoint. ... Thats what we generally call disease-free survival or event-free survival, and, of course, overall survival. ... As those of you who have heard me speak on this topic before know, I say that if you fall off that disease-free survival curve ... The article is "Youre Cured Till Youre Not: Should Disease-Free Survival Be Used as a Regulatory or Clinical End Point for ...
Roche's Xeloda Improves Disease-Free Survival after Colorectal Cancer Surgery
Stage III oxaliplatin boosts disease-free survival compared to combined postsurgery chemotherapy using 5-fluorouracil/ ... Home Topics Cancer Roches Xeloda Improves Disease-Free Survival after Colorectal Cancer Surgery ... oral anticancer drug Xeloda in combination with intravenous oxaliplatin immediately after surgery boosts disease-free survival ...
Vaccine increases disease-free survival for follicular lymphoma patients
A lymphoma vaccine uniquely tailored for each patient extends disease-free survival by 14 months, with signs of an even better ... Vaccine increases disease-free survival for follicular lymphoma patients. Jun 01, 2011 08:25 AM. By ... A lymphoma vaccine uniquely tailored for each patient extends disease-free survival by 14 months, with signs of an even better ... extending disease-free survival time from 28.7 months to 52.9 months. While those results need to be confirmed in randomized ...
Overall and Disease Free Survival After Minimally Invasive Esophagectomy - SAGES Abstract Archives
Objective: The objective of this study was to compare overall survival (OS) and disease free survival (DFS) among patients who ... Overall and Disease Free Survival After Minimally Invasive Esophagectomy. Abhishek Sundaram, MBBS MPH, Brittany L Willer, MD, ... median survival=52.6 months), MIE (median survival = 39.73 months) and THE (median survival=29.71 months). Neither was there a ... Kaplan-Meier survival analysis was used to evaluate OS and DFS. The log rank test was used to compare OS and DFS. ...
Stromal PD-L1 Expression Is Associated With Better Disease-Free Survival in Triple-Negative Breast Cancer
Keywords: Breast cancer; Disease-free survival; Full-face section; Overall survival; PD-1; PD-L1; Stromal PD-L1 expression; ... Tumor size, lymph node status, Ki-67 score, metastasis, overall survival (OS), and disease-free survival (DFS) were retrieved ... Stromal PD-L1 Expression Is Associated With Better Disease-Free Survival in Triple-Negative Breast Cancer Am J Clin Pathol. ...
Immunotherapy Duo Fails to Improve Disease-Free Survival in Patients With Kidney Cancer Following Surgery
Findings from the CheckMate-914 trial showed that Opdivo plus Yervoy did not meet the studys main goal of disease-free ... survival for patients with localized renal cell carcinoma, a type of kidney cancer. ... localized disease experience a five-year disease-free survival.. "Opdivo and Opdivo-based combinations have shown survival ... The main goal of the study was determining disease-free survival, with secondary goals of overall survival (time from treatment ...
Disease-Free Survival | Profiles RNS
"Disease-Free Survival" by people in this website by year, and whether "Disease-Free Survival" was a major or minor topic of ... "Disease-Free Survival" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... Below are the most recent publications written about "Disease-Free Survival" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Disease-Free Survival". ...
Disease-Free Survival: How Does Exercising Impact Colon Cancer? - Colon Cancer Foundation
For light-intensity to moderate-intensity activities, the 3-year disease-free survival (DFS) was 65.7% with 0.0 hour/wk ... 52Disease-Free Survival: How Does Exercising Impact Colon Cancer?. ... Feel free to contribute! Leave a Reply Cancel reply. You must be logged in to post a comment. ... Crohns Disease, Ulcerative Colitis, and Colorectal Cancer: How Different Are They?November 8, 2023 - 2:06 pm ...
Randomized Phase 3 Trial Shows Panitumumab Significantly Improved Progression-Free Survival and Disease Control in Metastatic...
Improvements in progression-free survival and disease control also occurred regardless of age, sex, primary tumor location ( ... Randomized Phase 3 Trial Shows Panitumumab Significantly Improved Progression-Free Survival and Disease Control in Metastatic ... Randomized Phase 3 Trial Shows Panitumumab Significantly Improved Progression-Free Survival and Disease Control in Metastatic ... Panitumumab improved progression-free survival and response rate regardless of the measured level or intensity of EGFr staining ...
The Effect of Monocyte Count on Disease-Free Survival in Esophageal Cancer Patients | Research Square
The 1-year disease-free survival rate was 60% and the 5-year disease-free survival rate was 33.2%. The estimated mean disease- ... Disease-free survival was 17.3 months (95% CI: 8.4-26.2) in patients with a monocyte count ≥515/μL as opposed to 38.5 months ( ... Disease-free survival was determined using the Kaplan-Meier curve. In univariate and multivariate analyses that were conducted ... By contrast, the strength of the study lies in the analysis of the effect of monocyte count alone on disease-free survival and ...
PTH-126 Azathioprine, steroids and the presence of inflammatory bowel disease before liver transplantation influence transplant...
... steroids and the presence of inflammatory bowel disease before liver transplantation influence transplant free survival in ... steroids and the presence of inflammatory bowel disease before liver transplantation influence transplant free survival in ... Cox regression analysis revealed that factors associated with transplant free survival were: AZA use before transplantation (p ... Patients with concomitant IBD had an increased transplant free survival compared to those without IBD. ...
No Disease-Free Survival Benefit of Adjuvant Sunitinib or Sorafenib in High-Risk Nonmetastatic Renal Cell Carcinoma - The ASCO...
No Disease-Free Survival Benefit of Adjuvant Sunitinib or Sorafenib in High-Risk Nonmetastatic Renal Cell Carcinoma. By Matthew ... Disease-Free Survival Due to low conditional power for the primary endpoint, the Data Safety Monitoring Committee recommended ... Five-year disease-free survival was 54.3%, 54.0%, and 56.4%, respectively.. Among patients with clear cell histology ( ... The primary objective was to compare disease-free survival between each experimental group and placebo in the intention-to- ...
Isolated tumor cells in stage I & II colon cancer patients are associated with significantly worse disease-free and overall...
II colon cancer patients are associated with significantly worse disease-free and overall survival. Based on these data, the ... The presence of ITC was associated with a significantly worse disease-free survival (hazard ratio = 4.73, p = 0.005). Similarly ... The impact of ITC on survival was assessed using Cox regression analyses. Median follow-up was 4.6 years. ITC were ... ITC were associated with significantly worse overall survival (hazard ratio = 3.50, p = 0.043). This study provides ...
Prognostic Value of Preoperative Metabolic Tumor Volumes on PET-CT in Predicting Disease-free Survival of Patients with Stage I...
A: Disease-free survival curves according to early standardized uptake values (eSUVm). Data represent eSUVm ,2.5 and eSUVm ≤2.5 ... B: Disease-free survival curves according to delayed SUVmax (lSUVm). Data represent lSUVm ,3.4 and lSUVm ≤3.4. ... Disease-free survival curves based on metabolic tumor volume2.5 ,9.8 ml and MTV2.5 ≤9.8 ml. ... Prognostic Value of Preoperative Metabolic Tumor Volumes on PET-CT in Predicting Disease-free Survival of Patients with Stage I ...
ISPOR - Real-World Progression-Free Survival by Timing of Molecular Profiling Testing Among Metastatic Non-Small Cell Lung...
... cohort A had a lower risk of disease progression (HR=0.665; p=0.023).,/p> ,b>CONCLUSIONS : ,/b>Patients with mNSCLC may benefit ... Baseline demographic and clinical characteristics and progression-free survival (PFS) were compared between patients with ≥1 ... Real-World Progression-Free Survival by Timing of Molecular Profiling Testing Among Metastatic Non-Small Cell Lung Cancer ... Baseline demographic and clinical characteristics and progression-free survival (PFS) were compared between patients with ≥1 ...
Efficacy of Extended Duration vs Perioperative Thromboprophylaxis With Tinzaparin on Disease-Free Survival After Surgical...
Efficacy of Extended Duration vs Perioperative Thromboprophylaxis With Tinzaparin on Disease-Free Survival After Surgical ... Progression-Free Survival Increased With Zanubrutinib in Leukemia * Comparison of the Effectiveness and Safety of Direct Oral ... and safety of extended duration to perioperative thromboprophylaxis with low molecular weight heparin on disease-free survival ... PracticeUpdate is free to end users but we rely on advertising to fund our site. Please consider supporting PracticeUpdate by ...
Neoadjuvant Androgen Deprivation Therapy in Prostate Cancer: Overview, Androgen Deprivation, Selection of Candidates for NADT
Overall and Disease-Free Survival. A systematic review and meta-analysis of neoadjuvant androgen deprivation therapy (NADT) in ... Superior PSA progression-free survival; drug likely delays progression to castration-resistant disease.. Flushing, injection ... Superior PSA progression-free survival; drug likely delays progression to castration-resistant disease.. Flushing, injection ... Similarly, Klotz et al found that 5-year biochemical disease-free survival was 60.2% and 68.2%, respectively, for the NADT and ...
Disease-Free Survival | Profiles RNS
"Disease-Free Survival" by people in this website by year, and whether "Disease-Free Survival" was a major or minor topic of ... "Disease-Free Survival" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... Below are the most recent publications written about "Disease-Free Survival" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Disease-Free Survival". ...
Poverty associated with worse survival, fewer lung transplants in lung disease patients
... a rare lung disease that causes shortness of breath and low oxygen levels because of lung scarring, have worse outcomes if they ... Donate and enjoy an ad-free experience. We keep our content available to everyone. Consider supporting Science Xs mission by ... Poverty associated with worse survival, fewer lung transplants in lung disease patients. by American Thoracic Society ... Poverty associated with worse survival, fewer lung transplants in lung disease patients. ...
Survival after breast cancer recurrence: effect of the disease-free interval</em>...
Survival after breast cancer recurrence: effect of the disease-free interval. Annemieke Witteveen, A.B.G. Kwast, G.S. Sonke, ... Survival after breast cancer recurrence: effect of the disease-free interval. / Witteveen, Annemieke; Kwast, A.B.G.; Sonke, G.S ... Survival after breast cancer recurrence: effect of the disease-free interval. Poster session presented at 39th WEON Conference ... Survival after breast cancer recurrence: effect of the disease-free interval. 2014. Poster session presented at 39th WEON ...
Validation of Progression-Free Survival as a Surrogate Endpoint for Overall Survival in Malignant Mesothelioma: Analysis of...
With a short postprogression survival and a moderate correlation between PFS and OS, there is no evidenc … ... The Oncologist 2017;22:189-198Implications for Practice: For better disease management and for more efficient clinical trial ... Validation of Progression-Free Survival as a Surrogate Endpoint for Overall Survival in Malignant Mesothelioma: Analysis of ... Keywords: Malignant mesothelioma; Overall survival; Progression‐free survival; Risk factors; Surrogate endpoint. ...
Frontiers | A Clinical-Genetic Score to Identify Surgically Resected Colorectal Cancer Patients Benefiting From an Adjuvant...
... aim was to integrate our previously reported clinical-genetic prognostic score with new immunogenetic markers of 5-year disease ... free survival (DFS) to evaluate the recurrence risk stratification before fluoropyrimidine (FL)-based adjuvant therapy. The ... aim was to integrate our previously reported clinical-genetic prognostic score with new immunogenetic markers of 5-year disease ... free survival (DFS) to evaluate the recurrence risk stratification before fluoropyrimidine (FL)-based adjuvant therapy. The ...
Correlation of changes between 2-year disease-free survival and 5-year overall survival in adjuvant breast cancer trials from...
Correlation of changes between 2-year disease-free survival and 5-year overall survival in adjuvant breast cancer trials from ... BACKGROUND: Although disease-free survival (DFS) is accepted as a valid end point in adjuvant breast cancer trials, improvement ... in 2-year DFS has never been formally established as an adequate correlate for 5-year overall survival (OS). We set out to ...
Comorbid Diseases Lessen Survival Benefit of Aggressive PCa Therapy - Renal and Urology News
Register for free and gain unlimited access to:. - Clinical News, with personalized daily picks for you. - Case Studies. - ... Close more info about Comorbid Diseases Lessen Survival Benefit of Aggressive PCa Therapy ... Close more info about Comorbid Diseases Lessen Survival Benefit of Aggressive PCa Therapy ... Close more info about Comorbid Diseases Lessen Survival Benefit of Aggressive PCa Therapy ...
Skyrim Getting A Tough-Sounding Survival Mode, Beta Out Now On PC - GameSpot
If you dont cure yourself, a disease can get worse.. *Shrines dont cure diseases for free; instead you have to make a gold ... PC players can try the Survival mode right now on Steam by opting into the Steam beta. Xbox One and PS4 users can check it out ... The third main pillar of Survival mode is weather. When it gets cold in Skyrim, youll need to bundle up. Fail to do so and ... Bethesda also said the mode will be free during its launch week on each platform, so if youre interested, you may want to get ...
Long-term survival and state of health after paediatric intensive care. | Archives of Disease in Childhood
Long-term survival and state of health after paediatric intensive care.. Free ... Survival and state of health were assessed one year after discharge in 468 children admitted to an intensive care unit (ICU). ... cumulative one year survival was favourable and health status in three quarters of the population was preserved. ...
News 2021 | The University of Edinburgh
Better post-surgery care would improve cancer survival. *New free online course: Chronic Respiratory Diseases (CRD) in Primary ... New free online course: Chronic Respiratory Diseases (CRD) in Primary Care Settings. ... Better post-surgery care would improve cancer survival. Patients chances of survival after cancer surgery is strongly linked ... Smoke-free cars can cut child tobacco risk by a third. Banning in-car smoking when children are present can reduce their ...
New data: Celldex brain cancer vaccine boosts long-term survival in advanced disease | BioPharma Dive
... met its main goal of showing that Rintega-treated patients experienced at least six months of progression-free survival. ... New data: Celldex brain cancer vaccine boosts long-term survival in advanced disease ... According to the American Brain Tumor Association, the two-year survival rate for glioblastoma is 30%, while the five-year ... Get the free newsletter. Subscribe to BioPharma Dive for top news, trends & analysis ...
ADC Makes a Case for Role in Metastatic HER2-Positive Breast Cancer | MedPage Today
Improved progression-free survival in previously treated disease with trastuzumab duocarmazine ... Improved progression-free survival in previously treated disease with trastuzumab duocarmazine. by Charles Bankhead, Senior ... Median progression-free survival (PFS) improved from 4.9 months with investigators choice of chemotherapy to 7.0 months with ... "Treatment with SYD985 significantly improved progression-free survival in comparison with standard physicians choice treatment ...
Erratum to "Prognostic factors affecting disease-free survival and overall survival in T4 colon cancer"
Prognostic factors affecting disease-free survival and overall survival in T4 colon cancer. Ann Coloproctol 2021;37:259-65.. ... Prognostic Factors Affecting Disease-Free Survival and Overall Survival in T4 Colon Cancer2021 August;37(4) ... In the article titled "Prognostic factors affecting disease-free survival and overall survival in T4 colon cancer [1]," the ... Erratum to "Prognostic factors affecting disease-free survival and overall survival in T4 colon cancer". ...