Axonal swellings in neurons from STZ-diabetic rats expo | Open-i
Diabetes Mellitus, Experimental/metabolism/pathology*. *Glucose/pharmacology*. *Oxidative Stress/drug effects/physiology* ... Conclusions: Dorsal root ganglia neurons with a history of diabetes expressed low MnSOD and high ROS in axons. Oxidative stress ... Conclusions: Dorsal root ganglia neurons with a history of diabetes expressed low MnSOD and high ROS in axons. Oxidative stress ... We tested the hypothesis that sensory neurons exposed to type 1 diabetes would exhibit enhanced ROS and oxidative stress and ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC2682687_zdb0050957020007&req=4
Influence of Experimental Diabetes Mellitus on Secretary Granules in ß-Cells in the Dog Pancreatic Islet
... , Yuji Asai, Hiroyuki ... Influence of Experimental Diabetes Mellitus on Secretary Granules in ß-Cells in the Dog Pancreatic Islet. Yuji Asai1, Hiroyuki ... One was a control group and the other served as those with experimental diabetes mellitus (DM) and received injections of ... Diabetes 1972; 21:1051-1059.. *Chang AY, Diani AR. Chemically and hormonally induced Diabetes Mellitus. In: The Diabetic ...http://www.alliedacademies.org/articles/influence-of-experimental-diabetes-mellitus-on-secretary-granules-in-cells-in-the-dog-pancreatic-islet.html
Effects of ageing and streptozotocin-induced diabetes on connexin43 and P2 purinoceptor expression in the rat corpora cavernosa...
CONCLUSION Ageing and diabetes mellitus markedly altered the expression of the gap junction protein Cx43 and of particular P2R ... There was already development of erectile dysfunction and bladder overactivity at 2 months after inducing diabetes, the ... 4 and 8 months after diabetes induction by in vivo cystometry and cavernosometry. Corporal and bladder tissue were then ... OBJECTIVE To investigate whether ageing and diabetes alter the expression of the gap junction protein connexin43 (Cx43) and of ...https://www.semanticscholar.org/paper/Effects-of-ageing-and-streptozotocin-induced-diabe-Suadicani-Urban-Maldonado/a230dc2f1c86aecfeba58c0a564deb1db120202a
Metabolic Studies Using Rat as Model Organism sub-cluster 48
Muscarinic receptors mediate cold stress-induced detrusor overactivity in type 2 diabetes mellitus rats. ... The aim of this experimental study was to evaluate the expression of 4 genes (osteocalcin, sclerostin (SOST), insulin receptor ... Diabetes and glucose influence vasoresponsiveness but their impact on the intrahepatic vascular bed in cirrhosis is unknown. To ... if muscarinic receptors could mediate the cold stress-induced detrusor overactivity induced in type 2 diabetes mellitus rats. ...http://www.biomedsearch.com/cluster/0/Metabolic-Studies-Using-Rat-as-Model-Organism/sub-48.html
Intraocular Delivery of miR-146 Inhibits Diabetes-Induced Retinal Functional Defects in Diabetic Rat Model | IOVS | ARVO...
Rats with blood glucose level greater than 250 mg/dL were deemed as diabetes (diabetes mellitus, DM). ... Experimental details (e.g., the timing of tissue harvesting) may also influence the outcomes of the observation, as miR-146a ... One week after diabetes, animals were injected with lentivirus intravitreally (4 μl, ∼106 CFU/mL). Three months after diabetes ... Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections. Diabetes Care. 1998; 21: 1414-1431. ...http://iovs.arvojournals.org/article.aspx?articleid=2612690
Supplement to Uncoupling Endothelial Nitric Oxide Synthase Is Ameliorated by Green Tea in Experimental Diabetes Mellitus by Re...
Uncoupling Endothelial Nitric Oxide Synthase Is Ameliorated by Green Tea in Experimental Diabetes Mellitus by Re-Establishing ... 2017 by the American Diabetes Association. Diabetes Print ISSN: 0012-1797, Online ISSN: 1939-327X. ...http://diabetes.diabetesjournals.org/content/suppl/2012/05/11/db11-1241.DC1
Increased Persistent Sodium Current Due to Decreased PI3K Signaling Contributes to QT Prolongation in the Diabetic Heart |...
Diabetes mellitus attenuates the repolarization reserve in mammalian heart. Cardiovasc Res 2007;73:512-520pmid:17182020. ... Action potentials and potassium currents in rat ventricular muscle during experimental diabetes. J Mol Cell Cardiol 1992;24:841 ... European Association for the Study of Diabetes (EASD). . Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: ... Prolonged QTc interval predicts mortality in patients with type 1 diabetes mellitus. Diabet Med 2001;18:199-205pmid:11318840. ...http://diabetes.diabetesjournals.org/content/62/12/4257?with-ds=yes
Mesenchymal Stem Cell Therapy in Type 1 Diabetes Mellitus and Its Main Complications: From Experimental Findings to Clinical...
Type 1 diabetes mellitus (T1DM) is a complex multifactorial disorder which involves a loss of self-tolerance leading to the ... Mesenchymal Stem Cell Therapy in Type 1 Diabetes Mellitus and Its Main Complications: From Experimental Findings to Clinical ... Mesenchymal Stem Cell Therapy in Type 1 Diabetes Mellitus and Its Main Complications: From Experimental Findings to Clinical ... Type 1 diabetes mellitus (T1DM) is a complex multifactorial disorder which involves a loss of self-tolerance leading to the ...https://www.omicsonline.org/open-access/mesenchymal-stem-cell-therapy-in-type-diabetes-mellitus-and-its-main-complications-from-experimental-findings-to-clinical-practice-2157-7633.1000227.php?aid=30007
Renal prostanoids in experimental diabetes mellitus
Reference: Kucherenko A.G., Zadkova G.F., Markov Kh.M., Poleshchuk V.S., Renal prostanoids in experimental diabetes mellitus, ... Abstract: Participation of renal prostanoids in development of diabetes-induced nephropathy was studied in rats with ... to formation of diabetic nephropathy in the experimental animals. ... streptozotocin diabetes. Development of diabetic nephropathy occurred with simultaneous decreases in production of intrarenal ...http://pbmc.ibmc.msk.ru/index.php/en/article/PBMC-1994-40-6-37-en
An integrated experimental and computational approach to understanding complex disease: Differential gene expression in type 2...
Using Type 2 Diabetes Mellitus (T2DM) as a sample complex disease, I show that using combined criteria for differential gene ... Subject(s): Approach, Complex, Computational, Diabetes, Differential Gene Expression, Disease, Experimental, Genetic Linkages, ... An integrated experimental and computational approach to understanding complex disease: Differential gene expression in type 2 ... By definition, complex diseases (e.g. hypertension, diabetes, asthma) demonstrate both environmental and genetic factors in ...https://deepblue.lib.umich.edu/handle/2027.42/124505
Effect of Experimental Diabetes Mellitus on some Biochemical Parameters and Histopathological Changes in Pancreas Liver Kidney...
The present study investigated the effects of diabetes on some biochemical parameters and histopathological changes in ... Menopause is a physiological process and diabetes is a metabolic disease that occurs more frequently in older women. ... Effect of Experimental Diabetes Mellitus on some Biochemical Parameters and Histopathological Changes in Pancreas, Liver, ... Namjoo A R, Heidarian E, Rafieian-Kopaei M, Safarian M. Effect of Experimental Diabetes Mellitus on some Biochemical Parameters ...http://jmums.mazums.ac.ir/browse.php?a_id=8003&sid=1&slc_lang=en
An Experimental study of Macroangiopathy, a common complication of Diabetes Mellitus, with Ayurveda perspective
... a common complication of Diabetes Mellitus, with Ayurveda perspective Prof. Ojha S. N. M.D.(Ayu.) Ph.D. Principal Dr. D.Y Patil ... The prevalence of macroangiopathy is increased in Diabetes Mellitus. ► Endothelial cell injury is thought to be an early event ... An Experimental study of Macroangiopathy, a common complication of Diabetes Mellitus, with Ayurveda perspective. Posted January ... Tagged: ayurveda, charak., Dhamanipratichaya, Diabetes Mellitus, Dr. D.Y Patil college of ayurved and research centre, ...https://drojha.wordpress.com/2012/01/12/an-experimental-study-of-macroangiopathy-a-common-complication-of-diabetes-mellitus-with-ayurveda-perspective/
Metabolic and functional alterations of copper in diabetes mellitus
Estudos sobre cobre e diabetes mellitus experimental O papel do cobre na homeostase da glicose tem sido pouco estudado, no ... cobre e diabetes mellitus em humanos As implicações patogênicas das alterações do estado nutricional de cobre no diabetes, ... and magnesium status and complications of diabetes mellitus. Diabetes Care, New York, v.14, n.11, p.1050-1056, 1991. [ Links ] ... in experimental diabetes. Reversal by b-aminopropionitrile and D-penicillamine. Diabetes, New York, v.29, n.10, p.778-781, 1980 ...http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-52731999000300002
Intestinal Metabolic Reprogramming as a Key Mechanism of Gastric Bypass in Humans - Full Text View - ClinicalTrials.gov
Diabetes Mellitus, Experimental/metabolism. Energy Metabolism. Glucose/metabolism. Jejunum/metabolism. Metabolomics. Gene ... Diabetes Mellitus. Diabetes Mellitus, Type 2. Metabolic Diseases. Glucose Metabolism Disorders. Endocrine System Diseases. ... Obesity Diabetes Mellitus, Type 2 Endocrine System Diseases Glucose Metabolism Disorders Metabolic Diseases ... is the best current treatment option for obesity-related Type 2 Diabetes Mellitus (T2DM). The mechanisms underlying RYGBS- ...https://clinicaltrials.gov/ct2/show/NCT02710370
ATP-dependent K(+) channels contribute to local metabolic coronary vasodilation in experimental diabetes.
Diabetes Mellitus, Experimental / physiopathology*. Dogs. Female. Glyburide / pharmacology. Heart Rate / drug effects. Hydrogen ... Title: Diabetes Volume: 51 ISSN: 0012-1797 ISO Abbreviation: Diabetes Publication Date: 2002 Apr ... Diabetes significantly reduced myocardial O(2) delivery and lowered coronary venous PO(2) from 16.3 +/- 0.6 mmHg at rest to ... Data were collected at rest and during exercise before and after induction of diabetes with alloxan monohydrate (40-60 mg/kg ...http://www.biomedsearch.com/nih/ATP-dependent-K-channels-contribute/11916945.html
Food intake in free-feeding and energy-deprived lean rats is mediated by the neuropeptide Y5 receptor.
Diabetes Mellitus, Experimental / physiopathology. Drinking / drug effects. Eating / drug effects. Humans. Hypothalamus / ...http://www.biomedsearch.com/nih/Food-intake-in-free-feeding/9854049.html
Antinociceptive effect of L-arginine in diabetic mice.
Diabetes Mellitus, Experimental / physiopathology*. Dose-Response Relationship, Drug. Endorphins / administration & dosage, ...http://www.biomedsearch.com/nih/Antinociceptive-effect-L-arginine-in/8206107.html
The biological origin of ketotic dicarboxylic aciduria. In vivo and in vitro investigations of the omega-oxidation of C6-C16...
Diabetes Mellitus, Experimental / metabolism*. Diabetic Ketoacidosis / metabolism*. Dicarboxylic Acids / metabolism*. Fatty ...http://www.biomedsearch.com/nih/biological-origin-ketotic-dicarboxylic-aciduria/6798996.html
Eda Cengiz, MD, MHS, FAAP | Yale School of Medicine
Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetes Complications Research ... Insulin & Diabetes Mellitus. Insulin & Diabetes Mellitus. Tania S. Burgert, Eda Cengiz, William V. Tamborlane.Neonatal & ... Type 1 Diabetes Exchnage and Pediatric Diabetes Consortium (PDC) project: building a database to monitor diabetes management ... The pediatric diabetes consortium: improving care of children with type 1 diabetes through collaborative research. Diabetes ...http://medicine.yale.edu/intranet/facultybydept/eda_cengiz-2.profile
Pressure Oscillation Regulates Human Mesangial Cell Growth and Collagen Synthesis | Hypertension
Glomerular hemodynamics in experimental diabetes mellitus. Kidney Int. 1981;19:410-415. ... Abstract-Experimental renal disease models establish glomerular hypertension as a crucial determinant in glomerulosclerosis ... In these studies, cells grown under either experimental conditions, AP or OP, stained intensively for vimentin and smooth ... 1 2 3 4 Experimental models have shown that changes in intracapillary pressure are accompanied by a loss of afferent arteriole ...http://hyper.ahajournals.org/content/32/5/945
Renal Changes on Hyperglycemia and Angiotensin-Converting Enzyme in Type 1 Diabetes | Hypertension
Glomerular hemodynamics in experimental diabetes mellitus. Kidney Int.. 1981;19:410-415. ... Epidemiologic approach to the etiology of type I diabetes mellitus and its complications. N Engl Med.. 1987;317:1390-1398. ... In experimental diabetes, high blood glucose causes high intraglomerular hydraulic pressure, glomerular filtration rate (GFR), ... Role of endothelium derived nitric oxide in the pathogenesis of the renal hemodynamic changes of experimental diabetes. ...http://hyper.ahajournals.org/content/33/3/775
Potassium Channel Function in Vascular Disease | Arteriosclerosis, Thrombosis, and Vascular Biology
Glomerular hemodynamics in experimental diabetes mellitus. Kidney Int. 1981;19:410-415. ... Cardiovascular disease and hypertension in diabetes mellitus. Diabetes Metab Rev. 1989;5:547-558. ... Effect of diabetes mellitus on response of the basilar artery to activation of ATP-sensitive potassium channels. Brain Res. ... Exaggerated impact of ATP-sensitive K+ channels on afferent arteriolar diameter in diabetes mellitus. J Am Soc Nephrol. 2000;11 ...http://atvb.ahajournals.org/content/21/1/28
Effect of ficus relegiosa on blood glucose and total lipid levels of normal and alloxan diabetic rabbits. | CureHunter
Diabetes Mellitus, Experimental (blood) *Islets of Langerhans (drug effects, secretion) *Lipids (blood) ... This study was performed to study the possible role of indigenous medicinal plants in the treatment of Diabetes mellitus (type- ...http://www.curehunter.com/public/pubmed15067832.do
Pasireotide & Everolimus in Adult Patients With Radioiodine-Refractory Differentiated & Medullary Thyroid Cancer - Full Text...
Patients with uncontrolled diabetes mellitus or a fasting plasma glucose , 1.5 ULN. Note: At the principal investigator's ... Experimental: Arm C (Everolimus + Pasireotide) CURRENTLY CLOSED TO ACCRUAL. Drug: Everolimus and Pasireotide Everolimus 10 mg ... Experimental: Arm B (Pasireotide alone) CURRENTLY CLOSED TO ACCRUAL--Pasireotide alone followed by Everolimus + Pasireotide at ... Experimental: Arm A (Everolimus alone) Everolimus alone followed by Everolimus + Pasireotide at the time of progression ...https://clinicaltrials.gov/ct2/show/NCT01270321?term=sirolimus+cancer&recr=Open&rank=17
Vacancy for Assistant Manager - Corporate Quality Assurance at J. B. Chemicals & Pharmaceuticals | PharmaTutor
An Overview on Polymeric Nanoparticles used in the treatment of Diabetes Mellitus ... Nitric oxide: Experimental analysis of its role in brain tissue in simulated ischemia ...http://www.pharmatutor.org/content/march-2017/vacancy-for-assistant-manager-corporate-quality-assurance-at-jb-chemicals-and-pharmaceuticals