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*  Wild Sex in Zebrafish: Loss of the Natural Sex Determinant in Domesticated Strains | Genetics
2012 Multiple sex-associated regions and a putative sex chromosome in zebrafish revealed by RAD mapping and population genomics ... a model for development and human health. We used RAD-tag population genomics to identify sex-linked polymorphisms. After ... perhaps due to polygenic sex determination unmasked by the evolutionary strengthening of weak sex-ratio modifiers under the ... 2001 Meiotic chromosomes and stages of sex chromosome evolution in fish: zebrafish, platyfish and guppy. Chromosome Res. 9: 659 ...
  http://www.genetics.org/content/198/3/1291.full
*  Scientists Map Sex Chromosome Evolution in Fungi | Duke Today
"But in each of these lineages, there are multiple evolutionary events that have occurred, and you can use genomics to turn back ... According to their model, multiple translocations deposited the two sex determinants on the same chromosome, with a centromere ... essentially mimicking the human X or Y chromosome.. Surprisingly, they've shown that these crucial translocations occurred at ... on the sex chromosomes. In humans, those chromosomes go by the familiar X and Y; in birds, they are known as Z and W; in moss, ...
  https://today.duke.edu/2017/08/scientists-map-sex-chromosome-evolution-fungi
*  Browsing Genetics by Title
As humans are diploid organisms with two copies of each chromosome (except for the sex chromosomes in ... ... Patterns and determinants of variation in functional genomics phenotypes in the yeast Saccharomyces cerevisiae  Skelly, Daniel ... Population genomic insights into recent human evolutionary history  Emery, Leslie S. (2014-04-30) ... Sex and reproduction have long been recognized as drivers of distinct evolutionary phenotypes. Studying the evolution and ...
  https://digital.lib.washington.edu/researchworks/handle/1773/4923/browse?rpp=20&etal=-1&type=title&starts_with=N&order=ASC&sort_by=1
*  Gene expression and fast-X in mammals | Biology Letters
We report that the human X chromosome does indeed have a higher DoS than the autosomes (−0.134 versus −0.171 for X chromosome ... 1987 The relative rates of evolution of sex chromosomes and autosomes. Am. Nat. 130, 113. (doi:10.1086/284701). ... 2014 OrthoMaM v8: a database of orthologous exons and coding sequences for comparative genomics in mammals. Mol. Biol. Evol. 31 ... 2012 Mechanisms and evolutionary patterns of mammalian and avian dosage compensation. PLoS Biol. 10, e1001328. (doi:10.1371/ ...
  http://rsbl.royalsocietypublishing.org/content/11/2/20150010
*  UW Genome Sciences: past GS Seminars
What do sex chromosomes have to do with sex?' April 1 - Dr. Aimee Dudley. Institute for Systems Biology. "Integrating spatial ... Towards a human cell atlas'. January 7 - Dr. Julie Segre. NHGRI. "Microbial genomics: Tracking Multi-drug resistant bacterial ... The Importance of Scale in Drosophila Evolutionary Genomics". March 11 - Dr. Trudy Mackay. William Neal Reynolds and ... "Host determinants of response to HIV-1". May 19 - Dr. Katherine Friedman Vanderbilt University. 'Finding the right balance: ...
  http://www.gs.washington.edu/news/pastseminars.htm
*  Scientist Search Results | HHMI.org
Evolutionary Biology (3) Apply Evolutionary Biology filter *Experimental Evolutionary Biology (1) Apply Experimental ... Sex Chromosomes and Sex Differences Whitehead Institute for Biomedical Research * Richard D. Palmiter, PhD Investigator ... Genomics (39) Apply Genomics filter *Inflammation (1) Apply Inflammation filter *Innate Immunity (2) Apply Innate Immunity ...
  http://www.hhmi.org/scientists/browse?kw=&sort_by=field_scientist_last_name&sort_order=ASC&field_scientist_classification%255B0%255D=17367&order=field_scientist_academic_institu&sort=asc&items_per_page=96&field_scientist_classification%5B0%5D=17367&field_scientific_disciplines%5B1%5D=17539
*  Frontiers | QTL Analysis of Type I and Type IIA Fibers in Soleus Muscle in a Cross between LG/J and SM/J Mouse Strains |...
... and the sex effect was greater in LG/J strain (strain-by-sex interaction, P,0.001). The cross-sectional area (CSA) did not ... Three significant QTL affecting CSA for type I and type IIA fibers mapped to chromosomes 1, 6 and 11 and three suggestive QTL ... for percentage of type I fibers to chromosomes 2, 3, and 4. Within each significant QTL, regions of conserved synteny were also ... are important determinants of functional characteristics of skeletal muscle, and of the quality of meat in livestock. Genetic ...
  https://www.frontiersin.org/articles/10.3389/fgene.2011.00099/full
*  Pathogen emergence in agro-ecosystems | Philosophical Transactions of the Royal Society B: Biological Sciences
2014 Sex or no sex: evolutionary adaptation occurs regardless. Bioessays 36, 335-345. (doi:10.1002/bies.201300155). ... 2010 Comparative genomics reveals mobile pathogenicity chromosomes in Fusarium. Nature 464, 367-373. (doi:10.1038/nature08850) ... Human-mediated spread through trade and travel also plays a critical role in the global dissemination of many plant pathogens, ... Menardo and co-workers applied a comparative transcriptome approach to identify virulence determinants in B.g. triticale. B.g. ...
  http://rstb.royalsocietypublishing.org/content/371/1709/20160026
*  A genetic method for dating ancient genomes provides a direct estimate of human generation interval in the last 45,000 years |...
2014) Determinants of mutation rate variation in the human germline. Annu Rev Genomics Hum Genet 15:47-70. ... 2015) Life history effects on the molecular clock of autosomes and sex chromosomes. Proc Natl Acad Sci USA 113(6):1588-1593. ... Ancient DNA analyses have transformed research into human evolutionary history, making it possible to directly observe genetic ... Evidence for a faster evolutionary rate of mtDNA lineages than Y chromosomes. Am J Hum Genet 72(6):1370-1388. ...
  http://www.pnas.org/content/113/20/5652
*  HHMI Scientists Search Results | Howard Hughes Medical Institute (HHMI)
The Impact of Human Evolutionary History on Biology and Disease Harvard Medical School Boston, MA ... Sex Chromosomes and Sex Differences Whitehead Institute for Biomedical Research Cambridge, MA ... Cancer Genomics Dana-Farber Cancer Institute Boston, MA Paul Modrich, PhD Investigator DNA Mismatch Repair and Genetic ... Molecular Determinants of Aortic Aneurysm and Other Manifestations of Connective Tissue Disorders The Johns Hopkins University ...
  http://www.hhmi.org/scientists/browse?kw=&sort_by=field_scientist_last_name&sort_order=ASC&field_scientist_classification%25255B0%25255D=17370&order=field_scientist_academic_institu&sort=asc&items_per_page=50&field_scientist_classification%5B0%5D=17367&field_scientific_disciplines%5B1%5D=17539
*  Scientists map sex chromosome evolution in pathogenic fungi - Scienmag: Latest Science and Health News
But in each of these lineages, there are multiple evolutionary events that have occurred, and you can use genomics to turn back ... According to their model, multiple translocations deposited the two sex determinants on the same chromosome, with a centromere ... essentially mimicking the human X or Y chromosome. ... on the sex chromosomes. In humans, those chromosomes go by the ... Scientists have been studying the evolution of sex chromosomes for more than a century. In the 1960's, Japanese-American ...
  https://scienmag.com/scientists-map-sex-chromosome-evolution-in-pathogenic-fungi/
*  HHMI Scientists Search Results | Howard Hughes Medical Institute (HHMI)
The Impact of Human Evolutionary History on Biology and Disease Harvard Medical School Boston, MA ... Sex Chromosomes and Sex Differences Whitehead Institute for Biomedical Research Cambridge, MA ... Genomics Education Partnership: Bringing Genomics Research into Undergraduate Biology Washington University in St. Louis St. ... Molecular Determinants of Aortic Aneurysm and Other Manifestations of Connective Tissue Disorders The Johns Hopkins University ...
  http://www.hhmi.org/scientists/browse?kw=&sort_by=field_scientist_last_name&sort_order=ASC&AxisPHP=a8fd3b9d1a7aae945bbad927df6117a4&qt-scientist_search_page_browse_opt=0&items_per_page=96&field_scientific_disciplines%5B0%5D=17539
*  Marais Gabriel -UMR CNRS 5558 Laboratoire de Biométrie et Biologie Évolutive
Footprints of Inversions at Present and Past Pseudoautosomal Boundaries in Human Sex Chromosomes, Genome Biology and Evolution ... Bioinformatics, Phylogeny and Evolutionary Genomics Group *Baobab Group *Sex and Evolution Group ... Hill-Robertson interference is a minor determinant of variations in codon bias across Drosophila melanogaster and ... Sex gap in aging and longevity: can sex chromosomes play a role?, Biology of sex differences, vol. 9 pp.33-33.. Marais GAB, ...
  http://lbbe.univ-lyon1.fr/-Marais-Gabriel-.html?lang=en
*  Migration of mitochondrial DNA in the nuclear genome of colorectal adenocarcinoma | Genome Medicine | Full Text
Our study also reveals sex-based differences in frequency of NUMT occurrence and that NUMT in blood reflects NUMT in tumors, ... We identify YME1L1 as the first NUMT suppressor gene in human and demonstrate that inactivation of YME1L1 induces migration of ... We identified YME1L1, a human homolog of yeast YME1 (yeast mitochondrial DNA escape 1) to be frequently mutated in colorectal ... via the Cancer Genomics Hub, using the GeneTorrent file acquisition tool. Data were analyzed to determine NUMT proportion and ...
  https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-017-0420-6
*  Plenary & Platform Session Listing | 2014 Drosophila Research Conference
Frequent sex chromosome transitions in Dipterans. Beatriz Vicoso, Doris Bachtrog. UC Berkeley, Berkeley, CA. 33 - 8:45. Female- ... Maternal Haploid, the Drosophila ortholog of human Spartan, is required for the integrity of paternal chromosomes at ... Genomics and the molecular basis of hybrid incompatibilities. Nitin Phadnis1, Emily Baker2, Jacob Kitzman3, Kimberly Frizzell1 ... Selective and demographic determinants of latitudinal variation in allele frequency in North American Drosophila melanogaster. ...
  http://www.genetics-gsa.org/drosophila/2014/pages/sessionlisting.shtml
*  Marais Gabriel -UMR CNRS 5558 Laboratoire de Biométrie et Biologie Évolutive
Footprints of Inversions at Present and Past Pseudoautosomal Boundaries in Human Sex Chromosomes, Genome Biology and Evolution ... 2002 : PhD in "Evolutionary Genomics", Univ. Lyon 1. French-relevant CV information : HDR (2009), Moniteur (1999-2002), Agrégé ... Hill-Robertson interference is a minor determinant of variations in codon bias across Drosophila melanogaster and ... Sex uncovered: the evolutionary biology of reproductive systems, Journal of evolutionary biology, vol. 27 pp.1287-91.. Kafer J ...
  http://lbbe.univ-lyon1.fr/-Marais-Gabriel-.html
*  ASMscience | Sex and the Imperfect Fu
... feature of the eukaryotic kingdom with the many benefits of sex in generating genetic diversity as substrates for evolutionary ... also allows the repair of random epigenetic or conventional genetic damage by recombination with homologous chromosomes and can ... Molecular markers reveal cryptic sex in the human pathogen Coccidioides immitis . Proc Natl Acad Sci USA 93 : 770-773.[CrossRef ... Genomics reveals sexual secrets of Aspergillus . Microbiology 149 : 2301-2303.[CrossRef] [PubMed] ...
  http://www.asmscience.org/content/book/10.1128/9781555819583.chap9
*  Holobionts as Units of Selection and a Model of Their Population Dynamics and Evolution | SpringerLink
Leclercq S, Thézé J, Chebbi MA et al (2016) Birth of a W sex chromosome by horizontal transfer of Wolbachia bacterial symbiont ... Ley RE, Peterson DA, Gordon JI (2006) Ecological and evolutionary forces shaping microbial diversity in the human intestine. ... Rand DM, Hane RA, Fry AJ (2004) Cytonuclear coevolution: the genomics of cooperation. Trends Ecol Evol 19:645-653CrossRefGoogle ... MacDonald SJ, Thomas GH, Douglas AE (2011) Genetic and metabolic determinants of nutritional phenotype in an insect-bacterial ...
  https://link.springer.com/article/10.1007%2Fs13752-017-0287-1
*  ASMscience | Sex and the Imperfect Fungi
Estimating the spontaneous mutation rate of loss of sex in the human pathogenic fungus Cryptococcus neoformans. Genetics 162: ... In Heitman J, Kronstad JW, Taylor JW, Casselton LA (ed), Sex in Fungi: Molecular Determination and Evolutionary Implications. ... ENVOY is a major determinant in regulation of sexual development in Hypocrea jecorina (Trichoderma reesei). Eukaryot Cell 11: ... Functional genomics provide new insights into regulation of morphogenesis and secondary metabolism in the industrial penicillin ...
  http://www.asmscience.org/content/journal/microbiolspec/10.1128/microbiolspec.FUNK-0043-2017
*  Sex determination strategies in 2012: towards a common regulatory model? | Reproductive Biology and Endocrinology | Full Text
Both of the latter have developed a variety of sex-specific/sex-related genes, which ultimately form a complete chromosome pair ... Although the evolutionary origin of sex remains controversial, there is little doubt that it has developed as a process of ... sex chromosomes/gonosomes). Interestingly, combinations of environmental and genetic mechanisms have been described among ... a central role of sex steroid control as a prerequisite for ultimately normal sex differentiation. Studies in invertebrates ...
  https://rbej.biomedcentral.com/articles/10.1186/1477-7827-10-13
*  Systems Genetics of Complex Traits in Drosophila melanogaster
Mapping determinants of human gene expression by regional and genome-wide association. Nature. 2005;437:1365-1369. [PMC free ... For the analyses by sex, H2 = σL 2/(σL 2 + σE 2). We estimated cross-trait (cross-sex) genetic correlations as rG = covij/σiσj ... Of flies and man: Drosophila as a model for human complex traits. Ann. Rev. Genomics Hum. Genetics. 2006;7:339-367. [PubMed] ... We found differences in overall transcript abundance among the chromosomes for both sexes (P , 0.0001), with chromosome 4 ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2752214/?lang=en-ca
*  ISEMPH 2017 Program | The Evolution and Medicine Review
Escherichia coli evolution Evolutionary biology evolutionary medicine gene Genetics genome genotype History HIV-1 human ... 14:30-14:50 Sexual antagonism drives the evolution of the guppy sex chromosomes Alison Wright, University of Sheffield, ... 10:30-11:00 Determinants of recombination activity-the alternative hotspot view Irene Tiemann-Boege, Johannes Kepler University ... 10:30-11:00 Comparative genomics, the anomaly zone, and the phylogeny of palaeognathous birds ...
  https://evmedreview.com/5091-2/?shared=email&msg=fail
*  NYS Higher Education Services Corporation - Approved STEM Programs of Study
... genomics, evolutionary ecology, natural adaptation and hybridization, geographic differentiation, life history and life cycle ... Human/Medical Genetics.. A program that focuses on the scientific study of human genetics from the standpoint of medical ... A program that focuses on the scientific study of the genetic determinants of susceptibility to external pollutants and poisons ... Includes instruction in Mendelian genetics, mechanisms of gene regulation, chromosome structure and replication, epigenetic ...
  https://www.hesc.ny.gov/pay-for-college/financial-aid/types-of-financial-aid/nys-grants-scholarships-awards/nys-science-technology-engineering-and-mathematics-stem-incentive-program/stem-approved-academic-program-listing
*  Items by Hurst, Laurence - Opus
Local similarity in evolutionary rates extends over whole chromosomes in human-rodent and mouse-rat comparisons: Implications ... Evolutionary genomics - Sex and the X. Nature. , 411 (6834), pp. 149-150. ... Determinants of the usage of splice-associated cis-motifs predict the distribution of human pathogenic SNPs. Molecular Biology ... Evidence that the human X chromosome is enriched for male-specific but not female-specific genes. Molecular Biology and ...
  http://opus.bath.ac.uk/view/person_id/611.date.html
*  Dienekes' Anthropology Blog: 09/2014
Annual Review of Genomics and Human Genetics Vol. 15: 47-70 (Volume publication date August 2014). Determinants of Mutation ... in an intragenomic conflict with regions of similar function on the Y chromosome for transmission of sex chromosomes to the ... After decades during which estimates were based on indirect approaches, notably on inferences from evolutionary patterns, it is ... The human X chromosome is the target of megabase wide selective sweeps associated with multi-copy genes expressed in male ...
  http://dienekes.blogspot.no/2014/09/