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*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
PERK regulates the proliferation and development of insulin-secreting beta-cell tumors in the endocrine pancreas of mice. ... this decrement develops from both an inability of beta cells to secrete insulin appropriately and the destruction of beta cells ... Pathology of pancreatic sections is intended to characterize both exocrine, ductular, and endocrine components. The exocrine ... Optimal immunofluoresent staining results can be achieved in multiple tissue types, including pancreas, skin, gut, liver, ...
  https://www.jove.com/visualize/abstract/19956728/perk-regulates-proliferation-development-insulin-secreting-beta-cell
*  Plus it
... or slightly decreased insulin levels; a failure of the β cell to overcome insulin resistance, and an inability of the liver to ... The former, termed T1DM, is associated with undetectable insulin levels due to autoimmune-mediated destruction of the β cells ... T3cDM observed in chronic pancreatitis is associated with decreased insulin levels due to the loss of insulin-secreting β cells ... whether loss of β-cell mass in chronic pancreatitis is caused by exosomes targeting the endocrine islets; whether exosome- ...
  http://clincancerres.aacrjournals.org/content/21/7/1508
*  Neurosecretory cell | definition of neurosecretory cell by Medical dictionary
What is neurosecretory cell? Meaning of neurosecretory cell medical term. What does neurosecretory cell mean? ... Looking for online definition of neurosecretory cell in the Medical Dictionary? neurosecretory cell explanation free. ... basophilic cell. Basophil.. beta cell. 1. Any of the insulin-secreting cells of the pancreas that constitute the bulk of the ... somatic cells the cells of the somatoplasm; undifferentiated body cells.. somatostatin cells endocrine cells of the oxyntic and ...
  https://medical-dictionary.thefreedictionary.com/neurosecretory+cell
*  Segmented cell | definition of segmented cell by Medical dictionary
... segmented cell explanation free. What is segmented cell? Meaning of segmented cell medical term. What does segmented cell mean? ... Looking for online definition of segmented cell in the Medical Dictionary? ... basophilic cell. Basophil.. beta cell. 1. Any of the insulin-secreting cells of the pancreas that constitute the bulk of the ... liver cell. Hepatocyte.. lutein cell. A cell of the corpus luteum of the ovary that contains fatty yellowish granules. ...
  https://medical-dictionary.thefreedictionary.com/segmented+cell
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... this decrement develops from both an inability of beta cells to secrete insulin appropriately and the destruction of beta cells ... Pathology of pancreatic sections is intended to characterize both exocrine, ductular, and endocrine components. The exocrine ... the effect of specific transcellular interactions on the insulin secreting capacity and responsiveness of beta cells is ... In this system, mouse fetal liver TER119 (mature erythroid cell marker) negative erythroblasts were purified and transduced ...
  https://www.jove.com/visualize/abstract/23861885/a-synthetic-model-human-beta-thalassemia-erythropoiesis-using-cd34
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... this decrement develops from both an inability of beta cells to secrete insulin appropriately and the destruction of beta cells ... The β-cells of the pancreatic islets of Langerhans are responsible for appropriately secreting insulin in response to elevated ... Medicine, Issue 57, Glucose, insulin, clamp, mice, insulin resistance, diabetes, liver, muscle, conscious, restraint-free, non- ... Medicine, Issue 87, human fetal pancreas, islet cell cluster (ICC), transplantation, immunofluorescence, endocrine cell ...
  https://www.jove.com/visualize/abstract/22479612/isosteviol-has-beneficial-effects-on-palmitate-induced-cell
*  Haematids | definition of Haematids by Medical dictionary
basophilic cell. Basophil.. beta cell. 1. Any of the insulin-secreting cells of the pancreas that constitute the bulk of the ... liver cell. Hepatocyte.. lutein cell. A cell of the corpus luteum of the ovary that contains fatty yellowish granules. ... postganglionic cell. Postganglionic neuron.. PP cell. An enteroendocrine endocrine cell found in the pancreatic islets that ... Mucous cells and serous cells are the two varieties of secretory cells found in exocrine glands. ...
  http://medical-dictionary.thefreedictionary.com/Haematids
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
Type 1 diabetes mellitus (T1DM) is an autoimmune disease caused by immune-mediated destruction of insulin-secreting ? cells of ... Medicine, Issue 87, human fetal pancreas, islet cell cluster (ICC), transplantation, immunofluorescence, endocrine cell ... including exocrine, ductal, and other hormone producing cells. ... delivered via infection of the mouse liver with an adenoviral ... this decrement develops from both an inability of beta cells to secrete insulin appropriately and the destruction of beta cells ...
  https://www.jove.com/visualize/abstract/24594640/ex-vivo-expanded-human-regulatory-t-cells-delay-islet-allograft
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... this decrement develops from both an inability of beta cells to secrete insulin appropriately and the destruction of beta cells ... The β-cells of the pancreatic islets of Langerhans are responsible for appropriately secreting insulin in response to elevated ... Medicine, Issue 87, human fetal pancreas, islet cell cluster (ICC), transplantation, immunofluorescence, endocrine cell ... including exocrine, ductal, and other hormone producing cells. ... liver, retina, cochlea and vasculature. In experimental ...
  https://www.jove.com/visualize/abstract/24069189/differential-protective-effects-exenatide-an-agonist-glp-1-receptor
*  Reg3α Overexpression Protects Pancreatic β Cells from Cytokine-Induced Damage and Improves Islet Transplant Outcome | Springer...
Cell Culture, Cell Viability and Reactive Oxygen Species (ROS) Detection. Rat insulin-secreting cell line INS-1 (passage 15-30 ... growing evidence links Reg3α and other Reg proteins to the regeneration of not only exocrine but also of the endocrine tissue ... Meng ZX, et al. (2009) Activation of liver X receptors inhibits pancreatic islet beta cell proliferation through cell cycle ... and IFN-gamma mark beta cells for Fas-dependent destruction by diabetogenic CD4(+) T lymphocytes. J. Clin. Invest. 105:459-68. ...
  https://rd.springer.com/article/10.2119%2Fmolmed.2014.00104
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... and Gem over-expression inhibits insulin release in insulin-secreting Min6 cells. The aim of this study was to explore the role ... this decrement develops from both an inability of beta cells to secrete insulin appropriately and the destruction of beta cells ... Medicine, Issue 57, Glucose, insulin, clamp, mice, insulin resistance, diabetes, liver, muscle, conscious, restraint-free, non- ... Medicine, Issue 87, human fetal pancreas, islet cell cluster (ICC), transplantation, immunofluorescence, endocrine cell ...
  https://www.jove.com/visualize/abstract/22761801/mice-deficient-gem-gtpase-show-abnormal-glucose-homeostasis-due-to
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
The pancreatic islet is a unique micro-organ composed of several hormone secreting endocrine cells such as beta-cells (insulin ... this decrement develops from both an inability of beta cells to secrete insulin appropriately and the destruction of beta cells ... Pathology of pancreatic sections is intended to characterize both exocrine, ductular, and endocrine components. The exocrine ... Medicine, Issue 57, Glucose, insulin, clamp, mice, insulin resistance, diabetes, liver, muscle, conscious, restraint-free, non- ...
  https://www.jove.com/visualize/abstract/23077547/glucose-decouples-intracellular-ca2-activity-from-glucagon-secretion
*  Molecular Targeting of Pancreatic Disorders | SpringerLink
2000Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice ... Pourr, PM, Schmied, B 1999The link between exocrine pancreatic cancer and the endocrine pancreasInt. J. Pancreatol.257787PubMed ... N 1994Production of interleukin 10 by islet cells accelerates immune-mediated destruction of beta cells in nonobese diabetic ... 2000The dominant negative H-ras mutant, N116Y, suppresses growth of metastatic human pancreatic cancer cells in the liver of ...
  https://link.springer.com/article/10.1007%2Fs00268-004-7821-6
*  Patent US20030119736 - Methods for improving islet signaling in diabetes mellitus and for its ... - Google Patents
... to cause differentiation of pancreatic epithelial cells into insulin producing β-cells, to improve muscle sensitivity to ... in particular in the pancreatic tissue can also facilitate differentiation and regeneration of the β-cells already present that ... insulin and other weight control efforts by the chronic oral administration of a DP IV-inhibitor. The administration causes the ... to increase the relative insulin producing performance of endogenous pancreatic β-cells, ...
  http://www.google.com/patents/US20030119736?dq=5,646,839
*  Cellphone | definition of cellphone by Medical dictionary
basophilic cell. Basophil.. beta cell. 1. Any of the insulin-secreting cells of the pancreas that constitute the bulk of the ... somatic cells the cells of the somatoplasm; undifferentiated body cells.. somatostatin cells endocrine cells of the oxyntic and ... fat-storing cell of liver lipid-accumulating, stellate cells located in the perisinusoidal space of the liver. ... Mucous cells and serous cells are the two varieties of secretory cells found in exocrine glands. ...
  http://medical-dictionary.thefreedictionary.com/cellphone
*  Insulin-dependent diabetes mellitus | definition of insulin-dependent diabetes mellitus by Medical dictionary
What is insulin-dependent diabetes mellitus? Meaning of insulin-dependent diabetes mellitus medical term. What does insulin- ... Looking for online definition of insulin-dependent diabetes mellitus in the Medical Dictionary? insulin-dependent diabetes ... Type 1 DM is caused by autoimmune destruction of the insulin-secreting beta cells of the pancreas. The loss of these cells ... Diabetes associated with destruction of the exocrine and endocrine functions of the pancreas, such as occurs in chronic or ...
  https://medical-dictionary.thefreedictionary.com/insulin-dependent+diabetes+mellitus
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
Type 1 diabetes is caused by T cell-mediated autoimmune destruction of insulin-producing cells in the pancreas. Until now ... Pathology of pancreatic sections is intended to characterize both exocrine, ductular, and endocrine components. The exocrine ... T cell subsets, B cells, natural killer (NK) and NKT cells. Intravital microscopy of the liver for monitoring immune cell ... The β-cells of the pancreatic islets of Langerhans are responsible for appropriately secreting insulin in response to elevated ...
  https://www.jove.com/visualize/abstract/26075596/the-identification-novel-protein-protein-interactions-liver-that
*  DM | definition of DM by Medical dictionary
Type 1 DM is caused by autoimmune destruction of the insulin-secreting beta cells of the pancreas. The loss of these cells ... Diabetes associated with destruction of the exocrine and endocrine functions of the pancreas, such as occurs in chronic or ... the cells in the pancreas that make insulin) as well as a decrease in sensitivity of the liver and muscles to the actions of ... Type 1 DM is caused by autoimmune destruction of the insulin-secreting beta cells of the pancreas. The loss of these cells ...
  http://medical-dictionary.thefreedictionary.com/DM