Effects of Selective Checkpoint Kinase 1 Inhibition on Cytarabine Cytotoxicity in Acute Myelogenous Leukemia Cells In Vitro |...
... including diminished cytarabine import, increased cytarabine degradation, decreased formation or retention of cytarabine ... F, effects of 10 nmol/L cytarabine (light gray bars), 100 nmol/L SCH 900776 (white bars), or 10 nmol/L cytarabine + 100 nmol/L ... SCH 900776 inhibits Chk1, abrogates cytarabine-induced cell-cycle arrest, and enhances cytarabine-induced killing of human AML ... Importantly, 9 of 10 samples without prior cytarabine exposure were sensitized to cytarabine by addition of SCH 900776. In ...http://clincancerres.aacrjournals.org/content/18/19/5364?rss=1
Donor Stem Cell Transplant in Treating Patients With High Risk Acute Myeloid Leukemia - Full Text View - ClinicalTrials.gov
To compare in preliminary manner the clinical outcomes of cytarabine and HMMACT in patients with high risk AML as measured by ... Cytarabine. Mitoxantrone. Antimetabolites, Antineoplastic. Antimetabolites. Molecular Mechanisms of Pharmacological Action. ... To further evaluate the safety outcomes of induction and consolidation of cytarabine and HMMACT in terms of serious infections ... I. To obtain preliminary estimates of clinical outcome following cytarabine based chemotherapy and HMMACT in patients with high ...https://clinicaltrials.gov/ct2/show/NCT01801046?cond=%22Acute+non+lymphoblastic+leukemia%22&rank=4
High-Dose Sequential Chemoimmunotherapy for B-Cell Lymphomas With Central Nervous System Involvement - Full Text View -...
Two courses of methotrexate 3.5 g/mq day 1 and cytarabine 2 g/mq twice a day, for two days, Rituximab 375 mg/mq days 3 & 11 and ... Two courses of methotrexate 3.5 g/mq day 1 and cytarabine 2 g/mq twice a day, for two days, Rituximab 375 mg/mq days 3 & 11 and ... Cytarabine. Antineoplastic Agents. Immunologic Factors. Physiological Effects of Drugs. Antirheumatic Agents. Antimetabolites, ... Cytarabine 2 g/mq twice a day for 4 days, Rituximab 375 mg/m2 and Reinfusion of stem cells (Phase III), etoposide 2 g/mq, ...https://clinicaltrials.gov/ct2/show/NCT00801216
3-AP and High-Dose Cytarabine in Treating Patients With Advanced Hematologic Malignancies - Full Text View - ClinicalTrials.gov
Experimental: Treatment (cytarabine and triapine) Patients receive high-dose cytarabine IV over 2 hours on days 1-5 and ... 3-AP may help cytarabine kill more cancer cells by making them more sensitive to the drug. This phase I trial is studying the ... Patients receive high-dose cytarabine IV over 2 hours on days 1-5 and 3-AP (Triapine) IV over 2 hours on days 2-5. Treatment ... Drug Information available for: Cytarabine Genetic and Rare Diseases Information Center resources: Myeloid Leukemia Acute ...https://clinicaltrials.gov/ct2/show/NCT00077181
AML96 - Risk-Adapted and Randomized Postremission-Therapy for Adult Acute Myeloid Leukemia Patients - Full Text View -...
Furthermore it randomizes patients between intermediate-dose Cytarabine vs high-dose Cytarabine within the first postremission- ... Furthermore it randomizes patients between intermediate-dose Cytarabine vs high-dose Cytarabine within the first postremission- ... Drug Information available for: Cytarabine Genetic and Rare Diseases Information Center resources: Myeloid Leukemia Acute ... cytarabine postremission dosage. risk adapted treatment strategy. allogeneic stem cell transplantation. autologous stem cell ...https://clinicaltrials.gov/ct2/show/NCT00180115
Phase 2 Study of 5 Days Azacytidine Priming Prior to Fludarabine, Cytarabine and Granulocyte-Colony Stimulating Factor (G-CSF)...
... cytarabine, and G-CSF for the treatment of relapsed or ... Cytarabine and Granulocyte-Colony Stimulating Factor (G-CSF) ... Phase 2 Study of 5 Days Azacytidine Priming Prior to Fludarabine, Cytarabine and Granulocyte-Colony Stimulating Factor (G-CSF) ...http://adisinsight.springer.com/trials/700250876?error=cookies_not_supported&code=13e173a6-c299-4251-be64-c96493a14b56
Paper: Phase II Study of High Dose Cytarabine Followed By Pembrolizumab in Relapsed/Refractory Acute Myeloid Leukemia (AML)
1349 Phase II Study of High Dose Cytarabine Followed By Pembrolizumab in Relapsed/Refractory Acute Myeloid Leukemia (AML) Acute ... Blood [Abstract] 2015). We hypothesized that administration of pembrolizumab after high dose cytarabine (HiDAC) salvage ...https://ash.confex.com/ash/2017/webprogram/Paper100048.html
Trebananib With or Without Low-Dose Cytarabine in Treating Patients With Acute Myeloid Leukemia - Full Text View -...
Experimental: Arm B (trebananib, cytarabine) Patients receive trebananib as in Arm A. Patients also receive cytarabine SC BID ... Trebananib With or Without Low-Dose Cytarabine in Treating Patients With Acute Myeloid Leukemia. This study has been completed ... Drug Information available for: Cytarabine Genetic and Rare Diseases Information Center resources: Myeloid Leukemia Acute ... Drugs used in chemotherapy, such as cytarabine, work in different ways to stop the growth of cancer cells, either by killing ...https://clinicaltrials.gov/ct2/show/NCT01555268?cond=%22Acute+myeloblastic+leukemia+without+maturation%22&rank=19
A Phase 1/2 Study of Venetoclax in Combination With Low-Dose Cytarabine in Treatment-Naive Subjects With Acute Myelogenous...
A Phase 1/2 Study of Venetoclax in Combination With Low-Dose Cytarabine in Treatment-Naive Subjects With Acute Myelogenous ... A Phase 1/2 Study of Venetoclax in Combination With Low-Dose Cytarabine in Treatment-Naive Subjects With Acute Myelogenous ... in combination with low dose cytarabine (LDAC) for elderly patients with previously untreated AML who are ineligible for ...http://adisinsight.springer.com/trials/700251280?error=cookies_not_supported&code=bda4afc7-5676-4bb1-9cb0-29c683e53201
Cytarabine Manufacturers, Suppliers & Exporters in India
Contact to Cytarabine Exporters in India, Cytarabine Wholesalers, Cytarabine Distributors and Traders from India. ... Cytarabine 500mg, Docetaxel 80mg, CYTARABINE, Dacarbazine 500mg, Cytarabine 1000mg, Cisplatin 10mg, Bortezumib 3.5mg, ... Deals in Succinylcholine chloride, Etoricoxib, Trenbolone Acetate, Vitamin B2 Riboflavin, cytarabine, Vitamin B5 Calcium ... cytarabine, Irinotecan Hcl, Mitoxantrone Hcl, Oxaliplatin, Generic Medicines, Pharmaceutical Chemical, Nedaplatin... ...http://www.indianyellowpages.com/india/manufacturers/c/cytarabine.htm
Oxaliplatin, Fludarabine, Cytarabine, and Rituximab in Patients With Richter's Transformation and Leukemias - Tabular View...
Drug: Cytarabine Cytarabine 500 mg/m^2 daily IV, 2-hour infusion starting 4 hours after first fludarabine dose is started, on ... However, fludarabine and cytarabine will be given daily for 2 days to the first 3 participants, daily for 3 days to the next 3 ... Fludarabine and Cytarabine Dose Level 1: Days 2-3 (2 Days); Dose Level 2: Days 2-4 (3 Days); and Dose 3: Days 2-5 (4 Days). MTD ... Cytarabine 500 mg/m^2 daily IV, 2-hour infusion starting 4 hours after first fludarabine dose started, on days 2-3, 2-4, or 2-5 ...https://clinicaltrials.gov/ct2/show/record/NCT00472849
Cytarabine Advanced Patient Information - Drugs.com
Detailed drug Information for cytarabine. Includes common brand names, drug descriptions, warnings, side effects and dosing ... After treatment with cytarabine has ended, normal hair growth should return.. After you stop using cytarabine, it may still ... Proper Use of cytarabine. cytarabine is sometimes given together with certain other medicines. If you are using a combination ... Before you begin treatment with cytarabine, you and your doctor should talk about the good cytarabine will do as well as the ...https://www.drugs.com/cons/cytarabine.html
Cytarabine - Information and support - Macmillan Cancer Support
Cytarabine is a chemotherapy drug used to treat acute myeloid leukaemia (AML). It may also be used to treat other types of ... How cytarabine is given. You will have cytarabine in the chemotherapy day unit or during a stay in hospital. A chemotherapy ... Less common side effects of cytarabine. Effects on the lungs. Cytarabine can cause changes to the lungs. These are more common ... Common side effects of cytarabine. Risk of infection. Cytarabine can reduce the number of white blood cells in your blood. This ...https://www.macmillan.org.uk/information-and-support/treating/chemotherapy/drugs-and-combination-regimens/individual-drugs/cytarabine.html
Daunorubicin and Cytarabine (Liposomal) Information - Drugs.com
Easy to read patient leaflet for Daunorubicin and Cytarabine (Liposomal). Includes indications, proper use, special ... Daunorubicin and Cytarabine (Liposomal). Generic Name: Daunorubicin and Cytarabine (Liposomal) (daw noe ROO bi sin & sye TARE a ... How do I store and/or throw out Daunorubicin and Cytarabine?. *If you need to store daunorubicin and cytarabine at home, talk ... How is this medicine (Daunorubicin and Cytarabine) best taken?. Use daunorubicin and cytarabine as ordered by your doctor. Read ...https://www.drugs.com/cdi/daunorubicin-and-cytarabine-liposomal.html
Cytarabine (Oral Route) Side Effects - Mayo Clinic
After treatment with cytarabine has ended, normal hair growth should return.. After you stop using this medicine, it may still ...https://www.mayoclinic.org/drugs-supplements/cytarabine-oral-route/side-effects/drg-20063270
Laracit (Cytarabine) Teva
Laracit information about active ingredients, pharmaceutical forms and doses by Teva, Laracit indications, usages and related health products listshttp://drugs-about.com/drugs-l/laracit.html
WARNINGS Only physicians experienced in cancer chemotherapy should use Cytarabine for Injection USP. For induction therapy, ... Cytarabine for Injection USP is available in vials containing 100 mg, 500mg, 1 g, and 2 g cytarabine. When necessary, the pH of ... sterile lyophilized cytarabine (1-b-D-Arabinofuranosylcytosine). Cytarabine is an odorless, white to off-white, crystalline ... Cytarabine is a synthetic nucleoside which differs from the normal nucleosides cytidine and deoxycytidine in that the sugar ...http://www.egeneralmedical.com/rxlist00000881.html
Cytarabine Crisis: Leukemia Drug Shortage Affecting Many Hospitals - ABC News
ABC News heard from dozens of medical centers on reported shortages of the leukemia drug cytarabine. While some hospitals ... Hospitals Where a Cytarabine Shortage Has Not Yet Affected Patients. University of Michigan, Ann Arbor, Mich. ... "Tufts Medical Center does have a shortage of cytarabine. I have been told that we are working with only 40 grams in stock as of ... Hospitals Where a Cytarabine Shortage Has Affected Patients. Johns Hopkins: Baltimore, Md. ...http://abcnews.go.com/Health/cytarabine-crisis-leukemia-drug-shortage-affecting-hospitals/story?id=13378283
Cytarabine facts, information, pictures | Encyclopedia.com articles about Cytarabine
Make research projects and school reports about Cytarabine easy with credible articles from our FREE, online encyclopedia and ... Cytarabine Gale Encyclopedia of Cancer COPYRIGHT 2002 The Gale Group Inc.. Cytarabine. Definition. Cytarabine (also known as ... High-dose cytarabine may be 2 to 3 grams per square meter of body surface area twice a day for three days. Cytarabine is also ... High doses of cytarabine may trigger what is known as cytarabine syndrome, which consists of fever, muscle ache, bone pain , ...https://www.encyclopedia.com/medicine/drugs/pharmacology/cytarabine
Cytarabine (Conventional): Pediatric Medication | Memorial Sloan Kettering Cancer Center
Cytarabine Injection; Cytosar. Warning. *This drug may have effects on the bone marrow. The bone marrow may not be able to make ...https://www.mskcc.org/cancer-care/patient-education/cytarabine-conventional-01
Cytarabine (Oral Route) Description and Brand Names - Mayo Clinic
Cytarabine belongs to the group of medicines called antimetabolites. It is used to treat some kinds of cancers of the blood. It ... Cytarabine interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells ... Before you begin treatment with cytarabine, you and your doctor should talk about the good this medicine will do as well as the ... Cytarabine is to be administered only by or under the immediate supervision of your doctor. ...https://www.mayoclinic.org/drugs-supplements/cytarabine-oral-route/description/drg-20063270
Cytarabine Injection (Cytarabine [sye-TAYR-a-been]) Drug / Medicine Information
... about Cytarabine Injection (Cytarabine [sye-TAYR-a-been]) intended for persons living in Australia. ... Cytarabine Injection is a clear solution in a plastic vial.. Ingredients Cytarabine Injection contains Cytarabine 20 mg/mL with ... What Cytarabine Injection is used for Cytarabine belongs to a group of medicines known as antineoplastics. It is used to treat ... How Cytarabine Injection works Cytarabine works by preventing the growth of cancer cells and eventually destroying them. It is ...https://www.news-medical.net/drugs/Cytarabine-Injection.aspx
CYTARABINE LIPOSOME - INJECTION (Depocyt) side effects, medical uses, and drug interactions.
Read more about the prescription drug CYTARABINE LIPOSOME - INJECTION. ... Consumer information about the medication CYTARABINE LIPOSOME - INJECTION (Depocyt), includes side effects, drug interactions, ... cytarabine liposome - injection, Depocyt. GENERIC NAME: CYTARABINE LIPOSOME - INJECTION (sye-TARE-ah-been lye-poe-SEW-mull). ... USES: Cytarabine liposome is a long-acting (sustained-release) chemotherapy drug used to treat cancer in the area around the ...https://www.medicinenet.com/cytarabine_liposome-injectable/article.htm
cytarabine - UNM Comprehensive Cancer Center
How is cytarabine typically given (administered)? Cytarabine may be administered intravenously (into a vein), subcutaneously ( ... What is the mechanism of action? Cytarabine belongs to a group of drugs called antimetabolites. Cytarabine produces its anti- ... Generic Name: Cytarabine (sigh-TARE-a-been), Ara-C, Arabinosylcytosine. Trade Name: Cytosar-U® ... What are the less common (occur in 10% to 29% of patients) side effects of treatment with cytarabine?. • Diarrhea. • Loss of ...http://cancer.unm.edu/2009/04/28/cytarabine/
Cytarabine by Novopharm - Pharmasave
Cytarabine fights cancer by preventing the growth of cancer cells, which eventually results in their destruction. Cytarabine is ... The recommended dose of cytarabine and how the cytarabine is used varies according to the specific condition being treated, the ... Anemia: Cytarabine may cause low levels of red blood cells. If you experience symptoms of reduced red blood cell count (anemia) ... Cytarabine is available as an intrathecal (into the space between the layers of tissue covering the brain and spinal cord) ...http://www.pharmasave.com/medications/cytarabine-by-novopharm/