*  COX1 / Cyclooxygenase 1抗体[EPR5866]|Abcam中国|Anti-COX1 / Cyclooxygenase 1抗体[EPR5866]
Cyclooxygenase 1兔单克隆抗体[EPR5866](ab109025)可与小鼠, 大鼠, 人样本反应并经WB, IP, IHC, Flow Cyt, ICC/IF实 ... Anti-COX1 / Cyclooxygenase 1 antibody [EPR5866] (Alexa Fluor® 488) (ab199027) *Anti-COX1 / Cyclooxygenase 1 antibody [EPR5866 ... Anti-COX1 / Cyclooxygenase 1 antibody [EPR5866] (Alexa Fluor® 405) (ab210434) *Anti-COX1 / Cyclooxygenase 1 antibody [EPR5866 ... Anti-COX1 / Cyclooxygenase 1 antibody [EPR5866] (HRP) (ab199203) *Anti-COX1 / Cyclooxygenase 1 antibody
  http://www.abcam.cn/cox1-cyclooxygenase-1-antibody-epr5866-ab109025.html
*  PTGS2 prostaglandin-endoperoxide synthase 2 [Homo sapiens (human)] - Gene - NCBI
HIV-1 Tat-induced cyclooxygenase (COX)-2 expression and prostaglandin E2 (PGE2) synthesis increase Leishmania growth in HIV-1- ... implying that COX-1 is not involved Title: Roles of 5-lipoxygenase and cyclooxygenase-2 in the biosynthesis of hemiketals E,sub ... Cyclooxygenase-2 expression and association with skin cancer: A meta-analysis based on Chinese patients. Shujiao L, et al. J ... Specific inhibitors of COX-2 and 5-LOX decreased formation of HKD2 and HKE2 Platelets did not form HKs from exogenous 5S- ...
  https://www.ncbi.nlm.nih.gov/gene?LinkName=pubmed_gene_rif&from_uid=17214885
*  Prostaglandin-endoperoxide synthase 2 - Wikipedia
Each monomer of the enzyme has a peroxidase and a PTGS (COX) active site. The PTGS (COX) enzymes catalyze the conversion of ... PTGS1 (COX-1) and PTGS2 (COX-2) are bifunctional enzymes that carry out two consecutive chemical reactions in spatially ... The tertiary and quaternary structures of PTGS1 (COX-1) and PTGS2 (COX-2) enzymes are almost identical. Each subunit has three ... Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit prostaglandin production by PTGS1 (COX-1) and PTGS2 (COX-2). NSAIDs ...
  https://en.wikipedia.org/wiki/Cyclooxygenase-2
*  COX-2 inhibitor - Wikipedia
Prostaglandins whose synthesis involves the cyclooxygenase-I enzyme, or COX-1, are responsible for maintenance and protection ... 170-fold more potent in inhibiting COX-1 than COX-2.[32] Studies of meloxicam 7.5 mg per day for 23 days find a level of ... "COX-2 Inhibitors and Cancer". Fact Sheet. United States National Cancer Institute. Archived from the original on May 9, 2008.. ... COX-2 up-regulation has also been linked to the phosphorylation and activation of the E3 ubiquitin ligase HDM2, a protein that ...
  https://en.wikipedia.org/wiki/COX_inhibitor
*  Cox-2 - Drugs.com
A list of US medications equivalent to Cox-2 is available on the Drugs.com website. ... Cox-2 is a medicine available in a number of countries worldwide. ... Cox-2 may be available in the countries listed below.. Ingredient matches for Cox-2. Celecoxib. Celecoxib is reported as an ...
  https://www.drugs.com/international/cox-2.html
*  Glycosylation regulates turnover of cyclooxygenase-2.
... Sevigny M.B., Li C.F., Alas M., Hughes-Fulford M. ... COS-1 cells transfected with the mutant gene were unable to express the 74kDa glycoform and were found to accumulate more COX-2 ... Cyclooxygenase-2 (COX-2) catalyzes the rate-limiting step in the prostanoid biosynthesis pathway, converting arachidonic acid ... Thus, COX-2 turnover appears to depend upon glycosylation of the 72kDa glycoform. ...
  http://www.uniprot.org/citations/17113084
*  Expression der Cyclooxygenase-2 im Mammakarzinom
Cyclooxygenases regulate the production of prostaglandins and play a role in tumor development and progression. COX-inhibitors ... In this study, we investigated the prognostic impact of expression of both COX-isoforms as well as the association of COX ... Diese wurden mittels immunhistochemischer Methoden auf beide COX-Isoenzyme untersucht. Eine erhöhte COX-2 Expression wurde in ... The expression of COX-1 and -2 was determined by immunohistochemistry retrospectivly in a cohort of 221 women. An elevated ...
  https://edoc.hu-berlin.de/handle/18452/15897
*  FDA calls for evaluation of Cox-2 inhibitors - MarketWatch
LOS ANGELES (CBS.MW) -- The U.S. Food and Drug Administration has called for evaluation of Cox-2 inhibitors such as Celebrex ...
  https://www.marketwatch.com/story/fda-calls-for-evaluation-of-cox-2-inhibitors
*  Natural Sheep COX2 / Cyclooxygenase 2 protein (ab81696)
Cyclooxygenase 2 protein. Ab81696 is a full length protein produced in Nativesyntheticaly and has been validated in WB. Abcam… ... References for Natural Sheep COX2 / Cyclooxygenase 2 protein (ab81696). ab81696 has not yet been referenced specifically in any ... Natural Sheep COX2 / Cyclooxygenase 2 protein. See all COX2 / Cyclooxygenase 2 proteins and peptides. ...
  http://www.abcam.com/natural-sheep-cox2-cyclooxygenase-2-protein-ab81696.html
*  Efficacy and safety of COX 2 inhibitors | The BMJ
Two large pivotal trials have been published, in which the efficacy and safety of the COX 2 inhibitors celecoxib and rofecoxib ... Efficacy and safety of COX 2 inhibitors New data are encouraging but the risk:benefit ratio remains unclear ... with more specific inhibitory effects on cyclo-oxygenase 2 (COX 2) pathways, promised equivalent efficacy with greater safety ... Efficacy and safety of COX 2 inhibitors. BMJ 2002; 325 doi: https://doi.org/10.1136/bmj.325.7365.607 (Published 21 September ...
  http://www.bmj.com/content/325/7365/607
*  Cox-2 inhibitor | Define Cox-2 inhibitor at Dictionary.com
Cox-2 inhibitor definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation. Look it up ... cox-2 inhibitor in Medicine Expand. COX-2 inhibitor n. Any of a class of nonsteroidal anti-inflammatory drugs thought to have ...
  http://www.dictionary.com/browse/cox-2-inhibitor
*  COX-2 inhibitors and gastroduodenal toxicity: Major clinical trials
Two related isoforms of the cyclo-oxygenase (COX) enzyme have been described: COX-1 (PGHS-1) and COX-2 (PGHS-2). COX-1 is ... COX-2 inhibitors and gastroduodenal toxicity: Major clinical trials. Author. Mark Feldman, MD, MACP, AGAF, FACG. Mark Feldman, ... COX-2 inhibitors. Lancet 1999; 353:307.. *Simon LS, Weaver AL, Graham DY, et al. Anti-inflammatory and upper gastrointestinal ... Other COX-2 inhibitors are available in some countries. Parecoxib is a prodrug that is converted to valdecoxib. Etoricoxib and ...
  http://www.uptodate.com/contents/pulse-oximetry-in-adults/abstract/10
*  Tobacco smoke increases the levels of Cox 2.
... tobacco smoke have been linked with the rising levels of the chemical compound called Cox 2. ... Scientists of the study had found out higher levels of Cox 2 in the oral mucosal cells of the mouth lining of the smokers than ... Cox 2 is a cellular protein that had been related to onset and development of cancer. The tobacco smoke had also been related ... tobacco smoke have been linked with the rising levels of the chemical compound called Cox 2. ...
  http://www.medindia.net/news/view_news_main.asp?x=3525
*  Cyclooxygenase-2 in Human and Experimental Ischemic Proliferative Retinopathy | Circulation
The impact of COX inhibition on neovascularization was tested using specific COX-2 (APHS and etodolac) and COX-1 (SC-560) ... Cyclooxygenase (COX)-2 is also an immediate-early gene product of inflammation.6 Prostanoids are synthesized principally via ... This inference may explain at least in part the differences observed between COX-1 and COX-2 inhibitors. Of note, we found ... Because inflammatory mechanisms influence vitreal neovascularization and cyclooxygenase (COX)-2 promotes tumor angiogenesis, we ...
  http://circ.ahajournals.org/content/108/2/198
*  Anti-COX2 / Cyclooxygenase 2 antibody - C-terminal, prediluted (ab15192)
Cyclooxygenase 2 antibody validated for IHC and tested in Human. Immunogen corresponding to synthetic peptide ... Anti-COX2 / Cyclooxygenase 2 antibody - C-terminal, prediluted. See all COX2 / Cyclooxygenase 2 primary antibodies. ... Glucocorticoid-regulated inflammatory cyclooxygenase antibody. *Glucocorticoid-regulated inflammatory Prostaglandin G/H ... Formalin-fixed, paraffin-embedded human breast carcinoma tissue stained for COX2 / Cyclooxygenase 2 using ab15192 in ...
  http://www.abcam.com/cox2--cyclooxygenase-2-antibody-c-terminal-prediluted-ab15192.html
*  Tumor cyclooxygenase 2-dependent suppression of dendritic cell function. - PubMed - NCBI
To define the pathways limiting DC function in the tumor microenvironment, we assessed the impact of tumor cyclooxygenase (COX ... Tumor cyclooxygenase 2-dependent suppression of dendritic cell function.. Sharma S1, Stolina M, Yang SC, Baratelli F, Lin JF, ... Bone marrow-derived DCs were cultured in either tumor supernatant (TSN) or TSN from COX-2-inhibited tumors. After culture, DCs ... We conclude that inhibition of tumor COX-2 expression or activity can prevent tumor-induced suppression of DC activities. ...
  https://www.ncbi.nlm.nih.gov/pubmed/12631593
*  COX-2 inhibitor - Wikipedia
... cyclooxygenase. Prostaglandins whose synthesis involves the cyclooxygenase-I enzyme, or COX-1, are responsible for maintenance ... 170-fold more potent in inhibiting COX-1 than COX-2. Studies of meloxicam 7.5 mg per day for 23 days find a level of gastric ... "Evaluation of natural products on inhibition of inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) in cultured ... Some COX-2 inhibitors are used in a single dose to treat pain after surgery. Etoricoxib appears as good as if not better than ...
  https://en.wikipedia.org/wiki/COX-2_inhibitor
*  Anti-COX2 / Cyclooxygenase 2 antibody [EPR18376-119] - C-terminal (ab188184)
Cyclooxygenase 2 antibody [EPR18376-119] validated for WB, IP, Flow Cyt, ICC/IF and tested in Mouse. Immunogen… ... COX2 / Cyclooxygenase 2 was immunoprecipitated from 0.35 mg of NIH/3T3 (mouse embryo fibroblast cell line) whole cell lysate ... All lanes : Anti-COX2 / Cyclooxygenase 2 antibody [EPR18376-119] - C-terminal (ab188184) at 1/1000 dilution. Lane 1 : Untreated ... Anti-COX2 / Cyclooxygenase 2 antibody [EPR18376-119] - C-terminal (ab188184) at 1/1000 dilution + NIH/3T3 (mouse embryo ...
  http://www.abcam.com/cox2--cyclooxygenase-2-antibody-epr18376-119-c-terminal-ab188184.html
*  Patent US6696477 - Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and ... - Google Patents
... compositions and methods for treating disorders mediated by cyclooxygenase-2 or 5-lipoxygenase, such as inflammation. Compounds ... a. Preparation of recombinant COX baculoviruses. Recombinant COX-1 and COX-2 were prepared as described by Gierse et al, [J. ... Evaluation of COX-1 and COX-2 activity in vitro. The compounds of this invention exhibited inhibition in vitro of COX-2. The ... b. Assay for COX-1 and COX-2 and COX-2 activity ... to generate the baculovirus transfer vectors for COX-1 and COX- ...
  http://www.google.com/patents/US6696477?dq=6480844
*  Cyclooxygenase-2 Modulates Afferent Arteriolar Responses to Increases in Pressure | Hypertension
Because COX produces both vasoconstrictor and vasodilator metabolites, depending on which types of renal cells generate the COX ... Recent immunohistochemical studies have revealed the unique presence of an inducible isoform of COX, COX-2, in the kidney; its ... Both nitric oxide (NO) and cyclooxygenase (COX) metabolites are recognized as paracrine factors of renal microvascular function ... Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction. J Clin Invest. 1994;94: ...
  http://hyper.ahajournals.org/content/34/4/843
*  No evidence that COX-2 inhibitors provide greater stomach protection
Risk of adverse gastrointestinal outcomes in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti- ... Of 88,867 controls, 33% had been prescribed an NSAID and 6% had been prescribed a COX-2 inhibitor. Increased risks of adverse ... There is no evidence to back up claims that the new generation of anti-inflammatory drugs (COX-2 inhibitors) are less harmful ... These results suggest that COX-2 inhibitors may not be as safe as originally thought, although a possible confounding effect ...
  http://www.innovations-report.com/html/reports/medicine-health/report-52482.html
*  Cyclooxygenase-2 targeted in vivo imaging of cancer | Cancer Epidemiology, Biomarkers & Prevention
Cyclooxygenase-2 targeted in vivo imaging of cancer. jashim uddin, Brenda Crews, Lawrence Marnett, Kotha Subbaramaiah and ... Cyclooxygenase-2 targeted in vivo imaging of cancer. jashim uddin, Brenda Crews, Lawrence Marnett, Kotha Subbaramaiah and ... Cyclooxygenase-2 targeted in vivo imaging of cancer. jashim uddin, Brenda Crews, Lawrence Marnett, Kotha Subbaramaiah and ... Cyclooxygenase-2 targeted in vivo imaging of cancer Message Subject (Your Name) has forwarded a page to you from Cancer ...
  http://cebp.aacrjournals.org/content/16/12_Supplement/A59
*  COX-2 inhibitor facts, information, pictures | Encyclopedia.com articles about COX-2 inhibitor
Make research projects and school reports about COX-2 inhibitor easy with credible articles from our FREE, online encyclopedia ... and pictures about COX-2 inhibitor at Encyclopedia.com. ... "COX-2 inhibitor." A Dictionary of Nursing. . Encyclopedia.com. ... COX-2 inhibitor n. an anti-inflammatory drug (see NSAID) that selectively blocks the action of the enzyme cyclo-oxygenase 2 ( ... COX-2 inhibitor A Dictionary of Nursing © A Dictionary of Nursing 2008, originally published by Oxford University Press 2008. ...
  https://www.encyclopedia.com/medicine/drugs/pharmacology/cox-2-inhibitor
*  The Janus Face of Cyclooxygenase-2 in Ischemic Stroke | Stroke
A third isoform of COX (COX-3) has also been described but is not shown here. Each prostanoid acts on ≥1 specific G-protein- ... COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and ... From Arachidonic Acid to Prostanoids: COX, Isomerases, and Prostanoid Receptors. *COX-2 and the Brain: Roles in Models of ... From Arachidonic Acid to Prostanoids: COX, Isomerases, and Prostanoid Receptors. *COX-2 and the Brain: Roles in Models of ...
  http://stroke.ahajournals.org/content/36/2/182