Regulation of cAMP-Dependent Protein Kinase Subunit Expression in CATH.a and SH-SY5Y Cells | Journal of Pharmacology and...
1990) The expression of cAMP-dependent protein kinase subunits in primary rat hepatocyte cultures: Cyclic AMP down-regulates ... 1981) Turnover of regulatory subunit of cyclic AMP-dependent protein kinase in S49 mouse lymphoma cells: Regulation by ... 1991) Differential regulation of the stability of cyclic AMP-dependent protein kinase messenger RNA in normal versus neoplastic ... cAMP-dependent protein kinase. RI. regulatory type I. RII. regulatory type II. Rp-8Br-cAMPS. 8-bromoadenosine-3′,5′-cyclic ...http://jpet.aspetjournals.org/content/286/2/1058
Assembly and regulation of dynamic PKA macromolecular signaling systems - Susan Taylor
cAMP-dependent protein kinase (PKA), ubiquitous in mammalian cells, regulates a plethora of cell processes including ... Cyclic AMP-dependent protein kinase (PKA), ubiquitous in mammalian cells and associated with many diseases, including cancers, ... cAMP-dependent protein kinase (PKA), ubiquitous in mammalian cells, regulates a plethora of cell processes including ... 2016) Protein Kinase A (PKA) Type I Interacts with P-Rex1, a Rac Guanine Nucleotide Exchange Factor: EFFECT ON PKA LOCALIZATION ...http://grantome.com/grant/NIH/R01-GM034921-29A1
A Single Second Messenger | Circulation Research
A-kinase anchoring proteins (AKAPs) are known to localize cAMP-dependent protein kinase (PKA) to different subcellular ... for synthesis of cyclic AMP (cAMP), guanylyl cyclase for synthesis of cyclic GMP (cGMP), cyclic nucleotide phosphodiesterase ( ... Compartmentation of cyclic nucleotide signaling in the heart: the role of A-kinase anchoring proteins. Circ Res. 2006; 98: 993- ... The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways. Nature. 2005; 437: 574-578. ...http://circres.ahajournals.org/content/99/8/790
cAMP-dependent protein kinase catalytic subunit beta
The encoded protein is a catalytic subunit of cAMP (cyclic AMP)-dependent protein kinase, which mediates signalling though cAMP ... The protein encoded by this gene is a member of the serine/threonine protein kinase family. ... Fluorescence polarization-based biochemical high throughput dose response assay for activators of the Protein Kinase A-R2B (PKA ... Counterscreen for activators of the Protein Kinase A-R2B (PKA-R2B) complex: fluorescence polarization-based biochemical high ...https://pharos.nih.gov/idg/targets/P22694
Endogenous substrate proteins for Ca2+-calmodulin-dependent, Ca2+-phospholipid-dependent and cyclic AMP-dependent protein...
Ca2+-phospholipid-dependent and cyclic AMP-dependent protein kinases in mouse pancreatic islets. P Thams, K Capito, C J ... Endogenous substrate proteins for Ca2+-calmodulin-dependent, Ca2+-phospholipid-dependent and cyclic AMP-dependent protein ... Endogenous substrate proteins for Ca2+-calmodulin-dependent, Ca2+-phospholipid-dependent and cyclic AMP-dependent protein ... Endogenous substrate proteins for Ca2+-calmodulin-dependent, Ca2+-phospholipid-dependent and cyclic AMP-dependent protein ...http://www.biochemj.org/content/221/1/247
"Retinoid acid increases cyclic amp-dependent protein kinase activity i" by R M. Niles and M P. Logue
Retinoid acid increases cyclic amp-dependent protein kinase activity in b16-f1 mouse melanoma cells. Abstr. ... Niles, R M. and Logue, M P., "Retinoid acid increases cyclic amp-dependent protein kinase activity in b16-f1 mouse melanoma ...https://mouseion.jax.org/ssbb1979/1639/
Cyclic AMPdependent protein kinase | definition of Cyclic AMPdependent protein kinase by Medical dictionary
Cyclic AMPdependent protein kinase explanation free. What is Cyclic AMPdependent protein kinase? Meaning of Cyclic AMPdependent ... protein kinase medical term. What does Cyclic AMPdependent protein kinase mean? ... Looking for online definition of Cyclic AMPdependent protein kinase in the Medical Dictionary? ... cAMP-dependent protein kinase. (redirected from Cyclic AMPdependent protein kinase) cAMP-dependent protein kinase. a tetrameric ...http://medical-dictionary.thefreedictionary.com/Cyclic+AMPdependent+protein+kinase
Taurine activates delayed rectifier Kv channels via a metabotropic pathway in retinal neurons.
EC 220.127.116.11/Cyclic AMP-Dependent Protein Kinases; EC 18.104.22.168/Protein Kinase C ... Cyclic AMP-Dependent Protein Kinases / physiology. Delayed Rectifier Potassium Channels / physiology*. HEK293 Cells. Humans. ... Protein Kinase C / physiology. Receptor, Serotonin, 5-HT2A / physiology*. Retinal Neurons / drug effects*, physiology. Taurine ... Moreover, we found that taurine enhanced K(V) channels via intracellular protein kinase C-mediated pathways. When 5-HT(2A) ...http://www.biomedsearch.com/nih/Taurine-Activates-Delayed-Rectifier-KV/23045337.html
Neuronal memory allocation - Wikipedia
Nguyen, P. V., & Woo, N. H. (2003). Regulation of hippocampal synaptic plasticity by cyclic AMP-dependent protein kinases. ... For example, the cyclic adenosine monophosphate (cAMP) and protein kinase A (PKA) pathways appear to participate in neuronal ... cyclic AMP responsive element-binding protein) in this process. Certain synapses on recruited neurons are more likely to ... The dendritic branch is the preferred integrative unit for protein synthesis-dependent LTP. Neuron 69, 132-146 (2011). Harvey, ...https://en.wikipedia.org/wiki/Neuronal_memory_allocation
Isolation and characterization of the highly phosphorylated repeat domain of distinct heavy neurofilament subunit (NF-H)...
Dosemeci, A., and Pont, H. C. (1992). Association of cyclic AMP dependent protein kinase with neurofilaments.Biochem. J. 282: ... Ca2+-calmodulin-dependent protein kinase II phosphorylates various types of non-epithelial intermediate filament proteins. ... Gonda, Y., Nishizawa, Y., Ando, S., Kitamura, S., Minoura, Y., Nshi, Y., and Inagaki, M. (1990). Involvement of protein kinase ... Julien, J.-P., Smoluk, G. D., and Muspynski, W. E. (1983). Characteristics of protein kinase activity associated with rat ...https://link.springer.com/article/10.1007/BF02150227
Frontiers | The Segregated Expression of Voltage-Gated Potassium and Sodium Channels in Neuronal Membranes: Functional...
Kv4.2 phosphorylation by cyclic AMP-dependent protein kinase. J. Biol. Chem. 275, 5337-5346. doi: 10.1074/jbc.275.8.5337 ... Protein kinase a mediates activity-dependent Kv4.2 channel trafficking. J. Neurosci. 28, 7513-7519. doi: 10.1523/JNEUROSCI.1951 ... the Kv4.2 channel also associates with the A-kinase-anchoring protein (AKAP) complex, providing local coupling with kinase and ... 2000). The A-type potassium channel Kv4.2 is a substrate for the mitogen-activated protein kinase ERK. J. Neurochem. 75, 2277- ...https://www.frontiersin.org/articles/10.3389/fncel.2017.00115/full
A Heterotrimeric G Protein of the Gi Family is Required for cAMP-triggered Trafficking of Aquaporin 2 in Kidney Epithelial...
... an event initiated by an increase in cAMP and activation of protein kinase A. The subsequent steps of the signaling cascade are ... To identify proteins involved in the AQP2 shuttle we exploited a recently developed cell line (CD8) derived from the rabbit ... Correspondingly, two alpha subunits of PTX-sensitive G proteins, Galphai2 and Galphai3, were identified by Western blotting. ... protein kinase A DEFINITION: Cyclic AMP-dependent protein kinase. Protein kinase A is a necessary part of the molecular cascade ...http://www.ndif.org/articles/22-A_Heterotrimeric_G_Protein_of_the_Gi_Family_is_Required_for_cAMPtriggered_Trafficking_of_Aquaporin_2_in_Kidney_Epithelial_Cells/body
Similar articles for PubMed (Select 1845792) - PubMed - NCBI
Cyclic AMP-dependent protein kinase in human embryonic palate mesenchymal cells.. Greene RM, Lloyd MR, Pisano MM. ...https://www.ncbi.nlm.nih.gov/pubmed?linkname=pubmed_pubmed&from_uid=1845792
Frontiers | Brief environmental enrichment elicits metaplasticity of hippocampal synaptic potentiation in vivo | Frontiers in...
Nguyen, P. V., and Woo, N. H. (2003). Regulation of hippocampal synaptic plasticity by cyclic AMP-dependent protein kinases. ... Ca2+/calmodulin-dependent kinase II (CaMKII), cyclic adenosine monophosphate response element-binding protein (CREB) (Huang et ... 2005). Hippocampal synaptic metaplasticity requires inhibitory autophosphorylation of Ca2+/calmodulin-dependent kinase II. J. ... Hippocampus-dependent social recognition memory (of rodent identity and conspecifics) is sustained for periods of up to 7 days ...https://www.frontiersin.org/articles/10.3389/fnbeh.2012.00085/full
The marijuana component cannabidiol inhibits β-amyloid-induced tau protein hyperphosphorylation through Wnt/β-catenin pathway...
Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase. Eur J Biochem 107(2):519-527PubMedCrossRefGoogle ... Sperber BR, Leight S, Goedert M, Lee VM (1995) Glycogen synthase kinase-3 beta phosphorylates tau protein at multiple sites in ... Garrido JL, Godoy JA, Alvarez A, Bronfman M, Inestrosa NC (2002) Protein kinase C inhibits amyloid beta peptide neurotoxicity ... Doble BW, Woodgett JR (2003) GSK-3: tricks of the trade for a multi-tasking kinase. J Cell Sci 116:1175-1186PubMedCrossRef ...https://link.springer.com/article/10.1007%2Fs00109-005-0025-1
HDAC8 - Wikipedia
"Negative regulation of histone deacetylase 8 activity by cyclic AMP-dependent protein kinase A". Mol. Cell. Biol. 24 (2): 765- ... The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase ... HDAC8 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text from ... Gantt SL, Gattis SG, Fierke CA (2006). "Catalytic activity and inhibition of human histone deacetylase 8 is dependent on the ...https://en.wikipedia.org/wiki/HDAC8
GP1BB - Wikipedia
"Platelet glycoprotein Ib beta is phosphorylated on serine 166 by cyclic AMP-dependent protein kinase". J. Biol. Chem. 264 (26 ... GP1BB protein, human at the US National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text from ... Du X, Harris SJ, Tetaz TJ, Ginsberg MH, Berndt MC (July 1994). "Association of a phospholipase A2 (14-3-3 protein) with the ... Du X, Harris SJ, Tetaz TJ, Ginsberg MH, Berndt MC (1994). "Association of a phospholipase A2 (14-3-3 protein) with the platelet ...https://en.wikipedia.org/wiki/GP1BB
Oncogenic Functions of Secreted Frizzled-Related Protein 2 in Human Renal Cancer | Molecular Cancer Therapeutics
Phosphorylation of β-catenin by cyclic AMP-dependent protein kinase. J Biol Chem 2006;281:9971-6. ... G protein-coupled receptors, are the major proteins that bind to Wnt proteins on the plasma membrane and trigger Wnt pathway ... A new secreted protein that binds to Wnt proteins and inhibits their activities. Nature 1999;398:431-6. ... Antibodies against cyclin B2, cyclin-dependent kinase 2 (CDK2), and Bcl2 were purchased from Santa Cruz Biotechnology. An ...http://mct.aacrjournals.org/content/9/6/1680
Inhibition of Glycogen Synthase Kinase 3β Attenuates Neurocognitive Dysfunction Resulting from Cranial Irradiation | Cancer...
Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase. Eur J Biochem 1980; 107: 519-27. ... Cyclic AMP promotes neuronal survival by phosphorylation of glycogen synthase kinase 3β. Mol Cell Biol 2000; 20: 9356-63. ... such as cyclic AMP-responsive element binding protein and heat shock factor 1 ( 14), and facilitating proapoptotic ... Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade. Proc Natl ...http://cancerres.aacrjournals.org/content/68/14/5859.long
BRSK2 - Wikipedia
"BRSK2 is activated by cyclic AMP-dependent protein kinase A through phosphorylation at Thr260". Biochemical and Biophysical ... BR serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the BRSK2 gene. GRCh38: Ensembl release 89: ... "LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1". The EMBO Journal. 23 (4): 833- ... "Entrez Gene: BRSK2 BR serine/threonine kinase 2". Human BRSK2 genome location and BRSK2 gene details page in the UCSC Genome ...https://en.wikipedia.org/wiki/BRSK2
SMART: Secondary literature for RIIa domain
Cyclic AMP-dependent protein kinase is tethered to protein kinase A anchoring proteins (AKAPs) through regulatory subunits (R) ... of the cyclic AMP-dependent protein kinase (cAPK), the heat-stable protein kinase inhibitors (PKIs) and the regulatory (R) ... which contains the active site of the inhibitor protein of the cyclic AMP-dependent protein kinase [Cheng, Van Pattern, Smith ... the active inhibitory fragment of the inhibitor protein of the cyclic AMP-dependent protein kinase. ...http://smart.embl-heidelberg.de/smart/show_secondary.cgi?domain=RIIa
Control of GluR1 AMPA Receptor Function by cAMP-Dependent Protein Kinase | Journal of Neuroscience
Inhibition of cyclic AMP-dependent kinase by expression of a protein kinase inhibitor/enhanced green fluorescent fusion protein ... 1996) Transient activation of cyclic AMP-dependent protein kinase during hippocampal long-term potentiation. J Biol Chem 271: ... 1995) Association of protein kinase A and protein phosphatase 2B with a common anchoring protein. Science 267:108-111. ... Control of GluR1 AMPA Receptor Function by cAMP-Dependent Protein Kinase. T. G. Banke, D. Bowie, H.-K. Lee, R. L. Huganir, A. ...http://www.jneurosci.org/content/20/1/89?ijkey=6516d0f6e54ae4839e5d63ec1a2689b2c1d8909e&keytype2=tf_ipsecsha
Warburg Revisited: Regulation of Mitochondrial Metabolism by Voltage-Dependent Anion Channels in Cancer Cells | Journal of...
1995) Mitochondrial VDAC can be phosphorylated by cyclic AMP-dependent protein kinase. Biochem Biophys Res Commun 209:213-217. ... voltage-dependent anion channel. PKA. protein kinase A. GSK3β. glycogen synthase kinase-3β. TMRM. tetramethylrhodamine ... Tubulin-dependent suppression of ΔΨm is further potentiated by protein kinase A activation and glycogen synthase kinase-3β ... namely formation of proteins, nucleic acids, and membranes. Tubulin and protein kinases, especially PKA activation, act to ...http://jpet.aspetjournals.org/content/342/3/637.full
The role of diacylglycerol as a modulator of oxytocin-stimulated phasic contractions in myometrium from pregnant and...
... protein kinase C activation leads to inhibition of phasic contractions. These studies are designed to determine wh ... The role of diacylglycerol in the phosphatidylinositol-signaling pathway is to activate protein kinase C. In the myometrium, ... 6265788 - Inhibition of smooth muscle tension by cyclic amp-dependent protein kinase.. 9263758 - Modulation of the calcium ... OBJECTIVE: The role of diacylglycerol in the phosphatidylinositol-signaling pathway is to activate protein kinase C. In the ...http://www.biomedsearch.com/nih/role-diacylglycerol-as-modulator-oxytocin/10764478.html
Synaptotagmin-12 Phosphorylation by cAMP-Dependent Protein Kinase is Essential for Hippocampal Mossy Fiber LTP
Regulation of hippocampal synaptic plasticity by cyclic AMP-dependent protein kinases. Prog Neurobiol. 2003;71:401-437. [PubMed ... Syt12 is phosphorylated by cAMP-dependent protein kinase-A at serine-97 in an activity-dependent manner, suggesting a function ... Syt12 is phosphorylated by cAMP-dependent protein kinase A (PKA) at a single residue (serine-97), suggesting that Syt12 may ... Synaptotagmin-12 Phosphorylation by cAMP-Dependent Protein Kinase is Essential for Hippocampal Mossy Fiber LTP. Yea Jin Kaeser- ...http://pubmedcentralcanada.ca/pmcc/articles/PMC3703303/?lang=en-ca