KEGG BRITE: KEGG Orthology (KO) - Tupaia chinensis (Chinese tree shrew)
... protein kinase D [EC:18.104.22.168] K05870 CREB1; cyclic AMP-responsive element-binding protein 1 K04450 ATF2; cyclic AMP-dependent ... protein kinase C epsilon 102494291 PRKD2; protein kinase D2 102492283 PRKD1; protein kinase D1 102472549 PRKD3; protein kinase ... 102495954 PRKCA; protein kinase C alpha 102469271 PRKCB; protein kinase C beta 102497204 PRKCG; protein kinase C gamma ... 102473558 CAMK1; calcium/calmodulin dependent protein kinase I 102478578 CAMK1D; calcium/calmodulin dependent protein kinase ID ...http://www.genome.jp/kegg-bin/get_htext?tup00001+102491327
In vitro phosphorylation of human complement factor C3 by protein kinase A and protein kinase C : Effects on the classical and...
... was phosphorylated in vitro by cyclic AMP-dependent protein kinase (protein kinase A) and Ca2+-activated, phospholipid- ... dependent protein kinase (protein kinase C). Both protein kinases phosphorylated the same serine residue(s) located in the C3a ... was 20 times higher for protein kinase C than for protein kinase A although a 10 times lower ratio of protein kinase to C3 was ... Protein kinase A gave a maximal incorporation of 1 mol of phosphate/mol of C3 while that value with protein kinase C was 1.5 ...http://uu.diva-portal.org/smash/record.jsf?pid=diva2:515546
Endogenous substrate proteins for Ca2+-calmodulin-dependent, Ca2+-phospholipid-dependent and cyclic AMP-dependent protein...
Ca2+-phospholipid-dependent and cyclic AMP-dependent protein kinases in mouse pancreatic islets. P Thams, K Capito, C J ... Endogenous substrate proteins for Ca2+-calmodulin-dependent, Ca2+-phospholipid-dependent and cyclic AMP-dependent protein ... Endogenous substrate proteins for Ca2+-calmodulin-dependent, Ca2+-phospholipid-dependent and cyclic AMP-dependent protein ... Endogenous substrate proteins for Ca2+-calmodulin-dependent, Ca2+-phospholipid-dependent and cyclic AMP-dependent protein ...http://www.biochemj.org/content/221/1/247
Effect of indomethacin on the cyclic AMP-dependent protein kinase. | Docphin
Effect of indomethacin on the cyclic AMP-dependent protein kinase. , European journal of pharmacology , 5/2/1980 ... Effect of indomethacin on the cyclic AMP-dependent protein kinase. R E Catalán M D Aragones A M Martinez M Armijo M Piña 5/2/ ... Catalán RE, Aragones MD, Martinez AM, Armijo M, Piña M. Effect of indomethacin on the cyclic AMP-dependent protein kinase. Eur ... Indomethacin inhibited cyclic AMP-dependent protein kinase activity in small intestine in in vivo experiments. An inverse ...https://www.docphin.com/research/article-detail/15728797/PubMedID-6247165/Effect-of-indomethacin-on-the-cyclic-AMP-dependent-protein-kinase
Reversible phosphorylation of Drp1 by cyclic AMP‐dependent protein kinase and calcineurin regulates mitochondrial fission and...
... dependent kinase and phosphatase, cyclic AMP‐dependent protein kinase (PKA) and calcineurin (also called protein phosphatase 2B ... Ser 656 is phosphorylated by cyclic AMP‐dependent protein kinase and dephosphorylated by calcineurin, and its phosphorylation ... Reversible phosphorylation of Drp1 by cyclic AMP‐dependent protein kinase and calcineurin regulates mitochondrial fission and ... Drp1, dynamin‐related protein 1; GFP, green fluorescent protein; PKA, cAMP‐dependent protein kinase, pS40 TH, phospho‐Ser 40 ...http://embor.embopress.org/content/8/10/939?ijkey=5fc22c8fac9c53f38184d2f4c5d3fe3cdc0ede60&keytype2=tf_ipsecsha
"Retinoid acid increases cyclic amp-dependent protein kinase activity i" by R M. Niles and M P. Logue
Retinoid acid increases cyclic amp-dependent protein kinase activity in b16-f1 mouse melanoma cells. Abstr. ... Niles, R M. and Logue, M P., "Retinoid acid increases cyclic amp-dependent protein kinase activity in b16-f1 mouse melanoma ...https://mouseion.jax.org/ssbb1979/1639/
The structure and expression of cyclic AMP-dependent protein kinase subunit genes in Caenorhabditis elegans and mouse Friend...
The structure and expression of cyclic AMP-dependent protein kinase subunit genes in Caenorhabditis elegans and mouse Friend ... cAMP-dependent protein kinase (PKA) regulates numerous cellular processes in eukaryotes in response to extracellular and ... Phosphorylation of substrate proteins leads to control of enzyme activity and/or gene expression. PKA is a heterotetramer ... Evidence is presented for the presence of this protein in the nematode. The C transcript is trans-spliced to the ubiquitous 22 ...http://repository.yu.edu/handle/20.500.12202/3321
Cyclic AMPdependent protein kinase | definition of Cyclic AMPdependent protein kinase by Medical dictionary
Cyclic AMPdependent protein kinase explanation free. What is Cyclic AMPdependent protein kinase? Meaning of Cyclic AMPdependent ... protein kinase medical term. What does Cyclic AMPdependent protein kinase mean? ... Looking for online definition of Cyclic AMPdependent protein kinase in the Medical Dictionary? ... cAMP-dependent protein kinase. (redirected from Cyclic AMPdependent protein kinase) cAMP-dependent protein kinase. a tetrameric ...http://medical-dictionary.thefreedictionary.com/Cyclic+AMPdependent+protein+kinase
Taurine activates delayed rectifier Kv channels via a metabotropic pathway in retinal neurons.
EC 22.214.171.124/Cyclic AMP-Dependent Protein Kinases; EC 126.96.36.199/Protein Kinase C ... Cyclic AMP-Dependent Protein Kinases / physiology. Delayed Rectifier Potassium Channels / physiology*. HEK293 Cells. Humans. ... Protein Kinase C / physiology. Receptor, Serotonin, 5-HT2A / physiology*. Retinal Neurons / drug effects*, physiology. Taurine ... Moreover, we found that taurine enhanced K(V) channels via intracellular protein kinase C-mediated pathways. When 5-HT(2A) ...http://www.biomedsearch.com/nih/Taurine-Activates-Delayed-Rectifier-KV/23045337.html
Isolation and characterization of the highly phosphorylated repeat domain of distinct heavy neurofilament subunit (NF-H)...
Dosemeci, A., and Pont, H. C. (1992). Association of cyclic AMP dependent protein kinase with neurofilaments.Biochem. J. 282: ... Ca2+-calmodulin-dependent protein kinase II phosphorylates various types of non-epithelial intermediate filament proteins. ... Gonda, Y., Nishizawa, Y., Ando, S., Kitamura, S., Minoura, Y., Nshi, Y., and Inagaki, M. (1990). Involvement of protein kinase ... Julien, J.-P., Smoluk, G. D., and Muspynski, W. E. (1983). Characteristics of protein kinase activity associated with rat ...https://link.springer.com/article/10.1007/BF02150227
Frontiers | The Segregated Expression of Voltage-Gated Potassium and Sodium Channels in Neuronal Membranes: Functional...
Kv4.2 phosphorylation by cyclic AMP-dependent protein kinase. J. Biol. Chem. 275, 5337-5346. doi: 10.1074/jbc.275.8.5337 ... Protein kinase a mediates activity-dependent Kv4.2 channel trafficking. J. Neurosci. 28, 7513-7519. doi: 10.1523/JNEUROSCI.1951 ... the Kv4.2 channel also associates with the A-kinase-anchoring protein (AKAP) complex, providing local coupling with kinase and ... 2000). The A-type potassium channel Kv4.2 is a substrate for the mitogen-activated protein kinase ERK. J. Neurochem. 75, 2277- ...https://www.frontiersin.org/articles/10.3389/fncel.2017.00115/full
Mediates a cAMP-to-PKC Signaling in Inflammatory Pain : An Isolectin B 4 ( ) Neuron-Specific Mechanism - Semantic Scholar
... give proof of principle that the mitogen-activated protein kinase pathway-activating protein Epac also stimulates PKC, describe ... and find proof of principle that G-protein-coupled receptors can activate PKC not only through the G-proteins q and but also ... The isoform of protein kinase C (PKC ) has emerged as a critical second messenger in sensitization toward mechanical ... Selective inhibition of cyclic AMP-dependent protein kinase by isoquinoline derivatives.. *Z X Lu, N H Quazi, L W Deady, G M ...https://www.semanticscholar.org/paper/Mediates-a-cAMP-to-PKC-Signaling-in-Inflammatory-%3A-Hucho-Dina/bbead70e25e00c42a2c4413fb672805333182774
A Heterotrimeric G Protein of the Gi Family is Required for cAMP-triggered Trafficking of Aquaporin 2 in Kidney Epithelial...
... an event initiated by an increase in cAMP and activation of protein kinase A. The subsequent steps of the signaling cascade are ... To identify proteins involved in the AQP2 shuttle we exploited a recently developed cell line (CD8) derived from the rabbit ... Correspondingly, two alpha subunits of PTX-sensitive G proteins, Galphai2 and Galphai3, were identified by Western blotting. ... protein kinase A DEFINITION: Cyclic AMP-dependent protein kinase. Protein kinase A is a necessary part of the molecular cascade ...http://www.ndif.org/articles/22-A_Heterotrimeric_G_Protein_of_the_Gi_Family_is_Required_for_cAMPtriggered_Trafficking_of_Aquaporin_2_in_Kidney_Epithelial_Cells/body
Similar articles for PubMed (Select 1845792) - PubMed - NCBI
Cyclic AMP-dependent protein kinase in human embryonic palate mesenchymal cells.. Greene RM, Lloyd MR, Pisano MM. ...https://www.ncbi.nlm.nih.gov/pubmed?linkname=pubmed_pubmed&from_uid=1845792
Frontiers | Brief environmental enrichment elicits metaplasticity of hippocampal synaptic potentiation in vivo | Frontiers in...
Nguyen, P. V., and Woo, N. H. (2003). Regulation of hippocampal synaptic plasticity by cyclic AMP-dependent protein kinases. ... Ca2+/calmodulin-dependent kinase II (CaMKII), cyclic adenosine monophosphate response element-binding protein (CREB) (Huang et ... 2005). Hippocampal synaptic metaplasticity requires inhibitory autophosphorylation of Ca2+/calmodulin-dependent kinase II. J. ... Hippocampus-dependent social recognition memory (of rodent identity and conspecifics) is sustained for periods of up to 7 days ...https://www.frontiersin.org/articles/10.3389/fnbeh.2012.00085/full
Potentiation of IP3-evoked Ca2+ release by cAMP in perm | Open-i
Cyclic AMP-Dependent Protein Kinases/metabolism. *GTP-Binding Protein alpha Subunits, Gs/metabolism ... C) Concentration-dependent stimulation of Ca2+ release by IP3 alone and with 3 mM 8-Br-cAMP. (D) Concentration-dependent effect ... C) Concentration-dependent stimulation of Ca2+ release by IP3 alone and with 3 mM 8-Br-cAMP. (D) Concentration-dependent effect ... B) Concentration-dependent effect of cAMP on the EC50 for IP3-evoked Ca2+ release from permeabilized HEK-PR1 cells. ( ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC2568025_jcb1830297f04&req=4
The marijuana component cannabidiol inhibits β-amyloid-induced tau protein hyperphosphorylation through Wnt/β-catenin pathway...
Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase. Eur J Biochem 107(2):519-527PubMedCrossRefGoogle ... Sperber BR, Leight S, Goedert M, Lee VM (1995) Glycogen synthase kinase-3 beta phosphorylates tau protein at multiple sites in ... Garrido JL, Godoy JA, Alvarez A, Bronfman M, Inestrosa NC (2002) Protein kinase C inhibits amyloid beta peptide neurotoxicity ... Doble BW, Woodgett JR (2003) GSK-3: tricks of the trade for a multi-tasking kinase. J Cell Sci 116:1175-1186PubMedCrossRef ...https://link.springer.com/article/10.1007%2Fs00109-005-0025-1
Frontiers | VDAC1 as Pharmacological Target in Cancer and Neurodegeneration: Focus on Its Role in Apoptosis | Chemistry
Unfortunately, the lack of an evident druggability of this protein, since it has no defined binding or active sites, makes the ... Unfortunately, the lack of an evident druggability of this protein, since it has no defined binding or active sites, makes the ... Bera, A. K., Ghosh, S., and Das, S. (1995). Mitochondrial VDAC can be phosphorylated by cyclic AMP-dependent protein kinase. ... 2003). Identification of the protein-protein contact site and interaction mode of human VDAC1 with Bcl-2 family proteins. ...https://www.frontiersin.org/articles/10.3389/fchem.2018.00108/full
Oncogenic Functions of Secreted Frizzled-Related Protein 2 in Human Renal Cancer | Molecular Cancer Therapeutics
Phosphorylation of β-catenin by cyclic AMP-dependent protein kinase. J Biol Chem 2006;281:9971-6. ... G protein-coupled receptors, are the major proteins that bind to Wnt proteins on the plasma membrane and trigger Wnt pathway ... A new secreted protein that binds to Wnt proteins and inhibits their activities. Nature 1999;398:431-6. ... Antibodies against cyclin B2, cyclin-dependent kinase 2 (CDK2), and Bcl2 were purchased from Santa Cruz Biotechnology. An ...http://mct.aacrjournals.org/content/9/6/1680
Inhibition of Glycogen Synthase Kinase 3β Attenuates Neurocognitive Dysfunction Resulting from Cranial Irradiation | Cancer...
Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase. Eur J Biochem 1980; 107: 519-27. ... Cyclic AMP promotes neuronal survival by phosphorylation of glycogen synthase kinase 3β. Mol Cell Biol 2000; 20: 9356-63. ... such as cyclic AMP-responsive element binding protein and heat shock factor 1 ( 14), and facilitating proapoptotic ... Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade. Proc Natl ...http://cancerres.aacrjournals.org/content/68/14/5859.long
miR-shRNA expression options. A) Flow chart for express | Open-i
Cyclic AMP/metabolism/pharmacology. *Cyclic AMP-Dependent Protein Kinases/metabolism. *Genetic Vectors ... Retroviral delivery of transcripts targeting isoforms of cAMP-dependent protein kinase in the RAW264.7 murine macrophage cell ... Retroviral delivery of transcripts targeting isoforms of cAMP-dependent protein kinase in the RAW264.7 murine macrophage cell ... range of plasmid or viral vectors.Retroviral delivery of transcripts targeting isoforms of cAMP-dependent protein kinase in the ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC2194719_1471-2199-8-98-5&req=4
SMART: Secondary literature for RIIa domain
Cyclic AMP-dependent protein kinase is tethered to protein kinase A anchoring proteins (AKAPs) through regulatory subunits (R) ... of the cyclic AMP-dependent protein kinase (cAPK), the heat-stable protein kinase inhibitors (PKIs) and the regulatory (R) ... which contains the active site of the inhibitor protein of the cyclic AMP-dependent protein kinase [Cheng, Van Pattern, Smith ... the active inhibitory fragment of the inhibitor protein of the cyclic AMP-dependent protein kinase. ...http://smart.embl-heidelberg.de/smart/show_secondary.cgi?domain=RIIa
Control of GluR1 AMPA Receptor Function by cAMP-Dependent Protein Kinase | Journal of Neuroscience
Inhibition of cyclic AMP-dependent kinase by expression of a protein kinase inhibitor/enhanced green fluorescent fusion protein ... 1996) Transient activation of cyclic AMP-dependent protein kinase during hippocampal long-term potentiation. J Biol Chem 271: ... 1995) Association of protein kinase A and protein phosphatase 2B with a common anchoring protein. Science 267:108-111. ... Control of GluR1 AMPA Receptor Function by cAMP-Dependent Protein Kinase. T. G. Banke, D. Bowie, H.-K. Lee, R. L. Huganir, A. ...http://www.jneurosci.org/content/20/1/89?ijkey=6516d0f6e54ae4839e5d63ec1a2689b2c1d8909e&keytype2=tf_ipsecsha
Tyrosine hydroxylase - Wikipedia
"Direct phosphorylation of brain tyrosine hydroxylase by cyclic AMP-dependent protein kinase: mechanism of enzyme activation". ... that are phosphorylated by a variety of protein kinases. Ser40 is phosphorylated by the cAMP-dependent protein kinase.[ ... is phosphorylated by the calcium-calmodulin-dependent protein kinase. MAPKAPK2 (mitogen-activated-protein kinase-activating ... Roskoski R, Roskoski LM (Jan 1987). "Activation of tyrosine hydroxylase in PC12 cells by the cyclic GMP and cyclic AMP second ...https://en.wikipedia.org/wiki/Tyrosine_3-monooxygenase
The Drosophila radish gene encodes a protein required for anesthesia-resistant memory | PNAS
It encodes a protein with 23 predicted cyclic-AMP-dependent protein kinase (PKA) phosphorylation sequences. The Radish protein ... PKA-dependent phosphorylation of the Radish protein, as suggested by numerous PKA target sites, would logically link ARM to the ... The specific defect of the radish mutant, diminished ARM, normal long-lasting protein-synthesis-dependent memory, provides a ... The Radish protein is similar to a predicted protein from the mosquito Anopheles gambiae (66% identity) and to one from the ...http://www.pnas.org/content/103/46/17496?ijkey=75d6801b0899a96aceba2f6e059b5df55abf597e&keytype2=tf_ipsecsha