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*  Abstract 10893: Cardiac Troponin T Release is Correlated with Diastolic Load in Patients with Nonischemic Heart Failure |...
... cTnT and BNP extracted from heart were describe as the differences between Cs and Ao of cTnT levels (Δ cTnT) and BNP levels (Δ ... Background: Cardiac troponin T (cTnT) is established as a specific biomarker of ongoing myocardial damage and predicts adverse ... Results: cTnT was detectable (cTnT,0.003 ng/mL) in 47 HF patients (92%) and 11 non-HF patients (58%) by highly sensitive assay ... However, it is not fully understood the mechanism underlying cTnT release in nonischemic HF patients because cTnT was ...
  http://circ.ahajournals.org/content/124/Suppl_21/A10893
*  Patent US7732199 - Process for making transplantable cardiomyocytes from human embryonic stem cells - Google Patents
express one or more of the following markers from an endogenous gene: cardiac troponin I (cTnI), cardiac troponin T (cTnT), ... e) isolating the cell fractions containing cells that express cardiac troponin I (cTnI), cardiac troponin T (cTnT), or atrial ... cardiac troponin I (cTnI), and cardiac troponin T (cTnT). Single cells and clusters stained positive for all these markers. The ... cardiac troponin I (cTnI), cardiac troponin T (cTnT), sarcomeric myosin heavy chain (MHC), GATA-4, Nkx2.5, N-cadherin, β1- ...
  http://www.google.com/patents/US7732199?dq=5958006
*  Cardiac structural and functional abnormalities in end stage renal disease patients with elevated cardiac troponin T | Heart
The proportions of patients with diabetes and on dialysis were higher in both groups with raised cTnT. With a cut off cTnT ... Mortality was higher in all patients with raised cTnT.. Conclusions: Patients with ESRD with raised cTnT concentrations have ... with a raised cardiac troponin T (cTnT) concentration. ... The total ischaemic burden during DSE was similar in cTnT ... LV end systolic diameter index and E:Ea ratio were independent predictors of cTnT rises ⩾ 0.04 μg/l and ⩾ 0.10 μg/l, ...
  http://heart.bmj.com/content/92/6/804
*  Cardiac side population cells have a potential to migrate and differentiate into cardiomyocytes in vitro and in vivo | JCB
5 D, b, c, e, and f), cardiac troponin T (cTnT; Fig. 5 D, c and f), MLC2v (Fig. 5 D, a), and SA (Fig. 5 D, b, d, and e). ... cTnT, cardiac troponin T; HDAC, histone deacetylases; MDR, multidrug resistance; MEF, myocyte-enhancer factor; MLC, myosin ... 7 B). Some GFP+ CSPs in the border and injured area expressed cTnT (Fig. 8 A, a-d), vimentin (Fig. 8 A, e-h), von Willebrand ... 8 A, m-p). The percentage of cTnT-positive GFP+ cells in the total GFP+ cells was 4.4%, vimentin-positive GFP+ cells 33%, vWF- ...
  http://jcb.rupress.org/content/176/3/329
*  Study familial hypertrophic cardiomyopathy using patient-specific induced pluripotent stem cells. - PubMed - NCBI
Cardiac Troponin T (CTNT) is a marker for CMs. (B) CMs derived from control S3-iPS4 and two clones of HCM iPSCs were used for ... D) Representative immunostaining of CTNT and α-Actinin to show the sarcomere disorganization in HCM iPSC-CMs. Scale bars, 10 µm ...
  https://www.ncbi.nlm.nih.gov/pubmed/25209314
*  Nanoparticles for diagnosis and therapy of atherosclerosis and myocardial infarction: evolution toward prospective theranostic...
... cardiac troponin I; cTnT: cardiac troponin T; CVD: cardiovascular diseases; Cy5.5: cyanine5.5; Cy7: cyanine7; DAPI: 4′,6- ... Fabrication of anti-human cardiac troponin I immunogold nanorods for sensing acute myocardial damage. Nanoscale Res Lett. 2009; ... cardiac troponin T (cTnT), and connexin43 was detected [69]. ... During the myocardial damage process, the cardiac troponin I ( ... Tang M, Zhou Z, Shangguan L, Zhao F, Liu S. Electrochemiluminescent detection of cardiac troponin I by using soybean peroxidase ...
  http://www.thno.org/v08p4710.htm
*  CYCLosporinE A in Reperfused Acute Myocardial Infarction - Full Text View - ClinicalTrials.gov
... hs-cTnt). [ Time Frame: at day 4 after percutaneous coronary intervention (PCI) ]. High sensitive cardiac troponin T (hs-cTnt) ... Infarct size: Troponin curve (T or I, assayed locally); The time course of troponin release during the first 72 hours after the ... Infarct size: Troponin curve (T or I, assayed locally) [ Time Frame: Time course of troponin release during the first 72 hours ...
  https://clinicaltrials.gov/ct2/show/NCT01650662
*  Path - Heart Flashcards by Laura Vo | Brainscape
cardiac-specific troponins T & I (cTnT & cTnl) & CK-MB 35 What is Rheumatic fever (RF) & what is its progression? ...
  https://www.brainscape.com/flashcards/path-heart-2589418/packs/4520764
*  Acute Management of Pulmonary Embolism - American College of Cardiology
Elevated troponin (cTnI and cTnT). Elevated natriuretic peptides (BNP and N-terminal pro-BNP) ... Troponin I and right ventricular dysfunction for risk assessment in patients with nonmassive pulmonary embolism in the ... Dotted line= patients without right ventricular dysfunction and normal troponin levels. HR = hazard ratio.. Patient Selection ... Solid line= patients with right ventricular dysfunction by echocardiography and elevated troponin levels. Dashed line= patients ...
  http://www.acc.org/latest-in-cardiology/articles/2017/10/23/12/12/acute-management-of-pulmonary-embolism
*  Glucose inhibits cardiac muscle maturation through nucleotide biosynthesis. - PubMed - NCBI
C) Images of phase-contrast and Tnnt2 (cTnT: cardiac Troponin T) immunofluorescent staining of hESC-CMs at day 28. Scale bar = ...
  https://www.ncbi.nlm.nih.gov/pubmed/29231167
*  Frontiers | Updates in Anthracycline-Mediated Cardiotoxicity | Pharmacology
Troponins (Tns) are composed of three subunits: troponin C (cTnC), troponin T (cTnT), and troponin I (cTnI). Troponins make a ... A relationship between troponin levels and the degree of late cardiac dysfunction has also been observed in animal treated with ... Persistent increase in cTnT is also positively correlated with anthracycline dose in children treated with anthracycline for ... In myocardial cells, majority of troponins are located in the sarcomeres and to a lesser extent in the cytoplasm. ...
  https://www.frontiersin.org/articles/10.3389/fphar.2018.01262/full
*  Global Cardiac Biomarker Market Professional Survey Report 2017, Trends, Share, Size Research Report
Figure Troponin (cTnI and cTnT) Picture. Table Major Manufacturers of Troponin (cTnI and cTnT). Figure BNP & NT-proBNP Picture ... 1.2.2 Troponin (cTnI and cTnT). 1.2.3 BNP & NT-proBNP. 1.2.4 Myogloblin. 1.2.5 Others. 1.3 Applications of Cardiac Biomarker. ... Troponin (cTnI and cTnT). BNP & NT-proBNP. Myogloblin. Others. By Application, the market can be split into. Myocardial ... 6.3.2 Troponin (cTnI and cTnT) of Cardiac Biomarker Growth Driving Factor Analysis. 6.3.3 BNP & NT-proBNP of Cardiac Biomarker ...
  https://www.researchmoz.us/global-cardiac-biomarker-market-professional-survey-report-2017-report.html
*  733 Validation of NYHA class II subgrouping in patients with heart failure: correlation with ejection fraction and left...
An abstract of the study "Prognostic Usefulness of Cardiac Troponin-T (cTnT) in Heart Failure Patients," by J. Li and ... 631 Prognostic usefulness of cardiac troponin-T (cTnT) in heart failure patients. // European Journal of Heart Failure. ...
  http://connection.ebscohost.com/c/abstracts/13022640/733-validation-nyha-class-ii-subgrouping-patients-heart-failure-correlation-ejection-fraction-left-ventricular-dysfunction-questionnaire
*  Activin-A and Bmp4 levels modulate cell type specification during CHIR-induced cardiomyogenesis. - PubMed - NCBI
B, typical flow cytometry results showing percentages of cardiac troponin-T (cTnT)-positive cells at Day 14. C, αMHC (MF20) ... A, lower: cTnt flow cytometry of cells in parallel. B, percentages of cTnT+ cells assessed by flow cytometry at Day 14. Bars ... determined by flow cytometry using anti-cTnT. Cultures treated with 10 ng/ml Activin-A began to rhythmically contract at Day 6 ...
  https://www.ncbi.nlm.nih.gov/pubmed/25706534
*  JCI - Single cell transcriptional profiling reveals heterogeneity of human induced pluripotent stem cells
C) Immunostaining for cardiac troponin T (cTnT) of hESC- and hiPSC-derived cardiomyocytes (original magnification, ×20). (D) ...
  https://www.jci.org/articles/view/44635
*  Protocols and Video Articles Authored by Heinrich J. Audebert
May, 2012 , Pubmed ID: 22326514 Myocardial injury indicated by elevation of cardiac troponins (cTnT) can be observed in acute ... 2011 , Pubmed ID: 21824425 Levels of the cardiac muscle regulatory protein troponin T (cTnT) are frequently elevated in ... The pathomechanism of troponin release may relate to co-morbid coronary artery disease and myocardial ischemia or, ... Troponin Elevation in Acute Ischemic Stroke (TRELAS)--protocol of a Prospective Observational Trial BMC Neurology. ...
  https://www.jove.com/author/Heinrich+J._Audebert
*  Patent US8119393 - Membrane array and analytical device - Google Patents
... troponin T (cTnT), troponin I (cTnI), creatinine kinase MB (CK-MB), human chorionic gonadotropin (hCG), luteinizing hormone (LH ... troponin T (cTnT), troponin I (cTnI), creatinine kinase MB (CK-MB), human chorionic gonadotropin (hCG), luteinizing hormone (LH ... troponins T (cTnT) and I (cTnI) and creatinine kinase MB (CK-MB). Furthermore, hormones associated with pregnancy or ovulation ... A human cardiac troponin I test (TnI) device using one drop of whole blood sample is prepared according to current invention. ...
  http://www.google.com/patents/US8119393?dq=6,123,819
*  sfrp1 promotes cardiomyocyte differentiation in Xenopus via negative-feedback regulation of Wnt signalling | Development
Cardiac Troponin T (cTnT/tnnt2) immunohistochemistry analysis was as described (Lavery et al., 2008b). Sections were imaged the ... O-R) Terminal differentiation of the heart was analysed in stage 41 embryos by immunofluorescence for cardiac Troponin T (cTnT ... For each experimental sample the fluorescence intensity of cTnT (red) was measured, giving a percentage area of cTnT expression ... sfrp1MO1 injection causes reduced cTnT expression (L), but embryos co-injected with sfrp1MO1 and wnt6MO3 show enlarged cTnT ...
  http://dev.biologists.org/content/140/7/1537
*  Melphalan and Dexamethasone With or Without Bortezomib in Treating Patients With Previously Untreated Systemic Light-Chain...
If troponin T (cTnT) is not available at local institution then troponin I (cTnI) may be used. Thresholds for cTnT, cTnI, and ... Stage I patients have both troponin-T (or I) and NT-proBNP below the threshold. Stage II patients have either troponin-T (I) or ... Stage III patients have troponin-T (or I) and simultaneous NT-proBNP above the threshold. Stage III patients are further ... The amyloid cardiac staging system is based on NT-proBNP and troponin-T levels. ...
  https://clinicaltrials.gov/ct2/show/study/NCT01078454?show_locs=Y
*  High-Sensitivity Troponins and Outcomes After Myocardial Infarction | JACC: Journal of the American College of Cardiology
cTn = conventional cardiac troponin; hs-cTnT = high-sensitivity cardiac troponin T; MI = myocardial infarction; RR = relative ... Troponin assays. From 2009 to 2012, the current iteration of the hs-cTnT assay (Roche Diagnostics, Basel, Switzerland) was the ... cardiac troponin. HR. hazard ratio. hs-cTn. high-sensitivity cardiac troponin. MI. myocardial infarction. ... Background It remains unknown how the introduction of high-sensitivity cardiac troponin T (hs-cTnT) has affected the incidence ...
  http://www.onlinejacc.org/content/71/23/2616
*  Dedifferentiation and Proliferation of Mammalian Cardiomyocytes
... still expressing weakly the myofilament protein troponin T (cTnT), budding off a smaller round cell that does not express cTnT ... Some dedifferentiated myocytes no longer expressed myofilament cardiac troponin T (cTnT) (Figure 3A). ... Cardiomyocyte preparations are positive to cTnT (green, A) or α-MHC (green, B-D), but not to stem cell marker c-kit (red, A), ... Expression of cardiac markers was assessed using antibodies including mouse mAb for α-MHC from Abcam or Sigma, mouse mAb cTnT, ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2933247/
*  Reproductive hormone levels and differential mitochondria-related oxidative gene expression as potential mechanisms for gender...
Heart weight, cardiac lesion score and serum levels of cardiac troponin T (cTnT) were used to determine cardiotoxicity. Serum ... Lesion score and cTnT inversely correlated with hormone levels. Reduced levels of both sex hormones were observed after Dox ...
  https://www.sigmaaldrich.com/catalog/papers/26108538