WHO | Severe Acute Respiratory Syndrome (SARS) - multi-country outbreak - Update
Disease Outbreak Reported. As of 15 March 2003, reports of over 150 cases of Severe Acute Respiratory Syndrome (SARS), an atypical pneumonia of unknown aetiology, have been received by the World Health Organization (WHO) since 26 February 2003 ( see previous report ). WHO is co-ordinating the international investigation of this outbreak and is working closely with health authorities in the affected countries to provide epidemiological, clinical and logistical support as required.. SARS was first recognised on the 26 February 2003 in Hanoi, Viet Nam. The causative agent has yet to be identified. The main symptoms and signs include high fever (>38 degrees C), cough, shortness of breath or breathing difficulties (see Case definitions for Surveillance of Severe Acute Respiratory Syndrome). A proportion of patients with SARS develop severe pneumonia; some of whom ...http://who.int/csr/don/2003_03_16/en/
Lirias: Biosafety risk assessment of the severe acute respiratory syndrome (SARS) Coronavirus and containment measures for the...
At the end of 2002, an outbreak of a new viral respiratory illness, called SARS (Severe Acute Respiratory Syndrome virus), occurred in China. The disease spread over Asia, North America, Europe and Africa. In response to the SARS outbreak, the World Health Organization (WHO) coordinated an international collaboratorion that included clinical, epidemiologic, and laboratory investigations, and initiated efforts to control the spread of SARS. As in other countries, Belgium has been decided to establish biosafety guidelines and recommendations with particular emphasis on handling clinical specimens associated with SARS for research, production, and clinical laboratories. Taking into account that there is so far no SARS case reported in Belgium as well as in other countries in the world, and based on a scientific risk assessment related to the contained use of biological agents, the SARS-CoV was classified as a Risk Group 3 ...https://lirias.kuleuven.be/handle/123456789/161707
Dynamic Profiles of Cytokine/Chemokine in Severe Acute Respiratory Syndrome - Tabular View - ClinicalTrials.gov
Severe acute respiratory syndrome (SARS) is an emerging infectious disease caused by a novel coronavirus (SARS-CoV). The major clinical features of SARS include fever, dyspnea, lymphopenia, and a rapid progression of pulmonary infiltrates on chest radiologic images. The SARS-related deaths have resulted mainly from pulmonary complications, including progressive respiratory failure due to alveolar damage and acute respiratory distress syndrome (ARDS). Pathological changes in SARS suggest that SARS sequelae such as infiltration of PMN in lung tissue, multiple organ dysfunction and ARDS have been associated with cytokines and chemokine dysregulation. Some patients still manifested lung injury at a time when the viral load was falling also supports the immune nature of the lung damage. We therefore undertook an analysis of dynamic production of ...https://clinicaltrials.gov/ct2/show/record/NCT00173459
Figure 3 - Severe Acute Respiratory Syndrome: Clinical Outcome and Prognostic Correlates1 - Volume 9, Number 9-September 2003 -...
Severe acute respiratory syndrome (SARS) poses a major threat to the health of people worldwide. We performed a retrospective case series analysis to assess clinical outcome and identify pretreatment prognostic correlates of SARS, managed under a standardized treatment protocol. We studied 127 male and 196 female patients with a mean age of 41±14 (range 18-83). All patients, except two, received ribavirin and steroid combination therapy. In 115 (36%) patients, the course of disease was limited. Pneumonitis progressed rapidly in the remaining patients. Sixty-seven (21%) patients required intensive care, and 42 (13%) required ventilator support. Advanced age, high admission neutrophil count, and high initial lactate dehydrogenase level were independent correlates of an adverse clinical outcome. SARS-associated coronavirus caused severe illnesses in most patients, despite early treatment with ribavirin and ...https://wwwnc.cdc.gov/eid/article/9/9/03-0362-f3
Severe acute respiratory syndrome - Simple English Wikipedia, the free encyclopedia
Severe acute respiratory syndrome (SARS)  was an atypical pneumonia. It started in November 2002 in Guangdong Province, in the city of Foshan, of the People's Republic of China. The disease was caused by the SARS coronavirus (SARS CoV), a new coronavirus. It was also a part-time STD, it can be spread through both sexual and casual contact. SARS was first reported in Asia in February 2003. Over the next few months, the illness spread to more than 24 countries in Asia, North America, South America, and Europe before the SARS global outbreak of 2003 was contained. According to the World Health Organization (WHO), a total of 8098 people worldwide became sick with SARS during the 2003 outbreak; 774 of these died. After the Chinese government suppressed news of the SARS outbreak, the disease spread rapidly, reaching Hong Kong and Vietnam in late February 2003, and then to other countries via international travellers. The last case in this ...https://simple.wikipedia.org/wiki/Severe_acute_respiratory_syndrome
Synthesis inEscherichia colicells and characterization of the active exoribonuclease of severe acute respiratory syndrome...
The nsp14 protein, an exoribonuclease of the DEDD superfamily encoded by severe acute respiratory syndrome coronavirus (SARS-CoV), was expressed in fusion with different affinity tags. The recombinanthttps://link.springer.com/article/10.1134%2FS0026893309030091
Severe Acute Respiratory Syndrome (SARS) - Health, Disease, Quarantine, and Officials - JRank Articles
Severe acute respiratory syndrome (SARS) is the first emergent and highly transmissible viral disease to appear during the twenty-first century. Patients with SARS develop flu-like fever, headache, malaise, dry cough and other breathing difficulties. Many patients develop pneumonia, and in 5-10% of cases, the pneumonia and other complications are severe enough to cause death. SARS is caused by a virus that is transmitted usually from person to person-predominantly by the aerosolized droplets of virus infected material.. SARS cases provided a test of recent reforms in International Health Regulations designed to increase surveillance and reporting of infectious diseases-and to enhance cooperation in preventing the international spread of disease. Although not an act of bioterrorism, because the very same epidemiologic principles and isolation protocols might be used to both initially determine and initially ...http://science.jrank.org/pages/6085/Severe-Acute-Respiratory-Syndrome-SARS.html
The interferon gamma gene polymorphism +874 A/T is associated with severe acute respiratory syndrome | BMC Infectious Diseases ...
Severe acute respiratory syndrome (SARS) is an infectious disease caused by SARS coronavirus  with ,8000 cases and 774 deaths reported in 2003 . Much progress has been made in understanding SARS coronavirus but the pathogenesis is still unclear . It was reported that old age, diabetes mellitus and heart disease were risk factors for adverse prognosis of SARS [4-6], however, little is known about the contribution of genetic factors. We have demonstrated that genetic haplotypes associated with low serum mannose-binding lectin (MBL) were associated with SARS  and our findings were recently replicated . Recently, homozygotes for CLEC4M tandem repeats were reported to be less susceptible to SARS in Hong Kong Chinese .. Cytokines are known to be important in antiviral action. Interferon (IFN)-γ from T and natural killer (NK) cells is important in driving the T helper cell type 1 (Th1) responses. It also activates monocytes and ...https://bmcinfectdis.biomedcentral.com/articles/10.1186/1471-2334-6-82
Severe acute respiratory syndrome (SARS) | Go Ask Alice!
Dear Reader,. Thanks for the props! And glad to be of service.. SARS is a serious health concern, and it can be dangerous if you come into contact with it. However, you don't necessarily need to be concerned. The media grasped onto the sensationalized story of SARS because of its rapid spread made possible by the relatively new phenomenon of extensive and frequent world travel and the fast rate of transmission. Luckily the virus was quickly isolated and contained only months after its initial out-break.. SARS, which is an acronym for Severe Acute Respiratory Syndrome, is a contagious and sometimes fatal respiratory illness that is actually a severe form of pneumonia. It is caused by a strain of the coronavirus, which is also the family of viruses that causes the common cold. SARS first appeared in China in 2002, and within six weeks had spread worldwide. Within a month and a half, 8,000 people were infected ...http://www.goaskalice.columbia.edu/answered-questions/severe-acute-respiratory-syndrome-sars
WHO | WHO Global Conference on Severe Acute Respiratory Syndrome (SARS)
The WHO Global Conference on Severe Acute Respiratory Syndrome (SARS), was held in the Sunway Lagoon Resort Hotel, Persiaran Lagoon, Bandar Sunway, 46150, Petaling Jaya, Selangor Darul Ehsan, Kuala Lumpur, Malaysia on 17-18 June 2003.. ...http://www.who.int/csr/sars/conference/june_2003/en/
NIOSHTIC-2 Publications Search - 20024103 - Cluster of severe acute respiratory syndrome cases among protected health-care...
Infections among health-care workers (HCWs) have been a common feature of severe acute respiratory syndrome (SARS) since its emergence. The majority of these infections have occurred in locations where infection-control precautions either had not been instituted or had been instituted but were not followed. Recommended infection-control precautions include the use of negative-pressure isolation rohttps://www.cdc.gov/niosh/nioshtic-2/20024103.html
Outbreak of severe acute respiratory syndrome in Singapore and modifications in the anesthesia service  | ScholarBank@NUS
Liu, E.H., Koh, K.-F., Chen, F.-G. (2004-06). Outbreak of severe acute respiratory syndrome in Singapore and modifications in the anesthesia service . Anesthesiology 100 (6) : 1629-1630. ScholarBank@NUS Repository ...http://scholarbank.nus.edu.sg/handle/10635/132947
Outbreak of severe acute respiratory syndrome in Singapore and modifications in the anesthesia service  | ScholarBank@NUS
Liu, E.H.,Koh, K.-F.,Chen, F.-G. (2004). Outbreak of severe acute respiratory syndrome in Singapore and modifications in the anesthesia service . Anesthesiology 100 (6) : 1629-1630. ScholarBank@NUS Repository ...http://scholarbank.nus.edu.sg/handle/10635/30888
Social Support and Response to AIDS and Severe Acute Respiratory Syndrome - Volume 14, Number 5-May 2008 - Emerging Infectious...
Negative public reactions to emerging infectious diseases can adversely affect population health. We assessed whether social support was associated with knowledge of, worry about, and attitudes towards AIDS and severe acute respiratory syndrome. Our findings suggest that social support may be central to our understanding of public responses to emerging infectious diseases.https://wwwnc.cdc.gov/eid/article/14/5/07-1070_article
Severe Acute Respiratory Syndrome | Aventura Hospital & Medical Center | Aventura, FL
Learn more about Severe Acute Respiratory Syndrome at Aventura Hospital & Medical Center DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...https://aventurahospital.com/hl/?/38008/SARS&com.dotmarketing.htmlpage.language=1
Severe Acute Respiratory Syndrome | Good Samaritan Hospital
Learn more about Severe Acute Respiratory Syndrome at Good Samaritan Hospital DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...https://goodsamsanjose.com/hl/?/38008/sp
Severe Acute Respiratory Syndrome | JFK Medical Center | Atlantis, FL
Learn more about Severe Acute Respiratory Syndrome at JFK Medical Center DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...https://jfkmc.com/hl/?/38008/
Severe Acute Respiratory Syndrome --- Singapore, 2003
Five persons with probable SARS cases have been categorized as super spreaders of SARS. These patients appear to have infected , 10 HCWs, family and social contacts, or visitors to the health-care facilities where the patients were hospitalized. Case 1. A person aged 22 years visited Hong Kong for a shopping trip and resided at Hotel M during February 20--25. On February 25, the visitor developed a fever with a dry cough and, on March 1, was hospitalized on Ward 5A of TTSH with a patchy infiltrate on chest radiograph. The patient's platelet count was 105,000/mm3 (normal: 130,000--150,000/mm3); a white blood count was 3,800/mm3 (normal: 4,000/mm3). On March 4, the patient was transferred to the intensive-care unit (ICU) because of decreased blood oxygen saturation. During March 6--11, the patient was admitted to and remained in isolation on Ward 5A. On March 11, the patient was transferred to Ward 8A. This patient was directly linked to probable SARS infection in 21 persons (nine HCWs and 12 ...https://www.cdc.gov/mmwr/preview/mmwrhtml/mm5218a1.htm
北京大学医学部机构知识库(IR@PKUHSC): Use of clinical criteria and molecular diagnosis to more effectively monitor patients recovering after...
Fung, YWW,Lau, LT,Wong, FPF,et al. Use of clinical criteria and molecular diagnosis to more effectively monitor patients recovering after severe acute respiratory syndrome coronavirus infection[J]. CLINICAL INFECTIOUS DISEASES,2004,39(4):604-606 ...http://ir.bjmu.edu.cn/handle/400002259/59234
Toronto: City Creating 'Perfect Conditions' for TB -- Health Group - TheBody.com
While Toronto recovers from the lingering effects of its Severe Acute Respiratory Syndrome outbreak, health experts are worried the city is poised for an ...http://www.thebody.com/content/art28751.html
Deliberations and recommendations of the Pediatric Emergency... : Pediatric Critical Care Medicine
Despite difficult challenges during responses to the terrorist attacks of September 11, 2001, Hurricane Katrina, and the 2009 Pandemic Influenza A/H1N1 and severe acute respiratory syndrome outbreaks, no North American emergency to date has overwhelmed intensive care unit (ICU) services on a widespread basis since the modern development of the field of critical care. However, planners have recognized that in a future public health emergency we may not be so fortunate. To deal with very large emergencies involving many patients whose survival depends on immediate access to intensive care, an international Task Force for Mass Critical Care proposed recommendations in January 2007 to extend critical care resources for the adult population, referred to as the Emergency Mass Critical Care (EMCC) approach (1-5).. The EMCC approach triples critical care capabilities for a period of up to 10 days in a very large public health emergency by focusing ...http://journals.lww.com/pccmjournal/Fulltext/2011/11001/Deliberations_and_recommendations_of_the_Pediatric.1.aspx
NewYork-Presbyterian/Queens - Severe Acute Respiratory Syndrome (SARS)
SARS-CoV spreads from one person to another mainly through close contact with a SARS patient. When a person with SARS coughs or sneezes without covering his or her mouth, respiratory droplets containing living virus can spray up to 3 feet and invade the mucous membranes of another person. Individuals in close contact with someone with SARS are most at risk, which means they live or work with someone with SARS or have direct contact with the a person through kissing, hugging, or sharing eating utensils.. The virus also can spread when an individual touches an object with infectious droplets on it and then touches his or her mouth, nose, or eyes. It is not known whether SARS can spread more broadly through the air.. Research suggests that SARS patients are infectious only when they are experiencing symptoms, such as fever or cough. They are most infectious during their second week of illness. As a precaution, the CDC recommends that SARS patients stay in isolation at home or in the hospital to ...http://www.nyhq.org/diw/Content.asp?PageID=DIW007732&language=Korean
WHO | Cumulative Number of Reported Probable Cases of SARS
Notes:. Cumulative number of cases includes number of deaths.. As SARS is a diagnosis of exclusion, the status of a reported case may change over time. This means that previously reported cases may be discarded after further investigation and follow-up.. 1. The start of the period of surveillance has been changed to 1 November 2002 to capture cases of atypical pneumonia in China that are now recognized as being cases of SARS.. 2. A decrease in the number of cumulative cases and discrepancies in the difference between cumulative number of cases of the last and the current WHO update are attributed to the discarding of cases.. 3. Includes cases who are "discharged" or "recovered" as reported by the national public health authorities.. 4. The date of onset of the most recent probable SARS case in Canada was 12 June, the last date of isolation of a probable SARS case was also 12 June.. 5. The date of onset of the most recent probable SARS case in China was 3 June 2003. The date of isolation of this ...http://www.who.int/csr/sars/country/2003_07_04/en/
Severe acute respiratory syndrome - Wikipedia
The SARS epidemic appears to have started in Guangdong Province, China in November 2002 where the first case was reported that same month. The patient, a farmer from Shunde, Foshan, Guangdong, was treated in the First People's Hospital of Foshan. The patient died soon after, and no definite diagnosis was made on his cause of death. Despite taking some action to control it, Chinese government officials did not inform the World Health Organization of the outbreak until February 2003. This lack of openness caused delays in efforts to control the epidemic, resulting in criticism of the People's Republic of China from the international community. China has since officially apologized for early slowness in dealing with the SARS epidemic.. The outbreak first appeared on 27 November 2002, when Canada's Global Public Health Intelligence Network (GPHIN), an electronic warning system that is part of the World Health Organization's Global Outbreak Alert and Response Network (GOARN), picked up reports of ...https://en.m.wikipedia.org/wiki/Severe_acute_respiratory_syndrome
Transmission of severe acute respiratory syndrome (SARS)
SARS is mainly spread by close person-to-person contact. After two to seven days, SARS patients may develop a dry cough with most developing pneumonia.http://respiratory-lung.health-cares.net/sars-transmission.php