Pegylated Interferon Therapy for Acute Hepatitis C Infection in HIV-infected Patients - Full Text View - ClinicalTrials.gov
... be withheld for 12 weeks in order to allow spontaneous resolution in subjects with clinical symptomatic hepatitis C infection. ... Hepatitis. Hepatitis A. Hepatitis C. HIV Infections. Liver Diseases. Digestive System Diseases. Hepatitis, Viral, Human. Virus ... Enterovirus Infections. Picornaviridae Infections. RNA Virus Infections. Flaviviridae Infections. Lentivirus Infections. ... There is basic research and clinical data on hepatitis C mono-infection supporting high sustained response rates of hepatitis C ...https://clinicaltrials.gov/show/NCT00132210
Abiraterone, Radiotherapy and Short-Term Androgen Deprivation in Unfavorable Localized Prostate Cancer - Full Text View -...
Clinical evidence of active infection of any type, including active or symptomatic viral hepatitis. ... Chronic liver disease with cirrhosis (Child-Pugh B or C) or active hepatitis B or C ... Gleason Score 7 with PSA ≤ 20 ng/ml and clinical T1-2, or ... Clinical T3 with Gleason Score , 7 and PSA ≤ 10 ng/ml.. *ECOG ... Gleason Score 8-10, PSA ≤ 20 ng/ml and clinical T1-2a, or ... PSA 10.1-40 ng/ml with GS , 7 and clinical T1-2, or ...https://clinicaltrials.gov/ct2/show/NCT01717053
Recommendations for Postexposure Interventions to Prevent Infection with Hepatitis B Virus, Hepatitis C Virus, or Human...
... have initial clinical signs or symptoms (11). The fatality rate among persons with reported cases of acute symptomatic ... exists for acute hepatitis B. Acute hepatitis B infection fails to resolve and instead progresses to chronic HBV infection in ... This report outlines recommendations for postexposure interventions to prevent infection with hepatitis B virus, hepatitis C ... Recommendations for Postexposure Interventions to Prevent Infection with Hepatitis B Virus, Hepatitis C Virus, or Human ...https://www.cdc.gov/MMWR/preview/mmwrhtml/rr5706a1.htm
Viral Infections and Pregnancy: Background, Clinical Presentation, Workup
Infections can develop in the neonate transplacentally, perinatally (from vaginal secretions or blood), or postnatally (from ... Viral infections in pregnancy are major causes of maternal and fetal morbidity and mortality. ... Clinical course of pregnant women with chronic hepatitis C virus infection and risk of mother-to-child hepatitis C virus ... Primary infection demonstrates a more severe symptomatic picture. One third of patients with primary infection report multiple ...https://emedicine.medscape.com/article/235213-overview
Find a Clinical Trial | NIH: National Institute of Allergy and Infectious Diseases
... and people with deficient immune systems are more vulnerable to symptomatic infection. NIAID researchers are exploring how ... Hepatitis. Hepatitis C Clinical Research Studies You can help NIAID advance hepatitis research by volunteering to participate ... Patient's Guide to Clinical Trials. Get answers to your questions about participating in clinical trials including:. *What are ... Investigator-Initiated Clinical Trial Resources *Prior Consultation Timeframes Clinical Trial Applications. *Requesting Prior ...https://www.niaid.nih.gov/clinical-trials/find-a-clinical-trial
A Comprehensive Immunization Strategy to Eliminate Transmission of Hepatitis B Virus Infection in the United States:...
Epidemiology of viral hepatitis and HIV co-infection. J Hepatol 2006;44(1 Suppl):S6--9. * Horvath J, Raffanti SP. Clinical ... HBV infection can produce either asymptomatic or symptomatic infection. The average incubation period is 90 days (range: 60-- ... Prevention of perinatally transmitted hepatitis B virus infections with hepatitis B virus infections with hepatitis B immune ... Hepatitis B vaccination is the most effective measure to prevent hepatitis B virus (HBV) infection and its consequences, ...https://www.cdc.gov/mmwr/preview/mmwrhtml/rr5516a1.htm?s_cid=rr5516a1_e
A Study of The Effect of Aleglitazar on Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus Who Are Inadequately...
... hepatitis C or HIV infection. *Clinical evidence of anemia. *Symptomatic congestive heart failure (New York Heart Association ...https://clinicaltrials.gov/ct2/show/NCT01729403?recr=Open&cond=%22Diabetes+Mellitus%2C+Type+2%22&rank=13
The natural course of hepatitis C virus infection 18 years after an epidemic outbreak of non-A, non-B hepatitis in a...
1996) Clinical sequelae of hepatitis C aquired from injection drug use. West J Med 164:399-404. ... All four symptomatic patients were found to have liver cirrhosis. Two patients had a history of heavy alcohol consumption. One ... Hepatitis C is an infection with a variable course that can lead to chronic hepatitis, end stage liver disease, and ... 1996) Routes of infection, viremia, and liver disease in blood donors found to have hepatitis C virus liver infection. N Engl J ...http://gut.bmj.com/content/44/4/563
Peter Sarnow | Stanford Medicine Profiles
Hepatitis C virus (HCV) infection is a rapidly increasing global health problem with an estimated 170 million people infected ... For example, dengue virus (DENV) is a rapidly emerging pathogen causing an estimated 100 million symptomatic infections ... of liver-specific microRNA miR-122 by antisense locked nucleic acids and their use in combating hepatitis C virus in clinical ... Enhancement of hepatitis C viral RNA abundance by precursor miR-122 molecules RNA-A PUBLICATION OF THE RNA SOCIETY Cox, E. M., ...https://med.stanford.edu/profiles/peter-sarnow
Clinical Study to Evaluate the Maximum Tolerated Dose of BAY1000394 Given in a 3 Days on / 4 Days Off Schedule in Subjects With...
Active clinically serious infections of CTCAE , Grade 2 (CTCAE v4.02). *Symptomatic metastatic brain or meningeal tumors unless ... History of human immunodeficiency virus (HIV) infection or chronic hepatitis B or C ... Clinical Study to Evaluate the Maximum Tolerated Dose of BAY1000394 Given in a 3 Days on / 4 Days Off Schedule in Subjects With ... Clinical study to determine safety, tolerability, to measure how the drug is metabolized by the body and to determine the ...https://clinicaltrials.gov/ct2/show/NCT01188252
Recruiting for Participants: Active Head and Neck Cancer Clinical Trial | LillyTrialGuide.com
Participant must not have an active symptomatic fungal, bacterial or viral infection, including HIV or Hepatitis A, B, or C ... About Clinical Trials Considering Participation What to Expect Find a Trial Completed Trials ... All clinical trials have rules about who can participate. This section outlines some of those rules. Please contact a study ... Search for a Lilly clinical trial in your area Refine your results Modify your search ...https://www.lillytrialguide.com/en-US/studies/head-and-neck-cancer/jtji
DailyMed - EPCLUSA- velpatasvir and sofosbuvir tablet, film coated
In patients with serologic evidence of HBV infection, monitor for clinical and laboratory signs of hepatitis flare or HBV ... 5.1 Risk of Hepatitis B Virus Reactivation in Patients Coinfected with HCV and HBV 5.2 Serious Symptomatic Bradycardia When ... If you have ever had hepatitis B virus infection, the hepatitis B virus could become active again during or after treatment of ... 14 CLINICAL STUDIES 14.1 Description of Clinical Trials 14.2 Clinical Trials in Subjects without Cirrhosis and Subjects with ...https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7f30631a-ee3b-4cfe-866b-964df3f0a44f
A Phase II Clinical Trial to Study the Efficacy and Safety of a New Drug P276-00 in Treatment of Recurrent and/or Locally...
Subjects known to be suffering from infection with HIV, Tuberculosis, Hepatitis C or Hepatitis B ... Subjects with uncontrolled inter-current illness including, but not limited to active infection, symptomatic congestive heart ... A Phase II Clinical Trial to Study the Efficacy and Safety of a New Drug P276-00 in Treatment of Recurrent and/or Locally ... Safety evaluations by means of recording vitals, physical examination and lab investigations like hematology and clinical ...https://clinicaltrials.gov/ct2/show/NCT00824343
Open-Label, Dose-Escalating, Clinical and Pharmacokinetic Phase I Study of Lurbinectedin (PM01183) in Patients with Advanced...
The goal of this clinical research study is to find the highest tolerable dose of lurbinectedin (PM01183) that can be given to ... Active uncontrolled infection. -Myopathy or any clinical situation that causes significant and persistent elevation of CPK (, ... Symptomatic or unstable cardiac arrhythmias, and/or prolonged QT-QTc grade greater or equal to 2. -History of significant ... active chronic hepatitis). -Any other major illness that, in the Investigator's judgment, will substantially increase the risk ...https://www.mdanderson.org/patients-family/diagnosis-treatment/clinical-trials/clinical-trials-index/clinical-trials-detail.ID2010-0965.html
Sovaldi (Sofosbuvir Tablets): Side Effects, Interactions, Warning, Dosage & Uses
In patients with serologic evidence of HBV infection, monitor for clinical and laboratory signs of hepatitis flare or HBV ... Serious Symptomatic Bradycardia When Coadministered with Amiodarone [see WARNINGS AND PRECAUTIONS].. Clinical Trials Experience ... Hepatitis C Virus Transmission. Inform patients that the effect of treatment of hepatitis C infection on transmission is not ... Test all patients for evidence of current or prior HBV infection by measuring hepatitis B surface antigen (HBsAg) and hepatitis ...https://www.rxlist.com/sovaldi-drug.htm
A Clinical Study With Tremelimumab as Monotherapy in Malignant Mesothelioma - Full Text View - ClinicalTrials.gov
Symptomatic chronic inflammatory or autoimmune disease. *Active hepatitis B or C. *Clinically relevant cardiovascular disease, ... Uncontrolled active infections. *Other concurrent chemotherapy, immunotherapy, radiotherapy or investigational agents. *History ... A Clinical Study With Tremelimumab as Monotherapy in Malignant Mesothelioma. The safety and scientific validity of this study ... Clinical studies examining CTLA-4 blockade are providing convincing evidences on the immunobiological effects and on the ...https://clinicaltrials.gov/ct2/show/study/NCT01649024?view=record
March 30, 2018 | Moffitt
Testing for hepatitis C lags with baby boomers despite high infection rate ... The approval followed a national, two year clinical trial, co-led by Moffitt Cancer Center in Tampa, in which doctors ... with a high lifetime risk of developing a precursor condition can reduce the prevalence and specific mortality of symptomatic ... Infections Disease Advisor - March 30. Monica L. Kasting, Ph.D., from the H. Lee Moffitt Cancer Center in Tampa, Fla., and ...https://moffitt.org/newsroom/moffitt-in-the-news/2018/march-30-2018/
Immunological and clinical follow up of hepatitis C virus associated cryoglobulinaemic vasculitis | Annals of the Rheumatic...
1995) Cryoglobulinemia in chronic hepatitis C infection: prevalence, clinical manifestations, response to interferon treatment ... six month duration of symptomatic cryoglobulinaemia, presence of at least two symptoms of Meltzer's triad (purpura, arthralgia ... 1996) Serum levels of soluble CD30 in chronic hepatitis B virus infection. Clin Exp Immunol 103:105-110, . ... clinical monitoring. Hepatitis C virus associated cryoglobulinaemic vasculitis (HCV associated CV) is an immune complex ...http://ard.bmj.com/content/60/4/385
Active or symptomatic infection including HIV, viral hepatitis or chronic liver disease 4. Any chronic medical condition ... Clinical Trials * Centers of Excellence Curated by expert editors: a single source educational forum with lectures, literature ... Known active HIV, Hepatitis B, or Hepatitis C infections. *Known or suspected hypersensitivity to seviteronel, or any ... Symptomatic Atrial Fibrillation, or other symptomatic cardiac arrhythmia 17. Other malignancy, except non-melanoma skin cancer ...https://www.urotoday.com/clinical-trials/prostate-cancer.html
Neurocysticercosis and epilepsy in developing countries | Journal of Neurology, Neurosurgery & Psychiatry
Symptomatic neurocysticercosis usually results from host inflammatory response after parasite death, and the clinical ... 1994) HLA and hepatitis B infection. Lancet 344:1194-1195.. OpenUrlCrossRefPubMedWeb of Science ... CLINICAL PRESENTATION. There are wide variations of clinical manifestations of neurocysticercosis. These are a consequence of ... 28-30 It is hypothesised that HLA differences might also determine the risk of intracranial infection or symptomatic ...http://jnnp.bmj.com/content/68/2/137
Reactivation of Hepatitis B Virus After Steroid Treatment in Rheumatic Diseases | The Journal of Rheumatology
The clinical or laboratory features of acute infection with hepatitis A virus, hepatitis C virus, and hepatitis E virus were ... He was started on symptomatic and supportive treatment for liver dysfunction along with highly active antiretroviral therapy ( ... Clinical or laboratory features of acute infection with hepatitis A virus, C virus, and E virus were absent. No information was ... Hepatitis B virus (HBV) infection is a global problem and is particularly endemic in some regions of the world. More than one- ...http://www.jrheum.org/content/38/1/181
Regorafenib in Metastatic Colorectal Cancer - Mayo Clinic
Known history of human immunodeficiency virus infection or current chronic/active hepatitis B or C infection. ... Research and Clinical TrialsSee how Mayo Clinic research and clinical trials advance the science of medicine and improve ... Ongoing infection > grade 2. *Symptomatic metastatic brain or meningeal tumors. *Presence of non-healing wound, non-healing ... Describes the nature of a clinical study. Types include:. *Observational study - observes people and measures outcomes without ...http://www.mayo.edu/research/clinical-trials/cls-20150039
A Phase 1 Study Evaluating the Safety and Pharmacokinetics of ABT-348 as monotherapy, and in combination with azacitidine, in...
The goal of this clinical research study is to find the highest tolerable dose of ABT-348 that can be given alone or with ... 11) Subject has infection with HIV, Hepatitis B, or Hepatitis C.. 12) Female subjects who are pregnant or breast feeding.. 13) ... Clinical Trials As part of our mission to eliminate cancer, MD Anderson researchers conduct hundreds of clinical trials to test ... 14) Clinically significant uncontrolled condition(s) including but not limited to: Active uncontrolled infection; Symptomatic ...https://www.mdanderson.org/patients-family/diagnosis-treatment/clinical-trials/clinical-trials-index/clinical-trials-detail.ID2009-0788.html
Comparison of Interferon-Gamma (IFNG) +874 T/A Single Nucleotide Polymorphism in Hepatitis C Virus Infected Patients and Non...
... infection. Methods: Between January and December 2012, 87 HCV-infected individuals and 89 individuals without HCV infection ... Carriers of A allele were more frequent in patients with HCV infection compared to the control group (55.17% in patients versus ... the genotypes at this position did not show any statistically significant association with HCV infection (adjusted P values ... including genetic variations of cytokine-producing genes have been shown to influence the progression and severity of Hepatitis ...http://ijp.iranpath.org/article_25046_3968.html
SASLT Practice Guidelines: Management of Hepatitis C Virus Infection
CLINICAL FEATURES OF HCV INFECTION. Infection with HCV can result in both acute and chronic hepatitis, each with a different ... Treatment of refractory, symptomatic, hepatitis C virus related mixed cryoglobulinaemia with ribavirin and interferon- alpha. J ... TREATMENT OF ACUTE HEPATITIS C. Identification of clinical acute HCV infection is uncommon, since, most of the time it has a ... EASL Clinical Practice Guidelines: Management of hepatitis C virus infection. J Hepatol. 2011;55:245-64. [PubMed] ...http://pubmedcentralcanada.ca/pmcc/articles/PMC3713589/?lang=en-ca
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