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*  Interleukin 28 receptor, alpha subunit - Wikipedia
The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with ... beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A ... Interleukin 28 receptor, alpha subunit is a subunit for the interleukin-28 receptor. IL28RA is its human gene. ... IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral ...
  https://en.wikipedia.org/wiki/Interleukin_28_receptor,_alpha_subunit
*  Interleukin 10 receptor, beta subunit - Wikipedia
This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster ... 2003). "IL-28, IL-29 and their class II cytokine receptor IL-28R". Nat. Immunol. 4 (1): 63-8. doi:10.1038/ni873. PMID 12469119 ... 2003). "IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex". Nat. Immunol. 4 (1): ... 2004). "The T-cell lymphokine interleukin-26 targets epithelial cells through the interleukin-20 receptor 1 and interleukin-10 ...
  https://en.wikipedia.org/wiki/Interleukin_10_receptor,_beta_subunit
*  IL10RB gene - Genetics Home Reference - NIH
This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster ... interleukin 10 receptor subunit beta. Enable Javascript to view the expand/collapse boxes.. Open All Close All ... Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The ... The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active ...
  https://ghr.nlm.nih.gov/gene/IL10RB
*  IL22RA1 - Wikipedia
The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for ... beta (IL10RB/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 ... Interleukin 22 receptor, alpha 1 is a protein that in humans is encoded by the IL22RA1 gene. ... Shioya M, Andoh A, Kakinoki S, Nishida A, Fujiyama Y (March 2008). "Interleukin 22 receptor 1 expression in pancreas islets". ...
  https://en.wikipedia.org/wiki/IL22RA1
*  anti-IL22 Receptor alpha 1 antibody | GeneTex
... interleukin 22 receptor, alpha 1) for ELISA, ICC/IF, WB. Anti-IL22 Receptor alpha 1 pAb (GTX16978) is tested in Human samples. ... interleukin 22 receptor, alpha 1. Background. The protein encoded by this gene belongs to the class II cytokine receptor family ... beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 ... and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein ...
  http://www.genetex.com/IL22-Receptor-antibody-GTX16978.html
*  Interleukin 22 - Wikipedia
IL-22 is an α-helical cytokine. IL-22 binds to a heterodimeric cell surface receptor composed of IL-10R2 and IL-22R1 subunits. ... The crystallographic asymmetric unit contained two IL-22-sIL-22R1 complexes. IL-22 a member of a group of cytokines called the ... Pancreatic islets also express high levels of IL-22 receptor. It has been shown to induce islet beta cell regeneration. IL-22, ... a class of potent mediators of cellular inflammatory responses. It shares use of IL-10R2 in cell signaling with other members ...
  https://en.wikipedia.org/wiki/Interleukin_22
*  Recombinant Human IL10RB protein (ab126022) | Abcam
Cytokine receptor class II. *Cytokine receptor class II CRF2 4. *Cytokine receptor class-II member 4 ... IL-10R subunit beta. *IL-10R2. *IL-10RB. *IL10R2. *IL10RB. *Interleukin 10 receptor beta ... Belongs to the type II cytokine receptor family.. Contains 2 fibronectin type-III domains. ... Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IL29. ...
  http://www.abcam.com/recombinant-human-il10rb-protein-ab126022.html
*  Anti-IL10RB antibody (ab106282) | Abcam
Cytokine receptor class II CRF2 4 antibody. *Cytokine receptor class-II member 4 antibody ... IL-10R subunit beta antibody. *IL-10R2 antibody. *IL-10RB antibody. *IL10R2 antibody ... Interleukin 10 receptor beta antibody. *Interleukin-10 receptor subunit 2 antibody. *Interleukin-10 receptor subunit beta ... Expression of class II cytokine genes in children's skin.. Acta Derm Venereol 94:386-92 (2014). Read more (PubMed: 24284923) » ...
  http://www.abcam.com/il10rb-antibody-ab106282.html
*  BIOMARKERS FOR THE EARLY DETECTION OF AUTOIMMUNE DISEASES - Patent application
IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines Dysregulated production of IL6 and this receptor ... It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also ... 0064] Il6ra'' or "interleukin 6 receptor alpha subunit" is a potent pleiotropic cytokine that regulates cell growth and ... The protein encoded by this gene is a subunit of the receptor complex for IL6. The IL6 receptor is a protein complex consisting ...
  http://www.patentsencyclopedia.com/app/20120171221
*  Interleukin 10 - Wikipedia
It downregulates the expression of Th1 cytokines, MHC class II antigens, and co-stimulatory molecules on macrophages. It also ... alpha subunit. The receptor complex for IL-10 also requires the IL10R2 chain to initiate signalling. This ligand-receptor ... beta, -epsilon, -kappa, -omega), type-II (IFN-gamma) and type-III (IFN-lambda, also known as IL-28A, IL-28B, and IL-29). In ... also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. In humans, interleukin 10 is ...
  https://en.wikipedia.org/wiki/Interleukin_10
*  IL-28 R alpha/IFN-lambda R1 Antibody (NBP1-84381): Novus Biologicals
Cytokine receptor class-II member 12. *Cytokine receptor family 2 member 12 ... interleukin-28 receptor subunit alpha. *LICR2. *Likely interleukin or cytokine receptor 2 ... interleukin 28 receptor, alpha (interferon, lambda receptor). *interleukin 28 receptor, alpha. *interleukin or cytokine ... Expression of Type-III interferons (IFNlambdas) and their receptor in Sjogren's Syndrome. Clin. Exp. Immunol. Sep 10 2016 [PMID ...
  https://www.novusbio.com/products/il-28-r-alpha-ifn-lambda-r1-antibody_nbp1-84381
*  Janus kinase 1 - Wikipedia
"Signaling by type I and II cytokine receptors: ten years after". Curr. Opin. Immunol. 13 (3): 363-73. doi:10.1016/S0952-7915(00 ... 1991). "Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class ... Ueda T, Bruchovsky N, Sadar MD (March 2002). "Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK ... receptor beta chain important for association of Jak1 and Jak3. Jak1-independent functional recruitment of Jak3 to Il-2Rbeta". ...
  https://en.wikipedia.org/wiki/Janus_kinase_1
*  Interleukin 4 - Wikipedia
This receptor exists in 3 different complexes throughout the body. Type 1 receptors are composed of the IL-4Rα subunit with a ... IL-4 induces B-cell class switching to IgE, and up-regulates MHC class II production. IL-4 decreases the production of Th1 ... two cytokines with closely related biological functions. IL-4 has a compact, globular fold (similar to other cytokines), ... "The association of atopy with a gain-of-function mutation in the alpha subunit of the interleukin-4 receptor". N. Engl. J. Med ...
  https://en.wikipedia.org/wiki/Interleukin_4
*  Calcineurin - Wikipedia
There are three isozymes of the catalytic subunit, each encoded by a separate gene (PPP3CA, PPP3CB, and PPP3CC) and two ... Wang MG, Yi H, Guerini D, Klee CB, McBride OW (1996). "Calcineurin A alpha (PPP3CA), calcineurin A beta (PPP3CB) and ... The activated NFATc is then translocated into the nucleus, where it upregulates the expression of interleukin 2 (IL-2), which, ... Calcineurin is the target of a class of drugs called calcineurin inhibitors, which includes cyclosporin, voclosporin, ...
  https://en.wikipedia.org/wiki/Calcineurin
*  Browse our IL29 ELISA Kits
All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 ... STAT2 (show STAT2 ELISA Kits) recruits USP18 (show USP18 ELISA Kits) to the type I IFN receptor subunit IFNAR2 (show IFNAR2 ... The review focuses on the value of the type I and III interferon (show IFNA ELISA Kits) subtypes (alphas, beta and lambdas) as ... This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine ...
  https://www.antibodies-online.com/abstract/Interleukin+29+
*  A Review: Inflammatory Process in Alzheimer's Disease, Role of Cytokines
"Enhancement of beta-amyloid precursor protein transcription and expression by the soluble interleukin-6 receptor/interleukin-6 ... 2.6.1. Major Proinflammatory Cytokines. The cytokine class of inflammatory mediators is secreted by microglia and astrocytes ... "Two inhibitors of pro-inflammatory cytokine release, interleukin-10 and interleukin-4, have contrasting effects on release of ... and expression of the beta-subunit of S100 protein (S100β) by astrocytes, thereby establishing a self-propagating cycle [18, ...
  https://www.hindawi.com/journals/tswj/2012/756357/
*  Interleukin - Wikipedia
Interleukin 1 alpha and interleukin 1 beta (IL1 alpha and IL1 beta) are cytokines that participate in the regulation of immune ... "Cloning and characterization of an alternatively processed human type II interleukin-1 receptor mRNA". The Journal of ... Interleukin 12 (IL-12) is a disulphide-bonded heterodimer consisting of a 35kDa alpha subunit and a 40kDa beta subunit. It is ... Interleukin 4 (IL4) is produced by CD4+ T cells specialized in providing help to B cells to proliferate and to undergo class ...
  https://en.wikipedia.org/wiki/Interleukin
*  SMART: SCY domain annotation
Interleukin-8 (IL-8) belongs to a family of small, structurally related cytokines similar to platelet factor 4. It is produced ... It is suggested that the two alpha-helices form the binding site for the cellular receptor and that the specificity of IL-8, as ... Interleukin 8, the first chemokine to be characterized, was discovered nearly ten years ago. Today, more than 30 human ... lie on top of a six-stranded antiparallel beta-sheet platform derived from two three-stranded Greek keys, one from each monomer ...
  http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SCY&BLAST=DUMMY
*  IL22RA1 Gene - GeneCards | I22R1 Protein | I22R1 Antibody
Interleukin 22 Receptor Subunit Alpha 1, including: function, proteins, disorders, pathways, orthologs, and expression. ... The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for ... beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 ... Interleukin-22 receptor subunit alpha-1. Protein Accession:. Q8N6P7. Secondary Accessions: *A8K839 ...
  https://www.genecards.org/cgi-bin/carddisp.pl?id_type=entrezgene&id=58985
*  IFNLR1 Gene - GeneCards | INLR1 Protein | INLR1 Antibody
Interferon Lambda Receptor 1, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The ... Interleukin-28 Receptor Subunit Alpha 3 4 * Cytokine Receptor Class-II Member 12 3 4 ... beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A ... The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with ...
  http://www.genecards.org/cgi-bin/carddisp.pl?id_type=entrezgene&id=163702
*  Cytokines and Transcription Factors That Regulate T Helper Cell Differentiation: New Players and New Insights | SpringerLink
A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits. Proc Natl Acad Sci USA 93 ... Farrar JD, Asnagli H, Murphy KM: T helper subset development: Roles of instruction, selection, and transcription. J Clin Invest ... A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R. J ... Differential associations between the cytoplasmic regions of the interleukin-12 receptor subunits beta1 and beta2 and JAK ...
  https://link.springer.com/article/10.1023%2FA%3A1023381027062
*  Index of immunology articles - Wikipedia
... alpha Interleukin 8 receptor, beta Interleukin receptor Interleukin-1 receptor Interleukin-1 receptor family Interleukin-1 ... necrosis factor alpha Tumor necrosis factor receptor Tumor necrosis factors Type I cytokine receptor Type II cytokine receptor ... subunit Interleukin 34 Interleukin 35 Interleukin 6 Interleukin 7 Interleukin 7 receptorInterleukin 8 Interleukin 8 receptor ... protein Macrophage-activating factor Major histocompatibility complex Mannan-binding lectin MHC class I MHC class II MHC ...
  https://en.wikipedia.org/wiki/Index_of_immunology_articles
*  CDw210b (IL-10Rβ) antibodies, mouse - Primary antibodies - Antibodies - MACS Flow Cytometry - Products - Miltenyi Biotec
CDw210b is member of the type II cytokine receptor protein family and has an extracellular domain with two fibronectin type III ... Additional information: Clone REA856 displays negligible binding to Fc receptors. ... CDw210b is important for IL-10-mediated effects and is expressed on various cell types. ... also known as interleukin-10 receptor beta (IL-10Rβ), a subunit of the IL-10 receptor. ...
  https://www.miltenyibiotec.com/BE-en/products/macs-flow-cytometry/antibodies/primary-antibodies/cdw210b-il-10rb-antibodies-mouse-rea856-1-50.html
*  il1b - Interleukin-1 beta precursor - Oncorhynchus mykiss (Rainbow trout) - il1b gene & protein
T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen ... Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, ... Interleukin-1 beta. ,p>This subsection of the ,a href="http://www.uniprot.org/help/ptm_processing_section">,span class="caps"> ... help/subunit_structure' target='_top'>More...,/a>,/p>Subunit structurei. Monomer.By similarity ...
  http://www.uniprot.org/uniprot/Q9YGD3
*  Interleukin-22 is increased in multiple sclerosis patients and targets astrocytes | Journal of Neuroinflammation | Full Text
Identification of the IL-22 receptor subunit, IL-22R1, was performed by immunohistochemistry and immunofluorescence in human ... interleukin-22 (IL-22), a Th17-linked cytokine, has been implicated in blood brain barrier breakdown and lymphocyte ... Using immunohistochemistry and confocal microscopy, we found that IL-22 and its receptor were detected on astrocytes of brain ... this cytokine confers an increased survival of the latter cells. ... 2) the cerebrospinal fluid, and (3) immune cells of peripheral ...
  https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-015-0335-3