*  Primary Cilia: The Chemical Antenna Regulating Human Adipose-Derived Stem Cell Osteogenesis - Semantic Scholar
Immunostaining of the primary cilium structure indicated phenotypic-dependent changes in cilia morphology. hASC cultured in ... indicating cilia-sensitivity to the chemical environment and a relationship between the cilium structure and phenotypic ... To elucidate cilia-mediated mechanisms of hASC differentiation, siRNA knockdown of PC1, PC2 and IFT88 was performed to disrupt ... Here we explore the role of primary cilia in human ASC (hASC) differentiation. This study focuses on the chemosensitivity of ...
  https://www.semanticscholar.org/paper/Primary-Cilia-The-Chemical-Antenna-Regulating-Huma-Bodle-Rubenstein/79b536d35747d44843502ef780520ea4f85fdd4c
*  Ion channels as new regulators of renal ciliogenesis | Journal of Cell Science
Review - Maintaining centrosomes and cilia. Centrosomes and cilia are essential structures for many functions in development ... Primary cilia are important for the development and physiology of many different organs, and numerous diseases have been linked ... As shown here, these channels all localise to the base of renal primary cilia and are required for ciliogenesis. KCNQ1 is of ... Indeed, the authors show that LQTS disease alleles affect renal ciliogenesis, pointing to a role for primary cilia in its ...
  http://jcs.biologists.org/content/128/24/e2404
*  Search Results - - 3,321 Results - Digital Library
The mitogenic effects of sonic hedgehog require primary cilia, but the few reports on glial or pericyte primary cilia do not ... it appears that resorption of cilia due to cell cycle entry may account for much of the loss of cilia in polydendrocytes but ... Effects of Brain Brain Injury on Primary Cilia of Glial Cells and Pericytes Description: Glial cells maintain homeostasis that ... Primary cilia are microtubule-based organelles that arise from the centrosome and are retracted before cells divide. Depending ...
  https://digital.library.unt.edu/explore/collections/UNTETD/browse/?fq=untl_institution%3AUNT&fq=untl_decade%3A2010-2019&start=930
*  C2cd3 is required for cilia formation and Hedgehog signaling in mouse | Development
C2cd3, cilia formation and cilia-related human genetic diseases. The formation of functional cilia is a complex process and ... we sought to determine whether C2cd3 also plays a role in the formation of cilia. Primary cilia (node cilia) are present on all ... B) In Hty mutants, most node cells do not have cilia. (C) In C2cd3GT mutants, cilia are absent from nearly all cells. (D) Wild- ... 7A). In Hty mutants, cilia failed to form in most cells in the node (Fig. 7B). In C2cd3GT mutant embryos, cilia were absent in ...
  http://dev.biologists.org/content/135/24/4049
*  Centrosomal protein of 290 kDa
Involved in early and late steps in cilia formation. Its association with CCP110 is required for inhibition of primary cilia ... A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.. 26477546. 2015. Joubert Syndrome in French ... May play a role in controlling entry of the BBSome complex to cilia possibly implicating IQCB1/NPHP5 (PubMed:25552655). ... Required for efficient recruitment of RAB8A to primary cilium (PubMed:17705300). In the ciliary transition zone is part of the ...
  https://pharos.nih.gov/idg/targets/O15078
*  Molecular Pathways: The Role of Primary Cilia in Cancer Progression and Therapeutics with a Focus on Hedgehog Signaling |...
We will discuss why some of the Hh inhibitors may be ineffective if primary cilia are lost on cancer cells. Understanding the ... Molecular Pathways: The Role of Primary Cilia in Cancer Progression and Therapeutics with a Focus on Hedgehog Signaling. Nadia ... It is in the primary cilium that both positive and negative effectors of the Hh pathway are processed by post-translational ... In many cancers, preliminary results suggest that primary cilia are lost. As drugs are developed that inhibit different steps ...
  http://clincancerres.aacrjournals.org/content/early/2012/03/15/1078-0432.CCR-11-0755
*  Alpha Omega Alpha - 2014 Research Abstract
Cilia are essential components of multiple organ systems. Inherited defects in ciliogenesis, the formation of cilia, are often ... which is part of a cilia motility regulator complex, from the cilia basal body into the ciliary membrane. To test these ... Our work will help lead to the recognition of new phenotypes of genetic and acquired cilia disorders that are based on ... While the role of IFTs in ciliogenesis has been established, the specific role IFT88 plays in airway cilia structure and ...
  http://alphaomegaalpha.org/student_research_abstract_turner
*  Cells | Free Full-Text | Photoreceptor Sensory Cilium: Traversing the Ciliary Gate
In the retina of the eye, photoreceptors develop unique sensory cilia. Not much was known about the mechanisms underlying the ... Here, I will discuss the studies that have revealed new knowledge of how photoreceptor cilia regulate their identity and ... Cilia are antenna-like extensions of the plasma membrane found in nearly all cell types. ... formation and function of photoreceptor cilia, largely because of technical limitations and the specific structural and ...
  http://www.mdpi.com/2073-4409/4/4/674
*  Dopamine Receptor Type 5 in the Primary Cilia Has Dual Chemo- and Mechano-Sensory Roles | Hypertension
Vascular endothelial primary cilia are known to function as mechano-sensory organelles. Although both primary cilia and ... which colocalizes to primary cilia in cultured cells and mouse arteries in vivo. DR5 activation increases cilia length in ... Dopamine Receptor Type 5 in the Primary Cilia Has Dual Chemo- and Mechano-Sensory Roles. Shakila Abdul-Majeed, Surya M. Nauli ... To determine the roles of the dopaminergic system and mechano-sensory cilia, we studied the effects of dopamine on ciliary ...
  http://hyper.ahajournals.org/content/early/2011/06/27/HYPERTENSIONAHA.111.172080
*  Brooks ER and Wallingford JB (2013), The Small GTPase Rsg1 is important for the cyto... - Xenbase Paper
Article link: Cilia. Genes referenced: fuz ift20 ift43 map7 mcc plin1 rsg1 Morpholinos referenced: rsg1 MO1 References: Arts, ... Cilia. January 1, 2013; 2 13. The Small GTPase Rsg1 is important for the cytoplasmic localization and axonemal dynamics of ... Cilia are small, microtubule-based protrusions important for development and homeostasis. We recently demonstrated that the ... Finally, we show that Rsg1 governs the apical localization of basal bodies, the anchoring structures of cilia. Our data suggest ...
  http://www.xenbase.org/literature/article.do?method=display&articleId=49533
*  Jeremy Reiter, MD, PhD | Biomedical Sciences Graduate Program
How do cells regulate whether they form a cilium?. This work has begun to suggest that the primary cilium is an organelle ... Do cilia transduce intercellular signals other than Hedgehog?. *How do cilia interpret signals essential to vertebrate ... Photoreceptors and odorant receptors function on primary cilia, and primary cilia are essential for sound reception. Therefore ... Eukaryotic cilia and flagella are cellular structures familiar to schoolchildren everywhere for the elegant swath they cut as ...
  http://bms.ucsf.edu/faculty/jeremy-reiter-md-phd
*  Individually Controllable Magnetic Cilia: Mixing Application | Journal of Medical Devices | ASME DC
e) The cured Fe-PDMS sheet is sliced to make cilia. (f) A rectangular PDMS chamber is cut where each cilium is to be mounted. ( ... i)-(j) When the magnet moves too far from the cilium to overcome elastic forces, the cilium straightens and snaps back to its ... As the cilium deflects, fluid is drawn into the expanding area to its left. (e)-(h) In these four images, the cilium touches ... to create a gap between the cilium and the slide and ensure the cilium will be parallel to the slide. (i) A final curing step ...
  http://medicaldevices.asmedigitalcollection.asme.org/article.aspx?articleid=2604693
*  A Partner for Smoothened in Cilia | Science Signaling
Primary cilia are critical for Hedgehog (Hh) signaling in vertebrates, and defects in Hh signaling or cilium structure cause ... report that the cilium-localized protein Evc2 was required for Sonic hedgehog (Shh)-induced transcription of GLI1 in cultured ... K. V. Dorn, C. E. Hughes, R. Rohatgi, A Smoothened-Evc2 complex transduces the Hedgehog signal at primary cilia. Dev. Cell 23, ... Evc2 localized to a ring near the base of the cilium (the EvC zone) distal to the transition zone, which has been proposed to ...
  http://stke.sciencemag.org/content/5/248/ec281
*  The sensory cilia of Caenorhabditis elegans
The lengths of amphid cilia range from ∼7.5 μm (in the ASE, ASG, ASH, ASI, ASJ and ASK neurons) to ∼1.5 μm for the AFD cilium ( ... 1. General definition of cilia. 2. Historical perspective. 3. C. elegans cilia: distribution and architecture. 3.1. Amphids/ ... 4. Cilium biogenesis and intraflagellar transport (IFT). 5. Transcriptional regulation of cilium morphogenesis. 6. The C. ... Two types of cilia exist: motile cilia (alternatively termed flagella), which are used for locomotion or for the generation of ...
  http://dev.wormbook.org/chapters/www_ciliumbiogenesis/ciliumbiogenesis.html
*  Differential roles for 3-OSTs in the regulation of cilia length and motility | Development
Quantification of cilia length. 3-OST-5 MO1 injected embryos (1429 cilia, 29 embryos) had shorter cilia at 8 SS compared with ... 3-OST-5 is required for KV cilia length. (A,B) KV in uninjected (A) and 3-OST-5 MO1-injected (B) embryos at 8 SS. Cilia were ... Cilia were scored for the presence or absence of dynein arms (inner and outer); if a single dynein arm was present in a cilium ... 4D,E) and normal KV cilia number (51.11±10.47, n=18, P,0.99). This is in striking contrast to the short cilia phenotype in 3- ...
  http://dev.biologists.org/content/140/18/3892
*  Intraflagellar transport is essential for endochondral bone formation | Development
Loss of cilia and/or IFT in the AER and ventral ectoderm cells has no gross effect on limb patterning. As cilia are expressed ... By contrast, cilia were rarely observed on cells in the mesenchyme of conditional mutants (B). The presence of cilia on the ... 2E), whereas the ventral ectoderm of the same limb bud was nearly devoid of cilia (Fig. 2F). Despite the disruption of cilia on ... Cilia formation requires intraflagellar transport (IFT), and mutations disrupting the IFT process result in loss of cilia and ...
  http://dev.biologists.org/content/134/2/307
*  Human SAXO1 (FAM154A) is a microtubule-stabilizing protein specific to cilia and related structures | Journal of Cell Science
Review - Maintaining centrosomes and cilia. Centrosomes and cilia are essential structures for many functions in development ... Cilia and flagella are microtubule-based organelles present at the surface of most cells, ranging from protozoa to vertebrates ... Our data demonstrated that HsSAXO1 binds specifically to centriole and cilia microtubules. We identify, in vivo and in vitro, ... Although centrioles, cilia and flagella have cold-stable microtubules, MAP6 proteins have not been identified in these ...
  http://jcs.biologists.org/content/early/2015/02/10/jcs.155143
*  Cilia Motility
Cryo-electron tomography of motile cilia and flagella Cryo-electron tomography has been a valuable tool in the analysis of 3D ... Cilia Motility. Guest edited by Dr Hannah Mitchison, Dr David Mitchell, and Prof Heymut Omran ... Fifty years after the discovery of dyneins in motile cilia, much remains to be learned about the structure and mechanism of ... The motility of eukaryotic cilia and flagella is modulated in response to several extracellular stimuli. Ca2+ is the most ...
  https://www.biomedcentral.com/collections/CiliaMotility
*  Cilia - Conservapedia
Cilia cover the "foot" of a snail and are used to move the snail slowly along. Cilia are used for the slow locomotion of ... Within bivalves, cilia create a constant flow of water over various filtering and sorting surfaces and move and separate food ... Cilia are numerous short extensions of the plasma membrane used for locomotion and other purposes.[1] ... Most mucous membranes, such as those in the nose, are covered with cilia to create a constant flow of mucus. ...
  http://www.conservapedia.com/Cilia
*  PRIMARY CILIA
... The Green Hornet M.ROOS at AUCKLAND.AC.NZ Wed Nov 16 15:39:06 EST 1994 *Previous message: q:Vitronectin rec. ... IF YOU HAVE ANY HYPOTHESES REGARDING PRIMARY CILIA FUNCTION I WOULD LOVE TO HEAR THEM. REGARDS, GEORGE...... *Previous message ... I AM INVESTIGATING POSSIBLE ROLES OF PRIMARY CILIA USING CONFOCAL LASER MICROSCOPY WITH ANTIBODY LABELLING. ...
  http://www.bio.net/bionet/mm/cellbiol/1994-November/001157.html
*  Roles of primary cilia in hearing
... The roles of primary cilia in hearing. Summary. Cilia are antenna-like membrane-associated ... Alström Syndrome protein ALMS1 localizes to basal bodies of cochlear hair cells and regulates cilium-dependent planar cell ...
  http://www.ucl.ac.uk/ear/research/jaggerlab/projects/roles-of-primary-cilia-in-hearing
*  C�cilia Lyon
Platekompaniet - For å gi deg en bedre opplevelse av nettbutikken bruker Platekompaniet cookies. I innstillingene til din nettleser kan du selv velge å slette informasjonskapsler ...
  https://www.platekompaniet.no/medvirkende/ccilia-lyon/
*  Primary Cilia - QIAGEN
Primary Cilia RT2 Profiler PCR Array The Human Primary Cilia RT² Profiler PCR Array profiles the expression of 84 key genes ... Primary Cilia RT2 Profiler PCR Array The Mouse Primary Cilia RT² Profiler PCR Array profiles the expression of 84 key genes ... Primary Cilia RT2 Profiler PCR Array The Rat Primary Cilia RT² Profiler PCR Array profiles the expression of 84 key genes ... The single primary cilium found on the surface of almost all mammalian cell types is a non-motile sensory organelle with a 9+0 ...
  https://www.qiagen.com/ch/shop/genes-and-pathways/complete-biology-list/primary-cilia/
*  Cilia - Medical Dictionary / Glossary | Medindia
Cilia' - Eyelashes; or, microscopic hair-like projections lining the nose and bronchi, is clearly explained in Medindia s ... Cilia - Glossary. Written & Compiled by Medindia Content Team. Medically Reviewed by The Medindia Medical Review Team on May 07 ... Medical Word - Cilia. Ans : Eyelashes; or, microscopic hair-like projections lining the nose and bronchi. ...
  http://www.medindia.net/glossary/cilia.htm
*  Cilia Mathieu
E. cilia.mathieu@stibbe.com cilia.mathieu stibbe.com E-mail me ... Cilia Mathieu. Cilia Mathieu Junior Associate Brussels * T. +32 ...
  http://www.stibbe.com/en/people/c/cilia-mathieu