*  Primary Cilia: The Chemical Antenna Regulating Human Adipose-Derived Stem Cell Osteogenesis - Semantic Scholar
Immunostaining of the primary cilium structure indicated phenotypic-dependent changes in cilia morphology. hASC cultured in ... indicating cilia-sensitivity to the chemical environment and a relationship between the cilium structure and phenotypic ... To elucidate cilia-mediated mechanisms of hASC differentiation, siRNA knockdown of PC1, PC2 and IFT88 was performed to disrupt ... Here we explore the role of primary cilia in human ASC (hASC) differentiation. This study focuses on the chemosensitivity of ...
  https://www.semanticscholar.org/paper/Primary-Cilia-The-Chemical-Antenna-Regulating-Huma-Bodle-Rubenstein/79b536d35747d44843502ef780520ea4f85fdd4c
*  Ion channels as new regulators of renal ciliogenesis | Journal of Cell Science
Review - Maintaining centrosomes and cilia. Centrosomes and cilia are essential structures for many functions in development ... Primary cilia are important for the development and physiology of many different organs, and numerous diseases have been linked ... As shown here, these channels all localise to the base of renal primary cilia and are required for ciliogenesis. KCNQ1 is of ... Indeed, the authors show that LQTS disease alleles affect renal ciliogenesis, pointing to a role for primary cilia in its ...
  http://jcs.biologists.org/content/128/24/e2404
*  Search Results - - 3,321 Results - Digital Library
The mitogenic effects of sonic hedgehog require primary cilia, but the few reports on glial or pericyte primary cilia do not ... it appears that resorption of cilia due to cell cycle entry may account for much of the loss of cilia in polydendrocytes but ... Effects of Brain Brain Injury on Primary Cilia of Glial Cells and Pericytes Description: Glial cells maintain homeostasis that ... Primary cilia are microtubule-based organelles that arise from the centrosome and are retracted before cells divide. Depending ...
  https://digital.library.unt.edu/explore/collections/UNTETD/browse/?fq=untl_institution%3AUNT&fq=untl_decade%3A2010-2019&start=930
*  C2cd3 is required for cilia formation and Hedgehog signaling in mouse | Development
C2cd3, cilia formation and cilia-related human genetic diseases. The formation of functional cilia is a complex process and ... we sought to determine whether C2cd3 also plays a role in the formation of cilia. Primary cilia (node cilia) are present on all ... B) In Hty mutants, most node cells do not have cilia. (C) In C2cd3GT mutants, cilia are absent from nearly all cells. (D) Wild- ... 7A). In Hty mutants, cilia failed to form in most cells in the node (Fig. 7B). In C2cd3GT mutant embryos, cilia were absent in ...
  http://dev.biologists.org/content/135/24/4049
*  Centrosomal protein of 290 kDa
Involved in early and late steps in cilia formation. Its association with CCP110 is required for inhibition of primary cilia ... A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.. 26477546. 2015. Joubert Syndrome in French ... May play a role in controlling entry of the BBSome complex to cilia possibly implicating IQCB1/NPHP5 (PubMed:25552655). ... Required for efficient recruitment of RAB8A to primary cilium (PubMed:17705300). In the ciliary transition zone is part of the ...
  https://pharos.nih.gov/idg/targets/O15078
*  Molecular Pathways: The Role of Primary Cilia in Cancer Progression and Therapeutics with a Focus on Hedgehog Signaling |...
We will discuss why some of the Hh inhibitors may be ineffective if primary cilia are lost on cancer cells. Understanding the ... Molecular Pathways: The Role of Primary Cilia in Cancer Progression and Therapeutics with a Focus on Hedgehog Signaling. Nadia ... It is in the primary cilium that both positive and negative effectors of the Hh pathway are processed by post-translational ... In many cancers, preliminary results suggest that primary cilia are lost. As drugs are developed that inhibit different steps ...
  http://clincancerres.aacrjournals.org/content/early/2012/03/15/1078-0432.CCR-11-0755
*  Alpha Omega Alpha - 2014 Research Abstract
Cilia are essential components of multiple organ systems. Inherited defects in ciliogenesis, the formation of cilia, are often ... which is part of a cilia motility regulator complex, from the cilia basal body into the ciliary membrane. To test these ... Our work will help lead to the recognition of new phenotypes of genetic and acquired cilia disorders that are based on ... While the role of IFTs in ciliogenesis has been established, the specific role IFT88 plays in airway cilia structure and ...
  http://alphaomegaalpha.org/student_research_abstract_turner
*  Cells | Free Full-Text | Photoreceptor Sensory Cilium: Traversing the Ciliary Gate
In the retina of the eye, photoreceptors develop unique sensory cilia. Not much was known about the mechanisms underlying the ... Here, I will discuss the studies that have revealed new knowledge of how photoreceptor cilia regulate their identity and ... Cilia are antenna-like extensions of the plasma membrane found in nearly all cell types. ... formation and function of photoreceptor cilia, largely because of technical limitations and the specific structural and ...
  http://www.mdpi.com/2073-4409/4/4/674
*  Dopamine Receptor Type 5 in the Primary Cilia Has Dual Chemo- and Mechano-Sensory Roles | Hypertension
Vascular endothelial primary cilia are known to function as mechano-sensory organelles. Although both primary cilia and ... which colocalizes to primary cilia in cultured cells and mouse arteries in vivo. DR5 activation increases cilia length in ... Dopamine Receptor Type 5 in the Primary Cilia Has Dual Chemo- and Mechano-Sensory Roles. Shakila Abdul-Majeed, Surya M. Nauli ... To determine the roles of the dopaminergic system and mechano-sensory cilia, we studied the effects of dopamine on ciliary ...
  http://hyper.ahajournals.org/content/early/2011/06/27/HYPERTENSIONAHA.111.172080
*  Brooks ER and Wallingford JB (2013), The Small GTPase Rsg1 is important for the cyto... - Xenbase Paper
Article link: Cilia. Genes referenced: fuz ift20 ift43 map7 mcc plin1 rsg1 Morpholinos referenced: rsg1 MO1 References: Arts, ... Cilia. January 1, 2013; 2 13. The Small GTPase Rsg1 is important for the cytoplasmic localization and axonemal dynamics of ... Cilia are small, microtubule-based protrusions important for development and homeostasis. We recently demonstrated that the ... Finally, we show that Rsg1 governs the apical localization of basal bodies, the anchoring structures of cilia. Our data suggest ...
  http://www.xenbase.org/literature/article.do?method=display&articleId=49533
*  Jeremy Reiter, MD, PhD | Biomedical Sciences Graduate Program
How do cells regulate whether they form a cilium?. This work has begun to suggest that the primary cilium is an organelle ... Do cilia transduce intercellular signals other than Hedgehog?. *How do cilia interpret signals essential to vertebrate ... Photoreceptors and odorant receptors function on primary cilia, and primary cilia are essential for sound reception. Therefore ... Eukaryotic cilia and flagella are cellular structures familiar to schoolchildren everywhere for the elegant swath they cut as ...
  http://bms.ucsf.edu/faculty/jeremy-reiter-md-phd
*  Individually Controllable Magnetic Cilia: Mixing Application | Journal of Medical Devices | ASME DC
e) The cured Fe-PDMS sheet is sliced to make cilia. (f) A rectangular PDMS chamber is cut where each cilium is to be mounted. ( ... i)-(j) When the magnet moves too far from the cilium to overcome elastic forces, the cilium straightens and snaps back to its ... As the cilium deflects, fluid is drawn into the expanding area to its left. (e)-(h) In these four images, the cilium touches ... to create a gap between the cilium and the slide and ensure the cilium will be parallel to the slide. (i) A final curing step ...
  http://medicaldevices.asmedigitalcollection.asme.org/article.aspx?articleid=2604693
*  A Partner for Smoothened in Cilia | Science Signaling
Primary cilia are critical for Hedgehog (Hh) signaling in vertebrates, and defects in Hh signaling or cilium structure cause ... report that the cilium-localized protein Evc2 was required for Sonic hedgehog (Shh)-induced transcription of GLI1 in cultured ... K. V. Dorn, C. E. Hughes, R. Rohatgi, A Smoothened-Evc2 complex transduces the Hedgehog signal at primary cilia. Dev. Cell 23, ... Evc2 localized to a ring near the base of the cilium (the EvC zone) distal to the transition zone, which has been proposed to ...
  http://stke.sciencemag.org/content/5/248/ec281
*  The sensory cilia of Caenorhabditis elegans
The lengths of amphid cilia range from ∼7.5 μm (in the ASE, ASG, ASH, ASI, ASJ and ASK neurons) to ∼1.5 μm for the AFD cilium ( ... 1. General definition of cilia. 2. Historical perspective. 3. C. elegans cilia: distribution and architecture. 3.1. Amphids/ ... 4. Cilium biogenesis and intraflagellar transport (IFT). 5. Transcriptional regulation of cilium morphogenesis. 6. The C. ... Two types of cilia exist: motile cilia (alternatively termed flagella), which are used for locomotion or for the generation of ...
  http://dev.wormbook.org/chapters/www_ciliumbiogenesis/ciliumbiogenesis.html
*  Differential roles for 3-OSTs in the regulation of cilia length and motility | Development
Quantification of cilia length. 3-OST-5 MO1 injected embryos (1429 cilia, 29 embryos) had shorter cilia at 8 SS compared with ... 3-OST-5 is required for KV cilia length. (A,B) KV in uninjected (A) and 3-OST-5 MO1-injected (B) embryos at 8 SS. Cilia were ... Cilia were scored for the presence or absence of dynein arms (inner and outer); if a single dynein arm was present in a cilium ... 4D,E) and normal KV cilia number (51.11±10.47, n=18, P,0.99). This is in striking contrast to the short cilia phenotype in 3- ...
  http://dev.biologists.org/content/140/18/3892
*  Intraflagellar transport is essential for endochondral bone formation | Development
Loss of cilia and/or IFT in the AER and ventral ectoderm cells has no gross effect on limb patterning. As cilia are expressed ... By contrast, cilia were rarely observed on cells in the mesenchyme of conditional mutants (B). The presence of cilia on the ... 2E), whereas the ventral ectoderm of the same limb bud was nearly devoid of cilia (Fig. 2F). Despite the disruption of cilia on ... Cilia formation requires intraflagellar transport (IFT), and mutations disrupting the IFT process result in loss of cilia and ...
  http://dev.biologists.org/content/134/2/307
*  Human SAXO1 (FAM154A) is a microtubule-stabilizing protein specific to cilia and related structures | Journal of Cell Science
Review - Maintaining centrosomes and cilia. Centrosomes and cilia are essential structures for many functions in development ... Cilia and flagella are microtubule-based organelles present at the surface of most cells, ranging from protozoa to vertebrates ... Our data demonstrated that HsSAXO1 binds specifically to centriole and cilia microtubules. We identify, in vivo and in vitro, ... Although centrioles, cilia and flagella have cold-stable microtubules, MAP6 proteins have not been identified in these ...
  http://jcs.biologists.org/content/early/2015/02/10/jcs.155143
*  Cilia (entomology) - Wikipedia
Cilia (Latin for eyelashes; the singular is cilium) in entomology are fine hairs along the edges of the insect wing. Mosby's ...
  https://en.wikipedia.org/wiki/Cilia_(entomology)
*  Cilia Flores - Wikipedia
Cilia Flores (born in Tinaquillo, Cojedes, on 15 October 1953) is a Venezuelan lawyer and politician. She is married to the ... "Hijo de Cilia Flores pasa largas temporadas en los Estados Unidos". La Patilla. 12 January 2017. Retrieved 13 January 2017. Kay ... "Diputada Cilia Flores: daremos la pelea, aquí nadie se rinde". TeleSUR (in Spanish). 7 January 2016. Retrieved 9 January 2016. ... "Cilia Flores Maduro Bio". Daily Entertainment News. Retrieved April 13, 2013. Nelson, Brian A. (2009). The silence and the ...
  https://en.wikipedia.org/wiki/Cilia_Flores
*  Martin Cilia - Wikipedia
Martin Cilia Official Website Martin Cilia MySpace Revenge of the Surf Guitar MySpace Fender Website. ... Cilia played at the gig and Bosco told the other members from The Atlantics about him, and Cilla has been an integral and ... Cilia played his first gig in a school hall in Morley High in 1972 with fellow students. He remembered playing songs by The ... Cilia is an avid collector of classic and unique electric guitars. Some of his most valuable guitars can be heard on Revenge Of ...
  https://en.wikipedia.org/wiki/Martin_Cilia
*  Joe Cilia - Wikipedia
Joe Cilia at Soccerway Profile at Soccerpunter.com Joe Cilia at FootballDatabase.eu Joe Cilia manager stats at TheFinalBall.com ... Joseph "Joe" Cilia (22 October 1937 - 5 August 2017) was a Maltese professional football player and manager. In 1955-1956 ... Cilia died on 5 August 2017, aged 79. Joe Cilia at National-Football-Teams.com https://www.timesofmalta.com/mobile/articles/ ... view/20170805/sport/former-malta-stalwart-joe-cilia-passes-away.654956 ...
  https://en.wikipedia.org/wiki/Joe_Cilia
*  Santa Cilia - Wikipedia
Santa Cilia's history is linked to the Royal Monastery de San Juan de la Peña as far back as the 10th century. In 1336 "the ... Santa Cilia Somanés is a hamlet with 14 inhabitants that has been part of the municipality since 1969. It has a baroque 18th- ... Santa Cilia (in Aragonese: Santa Zilia) is a municipality located in Jacetania, province of Huesca, Aragon, Spain. It is 14 km ... Santa Cilia became a municipality in 1834 and attained its greatest population in 1920 with 520 inhabitants and about 90 houses ...
  https://en.wikipedia.org/wiki/Santa_Cilia
*  Trevor Cilia - Wikipedia
In 2015, Cilia was signed by Hamrun Spartans F.C.. Trevor Cilia at MaltaFootball.com Trevor Cilia at National-Football-Teams. ... Cilia won his first ever Premier League title in 2010 when, on 5 May he had the joy of lifting the cup for the first time. In ... Trevor Cilia was part of the 2009-2010 team for Birkirkara, where Birkirkara were crowned champions of the Maltese Premier ... Season 2009-2010 was a special one for Cilia as he was one of the most dangerous strikers of the season. With his daring runs ...
  https://en.wikipedia.org/wiki/Trevor_Cilia
*  Rémi Cilia - Wikipedia
Rémi Cilia at L'Équipe Football (in French) Rémi Cilia at FootballDatabase.eu Rémi Cilia at Soccerway. ... Rémi Cilia (born September 11, 1989 in Ollioules) is a French football player who last played for Toulon. ...
  https://en.wikipedia.org/wiki/R%C3%A9mi_Cilia
*  Cilia van Dijk - Wikipedia
"Interview Oscar-winnares Cilia van Dijk" [Interview with Oscar winner Cilia van Dijk]. historien.nl (in Dutch). Amsterdam. ... Cilia van Dijk-Lieshout (born 22 November 1941 in Uden) is a Dutch film producer. Her film work includes Frieze Frame, I Move, ...
  https://en.wikipedia.org/wiki/Cilia_van_Dijk