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*  Lipoprotein lipase - Wikipedia
It is a water-soluble enzyme that hydrolyzes triglycerides in lipoproteins, such as those found in chylomicrons and very low- ... While LPL is activated by ApoC-II, it is inhibited by ApoCIII. The LPL gene is highly conserved across vertebrates. Lipoprotein ... Through catalysis, VLDL is converted to IDL and then to LDL. Severe mutations that cause LPL deficiency result in type I ... NIH/UW entry on Familial Lipoprotein Lipase Deficiency Gene therapy for lipoprotein lipase deficiency Lipoprotein lipase at the ...
  https://en.wikipedia.org/wiki/Lipoprotein_lipase
*  A Polyglucuronic Acid to Target the FIAF Adipokine for Slimming Effects
... lipoprotein lipase and TG = triglycerides. As noted, the polyglucuronic acid was designed to simultaneously activate four ... intermediate density lipoproteins and high density lipoproteins (VLDL-IDL-HDL) at the peripheral tissues level and therefore at ... This renders the transport of fatty acids impossible by chylomicrons and very low density lipoproteins, ... Angiopoetin-like protein 4 converts lipoprotein lipase to inactive monomers and modumates lipase activity in adipose tissue, in ...
  http://www.cosmeticsandtoiletries.com/formulating/function/active/premium-A-Polyglucuronic-Acid-to-Target-the-FIAF-Adipokine-for-Slimming-Effects-211022481.html
*  Lipoprotein - Wikipedia
Examples include the plasma lipoprotein particles classified as HDL, LDL, IDL, VLDL and ULDL (a.k.a. chylomicrons) lipoproteins ... Via apolipoprotein C-II, mature chylomicrons activate lipoprotein lipase (LPL), an enzyme on endothelial cells lining the blood ... Hydrolysis by hepatic lipase releases glycerol and fatty acids, leaving behind IDL remnants, called low-density lipoproteins ( ... Again, like chylomicrons, VLDL particles circulate and encounter lipoprotein lipase (LPL) expressed on endothelial cells. ...
  https://en.wikipedia.org/wiki/Lipoprotein
*  Market Research on Nutraceutical Products | Cholesterol | Lipoprotein
lipoproteins have cell-targeting signals that direct the lipids they carry to certain tissues.cleavage-activating protein) and ... the blood vessel cleave and absorb more triacylglycerol from IDL molecules. which has an enzyme called lysosomal acid lipase ... the different lipoproteins contain apolipoproteins. Chylomicrons are the transporters that carry fats from the intestine to ... However.lipoprotein (IDL). During transport in the bloodstream. which serve as ligands for specific receptors on cell membranes ...
  https://www.scribd.com/doc/77286799/Market-Research-on-Nutraceutical-Products
*  Lipids | Encyclopedia.com
Functions of human plasma lipoproteins Lipoprotein class Origin Function Chylomicrons Intestine Transport lipids from intestine ... and ApoII is required for breakdown of the triglycerides by lipoprotein lipase. ... ApoAI activates lecithin-cholesterol acyltransferase, which is active in the synthesis of cholesterol esters, ... Intermediate density (IDL) VLDL Precursor of LDL High density (HDL 2 and 3) Intestine Remove cholesterol from tissues ...
  https://www.encyclopedia.com/science-and-technology/biochemistry/biochemistry/lipids
*  Enzyme Explorer Key Resources: Lipoprotein Function | China-Mainland | Sigma-Aldrich
Lipoprotein Function includes prducts, overview, classification, , properties and function. ... Chylomicrons *Very Low Density Lipoproteins (VLDL) *Intermediate Density Lipoproteins (IDL) *Low Density Lipoproteins (LDL) and ... Lipoprotein lipase also removes triglycerides from VLDL in the same way as from chylomicrons. ... LCAT is activated by apo-AI on HDL. HDL can acquire cholesterol from cell membranes and can transfer cholesteryl esters to VLDL ...
  https://www.sigmaaldrich.com/china-mainland/zh/life-science/metabolomics/enzyme-explorer/learning-center/plasma-blood-protein/lipoprotein-function.html
*  BioChem Flow Chart by Samir Al-Ayoubi on Prezi
50% IDL. APO C2. HDL. IDL. TAG = 3 FFA + glycerol. Lipoprotein. Lipase. APO C2. Type 4. HL. CAPILLARIES. CMRR. Chylomicron. ... Lipase. Type 3. HL. CAPILLARIES. 30% LDL. APO B100. (to circulation). LDLR. (liver entry). LIPOPROTEINS. EXTRACELLULAR. (bound ... attracts and activates. neutrophils). LTC-4. LTD-4. (Secondary-Delayed. response of Mast cells) ... Chylomicron. APO B48. HDL. APO C2. Lipoprotein. Lipase. APO C2. Type I. HL. TAG = 3 FFA + glycerol. Chylomicron Remnants. APO ...
  https://prezi.com/4uhdzf8t6qrl/biochem-flow-chart/
*  Cholesterol Transport | China-Mainland | Sigma-Aldrich
IDL) and then into low density lipoproteins (LDL). Lipoprotein lipase serves to remove the majority of fatty acids from both ... The largest and least dense lipoproteins are chylomicrons (see Figure 1). Chylomicrons predominately transport triacylglycerols ... LCAT is activated by apo-AI on HDL. HDL can acquire cholesterol from cell membranes and can transfer cholesteryl esters to VLDL ... Very low density lipoproteins (VLDL) are smaller and more dense than chylomicrons (see Figure 2). VLDLs contain ...
  https://www.sigmaaldrich.com/china-mainland/zh/technical-documents/articles/biofiles/cholesterol-transport.html
*  Fatty acid metabolism - Wikipedia
IDL), which is capable of scavenging cholesterol from the blood. This converts IDL into low-density lipoprotein (LDL), which is ... is carried out by lipases. These lipases are activated by high epinephrine and glucagon levels in the blood (or norepinephrine ... but known as very low-density lipoproteins (VLDL). These VLDL droplets are handled in exactly the same manner as chylomicrons, ... Lipoprotein lipase on the endothelial surfaces of the capillaries, especially in adipose tissue, but to a lesser extent also in ...
  https://en.wikipedia.org/wiki/Fatty_acid_metabolism
*  Studies on the antiatherogenic properties of liposomes - UBC Library Open Collections
... very low density lipoprotein (VLDL), intermediate density lipoproteins (IDL), low density lipoproteins (LDL), high density ... with apoCII playing a key role in activating lipoprotein lipase (LPL) which is located on the endothelial surface of capillary ... These include the chylomicrons, VLDL, IDL, LDL, HDL and VHDL (see text). Lipoproteins undergo a series of catalytic conversions ... HDL2 particles are reconverted to HDL3 particles by the action of lipoprotein lipase, and hepatic lipase which decrease both ...
  https://open.library.ubc.ca/cIRcle/collections/ubctheses/831/items/1.0099217
*  L24: Lipid Metabolism V Flashcards by Michael Renecle | Brainscape
modulate lipoprotein lipase (LPL) activity, which liberates FFAs and glycerol from lipoproteins ... They are transported inside of carriers known as lipoproteins - VLDL, IDL, LDL and HDL ... Chylomicrons in enterocytes associate with ApoB-48 - After entering into serum, CM now associates with ApoC and ApoE, which is ... Apoprotein A: activates LCAT (lecithin:cholesterol acyltransferase), which generates cholesterol esters from cholesterols. ...
  https://www.brainscape.com/flashcards/l24-lipid-metabolism-v-2700040/packs/4557570
*  Lipid Profile (Triglycerides): Reference Range, Interpretation, Collection and Panels
... mediated and cAMP-independent pathways that activate adipose triglyceride lipase, hormone-sensitive lipase, and ... which is a marker for TG chylomicron. These newly formed chylomicrons are then released from the enterocyte and transported to ... High triglyceride is a marker for elevated levels of atherogenic lipoproteins that contain triglyceride and FFA. [13] As ... 9] Following delipidation, a VLDL remnant (IDL) is formed, which has released the bulk of triglyceride originally packaged and ...
  https://emedicine.medscape.com/article/2074115-overview
*  Diacylglycerol lipase | definition of Diacylglycerol lipase by Medical dictionary
What is Diacylglycerol lipase? Meaning of Diacylglycerol lipase medical term. What does Diacylglycerol lipase mean? ... Looking for online definition of Diacylglycerol lipase in the Medical Dictionary? Diacylglycerol lipase explanation free. ... in chylomicrons, very-low-density lipoproteins, and low-density lipoproteins.. lipoprotein lipase (LPL). an enzyme that plays a ... It is activated by apolipoprotein C-II; a deficiency of lipoprotein lipase is associated with familial hyperlipoproteinemia ...
  http://medical-dictionary.thefreedictionary.com/Diacylglycerol+lipase
*  High-fat meal effect on LDL, HDL, and VLDL particle size and number in the Genetics of Lipid-Lowering Drugs and Diet Network ...
... high-density lipoprotein cholesterol; HL: hepatic lipase; IDL-C: intermediate-density lipoprotein; LDL-C: low-density ... 0/Cholesterol, VLDL; 0/Dietary Fats; 0/Lipoproteins, HDL; 0/Lipoproteins, IDL; 0/Lipoproteins, LDL; 0/Lipoproteins, VLDL; 0/ ... very low-density lipoprotein cholesterol (VLDL-C), and chylomicron concentrations; decreases in high-density lipoprotein ... Additionally, we did not obtain information on the activity level of enzymes and proteins that are known to be activated during ...
  http://www.biomedsearch.com/nih/High-fat-meal-effect-LDL/22008512.html
*  Disorders of Lipoprotein Metabolism | Greenspan's Basic & Clinical Endocrinology, 10e | AccessMedicine | McGraw-Hill Medical
Atherogenic lipoproteins include low-density (LDL), intermediate density (IDL), very low density lipoproteins (VLDL), and Lp(a ... species, all of which contain the B-100 apolipoprotein (Apo B-100). Chylomicron remnants containing apo B-48 are also ... Low-density lipoproteins. LMF1. Lipase maturation factor 1. Lp(a). Lipoprotein(a). ... The clinical importance of lipoprotein disorders derives chiefly from the role of lipoproteins in atherogenesis and its ...
  http://accessmedicine.mhmedical.com/content.aspx?bookid=2178§ionid=166252957
*  High-density lipoprotein - Wikipedia
Chylomicrons VLDL-C particiles IDL-C particles LDL-C particles HDL-C particle Lipoprotein (a) [LP(a)] Men tend to have ... High-density lipoproteins (HDL) are one of the five major groups of lipoproteins. Lipoproteins are complex particles composed ... "Sirtuin 1 Mediates the Actions of Peroxisome Proliferator-Activated Receptor δ on the Oxidized Low-Density Lipoprotein- ... When the body requires fatty acids as an energy source, the hormone glucagon signals the breakdown of the TGs by lipase to ...
  https://en.wikipedia.org/wiki/High-density_lipoprotein
*  EXAM #2: ANTIHYPERLIPIDEMICS Flashcards by Jonathan Kallevang | Brainscape
Cause: Defect in lipoprotein lipase (LPL) Effect: increased chylomicrons and VLDL. ******Recall that LPL breaksdown TGs in ... Effect: decreased clearance of VLDL, IDL, and chylomicrons remnants, resulting in increased IDL and chylomicrons ... For dietary lipids to be removed from the circulation, lipoprotein lipase (LPL) must be activated; this requires ApoC-II. **** ... How does the density and structure of the lipoproteins compare to one another? ...
  https://www.brainscape.com/flashcards/exam-2-antihyperlipidemics-4098159/packs/6029982
*  MCB II Block 4
Q: Is hepatic lipase activated by apoC-II?. A: No. Q: Besides converting IDL to LDL, what else does Hepatic Lipase do?. A: it ... Q: What is the biggest class of lipoprotein?. A: Chylomicrons are the biggest class of lipoproteins. They transport ... A: VLDL, IDL, and LDL. Q: Why are things like chylomicrons and VLDLs called "lipoproteins"?. A: because they carry lipids and ... A: chylomicrons.. Q: Descript lipoprotein transport?. A: Liver makes VLDL, which go to capillaries. Remnants become IDL, which ...
  http://www.caribbeanmedstudent.com/notes/mcb-ii-block-4/
*  Lipids and Lipoproteins in Patients With Type 2 Diabetes | Diabetes Care
CETP, cholesterol ester transfer protein; Chol, cholesterol; HL, hepatic lipase; LDLR, LDL receptor; LPL, lipoprotein lipase; ... Direct atherogenic effects of triglyceride-rich particles, especially IDL and remnant lipoproteins, may account for this ... Fibrates (peroxisome proliferator-activated receptor-α agonists). A major effect of peroxisome proliferator-activated receptor- ... An important consequence of retarded clearance is prolonged plasma retention of both VLDL and postprandial chylomicrons as ...
  http://care.diabetesjournals.org/content/27/6/1496
*  Free Medical Flashcards about biochem test 2 2011
apoCII activates lipoprotein lipase*** It comes form HDL's that transfer it to nascent chylomicrons and VLDL. ... ACAT in cells LCAT in lipoproteins. What are the primary conjugated bile salt? the secondary?. primary conj taurocholic, ... In genreal an increase in VLDL will increase IDL which in turn increased LDL. ... Glucagon and Epinephrine, phosporylation activates it.. What other lipase is under hormonal influence?. Lipoprotein lipase. ...
  https://www.studystack.com/flashcard-674385
*  Overproduction of Very Low-Density Lipoproteins Is the Hallmark of the Dyslipidemia in the Metabolic Syndrome |...
Triglyceride-rich VLDL is released from the liver and converted to IDL by lipoprotein lipase (LPL)-catalyzed hydrolyzation of ... Evidence for a common, saturable, triglyceride removal mechanism for chylomicrons and very low density lipoproteins in man. J ... Fibrates activate PPARα, which plays a key role in the regulation of energy homeostasis and inflammation.89 Fibrates have been ... Evidence that apolipoprotein CIII inhibits catabolism of triglyceride-rich lipoproteins by lipoprotein lipase in vivo. J Clin ...
  http://atvb.ahajournals.org/content/28/7/1225.long
*  Hyperlipidemia - Wikipedia
This form is due to high chylomicrons and IDL (intermediate density lipoprotein). Also known as broad beta disease or ... Lipoprotein lipase deficiency (type Ia), due to a deficiency of lipoprotein lipase (LPL) or altered apolipoprotein C2, ... Hyperlipidemia is abnormally elevated levels of any or all lipids or lipoproteins in the blood. It is the most common form of ... Both conditions are treated with fibrate drugs, which act on the peroxisome proliferator-activated receptors (PPARs), ...
  https://en.wikipedia.org/wiki/Hyperlipidemia
*  Macro Nutrients - Lipid Flashcards - Cram.com
3. They use apoC to activate LPL just like chylomicrons do 4. * Intermediate density lipoproteins (IDL) are left over. * also ... Lipoprotein lipase. * Found on the endothelial cells of capillaries in adipose tissue and muscle. * Removes fatty acids from ... 3. Chylomicrons, Very-Low Density-Lipoprotein (VLDL), Low-Density Lipoproteins (LDL), & High-Density Lipoproteins (HDL). 4. ... cAMP activates PKA. * ATP + PKA phosphorylate hormone-sensitive lipase. * Hormone-sensitive lipase acts on triacylglycerides ( ...
  http://www.cram.com/flashcards/macro-nutrients-lipid-316161
*  Peroxisome Proliferator-Activated Receptor Alpha Target Genes
... articles on advances in basic research focusing on mechanisms involved in the activation of peroxisome proliferator-activated ... Clearance of TG-rich lipoproteins VLDL and chylomicrons is mediated by the enzyme lipoprotein lipase (LPL), which is attached ... IDL, and HDL [230]. Whether Lipc represents a direct target gene of in human remains unclear. Other genes involved in ... R. Carroll and D. L. Severson, "Peroxisome proliferator-activated receptor-α ligands inhibit cardiac lipoprotein lipase ...
  https://www.hindawi.com/journals/ppar/2010/612089/
*  Influence of diet fat saturation on rates of cholesterol synthesis and esterification in healthy young men - UBC Library Open...
... and to the activities of lipoprotein lipase and hepatic lipase. J Clin Invest 80:341-347. Pattnaik NM, Montes A, Hughes LB, ... It is now known that CETP allows the CE of HDL to be transported to the liver by chylomicron remnants and IDL, or by hepatic ... Plasma lipoproteins were isolated, and the fatty acid composition of the lipoprotein fractions, including TG, CE, and PL, was ... The combined ether phases were dried down under nitrogen, and were then plated on activated thin layer silica plates, as ...
  https://open.library.ubc.ca/cIRcle/collections/ubctheses/831/items/1.0088878