Loading...
*  The Caenorhabditis elegans Dosage Compensation Machinery Is Recruited to X Chromosome DNA Attached to an Autosome | Genetics
1994 The human X-inactivation centre is not required for maintenance of X-chromosome inactivation. Nature 368: 154-156. ... The following oligonucleotide pairs were annealed to form double-stranded DNA and coinjected into worms along with the DNA ... 1981 Reactivation of an inactive human X chromosome: evidence for X inactivation by DNA methylation. Science 211: 393-396. ... mnDp10 is a duplication of the right end of X attached to chromosome I (see Figure 5). (B) The volume of the X chromosome ...
  http://www.genetics.org/content/156/4/1603
*  Variations on a theme: Genomics of sex determination in the cichlid fish Astatotilapia burtoni | BMC Genomics | Full Text
Evidence that the human X chromosome is enriched for male-specific but not female-specific genes. Mol Biol Evol. 2003;20(7): ... The best-studied form of GSD relies on a pair of sex chromosomes with one homolog carrying a master SD locus necessary for the ... LG5, the sex chromosome of the lab strain, is a fusion chromosome in A. burtoni. Wnt4 is located on this chromosome, ... Chromosome 5 is such a chromosome, which has evolved several times as a sex chromosome, both in haplochromine cichlids from all ...
  https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-016-3178-0
*  Homologous chromosome - Wikipedia
Humans have a total of 46 chromosomes, but there are only 22 pairs of homologous autosomal chromosomes. The additional 23rd ... pair is the sex chromosomes, X and Y. If this pair is made up of an X and Y chromosome, then the pair of chromosomes is not ... So humans have two homologous chromosome sets in each cell, meaning humans are diploid organisms. Homologous chromosomes are ... Therefore, when two chromosomes of the exact structure exist, they are able to pair together to form homologous chromosomes. ...
  https://en.wikipedia.org/wiki/Homologous_chromosome
*  Blank allele | definition of blank allele by Medical dictionary
Humans have two, usually identical, alleles for each gene, one on each AUTOSOMAL chromosome of a pair. ... one of two or more alternative forms of a gene at the same site or locus in each of a pair of chromosomes, which determine ... As autosomal chromosomes are paired, each autosomal gene is represented twice in normal somatic cells. If the same allele ... As autosomal chromosomes are paired, each autosomal gene is represented twice in normal somatic cells. If the same allele ...
  https://medical-dictionary.thefreedictionary.com/blank+allele
*  How yeast chromosomes avoid the bad breaks
Later, when the paired chromosomes are pulled apart, each resulting chromosome is a patchwork of maternal and paternal genes. ... How yeast chromosomes avoid the bad breaks. 08.08.2011. The human genome is peppered with repeated DNA elements that can vary ... During meiosis an organism's chromosomes pair up, with every pair containing a copy inherited from each of the organism's ... To match up the chromosomes, the cell breaks both strands of the chromosomes' DNA in multiple locations, and the chromosomes ...
  http://www.innovations-report.com/html/reports/life-sciences/yeast-chromosomes-avoid-bad-breaks-179831.html
*  Inbreeding and origin of races - creation.com
The information in twenty three chromosome pairs of a human is a sophisticated DNA program with an inheritance property. Even a ... evidence for a faster evolutionary rate of mtDNA lineages than Y chromosomes, American J. Human Genetics 72:1370-1388, 2003. ... Evidence for a faster evolutionary rate of mtDNA lineages than Y chromosomes, American J. Human Genetics 72:1370-1388, 2003. ... Quintana-Murci, L., Human variation chalked up to natural selection: study, PhysOrg.com, 4 February 2008. Return to text. ...
  https://creation.com/inbreeding-and-origin-of-races
*  Application # 2011/0245592. Secretome Profile-Facilitated In Vitro Fertilization - Patents.com
... of the haploid number for a human embryo, namely 23 pairs of chromosomes. [0046] In Tables 1 and 2 below, the entries for " ... HUMAN 16 kDa Q16695 D 1/D 3/D 5 316 Histone H1.3 H13_HUMAN 22 kDa P16402 D 3/D 5 317 Lysozyme C LYSC_HUMAN 17 kDa P61626 D 3/D ... HUMAN 139 kDa P02452 D 1/D 3 304 Cystatin-A CYTA_HUMAN 11 kDa P01040 D 1/D 3 305 Filaggrin FILA_HUMAN 435 kDa P20930 D 1/D 3 ... HUMAN 60 kDa P04040 D 5 333 Cathepsin D CATD_HUMAN 45 kDa P07339 D 5 334 CD44 antigen, isoform 1 CD44_HUMAN 81 kDa P16070 D 5 ...
  http://patents.com/us-20110245592.html
*  TAS2R16 - Wikipedia
The TAS2R16 gene is located on the long (q) arm of chromosome 7 at position 31.1 - 31.3, from base pair 122,228,764 to base ... "Human PubMed Reference:". "Mouse PubMed Reference:". Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (2002). "The human ... Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes". Mol. Biol. Evol. 22 (3): ... Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-specific loss of function of bitter taste receptor genes in humans and ...
  https://en.wikipedia.org/wiki/TAS2R16
*  Multisynthetase complex auxiliary component p38 - Wikipedia
The JTV1 gene is located on chromosome 7p22 flanked by two genes, HRI and PMS2. JTV1 and HRI overlap slightly and are arranged ... JTV1 and PMS2 are separated by approximately 200 base pairs and are arranged head-to-head. JTV1 is transcribed in the opposite ... October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. doi ... Human Molecular Genetics. 12 (12): 1427-37. doi:10.1093/hmg/ddg159. PMID 12783850. Kim MJ, Park BJ, Kang YS, Kim HJ, Park JH, ...
  https://en.wikipedia.org/wiki/Multisynthetase_complex_auxiliary_component_p38
*  CD99 - Wikipedia
"Homologous expressed genes in the human sex chromosome pairing region". Nature. 317 (6039): 739-41. doi:10.1038/317739a0. PMID ... CD99 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH) Human CD99 genome location and CD99 ... a gene shared by the human X and Y chromosomes". Cold Spring Harb. Symp. Quant. Biol. 51 (1): 205-12. doi:10.1101/SQB.1986.051. ... Unusually for a gene present on the X chromosome, the CD99 gene does not undergo X inactivation, and it was the first such ...
  https://en.wikipedia.org/wiki/CD99
*  EFHC2 - Wikipedia
The isoelectric point of EFHC2 is estimated to be 7.13 in humans. Relative to other proteins expressed in humans, EFHC2 has ... The first ninety base pairs compose the five prime untranslated region and the last 1913 base pairs compose the three prime ... EFHC2 is located on the negative strand (sense strand) of the X chromosome at p11.3. EFHC2 is also one of a few, select number ... A related protein, EFHC1 is encoded by a gene on chromosome 6. It has been suggested that both proteins are involved in the ...
  https://en.wikipedia.org/wiki/EFHC2
*  Objections to evolution - Wikipedia
For example, the fact that humans have one fewer pair of chromosomes than the great apes offered a testable hypothesis ... "Human Chromosome 2". PBS LearningMedia. PBS; WGBH Educational Foundation. 2007. Video segment from Nova's Judgment Day: ... The fusion hypothesis was confirmed in 2005 by discovery that human chromosome 2 is homologous with a fusion of two chromosomes ... Extra, inactive telomeres and centromeres remain on human chromosome 2 as a result of the fusion. The assertion of common ...
  https://en.wikipedia.org/wiki/Objections_to_evolution
*  Proline-rich protein 30 - Wikipedia
The PRR30 gene is located on the short arm of human chromosome 2 at band 2p23.3. It flanked by Prolactin regulatory element ... PRR30 has a length of 2618 base pairs of linear DNA. The PRR30 promoter directly flanks the gene and is 1162 base pairs in ... a resource of human open reading frames representing over 10,000 human genes". Genomics. 89 (3): 307-15. PMID 17207965. 7. NCBI ... PRR30 Splice Pattern Human protein PRR30 consists of 412 amino acid residues. It has a molecular weight of 44.7 kdal and an ...
  https://en.wikipedia.org/wiki/Proline-rich_protein_30
*  Common gamma chain - Wikipedia
The human IL2RG gene is located on the long (q) arm of the X chromosome at position 13.1, from base pair 70,110,279 to base ... Oyaizu N, Chirmule N, Kalyanaraman VS, Hall WW, Pahwa R, Shuster M, Pahwa S (March 1990). "Human immunodeficiency virus type 1 ... Ohbo K, Takasawa N, Ishii N, Tanaka N, Nakamura M, Sugamura K (March 1995). "Functional analysis of the human interleukin 2 ... DiSanto JP, Rieux-Laucat F, Dautry-Varsat A, Fischer A, de Saint Basile G (September 1994). "Defective human interleukin 2 ...
  https://en.wikipedia.org/wiki/Common_gamma_chain
*  Mutation - Wikipedia
For example, in the Homininae, two chromosomes fused to produce human chromosome 2; this fusion did not occur in the lineage of ... For example, a specific 32 base pair deletion in human CCR5 (CCR5-Δ32) confers HIV resistance to homozygotes and delays AIDS ... Changes in chromosome number may involve even larger mutations, where segments of the DNA within chromosomes break and then ... Ayala FJ, Coluzzi M (May 2005). "Chromosome speciation: humans, Drosophila, and mosquitoes". Proceedings of the National ...
  https://en.wikipedia.org/wiki/Mutation
*  C12orf66 - Wikipedia
"C12orf66 chromosome 12 open reading frame 66 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2017-02-25 ... C12orf66 variant 1 is 36 Mbp in length spanning the base pairs 64,186,312 - 64,222,296 on chromosome 12. There are 3 total ... The human C12orf66 protein is 446 amino acids in length with a molecular weight of 50kdal . C12orf66 contains the domain of ... C12orf66 is a protein that in humans is encoded by the C12orf66 gene. The C12orf66 protein is one of four proteins in the ...
  https://en.wikipedia.org/wiki/C12orf66
*  CD8 - Wikipedia
In humans, both genes are located on chromosome 2 in position 2p12. The CD8 co-receptor is predominantly expressed on the ... To function, CD8 forms a dimer, consisting of a pair of CD8 chains. The most common form of CD8 is composed of a CD8-α and CD8- ... PDB: 1cd8​; Leahy DJ, Axel R, Hendrickson WA (March 1992). "Crystal structure of a soluble form of the human T cell coreceptor ... T-cell Group - Cardiff University Mouse CD Antigen Chart Human CD Antigen Chart CD8 alpha - Marker for cytotoxic T lymphocytes ...
  https://en.wikipedia.org/wiki/CD8
*  WWC2 - Wikipedia
Locus The human gene WWC2 is found on chromosome 4 at band 4q35.1. The gene is found on the plus strand of the chromosome and ... is 8,822 base pairs long. The gene contains 23 exons. The WWC2 locus is quite complex and appears to produce several proteins ... Paralogs There are two paralogs of WWC2 found in humans, WWC1 and WWC3. WWC1 is located on chromosome 5 and is a probable ... WWC3 is located on chromosome X and not much is known about its function. Orthologs WWC2 is highly conserved in Mammalia, Aves ...
  https://en.wikipedia.org/wiki/WWC2
*  KRT23 - Wikipedia
Keratin, type I cytoskeletal 23 is a protein that in humans is encoded by the KRT23 gene. The protein encoded by this gene is a ... The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. The type I ... Genes Chromosomes Cancer. 30 (2): 123-35. doi:10.1002/1098-2264(2000)9999:9999<::AID-GCC1070>3.0.CO;2-W. PMID 11135429. ... Hesse M, Magin TM, Weber K (2002). "Genes for intermediate filament proteins and the draft sequence of the human genome: novel ...
  https://en.wikipedia.org/wiki/KRT23
*  Tmem261 - Wikipedia
Transmembrane protein 261 is a protein that in humans is encoded by the TMEM261 gene located on chromosome 9. TMEM261 is also ... TMEM261 is located at 9p24.1, its length is 91,891 base pairs (bp) on the reverse strand. Its neighbouring gene is PTPRD ... "9ORF123 chromosome 9 open reading frame 123". BioGRID: Database of Protein and Genetic Interactions. TyersLab. She X, Rohl CA, ... "The Human Protein Atlas:TMEM261". "EST profile: TMEM261". UniGene. National Library of Medicine. Wu J, et al. (2012). " ...
  https://en.wikipedia.org/wiki/Tmem261
*  NDUFA4L2 - Wikipedia
The NDUFA4L2 gene is located on the long q arm of chromosome 12 at position 13.3 and it spans 5,860 base pairs. NDUFA4L2 is a ... The human NDUFA4L2 gene codes for a subunit of Complex I of the respiratory chain, which transfers electrons from NADH to ... "Human PubMed Reference:". "Mouse PubMed Reference:". "Entrez Gene: NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 ... NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 is a protein that in humans is encoded by the NDUFA4L2 gene. The ...
  https://en.wikipedia.org/wiki/NDUFA4L2
*  FKBP6 - Wikipedia
FKBP6 is essential for homologous chromosome pairing in meiosis during spermatogenesis. Targeted inactivation of FKBP6 in mice ... FK506 binding protein 6, also known as FKBP6, is a human gene. The encoded protein shows structural homology to FKBP ... 2003). "Essential role of Fkbp6 in male fertility and homologous chromosome pairing in meiosis". Science. 300 (5623): 1291-5. ... Mutations in this gene have been associated with male infertility in humans. FKBP6 is deleted in Williams syndrome, however ...
  https://en.wikipedia.org/wiki/FKBP6
*  Sex hormone-binding globulin - Wikipedia
In humans common polymorphisms include the following: Rs6259, also called Asp327Asn location 7633209 on Chromosome 17, results ... Rs727428 position 7634474 is in several percent of humans. (TAAAA)(n) is five base pairs that repeats a variable number of ... Hryb DJ, Nakhla AM, Kahn SM, St George J, Levy NC, Romas NA, Rosner W (Jul 2002). "Sex hormone-binding globulin in the human ... In the womb the human fetus has a low level of SHBG allowing increased activity of sex hormones. After birth, the SHBG level ...
  https://en.wikipedia.org/wiki/Sex_hormone-binding_globulin
*  Proline-rich protein 21 - Wikipedia
It is encoded by the PRR21 gene, which is found on human chromosome 2, band 2q37.3. The gene exists in several species, both ... PRR21 consists of 389 amino acids or 1170 base pairs, all found within one exon. Like other proline-rich proteins, it contains ... "Human PubMed Reference:". "GeneCards". "National Center for Biotechnology Information". Williamson MP (January 1994). "The ... 297 ( Pt 2): 249-60. doi:10.1042/bj2970249. PMC 1137821 . PMID 8297327. "Proline-rich repeat" - via WikiMedia Commons. " ...
  https://en.wikipedia.org/wiki/Proline-rich_protein_21
*  List of organisms by chromosome count - Wikipedia
Crosland, M.W.J., Crozier, R.H. (1986). "Myrmecia pilosula, an ant with only one pair of chromosomes". Science. 231 (4743): ... 1992). "Evidence for an ancestral alphoid domain on the long arm of human chromosome 2". Human Genetics. 89 (2): 247-9. doi: ... Russian bionet site The dog through evolution Shared synteny of human chromosome 17 loci in Canids An atlas of the chromosome ... The list of organisms by chromosome count describes ploidy or numbers of chromosomes in the cells of various plants, animals, ...
  https://en.wikipedia.org/wiki/List_of_organisms_by_chromosome_count