*  Welcome to LibAge, the ageing reference resource
Chromosomal Proteins, Non-Histone *Chromosome Aberrations *DNA/genetics *DNA Damage/genetics *DNA Repair/physiology ... 2007) "A homozygous mutation in a novel zinc-finger protein, ERIS, is responsible for Wolfram syndrome 2." Am. J. Hum. Genet. ... 1998) "The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular ... 2016) "Life span extension by targeting a link between metabolism and histone acetylation in Drosophila." EMBO Rep. 17(3):455- ...
  http://libage.ageing-map.org/entries/tags/495/
*  Research Areas & Groups
... including protein folding/conformation and the interaction of proteins with small molecules, nucleic acids, or other proteins ... In order to achieve the same level of overall gene expression, they increase the transcription from most X chromosomal genes. ... Single-molecule nucleosome remodeling by INO80 and effects of histone tails. FEBS letters. ... Our laboratory investigates the mechanisms of chaperone-assisted protein folding, as well as how protein misfolding and ...
  http://qbm.genzentrum.lmu.de/research/research-areas-groups/
*  Researchers Study Mystery of the Toddler Who Won't Grow - Slashdot
Hundreds of thousands of proteins, peptides and RNAs running about that likely do something - we just don't know what. ... "has no apparent abnormalities in her endocrine system, no gross chromosomal abnormalities, or any of the other disruptions ... We can sequence the epigenome (both histone marks and DNA CpG methylation), the transcriptome, the translatome, and the ... that claim there are no known genetic disorders present or even chromosomal abnormalities and her telomeres seem to be ...
  https://science.slashdot.org/story/13/01/16/2028244/researchers-study-mystery-of-the-toddler-who-wont-grow?sdsrc=prev
*  Anti Histone H2BJ Antibody (PrecisionAb™ Polyclonal Antibody) | Bio-Rad Antibodies (formerly AbD Serotec)
Histone H2BJ antibody for detecting human histone H2B type 1-J. Validated on up to 12 cell lysates for western blotting. Try a ... Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. ... Rabbit anti Human histone H2BJ antibody recognizes Histone H2B type 1J, also known as histone H2B.1 and histone H2B/r. ... Rabbit anti human histone H2BJ antibody recognizes histone H2B type 1J, also known as HIST1H2BJ, H2B histone family, member R, ...
  https://www.bio-rad-antibodies.com/human-histone-h2bj-antibody-vpa00384.html
*  Biology Animations: The MAP-Kinase signalling pathway
protein detection * protein folding * protein receptors * protein secretion * protein structure * protein synthesis ...
  http://biology-animations.blogspot.com/2010/10/map-kinase-signalling-pathway.html
*  Specific Defects in Different Transcription Complexes Compensate for the Requirement of the Negative Cofactor 2 Repressor in...
Inostroza, J. A., F. H. Mermelstein, I. Ha, W. S. Lane and D. Reinberg, 1992 Dr1, a TATA-binding protein-associated ... 1992). NC2 consists of two subunits, NC2α (DRAP1) and NC2β (Dr1), which form a stable complex via histone fold domains (Goppelt ... when we transformed cells carrying a chromosomal deletion of BUR6 and the wild-type BUR6 gene on an URA3/CEN plasmid with YEp- ... Lee, T. I., and R. A. Young, 1998 Regulation of gene expression by TBP-associated proteins. Genes Dev. 12: 1398-1408. ...
  http://www.genetics.org/content/176/1/125
*  Anti-phospho-Histone H3 (Thr3) Antibody, clone JY325 (rabbit monoclonal) | 05-746R-25UL
... clone JY325 is a Rabbit Monoclonal Antibody for detection of phospho-Histone H3 (Thr3) also known as Histone H3.1 & has been ... Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. ... Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a ... Anti-phospho-Histone H3 (Thr3) Antibody, clone JY325 (rabbit monoclonal). 05-746R-25UL , Anti-phospho-Histone H3 (Thr3) ...
  http://www.merckmillipore.com/INTL/en/product/Anti-phospho-Histone-H3-Thr3-Antibody-clone-JY325-rabbit-monoclonal,MM_NF-05-746R-25UL
*  Soybean cultivar 6012078 - Patent application
0057]Protein Percent. Soybean seeds contain a considerable amount of protein. Protein is generally measured by NIR ... 81:581-588 (1991)); MAS (Velten et al., EMBO J. 3:2723-2730 (1984)) and maize H3 histone (Lepetit et al., Mol. Gen. Genetics ... concerning chromosomal location is useful for proprietary protection of a subject transgenic plant. If unauthorized propagation ... Foreign Protein Genes and Agronomic Genes [0092]With transgenic plants according to the present invention, a foreign protein ...
  http://www.patentsencyclopedia.com/app/20080250522
*  JCI - Welcome
Ribosomal proteins (RP) regulate specific gene expression by selectively translating subsets of mRNAs. Indeed, in Diamond- ... Vijay Sankaran and colleagues demonstrate that a mutation in the X-chromosomal gene encoding aminolevulinic acid synthase ... T cells led to profound changes in gene expression that were accompanied by alterations in DNA methylation at potential histone ... In Rnh1-deficient embryos, mRNA levels of Gata1 are normal, but GATA1 protein levels are decreased. At the molecular level, we ...
  https://taoyantao.com.www.mobile.jci.org/tags/23
*  Sample overview for 2507096
Inter-chromosomal Rearrangements Genome browser. Note that you can also view the genome browser in a separate page. ... B. Histone Modifications (ChIP-Seq): based on ChIP-Seq peak calls for histone modifications. ... This algorithm predicts the functional, molecular and phenotypic consequences of protein missense variants using hidden Markov ...
  http://cancer.sanger.ac.uk/cosmic/sample/overview?id=2507096
*  Rhabdomyosarcoma | Cancer Genetics Web
... which inhibits protein kinase Cα-mediated activation of mitogen-activated protein kinases (MAPKs), especially p38MAPK ... Amplification of chromosomal region 12q13-q14, which contains the CDK4 proto-oncogene, was identified in an aggressive subset ... We have also demonstrated increased trimethylation of histone H3 lysine 4 (H3K4me3) and preferential binding of Gli1, a known ... Mutated Genes and Abnormal Protein Expression (19). Clicking on the Gene or Topic will take you to a separate more detailed ...
  http://www.cancerindex.org/geneweb/X2002.htm
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
Green Fluorescent Proteins, Plant Proteins, Recombinant Proteins, Vaccines, Synthetic, Virus-Like Particle, Gene Transfer ... Stably transduced cells that carry the reporter construct within their chromosomal DNA will pass the reporter construct DNA to ... Cellular Biology, Issue 92, Induced pluripotent stem cells, iPSC, iPSC generation, human, HDAC inhibitors, histone deacetylase ... Glycosylation of proteins is the most prevalent post-translational modification found on proteins, and leads diversified ...
  https://www.jove.com/visualize/abstract/23110132/genetic-modification-cancer-cells-using-non-viral-episomal-smar
*  Sandwalk: Slip Slidin' Along - How DNA Binding Proteins Find Their Target
... but given the ubiquitous habit of histone compaction of large chromosomal segments, some portions of which obviously remain ... If it is, the protein binds very tightly and doesn't fall off. If it isn't, the interaction is much weaker and the protein ... They did this by labeling the lac repressor with a yellow flourescent protein and following the protein under a flourescent ... The notion that the chromosomal DNA molecule exists in all of its double-helical beauty for all proteins to probe seems rather ...
  https://sandwalk.blogspot.com/2012/07/slip-slidin-along-how-dna-binding.html
*  Fucci | MBL Life Science -JAPAN
Fucci-S/G2/M Green is a fusion protein of a fragment of human Geminin (amino acids 1-110) with the green fluorescent protein ... Blow, J. J., and Dutta, A., Preventing re-replication of chromosomal DNA. Nat. Rev. Mol. Cell Biol. 6, 476-486 (2005) PMID: ... Anti-Histone monoclonal antibodies Antibodies ... Tools for analyzing Protein-Protein interaction *FCS/FCCS ... Image based Protein-Protein interaction analysis "Fluoppi" [Outline] [Fluoppi Red] [Product list] ...
  http://ruo.mbl.co.jp/bio/e/product/flprotein/fucci.html
*  Dynamic DNA cytosine methylation in the Populus trichocarpa genome: tissue-level variation and relationship to gene expression ...
On a chromosomal scale, repeat regions were also correlated with genome gaps; the v2.2 assembly includes a large number (2,499 ... In order to determine patterns of 5meC relative to protein-coding genes, we used RPKM calculations to describe MeDIP-seq data ... Chan SW-L, Henderson IR, Zhang X, Shah G, Chien JS-C, Jacobsen SE: RNAi, DRD1, and histone methylation actively target ... Fewer MeDIP-seq reads mapped to chromosomal regions where gene density was higher (Additional file 8). Several high-coverage ...
  https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-13-27
*  Otto Hannes Vogel | Stanford Medicine Profiles
We demonstrate that the fluorescent in situ gene protein assay methodology is capable of resolving gene and protein patterns ... Chd5 requires PHD-mediated histone 3 binding for tumor suppression. Cell reports Paul, S., Kuo, A., Schalch, T., Vogel, H., ... By chromosomal engineering, we created rearranged chromosomes carrying the deletion [Df(11)17] or duplication [Dp(11)17] of the ... Gene-protein correlation in single cells NEURO-ONCOLOGY Renfrow, J. J., Scheck, A. C., Dhawan, N. S., Lukac, P. J., Vogel, H., ...
  https://med.stanford.edu/profiles/hannes-vogel
*  KMT2A Gene - GeneCards | KMT2A Protein | KMT2A Antibody
Protein Coding), Lysine Methyltransferase 2A, including: function, proteins, disorders, pathways, orthologs, and expression. ... Protein Symbol:. Q03164-KMT2A_HUMAN. Recommended name:. Histone-lysine N-methyltransferase 2A Protein Accession:. Q03164. ... Note=A chromosomal aberration involving KMT2A may be a cause of chronic neutrophilic leukemia. Translocation t(4;11)(q21;q23) ... Protein Expression for KMT2A Gene. See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=KMT2A
*  Another Set of Biomarkers
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. ... This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts ... As noted above, ETS1 is over-expressed and PDEF protein is often reduced or lost in human breast cancer. While further studies ... and a protein involved in histone acetylation (Hmgn2. ... The protein encoded by this gene is involved in the attachment ...
  http://terrymcgarty.blogspot.com/2016/02/another-set-of-biomarkers.html
*  Anti-CoREST3 / RCOR3 antibody (ab76921) | Abcam
Proteins and Peptides. Proteomics tools. Agonists, activators, antagonists and inhibitors. Lysates. Multiplex miRNA assays. By ... can mediate extraneuronal restriction by imposing either active repression via histone deacetylase recruitment or long term ... serves as a functional molecular beacon for the recruitment of molecular machinery that imposes silencing across a chromosomal ...
  http://www.abcam.com/corest3-rcor3-antibody-ab76921.html
*  Biology Animations: Retinal Ischemia Animation
protein detection * protein folding * protein receptors * protein secretion * protein structure * protein synthesis ...
  http://biology-animations.blogspot.com/2010/10/retinal-ischemia-animation.html
*  A conserved function for pericentromeric satellite DNA | eLife
The mouse HMGA1 protein was originally identified as an abundant non-histone component of mammalian chromatin (Goodwin et al., ... Isolation, properties and cellular distribution of D1, a chromosomal protein of Drosophila * C Rodriguez Alfageme ... Our ongoing research suggests that chromocenter formation involves protein-protein and protein-DNA interactions (also please ... D1 protein or D1-LacI fusion protein was expressed in a Drosophila strain in which LacO repeats are inserted in the distal ...
  https://elifesciences.org/articles/34122
*  Game-Changing Study: Epigenetic Memories are Passed Down 14 Successive Generations | Stillness in the Storm
Post-translational modifications of histone proteins is another epigenetic process. Histones help to package and condense the ... Effectively, this proves the existence of non-Mendelian transgenerational inheritance, where traits separate from chromosomal ... In a recent study, nematode worms were manipulated to harbor a transgene for a fluorescent protein, which made the worms glow ... Exosomes, which are synthesized by all plant and animal cells, contain distinct protein repertoires and are created when inward ...
  http://www.stillnessinthestorm.com/2017/11/game-changing-study-epigenetic-memories-are-passed-down-14-successive-generations.html
*  Difference between revisions of "Haynes:LitReviewNov2013" - OpenWetWare
2013) The histone demethylase LSD1/KDM1A promotes the DNA damage response. Nima Mosammaparast1, Haeyoung Kim, Benoit Laurent et ... 2013) A standard vector for the chromosomal integration and characterization of BioBrick™ parts in Escherichia coli . Susanna ... 2013) Whole-genome screening identifies proteins localized to distinct nuclear bodies. Ka-wing Fong, Yujing Li, Wenqi Wang et ... 2013) Chromatin Sampling-An Emerging Perspective on Targeting Polycomb Repressor Proteins. PLoS Genetics 9:8: 1-8. Link ...
  https://openwetware.org/wiki/?title=Haynes:LitReviewNov2013&diff=prev&oldid=755842
*  Early detection of diabetes - The Johns Hopkins University
... modification of proteins by the sugar N-acetylglucosamine) both causes insul ... and in particular the dynamic O-GlcNAcylation of proteins ( ... MGEA5 maps to a chromosomal region associated with late-onset ... Characterization of the histone acetyltransferase (HAT) domain of a bifunctional protein with activable OGlcNAcase and HAT ... Commercially available Protein-G or Protein A (Sigma; Pierce) coated plates will be used to directionally bind antibodies by ...
  http://www.freepatentsonline.com/9250248.html