*  Blood-cerebrospinal fluid barrier - Biology-Online Dictionary
Home » Blood-cerebrospinal fluid barrier. Blood-cerebrospinal fluid barrier a barrier located at the tight junctions which surround and connect the cuboidal epithelial cells on the surface of the choroid plexus; capillaries and connective tissue stroma of the choroid do not represent a barrier to protein tracers or dyes. ...
  http://www.biology-online.org/bodict/index.php?title=Blood-cerebrospinal_fluid_barrier&oldid=33110
*  Blood-cerebrospinal fluid barrier - Biology-Online Dictionary
Home » Blocq paul » Blomary » Blood-air barrier » Blood-aqueous barrier » Blood-cerebrospinal fluid barrier. Blood-cerebrospinal fluid barrier a barrier located at the tight junctions which surround and connect the cuboidal epithelial cells on the surface of the choroid plexus; capillaries and connective tissue stroma of the choroid do not represent a barrier to protein tracers or dyes. ...
  http://www.biology-online.org/dictionary/Blood-cerebrospinal_fluid_barrier
*  News: Unexpected link between choroid plexus and chronic pain - Aalto University
The choroid plexus located in the brain ventricle is marked with red in the brain image. The volume of the choroid plexus was measured in this work. The dots in the graph show the volume of the choroid plexus in patients with CRPS (on the left) and healthy control subjects (on the right). Each point corresponds to a single person.. Located in the walls of the brain ventricles, the choroid plexus is best known for producing cerebrospinal fluid, which forms a protective mechanical cushion and immunological buffer for the brain. It also controls the passage of many substances from the blood into the cerebrospinal fluid, brain, and spinal cord.. 'However, in clinical neuroscience, the functions of choroid plexus beyond cerebrospinal fluid generation have been largely neglected; for example, the size of the ...
  http://brainscience.aalto.fi/en/current/news/2015-09-21-003/
*  The fate of plasma protein which escapes from blood vessels of the choroid plexus of the rat--an electron microscope study. -...
Fenestrated blood vessels in the rat choroid plexus are permeable to dye-labelled proteins, HRP and ferritin. Most leakage appears to be via fenestrae but some additional escape of marker appears to take place through transient and reversible openings in the junctions between endothelial cells. After they have escaped into the choroidal stroma markers are prevented from entering the CSF by tight junctions between the epithelial cells which cover the choroid plexus, but how they are removed from the extravascular space is not known. Electron microscope study of rats who have been given multiple intravenous injections of ferritin shows that extravascular ferritin is take up both by connective tissue cells in the choroidal stroma and by choroidal epithelial cells. The findings suggest that the ingested protein is subsequently broken down within lysosomal vacuoles in the cytoplasm of these ...
  https://www.semanticscholar.org/paper/The-fate-of-plasma-protein-which-escapes-from-bloo-Hurley-Anderson/c384fd472b276173884b16578c6f1bdbab73c347
*  I Have Choroid Plexus Cyst
Do You Have Choroid Plexus Cyst? Join friendly people sharing true stories in the I Have Choroid Plexus Cyst group. Find support forums, advice and chat with groups who share this life experience. A Choroid Plexus Cyst anonymous support group with in...
  http://www.experienceproject.com/groups/Have-Choroid-Plexus-Cyst/90027
*  Women's response to fetal choroid plexus cysts detected by prenatal ultrasound.
OBJECTIVES: To determine maternal responses to detection of a minor structural variant, the choroid plexus cyst (CPC), in their fetus on prenatal ultrasound. STUDY DESIGN: We interviewed 34 pregnant women with an isolated CPC detected on mid-pregnanc
  http://www.biomedsearch.com/nih/Womens-response-to-fetal-choroid/16554849.html
*  Gelsolin Restores A-Induced Alterations in Choroid Plexus Epithelium
BioMed Research International is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies covering a wide range of subjects in life sciences and medicine. The journal is divided into 55 subject-specific sections.
  https://www.hindawi.com/journals/bmri/2010/805405/ref/
*  Frontiers | Cilia in the choroid plexus: their roles in hydrocephalus and beyond | Frontiers in Cellular Neuroscience
Cilia are whip-like projections that are widely conserved in eukaryotes and function as a motile propeller and/or sensory platform to detect various extracellular stimuli. In vertebrates, cilia are ubiquitously found in most cells, showing structural and functional diversities depending on the cell type. In this review, we focus on the structure and function of cilia in choroid plexus epithelial cells (CPECs). CPECs form one or two dozen non-motile 9+0 cilia, which display transient acquisition of motility during development. Genetic malfunction of cilia can lead to failure of multiple organs including the brain. Especially, several groups have demonstrated that the defects in CPEC cilia cause the communicating form of hydrocephalus. In order to elucidate the molecular mechanisms underlying the hydrocephalus, we have previously demonstrated that the cilia possess an NPFF receptor for autocrine signaling to regulate transepithelial fluid ...
  https://www.frontiersin.org/articles/10.3389/fncel.2015.00039/full
*  3R Research Foundation Switzerland / Projects / 3R-Project 91-04
Cells were isolated by mechanical and enzymatic treatment of freshly isolated porcine plexus tissue. Epithelial cell monolayers were grown and CSF secretion and transepithelial resistance were determined. The expression of f-actin as well as the choroid plexus marker protein transthyretin (TTR), were assessed. Permeability studies with marker compounds of different molecular weight were performed in order to assess monolayer integrity. The expression of the export proteins p-glycoprotein (Pgp, Abcb1) multidrug resistance protein1 (Mrp1, Abcc1) and Mrp4 (Abcc4) was studied by RT-PCR, Western-blot and immunofluorescence techniques and their functional activity was assessed by transport and uptake experiments.. Choroid plexus epithelial cells were isolated in high purity and grown to form confluent monolayers. Filter-grown monolayers displayed transendothelial resistance (TEER) values in the range of 100 to 150 Ohm x cm2. ...
  http://www.forschung3r.ch/en/projects/pr_91_04.html
*  AGENTS AND METHODS FOR TREATMENT OF ANXIETY DISORDERS - Patent application
0077]Adamec, R. E., P. Burton, et al. (1999). "Unilateral block of NMDA receptors in the amygdala prevents predator stress-induced lasting increases in anxiety-like behavior and unconditioned startle--effective hemisphere depends on the behavior." Physiol Behav 65(4-5): 739-51. [0078]Anisman, H., S. Lacosta, et al. (1998). "Stressor-induced corticotropin-releasing hormone, bombesin, ACTH and corticosterone variations in strains of mice differentially responsive to stressors." Stress 2(3): 209-20. [0079]Battle, T., L. Preisser, et al. (2000). "Vasopressin V1a receptor signaling in a rat choroid plexus cell line." Biochem Biophys Res Commun 275(2): 322-7. [0080]Carrithers, M. D., I. Visintin, et al. (2000). "Differential adhesion molecule requirements for immune surveillance and inflammatory recruitment." Brain 123 (Pt 6): 1092-101. [0081]Cohen, H., A. B. Geva, et al. (2007). "Post-traumatic stress behavioural responses in inbred mouse strains: can genetic predisposition ...
  http://www.patentsencyclopedia.com/app/20110033488
*  Roots of Childhood Brain Tumors - Vanderbilt-Ingram Cancer Center
Identifying the cellular origins of medulloblastoma - the most common malignant brain tumor in children - may help focus treatment on cell types responsible for tumor initiation. Previous research has linked Sonic hedgehog signaling in neuronal cell precursors within the developing cerebellum to medulloblastoma.. Now, Chin Chiang, Ph.D., and colleagues demonstrate that "turning on" Sonic hedgehog signaling in a different cell type - hindbrain roof plate cells - leads to medulloblastoma. The roof plate cells are a specialized tissue that function as a signaling center regulating neural patterning. Previous studies had suggested that the hindbrain roof plate was restricted in its potential and contributed only to non-neural choroid plexus epithelial cells.. The new studies, reported in April in PLoS ONE, demonstrate that the hindbrain roof plate contributes not only to choroid plexus but also to multiple neuronal and glial cell types in the ...
  https://news.vicc.org/2012/06/roots-of-childhood-brain-tumors/
*  Choroid Plexus Cyst
We had a pretty scary doctors appointment yesterday afternoon. The doctor told us he saw a Choroid Plexus Cyst on the baby's brain in the ultrasound. He said this fairly common and he has seen quite a few before. He said that the cyst alone does not cause any harm and usually goes away before delivery. However, he suggested we go to a Maternal and Fetal Specialist to have a more detailed ultrasound because the cyst along with other signs could mean the baby has Trisomy 18. I know one other sign they are looking for are clinched fist which we see in the pictures of the ultrasound but during the ultrasound she had her hand open at times and waving. Trisomy 18 is a chromosome disorder where the baby has two of the 18th chromosome. This usually results in a miscarriage or death soon after birth. My doctor said he has never seen a case where the cyst turns out to be Trisomy 18 and he said with my age we are much lower risk of this happening. He said usually by the time the ...
  http://heidbrinkhappenings.blogspot.com/2009/12/choroid-plexus-cyst.html
*  baby makes four: Choroid Plexus Cysts
I remember laying on the exam table and staring wide-eyed at Scott across the room wondering if his heart was pounding as hard as mine. "Your baby has two cysts on her brain, but don't worry." Yeah, right. I felt in a fog the rest of the ultrasound. We were supposed to meet with our doctor right after the ultrasound, but she was running late because of the morning snow fall. So, Scott and I went down to the cafe to wait, and we both just didn't know what to say. The card containing the news of whether we were having a boy or girl was laid to the side, and we just held hands across the table in the cafe. I didn't cry. I just didn't know what to think. After awhile, I pulled out my iPhone and googled the diagnosis. (I knew I shouldn't, but I just couldn't stop myself.) Immediately, I read choroid plexus cysts are a 'soft marker' for Trisomy 18, which is a very serious chromosomal abnormality. However, most babies with this condition also had other obvious developmental ...
  http://scottkristababywilliams.blogspot.com/2012/03/choroid-plexus-cysts.html
*  Dilated kidney...and choroid plexus cysts - Pregnancy: Ages 25-34 - MedHelp
Anyone else been told that their baby boy has a dilated kidney? I had my anatomy scan and doctor said he saw a choroid plexus cyst and dilated kidney. Said both are common I am just curious if any of y...
  http://www.medhelp.org/posts/Pregnancy-Ages-25-34/Dilated-kidneyand-choroid-plexus-cysts/show/1942961
*  Choroid Plexus Cyst??? - Pregnancy: Age 35+ - MedHelp
Had my 20 wk ultrasound today and everything was fine except there was a choroid plexus cyst. My quad screen was all normal. I'm wondering if this is something to worry about? Or just take it as a chan...
  http://www.medhelp.org/posts/Pregnancy-Age-35/Choroid-Plexus-Cyst/show/1898695
*  'ciliary body' Protocols and Video...
Video articles in JoVE about ciliary body include 'Evaluation of Planar-Cell-Polarity Phenotypes in Ciliopathy Mouse Mutant Cochlea', 'Observation of the Ciliary Movement of Choroid Plexus Epithelial Cells Ex Vivo', 'Ultrasound Cyclo Plasty in Eyes with Glaucoma', 'Application of High-speed Super-resolution SPEED Microscopy in Live Primary Cilium', 'Using Primary Neurosphere Cultures to Study Primary Cilia', 'Simulating the Mechanics of Lens Accommodation Via a Manual Lens Stretcher', 'Acute Dissociation of Lamprey Reticulospinal Axons to Enable Recording from the Release Face Membrane of Individual Functional Presynaptic Terminals', 'Eye Exam', 'Dissection of Human Vitreous Body Elements for Proteomic Analysis', 'A Simplified Technique for In situ Excision of Cornea and Evisceration of Retinal Tissue from Human Ocular Globe', 'Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation', 'Evaluation of Zebrafish Kidney Function Using a Fluorescent ...
  https://www.jove.com/keyword/ciliary+body
*  Body Fluid Differential Tutorial
If you have forgotten the art of differentiating choroid plexus cells from ependymal cells or viral lymphocytes from fluid monocytes, you are in luck! This course provides a thorough morphologic identification of over 40 cell types and disease states to recharge your memory. The course features over 100 crystal clear, perfectly stained body fluid images to illustrate both basic and advanced cellular morphology - perfect for a comprehensive, detailed review which can help refresh any technologist, both in or out of the hematology laboratory. The course is P.A.C.E. approved for 2 full credit hours to help reach your continuing education credit requirements. Enjoy learning and/or reviewing the key identification characteristics of body fluid cells in a user-friendly and fun format. Enroll today!. See all available courses ». ...
  https://www.labce.com/body_fluid_differential_tutorial.aspx
*  choroid plexus Archives - NeuroQuest
by NeuroQuest , Oct 3, 2014 , Research. Aging-associated cognitive decline is affected by factors produced inside and outside the brain. Using multi-organ genome-wide analysis of aged mice, we found that the choroid plexus, an interface between the brain and the circulation, shows a type I interferon ...
  http://neuro-quest.com/tag/choroid-plexus/
*  Relationship between immunoglobulin levels in cerebrospinal fluid and serum]. - Semantic Scholar
By means of radial immunodiffusion, immunoglobulins A, G, M and albumin were determined in serum and unconcentrated cerebrospinal fluid from 182 controls and 141 patients. Concentrations in cerebrospinal fluid and serum of patients did not correlate, not even in those groups whose elevated immunoglobulin and albumin concentrations in cerebrospinal fluid resulted from damage to the blood-cerebrospinal fluid barrier, as in inflammatory diseases and neoplastic processes of the central nervous system or of the meninges.--Concentrations of immunoglobulins in cerebrospinal fluid should therefore be evaluated independently of the serum concentrations. Cerebrospinal fluid and serum constitute samples from two separate compartments which are capable of independent immune reactions.
  https://www.semanticscholar.org/paper/Relationship-between-immunoglobulin-levels-in-cer-Weisner-Bernhardt/ad575ddfaade7d3616ea7e07ac8c10ec05d2f234
*  choroid plexus cyst - Complications | Forums | What to Expect
I just got back from the doctored and he said on the last (stage2) ultrasound they did they saw this cyst on the baby's brain. Does anyone know about...
  https://www.whattoexpect.com/forums/complications/topic/choroid-plexus-cyst-706.html
*  Choroid Plexus Cysts
Jesus follower, wife to the Marine, Mama to 4, Hover Lover, Health Nut, and a creator of many beautiful things. I opened Skidz Wife Creations to create unique items for you and your home, to share my love of sewing around the world, & to provide retirement income and planning for our home. Thank-you for visiting our store and bringing my dreams to life! I became a health coach to improve my lives and those that I can minister to ...
  http://2003beachbunch.blogspot.com/2013/10/choroid-plexus-cysts.html
*  Identification of RALDH2 as a Visually Regulated Retinoic Acid Synthesizing Enzyme in the Chick Choroid | IOVS | ARVO Journals
To determine whether increased expression of RALDH2 in recovering choroids resulted in increased retinoic acid synthesis, atRA was measured in organ cultures of choroids during the period in which RALDH2 expression was increasing, using an ultrasensitive procedure making use of LC/MS/MS quantification (Fig. 8A). Choroids (8-mm punches) isolated from control and treated eyes after recovery periods ranging from 3 hours to 15 days were incubated in N2 culture medium (80 μL) for 3 hours, and total atRA was measured in medium together with the choroid punch. Control samples contained on average 0.33 to 0.60 pmol atRA, corresponding to concentrations of approximately 4 × 10−9 to 7 × 10−9 M in organ cultures. After 6 hours of recovery, atRA concentrations began to increase in treated eyes. The large SE is due to one choroid from a recovering eye that synthesized nearly fourfold more RA than the other samples. RA concentration was ...
  http://iovs.arvojournals.org/article.aspx?articleid=2188954
*  Plus it
The uptake of [3H]AZT into the CNS was measured using the bilateral perfusion technique over 30 min in the anesthetized guinea pig and found to be significantly greater than the uptake of the inert polar molecule d-[14C]mannitol (fig.1). This suggests that [3H]AZT can measurably cross the BBB and blood-CSF barrier and enter the brain and CSF. In contrast to these results, the brain uptake of [3H]AZT measured in earlier studies using the single-pass technique (,30 sec) was extremely low and not significantly higher than the brain extraction of [14C]sucrose that does not measurably cross the BBB (Ellison et al., 1988; Terasaki and Pardridge, 1988). Several other studies have also suggested that AZT cannot significantly cross the BBB (Ahmed et al., 1991; De Miranda et al., 1990; Galinsky et al., 1990) and can only enter the brain via the choroid plexus/CSF pathway (Ellisonet al., 1988; Galinsky et al., 1990; Terasaki and Pardridge, 1988). It is interesting to note that using ...
  http://jpet.aspetjournals.org/content/281/3/1211
*  Molecularly and temporally separable lineages form the hindbrain roof plate and contribute differentially to the choroid plexus...
Recent genetic fate maps show that the mouse hRPe at ∼E11 is comprised of lineage-restricted compartments along the AP dimension (Awatramani et al., 2003) - a contrast to the AP cell dispersion characterizing floor plate (Fraser et al., 1990). Here, we re-examined our earlier finding of hRPe segmentation using a genetic fate mapping indicator allele with improved sensitivity due to encoding a nuclear-localized βgal (nβgal) as lineage tracer (Farago et al., 2006). We coupled this new Cre-responsive nβgal indicator allele with recombinase transgene Egr2::cre (Voiculescu et al., 2000) to map hRPe emerging from rhombomeres 3 and 5 (r3 and r5). As predicted (Awatramani et al., 2003), nβgal-positive (nβgal+) cells were found in stripes in the lateral hRPe at ∼E11.5, supporting the model that these cells develop in a segmental, lineage-restricted fashion (Fig. 2B, lat). Not predicted was our detection of a midline hRPe field harboring an admixture of cells derived from different rhombomeres - ...
  http://dev.biologists.org/content/134/19/3449
*  Tissue involved in brain development may offer new approach to stroke...( The same tissue that helps a developing...)
Health,The same tissue that helps a developing brain form its protective bloo...The choroid plexus has been relegated as a bystander in the adult b...But within the last five years researchers across the world have b...This latest study is the first to show the therapeutic potential of... The transplanted choroid plexus may provide a potential new therap...,Tissue,involved,in,brain,development,may,offer,new,approach,to,stroke,treatment,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
  http://news.bio-medicine.org/medicine-news-2/Tissue-involved-in-brain-development-may-offer-new-approach-to-stroke-treatment-3048-1/